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Rajeshwari Ravishankar

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Papers by Rajeshwari Ravishankar

Research paper thumbnail of Kimura Disease: A Rare Case of Parotid Swelling with Cervical Lymphadenopathy and a Review of Literature

International Journal of Medical Reviews and Case Reports

Kimura Disease (KD) is a rare chronic inflammatory disorder that involves the subcutaneous tissue... more Kimura Disease (KD) is a rare chronic inflammatory disorder that involves the subcutaneous tissues, occurring predominantly in the head and neck region, frequently associated with regional lymphadenopathy or salivary gland involvement. The etiology is largely unknown and it most commonly affects Asian men. KD is characterised by painless subcutaneous masses in the head and neck region, blood and tissue eosinophilia, and elevated immunoglobulin E (IgE)

Research paper thumbnail of Megakaryocytic alterations in thrombocytopenia: A bone marrow aspiration study

Indian Journal of Pathology and Microbiology, 2009

Background: Megakaryocyte morphology plays an important role in thrombopoiesis. A defect in any s... more Background: Megakaryocyte morphology plays an important role in thrombopoiesis. A defect in any stage of megakaryocytopoiesis can lead to dysmegakaryocytopoiesis and thrombocytopenia. This study was conducted to understand megakaryocytic alterations and their contribution in the diagnosis of cases of thrombocytopenia. Materials and methods: This was a cross-sectional study conducted on all consecutive cases of bone marrow aspirates of thrombocytopenia over a duration of one year in BPKIHS. Megakaryocyte morphology was studied with a 100X objective. Data were entered into Microsoft excel 10 and analysed with SPSS version 11.5. Descriptive statistics were charted and Chi-square tests were done for inferential statistics to find any association at 95% Confidence Interval.. Results: Among the 38 subjects, megakaryocytic thrombocytopenia (44.7%) was the most common cause of thrombocytopenia. Hypolobated megakaryocytes (63.2%), bare megakaryocytic nuclei (57.9%) were the common morphological changes in megakaryocytes. Odds of increased megakaryocyte count in megakaryocytic thrombocytopenia was found to be 12.5 times than for other causes of thrombocytopenia and the presence of bare megakaryocytic nuclei in Megakaryocytic Thrombocytopenia was statistically significant. (p-value<0.05) Conclusion: Many similarities were observed in megakaryocytic morphology among different hematological diseases. However, increased megakaryocyte count, and presence of bare megakaryocytic nuclei and hypolobated forms were significant in megakaryocytic thrombocytopenia.

Research paper thumbnail of Image-guided fine-needle aspiration cytology of deep-seated enlarged lymph nodes

Acta Radiologica, 2002

ABSTRACT

Research paper thumbnail of An intracerebral sporadic mixed cavernous angioma: An extremely rare entity with review of literature

Journal of Cerebrovascular Sciences

Research paper thumbnail of Kimura Disease: A Rare Case of Parotid Swelling with Cervical Lymphadenopathy and a Review of Literature

International Journal of Medical Reviews and Case Reports

Kimura Disease (KD) is a rare chronic inflammatory disorder that involves the subcutaneous tissue... more Kimura Disease (KD) is a rare chronic inflammatory disorder that involves the subcutaneous tissues, occurring predominantly in the head and neck region, frequently associated with regional lymphadenopathy or salivary gland involvement. The etiology is largely unknown and it most commonly affects Asian men. KD is characterised by painless subcutaneous masses in the head and neck region, blood and tissue eosinophilia, and elevated immunoglobulin E (IgE)

Research paper thumbnail of Megakaryocytic alterations in thrombocytopenia: A bone marrow aspiration study

Indian Journal of Pathology and Microbiology, 2009

Background: Megakaryocyte morphology plays an important role in thrombopoiesis. A defect in any s... more Background: Megakaryocyte morphology plays an important role in thrombopoiesis. A defect in any stage of megakaryocytopoiesis can lead to dysmegakaryocytopoiesis and thrombocytopenia. This study was conducted to understand megakaryocytic alterations and their contribution in the diagnosis of cases of thrombocytopenia. Materials and methods: This was a cross-sectional study conducted on all consecutive cases of bone marrow aspirates of thrombocytopenia over a duration of one year in BPKIHS. Megakaryocyte morphology was studied with a 100X objective. Data were entered into Microsoft excel 10 and analysed with SPSS version 11.5. Descriptive statistics were charted and Chi-square tests were done for inferential statistics to find any association at 95% Confidence Interval.. Results: Among the 38 subjects, megakaryocytic thrombocytopenia (44.7%) was the most common cause of thrombocytopenia. Hypolobated megakaryocytes (63.2%), bare megakaryocytic nuclei (57.9%) were the common morphological changes in megakaryocytes. Odds of increased megakaryocyte count in megakaryocytic thrombocytopenia was found to be 12.5 times than for other causes of thrombocytopenia and the presence of bare megakaryocytic nuclei in Megakaryocytic Thrombocytopenia was statistically significant. (p-value<0.05) Conclusion: Many similarities were observed in megakaryocytic morphology among different hematological diseases. However, increased megakaryocyte count, and presence of bare megakaryocytic nuclei and hypolobated forms were significant in megakaryocytic thrombocytopenia.

Research paper thumbnail of Image-guided fine-needle aspiration cytology of deep-seated enlarged lymph nodes

Acta Radiologica, 2002

ABSTRACT

Research paper thumbnail of An intracerebral sporadic mixed cavernous angioma: An extremely rare entity with review of literature

Journal of Cerebrovascular Sciences

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