Rajashri Mane - Academia.edu (original) (raw)
Papers by Rajashri Mane
Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Diabetes mellitus cases are increasing worldwide. It affects almost all systems of t... more Introduction Diabetes mellitus cases are increasing worldwide. It affects almost all systems of the body including audio-vestibular system. Diabetic otopathy (DO) is the presence of symptoms and signs of vestibular and auditory disorders in patients with diabetes mellitus after the exclusion of other causes. In this review we aimed to study the mechanism of development of hearing loss in diabetes, the relationship between duration and severity of diabetes, and association of other complications with hearing loss. Materials and Methods We searched the MEDLINE & PubMed database using terms ‘diabetic otopathy’ and ‘diabetes & hearing loss’ for the articles published since 1970. Twenty articles were selected and reviewed. Results The mechanism of development of DO is not yet clearly known. But it is suggested to be multifactorial. This review of literature suggested that hearing impairment is two times more prevalent in subjects with diabetes as compared to those without diabetes. The ...
INDIAN JOURNAL OF APPLIED RESEARCH
Background: Chronic tonsillitis is a common pathology in Indian population. However, tonsillectom... more Background: Chronic tonsillitis is a common pathology in Indian population. However, tonsillectomy is rarely preferred by adults owing to the anticipated post-operative pain and complications. Therefore, the benets of tonsillectomy in adults needs to be established. Aim:To evaluate the quality of life in adults with chronic tonsillitis undergoing tonsillectomy as compared to conservative treatment. Methodology:Atotal of 64 patients (n=44, tonsillectomy; n=20, conservative treatment) from 18-50 years were enrolled in a prospective cohort study. Patients with quinsy and malignancy of tonsils, sleep apnea were excluded. Tonsillectomy was performed by dissection and snare method. Patients were asked to ll a questionnaire, before and one year after the procedure in order to evaluate the impact of the procedure on their quality of life. Post-operative improvement in Quality of life (QoL) was assessed by Wilcoxon-sign rank test and proportion test using R studio (v 1.2.5001). Pvalue of ≤...
Head and neck cancer is a major problem in our country constituting around one-third of all cance... more Head and neck cancer is a major problem in our country constituting around one-third of all cancer cases in contrast to 4-5% in the developed world. The incidence of tobacco-related head and neck cancers in the western countries has declined due to decreased use of tobacco. Parallel to this decrease, there has been an increase in Human Papilloma virus (HPV) related oral cancers. In India also some attempts are made by the government to decrease the use of tobacco. However, the changing epidemiology seen there, is not seen here. We searched Pub Med database for literature published from 1985 to 2013 reporting any relationship between HPV and oral cancers to know why there is this difference in carcinogenic process.
Indian journal of pathology & microbiology, 2000
A specific subtype of teratoid tumour occurring in nasopharynx and oropharynx has been mentioned ... more A specific subtype of teratoid tumour occurring in nasopharynx and oropharynx has been mentioned as 'hairy polyp'. This is a rare lesion and is to be differentiated from true teratomas. A case of hairy polyp of nasopharynx in a 12 year old girl is reported.
Indian Journal of Otolaryngology and Head and Neck Surgery, 2006
Indian Journal of Otolaryngology and Head & Neck Surgery, 2013
A theoretical risk of iatrogenic sensorineural hearing loss during surgery has induced a reluctan... more A theoretical risk of iatrogenic sensorineural hearing loss during surgery has induced a reluctance to perform bilateral tympanoplasty type I among some otosurgeons. This paper presents results of bilateral surgery in 14 patients (28 ears). Fourteen patients with bilateral, dry tympanic membrane perforations caused by chronic otitis media were selected prospectively for bilateral tympanoplasty type I (28 ears) at a tertiary referral center. All patients had a HL corresponding to the size and localization of the perforation (no suspicion of ossicular chain defect or other pathology). Mean age was 37.5 years. There were seven males and seven females in our study. All but five ears were operated through an endaural or endomeatal approach, and five ears operated by postaural approach. The Underlay technique was used in all cases. Total ten cases operated using Fascia Lata and four cases operated using Temporalis fascia as graft material. Follow-up examination and hearing tests (pure tone audiometry) were performed up to 20 months after surgery. The graft take rate was 96%, with no retraction pockets or displaced grafts observed during follow-up. One patient had small residual perforation which healed at the end of 3 months. Hearing improved significantly, and the air-bone gap was significantly reduced. The air-bone gap was closed to within 10 dB in 92% and within 20 dB in 100% of the ears. Surprisingly good hearing was found during postoperative, bilateral ear canal gauze packing. Iatrogenic sensorineural HL did not occur. We conclude that bilateral myringoplasty is safe, with good results, reduces costs, and leaves the patient satisfied. The hearing impairment during postoperative ear canal packing is surprisingly modest and readily acceptable by the patients.
Indian Journal of Otolaryngology and Head & Neck Surgery, 2013
Septoplasty is routinely performed for symptomatic deviated nasal septum. The most unpleasant par... more Septoplasty is routinely performed for symptomatic deviated nasal septum. The most unpleasant part of this procedure is the pain during removal of nasal pack. The objective of this study was to compare the results of septoplasty with and without post-operative nasal packing and thereby assess the necessity of nasal packing after septoplasty. This descriptive study was carried out in ENT Department of D.Y. Patil Hospital, Kolhapur. 50 patients between the age groups of 18-50 years, having symptomatic deviated septum were selected. Out of which 25 patients underwent septoplasty with packing and 25 patients underwent septoplasty without packing with quilting sutures taken on the septum. Patients who underwent septoplasty without packing, experienced less pain and bleeding was minimal. Only one patient developed septal hematoma postoperatively. All the patients were satisfied at the end of 3 months. Simple DNS can be safely treated with septoplasty without Anterior Nasal Packing and by taking Quilting sutures on the septum. The sutures are also useful for closing any inadvertent tears of the septal mucosa and providing additional support for the cartilage pieces retained in septoplasty. Nasal packing should be should be reserved only for the patients with increased risk of bleeding.
Clinical Rhinology An International Journal, 2012
Mucormycosis refers to a severe infection with fungi of order Mucorales, seen in diabetic and imm... more Mucormycosis refers to a severe infection with fungi of order Mucorales, seen in diabetic and immunocompromised patients. Rhino-orbito-cerebral mucormycosis is known to exist in two forms, the well-known acute form and the less well-recognized chronic form. The most common presenting features of the chronic form are ophthalmologic, including ptosis, proptosis, visual loss and ophthalmoplegia. Here, we report a case of chronic rhinocerebral mucormycosis (RCM) presented with nonhealing oroantral fistula in a diabetic patient without any orbital symptoms. We are reporting this case for its unusual presentation. How to cite this article Mane RS, Patil BC, Mohite AA. Rhinocerebral Mucormycosis Presenting as Oroantral Fistula. Clin Rhinol An Int J 2012;5(3):135-137.
Indian Journal of Otolaryngology and Head & Neck Surgery
The aim of this study is to highlight involvement of facial nerve as a presenting symptom in rhin... more The aim of this study is to highlight involvement of facial nerve as a presenting symptom in rhino cerebral mucormycosis. A retrospective longitudinal study was carried out for a period of 1 year from May 2017 to May 2018 in Department of Otorhinolaryngology of Dr. D. Y. Patil Medical College and Hospital, Kolhapur. The usual presentation include nasal stuffiness, headache, eye pain and orbital swelling, ophthalmoplegia and visual loss. However we had four patients who presented to our OPD with facial nerve palsy and rhino cerebral mucormycosis. All four patients were diabetic. The available clinical and laboratory data was retrospectively collected and analyzed. Facial nerve palsy is an unusual but significant sign in presentation of mucormycosis. It could be misdiagnosed as CVA with subsequent delay in the treatment. A high index of suspicion for mucormycosis in diabetic patients presenting with facial palsy will be helpful in achieving early and accurate diagnosis with prompt management and better outcome.
Indian Journal of Otolaryngology and Head & Neck Surgery, 2014
ABSTRACT A prospective, cohort, clinical study was conducted at Dr. D. Y. Patil Hospital, Kolhapu... more ABSTRACT A prospective, cohort, clinical study was conducted at Dr. D. Y. Patil Hospital, Kolhapur from August 2010 to August 2013. The aim was to evaluate the results of type 1 interlay tympanoplasty with respect to graft uptake, hearing improvement and complications. Total of 100 cases with a mucosal type of chronic suppurative otitis media and a large central perforation (involving more than 50 % of tympanic membrane) were operated for type 1 tympanoplasty where the graft was placed by interlay method (below the fibro-squamous layer and above the mucosal or endothelial layer). Patients were followed up with ear microscopy at each follow up visit and an audiometry at the end of 3rd month. Statistical analysis was done by statcal software using paired t test and two sample t test for proportion. 96 (96 %) cases had a successful graft uptake. The mean pre-operative air-bone gap was 36.42 ± 12.0 dB; whereas the mean post-operative air-bone gap was 9.7 ± 6.71 dB. Except for residual perforation in four patients and partial tympanomeatal flap necrosis in two patients no other complications were encountered. Thus, we conclude that, the interlay tympanoplasty is a safe and effective method of graft placement for large central perforation.
International Journal of Otorhinolaryngology and Head and Neck Surgery
Chronic suppurative otitis media is a disease associated with complications if not managed in tim... more Chronic suppurative otitis media is a disease associated with complications if not managed in time. Due to ignorance, poor literacy and late presentation the management becomes challenging and difficult. Inspite of the advent of higher antibiotics, chronic otitis media poses a threat to ENT surgeons because of the varied intra cranial and extra cranial complications that can be encountered. These complications are caused by progressive erosion of the bone thus increasing the risk of damage to exposed labyrinth, the dura and facial nerve. Prior to antibiotic era, intracranial (IC) complications occurred in 2.3-4% cases. With the advent of newer antibiotics and newer surgical techniques, the complication have been greatly reduced from 2.3-4% to 0.15-0.04%. 1 Likewise a decline in mortality has been seen from 25 to 8%. Though there is an overall decline in the rate of complications of otitis media, life threatening complications are still seen to exist. The reasons behind ABSTRACT Background: Chronic suppurative otitis media is a disease that can end up in complications when treatment is delayed. The present prospective study was conducted at our tertiary care hospital and teaching centre to evaluate the incidence of complications of CSOM and their management. Methods: We analysed the clinical and intra operative findings, type of medical and surgical management and recovery of the patient. Results: Total 20 cases of CSOM with complications were reviewed in study period of 5 years. Of these 20 cases, 14 cases had extracranial (EC) while 6 cases had intracranial (IC) complications. The encountered IC complications were brain abscess ie temporal lobe abscess, pyogenic meningitis, lateral sinus thrombophlebitis and extradural abscess. Among the EC complications, mastoid abscess, Bezolds abscess, zygomatic abscess and labyrinthitis were encountered. The IC complications presented with fever, headache, and signs of meningeal irritation. Pseudomonas aeruginosa, Proteus, Staphylococcus epidermidis and E. coli were the common organisms isolated. Both groups of patients had cholesteatoma and middle ear granulations. Surgery was the main modality of treatment with zero mortality rate. We reviewed the clinical presentation and management in both groups. Conclusions: CSOM complications, inspite of their reduced incidence still pose a great challenge in developing countries. When the disease presents late, it lead to difficulty in management and consequently higher mortality. Our study emphasizes the importance of early diagnosis and prompt management.
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2007
According to WHO, there will be epidemic of diabetes world over and India is going to be 'A d... more According to WHO, there will be epidemic of diabetes world over and India is going to be 'A diabetes capital of the world' by 2025. With the increasing incidence of diabetes, the associated complications are also bound to increase. Rhinocerebral mucormycosis is one of them.Rhinocerebral Mucormycosis is an opportunistic, fulminating fungal infection, caused by Rhizopus species of order of mucorales, frequently seen in diabetic and immunocompromised patients. Mucormycosis has a very high mortality rate.Early diagnosis and treatment with Amphotericin-B is the key to combat this disease successfully. We have seen 13 cases in last 3 years (2002-2005) in our area. This incidence is significant, as this type of cases were rarely seen before 2002, in this geographical area. We present an account of these cases; treatment strategies adopted, review of literature, and highlight 'the role of ENT surgeon in diagnosis and management of this dreadful disease'.
Bengal Journal of Otolaryngology and Head Neck Surgery
Introduction Diabetes mellitus cases are increasing worldwide. It affects almost all systems of t... more Introduction Diabetes mellitus cases are increasing worldwide. It affects almost all systems of the body including audio-vestibular system. Diabetic otopathy (DO) is the presence of symptoms and signs of vestibular and auditory disorders in patients with diabetes mellitus after the exclusion of other causes. In this review we aimed to study the mechanism of development of hearing loss in diabetes, the relationship between duration and severity of diabetes, and association of other complications with hearing loss. Materials and Methods We searched the MEDLINE & PubMed database using terms ‘diabetic otopathy’ and ‘diabetes & hearing loss’ for the articles published since 1970. Twenty articles were selected and reviewed. Results The mechanism of development of DO is not yet clearly known. But it is suggested to be multifactorial. This review of literature suggested that hearing impairment is two times more prevalent in subjects with diabetes as compared to those without diabetes. The ...
INDIAN JOURNAL OF APPLIED RESEARCH
Background: Chronic tonsillitis is a common pathology in Indian population. However, tonsillectom... more Background: Chronic tonsillitis is a common pathology in Indian population. However, tonsillectomy is rarely preferred by adults owing to the anticipated post-operative pain and complications. Therefore, the benets of tonsillectomy in adults needs to be established. Aim:To evaluate the quality of life in adults with chronic tonsillitis undergoing tonsillectomy as compared to conservative treatment. Methodology:Atotal of 64 patients (n=44, tonsillectomy; n=20, conservative treatment) from 18-50 years were enrolled in a prospective cohort study. Patients with quinsy and malignancy of tonsils, sleep apnea were excluded. Tonsillectomy was performed by dissection and snare method. Patients were asked to ll a questionnaire, before and one year after the procedure in order to evaluate the impact of the procedure on their quality of life. Post-operative improvement in Quality of life (QoL) was assessed by Wilcoxon-sign rank test and proportion test using R studio (v 1.2.5001). Pvalue of ≤...
Head and neck cancer is a major problem in our country constituting around one-third of all cance... more Head and neck cancer is a major problem in our country constituting around one-third of all cancer cases in contrast to 4-5% in the developed world. The incidence of tobacco-related head and neck cancers in the western countries has declined due to decreased use of tobacco. Parallel to this decrease, there has been an increase in Human Papilloma virus (HPV) related oral cancers. In India also some attempts are made by the government to decrease the use of tobacco. However, the changing epidemiology seen there, is not seen here. We searched Pub Med database for literature published from 1985 to 2013 reporting any relationship between HPV and oral cancers to know why there is this difference in carcinogenic process.
Indian journal of pathology & microbiology, 2000
A specific subtype of teratoid tumour occurring in nasopharynx and oropharynx has been mentioned ... more A specific subtype of teratoid tumour occurring in nasopharynx and oropharynx has been mentioned as 'hairy polyp'. This is a rare lesion and is to be differentiated from true teratomas. A case of hairy polyp of nasopharynx in a 12 year old girl is reported.
Indian Journal of Otolaryngology and Head and Neck Surgery, 2006
Indian Journal of Otolaryngology and Head & Neck Surgery, 2013
A theoretical risk of iatrogenic sensorineural hearing loss during surgery has induced a reluctan... more A theoretical risk of iatrogenic sensorineural hearing loss during surgery has induced a reluctance to perform bilateral tympanoplasty type I among some otosurgeons. This paper presents results of bilateral surgery in 14 patients (28 ears). Fourteen patients with bilateral, dry tympanic membrane perforations caused by chronic otitis media were selected prospectively for bilateral tympanoplasty type I (28 ears) at a tertiary referral center. All patients had a HL corresponding to the size and localization of the perforation (no suspicion of ossicular chain defect or other pathology). Mean age was 37.5 years. There were seven males and seven females in our study. All but five ears were operated through an endaural or endomeatal approach, and five ears operated by postaural approach. The Underlay technique was used in all cases. Total ten cases operated using Fascia Lata and four cases operated using Temporalis fascia as graft material. Follow-up examination and hearing tests (pure tone audiometry) were performed up to 20 months after surgery. The graft take rate was 96%, with no retraction pockets or displaced grafts observed during follow-up. One patient had small residual perforation which healed at the end of 3 months. Hearing improved significantly, and the air-bone gap was significantly reduced. The air-bone gap was closed to within 10 dB in 92% and within 20 dB in 100% of the ears. Surprisingly good hearing was found during postoperative, bilateral ear canal gauze packing. Iatrogenic sensorineural HL did not occur. We conclude that bilateral myringoplasty is safe, with good results, reduces costs, and leaves the patient satisfied. The hearing impairment during postoperative ear canal packing is surprisingly modest and readily acceptable by the patients.
Indian Journal of Otolaryngology and Head & Neck Surgery, 2013
Septoplasty is routinely performed for symptomatic deviated nasal septum. The most unpleasant par... more Septoplasty is routinely performed for symptomatic deviated nasal septum. The most unpleasant part of this procedure is the pain during removal of nasal pack. The objective of this study was to compare the results of septoplasty with and without post-operative nasal packing and thereby assess the necessity of nasal packing after septoplasty. This descriptive study was carried out in ENT Department of D.Y. Patil Hospital, Kolhapur. 50 patients between the age groups of 18-50 years, having symptomatic deviated septum were selected. Out of which 25 patients underwent septoplasty with packing and 25 patients underwent septoplasty without packing with quilting sutures taken on the septum. Patients who underwent septoplasty without packing, experienced less pain and bleeding was minimal. Only one patient developed septal hematoma postoperatively. All the patients were satisfied at the end of 3 months. Simple DNS can be safely treated with septoplasty without Anterior Nasal Packing and by taking Quilting sutures on the septum. The sutures are also useful for closing any inadvertent tears of the septal mucosa and providing additional support for the cartilage pieces retained in septoplasty. Nasal packing should be should be reserved only for the patients with increased risk of bleeding.
Clinical Rhinology An International Journal, 2012
Mucormycosis refers to a severe infection with fungi of order Mucorales, seen in diabetic and imm... more Mucormycosis refers to a severe infection with fungi of order Mucorales, seen in diabetic and immunocompromised patients. Rhino-orbito-cerebral mucormycosis is known to exist in two forms, the well-known acute form and the less well-recognized chronic form. The most common presenting features of the chronic form are ophthalmologic, including ptosis, proptosis, visual loss and ophthalmoplegia. Here, we report a case of chronic rhinocerebral mucormycosis (RCM) presented with nonhealing oroantral fistula in a diabetic patient without any orbital symptoms. We are reporting this case for its unusual presentation. How to cite this article Mane RS, Patil BC, Mohite AA. Rhinocerebral Mucormycosis Presenting as Oroantral Fistula. Clin Rhinol An Int J 2012;5(3):135-137.
Indian Journal of Otolaryngology and Head & Neck Surgery
The aim of this study is to highlight involvement of facial nerve as a presenting symptom in rhin... more The aim of this study is to highlight involvement of facial nerve as a presenting symptom in rhino cerebral mucormycosis. A retrospective longitudinal study was carried out for a period of 1 year from May 2017 to May 2018 in Department of Otorhinolaryngology of Dr. D. Y. Patil Medical College and Hospital, Kolhapur. The usual presentation include nasal stuffiness, headache, eye pain and orbital swelling, ophthalmoplegia and visual loss. However we had four patients who presented to our OPD with facial nerve palsy and rhino cerebral mucormycosis. All four patients were diabetic. The available clinical and laboratory data was retrospectively collected and analyzed. Facial nerve palsy is an unusual but significant sign in presentation of mucormycosis. It could be misdiagnosed as CVA with subsequent delay in the treatment. A high index of suspicion for mucormycosis in diabetic patients presenting with facial palsy will be helpful in achieving early and accurate diagnosis with prompt management and better outcome.
Indian Journal of Otolaryngology and Head & Neck Surgery, 2014
ABSTRACT A prospective, cohort, clinical study was conducted at Dr. D. Y. Patil Hospital, Kolhapu... more ABSTRACT A prospective, cohort, clinical study was conducted at Dr. D. Y. Patil Hospital, Kolhapur from August 2010 to August 2013. The aim was to evaluate the results of type 1 interlay tympanoplasty with respect to graft uptake, hearing improvement and complications. Total of 100 cases with a mucosal type of chronic suppurative otitis media and a large central perforation (involving more than 50 % of tympanic membrane) were operated for type 1 tympanoplasty where the graft was placed by interlay method (below the fibro-squamous layer and above the mucosal or endothelial layer). Patients were followed up with ear microscopy at each follow up visit and an audiometry at the end of 3rd month. Statistical analysis was done by statcal software using paired t test and two sample t test for proportion. 96 (96 %) cases had a successful graft uptake. The mean pre-operative air-bone gap was 36.42 ± 12.0 dB; whereas the mean post-operative air-bone gap was 9.7 ± 6.71 dB. Except for residual perforation in four patients and partial tympanomeatal flap necrosis in two patients no other complications were encountered. Thus, we conclude that, the interlay tympanoplasty is a safe and effective method of graft placement for large central perforation.
International Journal of Otorhinolaryngology and Head and Neck Surgery
Chronic suppurative otitis media is a disease associated with complications if not managed in tim... more Chronic suppurative otitis media is a disease associated with complications if not managed in time. Due to ignorance, poor literacy and late presentation the management becomes challenging and difficult. Inspite of the advent of higher antibiotics, chronic otitis media poses a threat to ENT surgeons because of the varied intra cranial and extra cranial complications that can be encountered. These complications are caused by progressive erosion of the bone thus increasing the risk of damage to exposed labyrinth, the dura and facial nerve. Prior to antibiotic era, intracranial (IC) complications occurred in 2.3-4% cases. With the advent of newer antibiotics and newer surgical techniques, the complication have been greatly reduced from 2.3-4% to 0.15-0.04%. 1 Likewise a decline in mortality has been seen from 25 to 8%. Though there is an overall decline in the rate of complications of otitis media, life threatening complications are still seen to exist. The reasons behind ABSTRACT Background: Chronic suppurative otitis media is a disease that can end up in complications when treatment is delayed. The present prospective study was conducted at our tertiary care hospital and teaching centre to evaluate the incidence of complications of CSOM and their management. Methods: We analysed the clinical and intra operative findings, type of medical and surgical management and recovery of the patient. Results: Total 20 cases of CSOM with complications were reviewed in study period of 5 years. Of these 20 cases, 14 cases had extracranial (EC) while 6 cases had intracranial (IC) complications. The encountered IC complications were brain abscess ie temporal lobe abscess, pyogenic meningitis, lateral sinus thrombophlebitis and extradural abscess. Among the EC complications, mastoid abscess, Bezolds abscess, zygomatic abscess and labyrinthitis were encountered. The IC complications presented with fever, headache, and signs of meningeal irritation. Pseudomonas aeruginosa, Proteus, Staphylococcus epidermidis and E. coli were the common organisms isolated. Both groups of patients had cholesteatoma and middle ear granulations. Surgery was the main modality of treatment with zero mortality rate. We reviewed the clinical presentation and management in both groups. Conclusions: CSOM complications, inspite of their reduced incidence still pose a great challenge in developing countries. When the disease presents late, it lead to difficulty in management and consequently higher mortality. Our study emphasizes the importance of early diagnosis and prompt management.
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2007
According to WHO, there will be epidemic of diabetes world over and India is going to be 'A d... more According to WHO, there will be epidemic of diabetes world over and India is going to be 'A diabetes capital of the world' by 2025. With the increasing incidence of diabetes, the associated complications are also bound to increase. Rhinocerebral mucormycosis is one of them.Rhinocerebral Mucormycosis is an opportunistic, fulminating fungal infection, caused by Rhizopus species of order of mucorales, frequently seen in diabetic and immunocompromised patients. Mucormycosis has a very high mortality rate.Early diagnosis and treatment with Amphotericin-B is the key to combat this disease successfully. We have seen 13 cases in last 3 years (2002-2005) in our area. This incidence is significant, as this type of cases were rarely seen before 2002, in this geographical area. We present an account of these cases; treatment strategies adopted, review of literature, and highlight 'the role of ENT surgeon in diagnosis and management of this dreadful disease'.