Farnaz Ramezani - Academia.edu (original) (raw)
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Papers by Farnaz Ramezani
Neuromuscular Disorders, 2001
We report dizygotic twins who ®rst presented at the age of 6 months with severe diaphragmatic wea... more We report dizygotic twins who ®rst presented at the age of 6 months with severe diaphragmatic weakness and marked abnormalities of autonomic function. A female sibling had earlier died from a disorder with similar clinical features. Both twins had a severe axonal polyneuropathy with generalized hypotonic limb weakness together with diaphragmatic paralysis resulting in respiratory failure. Associated features were tachycardia, increased sweating, elevated body temperature, and hypertension, suggesting autonomic dysfunction. Nerve conduction studies indicated an axonopathy affecting both motor and sensory nerve ®bres. Sural nerve biopsy in one twin performed at the age of 7 months showed a reduced population of myelinated nerve ®bres, particularly those of larger diameter, with no indication of hypomyelination, demyelination or axonal atrophy. Examples of axonal forms of hereditary motor and sensory neuropathy (HMSN) with onset in infancy are very rare and autonomic involvement associated with this condition has not so far been described.
Background. Recurrent aphthous stomatitis (RAS) represents a very common oral lesion, affecting 5... more Background. Recurrent aphthous stomatitis (RAS) represents a very common oral lesion, affecting 5–60% of the general population. Different mechanisms might be involved in the etiopathogenesis of RAS, but to date, no single definite cause has been confirmed. Objectives. The aim of this study was to compare salivary epidermal growth factor (EGF) levels in two phases of RAS (ulcerative and remission phases) and in healthy controls. Material and Methods. In this case-control study, the salivary epidermal growth factor concentration (pg/mL) was measured in 18 consecutive dental patients with RAS compared to 18 healthy controls. The two groups were matched in terms of age, sex, and salivary flow rate. Unstimulated whole saliva samples were collected in the first 3 days after mucosal ulceration and two weeks after resolution of RAS and from healthy controls. Salivary epider-mal growth factor (SEGF) concentration was measured using the sandwich ELISA technique. Results. Saliva samples were ...
Neuromuscular Disorders, 2001
We report dizygotic twins who ®rst presented at the age of 6 months with severe diaphragmatic wea... more We report dizygotic twins who ®rst presented at the age of 6 months with severe diaphragmatic weakness and marked abnormalities of autonomic function. A female sibling had earlier died from a disorder with similar clinical features. Both twins had a severe axonal polyneuropathy with generalized hypotonic limb weakness together with diaphragmatic paralysis resulting in respiratory failure. Associated features were tachycardia, increased sweating, elevated body temperature, and hypertension, suggesting autonomic dysfunction. Nerve conduction studies indicated an axonopathy affecting both motor and sensory nerve ®bres. Sural nerve biopsy in one twin performed at the age of 7 months showed a reduced population of myelinated nerve ®bres, particularly those of larger diameter, with no indication of hypomyelination, demyelination or axonal atrophy. Examples of axonal forms of hereditary motor and sensory neuropathy (HMSN) with onset in infancy are very rare and autonomic involvement associated with this condition has not so far been described.
Background. Recurrent aphthous stomatitis (RAS) represents a very common oral lesion, affecting 5... more Background. Recurrent aphthous stomatitis (RAS) represents a very common oral lesion, affecting 5–60% of the general population. Different mechanisms might be involved in the etiopathogenesis of RAS, but to date, no single definite cause has been confirmed. Objectives. The aim of this study was to compare salivary epidermal growth factor (EGF) levels in two phases of RAS (ulcerative and remission phases) and in healthy controls. Material and Methods. In this case-control study, the salivary epidermal growth factor concentration (pg/mL) was measured in 18 consecutive dental patients with RAS compared to 18 healthy controls. The two groups were matched in terms of age, sex, and salivary flow rate. Unstimulated whole saliva samples were collected in the first 3 days after mucosal ulceration and two weeks after resolution of RAS and from healthy controls. Salivary epider-mal growth factor (SEGF) concentration was measured using the sandwich ELISA technique. Results. Saliva samples were ...