Raquel Bernardo - Academia.edu (original) (raw)

Papers by Raquel Bernardo

1 Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Depart... more 1 Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Biofísica e Biometria, Rio de Janeiro, RJ, Brasil. 2 Universidade do Grande Rio, Curso de Medicina, Duque de Caxias, RJ, Brasil. 3 Programa de Pós-Graduação em Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 4 Instituto Nacional de Câncer, Coordenadoria de Pesquisa, Rio de Janeiro, RJ, Brasil. 5 Faculdade de Medicina, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 6 Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil. 7 Universidade Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil.

Saúde (Santa Maria), 2015

O objetivo do presente estudo foi identificar o interesse científico, avaliando o número de publi... more O objetivo do presente estudo foi identificar o interesse científico, avaliando o número de publicações (NP) citadas por ano sobre exercício de vibração no corpo inteiro (EVCI) isolado e em associação a aplicações clínicas. A pesquisa foi realizada no PubMed, com a palavra-chave "whole body vibration" isolada ou em associação com doenças ou com envelhecimento. Foi demonstrado aumento crescente do interesse científico sobre EVCI nos últimos anos. Um elevado NP com as variáveis idoso e dor lombar foi identificado, indicando que as plataformas que possam gerar vibrações e os EVCI podem ser uma intervenção efetiva para o tratamento de alterações musculoesqueléticas em indivíduos treinados, não treinadas e idosos. Torna-se necessário ter atenção com aqueles que realizam EVCI em plataformas vibratórias devido as suas reações individuais, pois as informações científicas ainda são limitadas.

Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marke... more Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marked by progressive loss of nigrostriatal dopaminergic neurons which is related to a continuous impairment of motor functions. As pharmacological treatments (L-Dopa, Dopamin Agonists) are lowly effective with respect to postural disturbance, and furthermore they lose effectiveness with disease progression potent nonpharmacologic therapies, are of crucial importance for the management of impairments. Besides traditional types of exercise, like strength or endurance training, whole body vibration was found having positive influence on PD motor symptoms. The aim of this work is to present a suitable review about the published papers found in the PubMed in which there are information about the use of the whole body vibration in patients with PD. Using the keywords "Parkinson's disease" or "Parkinson's disease" associated with "whole body vibration" six publications were found. One publication among the six, it was about vibration delivered in the entire body produced by a physioacoustic chair and it was also not analyzed in this work. Five papers among six were selected after a search in the PubMed using the keywords "Parkinson´s disease" and "whole body vibration". The frequency used in four of these five papers is the same (6Hz). Only a paper presents a frequency of 25Hz. The positive findings indicated in the papers seem in depend on the frequency and they were found with 6 or 25 Hz. Only in a publication has not presented difference between the clinical conditions in the experimental (whole body vibration) and control (placebo). All the other authors have noticed positive clinical findings using the oscillating platform. It is highly relevant in the development of clinical procedures to the management of patients with PD. As the use of the oscillating platforms is very inexpensive and positive clinical findings have been noticed with the use of whole body vibration in patients with PD, it is suggested to implement the studies involving the application of the exercises with whole body vibration in oscillating platforms to manage the patients with PD.

Developmental neurorehabilitation, Jan 31, 2015

Whole body vibration (WBV) is increasingly being used to improve balance and motor function and r... more Whole body vibration (WBV) is increasingly being used to improve balance and motor function and reduce the secondary complications associated with cerebral palsy (CP). The purpose of this study was to systematically appraise published research regarding the effects of static and/or dynamic exercise performed on a vibrating platform on gait, strength, spasticity and bone mineral density (BMD) within this population. Systematic searches of six electronic databases identified five studies that met our inclusion criteria (2 at Level II and 3 at Level III-2). Studies were analysed to determine: (a) participant characteristics; (b) optimal exercise and WBV treatment protocol; (c) effect on gait, strength, spasticity and BMD; and (d) the outcome measures used to evaluate effect. As data was not homogenous a meta-analysis was not possible. Several design limitations were identified and intervention protocols are poorly described. The effects on strength, gait, spasticity and BMD in persons ...

Hepatobiliary & pancreatic diseases international : HBPD INT, 2010

Douglas described choledochal cysts in 1852 and Todani proposed an anatomy-based classification i... more Douglas described choledochal cysts in 1852 and Todani proposed an anatomy-based classification in 1977. The classification is the most extensively used, but does not include some rare variations. We present a case of hepatic duct diverticulum, one of the variations, and discuss its diagnosis and treatment. A 57-year-old woman presented with upper abdominal pain and discomfort associated with nausea and vomiting. She was finally diagnosed with cholelithiasis and right hepatic duct diverticulum. The patient underwent resection of the hepatic duct diverticulum and cholecystectomy, and was asymptomatic 26 months after surgery. Hepatic duct diverticulum is a rare form of choledochal cyst, not included in Todani's classification. Todani's classification including this and other uncommon variations of choledochal cysts must be reviewed. The best diagnostic imaging methods and treatment for choledochal cysts must be defined.

Brazilian Journal of Pharmacognosy, 2008

Journal of Zhejiang University SCIENCE B, 2006

Psidium guajava (guava) leaf is a phytotherapic used in folk medicine to treat gastrointestinal a... more Psidium guajava (guava) leaf is a phytotherapic used in folk medicine to treat gastrointestinal and respiratory disturbances and is used as anti-inflammatory medicine. In nuclear medicine, blood constituents (BC) are labelled with technetium-99m ( 99m Tc) and used to image procedures. However, data have demonstrated that synthetic or natural drugs could modify the labelling of BC with 99m Tc. The aim of this work was to evaluate the effects of aqueous extract of guava leaves on the labelling of BC with 99m Tc. Blood samples of Wistar rats were incubated with different concentrations of guava extract and labelled with 99m Tc after the percentage of incorporated radioactivity (%ATI) in BC was determined. The results suggest that aqueous guava extract could present antioxidant action and/or alters the membrane structures involved in ion transport into cells, thus decreasing the radiolabelling of BC with 99m Tc. The data showed significant (P<0.05) alteration of ATI in BC from blood incubated with guava extract.

Human Immunology, 2009

Aim: The KIR genes have been shown to be different in terms of gene and haplotypes frequencies de... more Aim: The KIR genes have been shown to be different in terms of gene and haplotypes frequencies depend on the population evaluated. The purpose of this study is to elucidate haplotypes patterns in Brazilian families of bone marrow receptors.

Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marke... more Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marked by progressive loss of nigrostriatal dopaminergic neurons which is related to a continuous impairment of motor functions. As pharmacological treatments (L-Dopa, Dopamin Agonists) are lowly effective with respect to postural disturbance, and furthermore they lose effectiveness with disease progression potent nonpharmacologic therapies, are of crucial importance for the management of impairments. Besides traditional types of exercise, like strength or endurance training, whole body vibration was found having positive influence on PD motor symptoms. The aim of this work is to present a suitable review about the published papers found in the PubMed in which there are information about the use of the whole body vibration in patients with PD. Using the keywords "Parkinson's disease" or "Parkinson's disease" associated with "whole body vibration" six publications were found. One publication among the six, it was about vibration delivered in the entire body produced by a physioacoustic chair and it was also not analyzed in this work. Five papers among six were selected after a search in the PubMed using the keywords "Parkinson´s disease" and "whole body vibration". The frequency used in four of these five papers is the same (6Hz). Only a paper presents a frequency of 25Hz. The positive findings indicated in the papers seem in depend on the frequency and they were found with 6 or 25 Hz. Only in a publication has not presented difference between the clinical conditions in the experimental (whole body vibration) and control (placebo). All the other authors have noticed positive clinical findings using the oscillating platform. It is highly relevant in the development of clinical procedures to the management of patients with PD. As the use of the oscillating platforms is very inexpensive and positive clinical findings have been noticed with the use of whole body vibration in patients with PD, it is suggested to implement the studies involving the application of the exercises with whole body vibration in oscillating platforms to manage the patients with PD.

The Chinese journal of physiology, Jan 31, 2015

There is a growing interest in the use of vibration generated by oscillating/vibratory platforms ... more There is a growing interest in the use of vibration generated by oscillating/vibratory platforms - also known as whole-body vibration (WBV) - for achieving therapeutic, preventative and/or physical performance goals. This study investigated the effects of vibration generated by an oscillating platform on the concentration of blood biomarkers in rats. Wistar rats (n = 8) were divided in 2 groups, sedated and individually positioned on an oscillating platform. The experimental group (EG) was subjected to vibrations of 20 Hz for one min per day for one week while the control group (CG) experienced no vibration. Samples of heparinized whole blood were drawn by cardiac puncture for biochemical analysis. Concentrations of total cholesterol, triglycerides, HDL, LDL, VLDL, glucose, CK, albumin, alkaline phosphates, TGP, TGO, γGT, lipase, amylase, urea and creatinine were determined. White blood cell count and a platelet hemogram were also performed. Following seven sessions of exposure to t...

1 Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Depart... more 1 Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Biofísica e Biometria, Rio de Janeiro, RJ, Brasil. 2 Universidade do Grande Rio, Curso de Medicina, Duque de Caxias, RJ, Brasil. 3 Programa de Pós-Graduação em Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 4 Instituto Nacional de Câncer, Coordenadoria de Pesquisa, Rio de Janeiro, RJ, Brasil. 5 Faculdade de Medicina, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. 6 Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil. 7 Universidade Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil.

Saúde (Santa Maria), 2015

O objetivo do presente estudo foi identificar o interesse científico, avaliando o número de publi... more O objetivo do presente estudo foi identificar o interesse científico, avaliando o número de publicações (NP) citadas por ano sobre exercício de vibração no corpo inteiro (EVCI) isolado e em associação a aplicações clínicas. A pesquisa foi realizada no PubMed, com a palavra-chave "whole body vibration" isolada ou em associação com doenças ou com envelhecimento. Foi demonstrado aumento crescente do interesse científico sobre EVCI nos últimos anos. Um elevado NP com as variáveis idoso e dor lombar foi identificado, indicando que as plataformas que possam gerar vibrações e os EVCI podem ser uma intervenção efetiva para o tratamento de alterações musculoesqueléticas em indivíduos treinados, não treinadas e idosos. Torna-se necessário ter atenção com aqueles que realizam EVCI em plataformas vibratórias devido as suas reações individuais, pois as informações científicas ainda são limitadas.

Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marke... more Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marked by progressive loss of nigrostriatal dopaminergic neurons which is related to a continuous impairment of motor functions. As pharmacological treatments (L-Dopa, Dopamin Agonists) are lowly effective with respect to postural disturbance, and furthermore they lose effectiveness with disease progression potent nonpharmacologic therapies, are of crucial importance for the management of impairments. Besides traditional types of exercise, like strength or endurance training, whole body vibration was found having positive influence on PD motor symptoms. The aim of this work is to present a suitable review about the published papers found in the PubMed in which there are information about the use of the whole body vibration in patients with PD. Using the keywords "Parkinson's disease" or "Parkinson's disease" associated with "whole body vibration" six publications were found. One publication among the six, it was about vibration delivered in the entire body produced by a physioacoustic chair and it was also not analyzed in this work. Five papers among six were selected after a search in the PubMed using the keywords "Parkinson´s disease" and "whole body vibration". The frequency used in four of these five papers is the same (6Hz). Only a paper presents a frequency of 25Hz. The positive findings indicated in the papers seem in depend on the frequency and they were found with 6 or 25 Hz. Only in a publication has not presented difference between the clinical conditions in the experimental (whole body vibration) and control (placebo). All the other authors have noticed positive clinical findings using the oscillating platform. It is highly relevant in the development of clinical procedures to the management of patients with PD. As the use of the oscillating platforms is very inexpensive and positive clinical findings have been noticed with the use of whole body vibration in patients with PD, it is suggested to implement the studies involving the application of the exercises with whole body vibration in oscillating platforms to manage the patients with PD.

Developmental neurorehabilitation, Jan 31, 2015

Whole body vibration (WBV) is increasingly being used to improve balance and motor function and r... more Whole body vibration (WBV) is increasingly being used to improve balance and motor function and reduce the secondary complications associated with cerebral palsy (CP). The purpose of this study was to systematically appraise published research regarding the effects of static and/or dynamic exercise performed on a vibrating platform on gait, strength, spasticity and bone mineral density (BMD) within this population. Systematic searches of six electronic databases identified five studies that met our inclusion criteria (2 at Level II and 3 at Level III-2). Studies were analysed to determine: (a) participant characteristics; (b) optimal exercise and WBV treatment protocol; (c) effect on gait, strength, spasticity and BMD; and (d) the outcome measures used to evaluate effect. As data was not homogenous a meta-analysis was not possible. Several design limitations were identified and intervention protocols are poorly described. The effects on strength, gait, spasticity and BMD in persons ...

Hepatobiliary & pancreatic diseases international : HBPD INT, 2010

Douglas described choledochal cysts in 1852 and Todani proposed an anatomy-based classification i... more Douglas described choledochal cysts in 1852 and Todani proposed an anatomy-based classification in 1977. The classification is the most extensively used, but does not include some rare variations. We present a case of hepatic duct diverticulum, one of the variations, and discuss its diagnosis and treatment. A 57-year-old woman presented with upper abdominal pain and discomfort associated with nausea and vomiting. She was finally diagnosed with cholelithiasis and right hepatic duct diverticulum. The patient underwent resection of the hepatic duct diverticulum and cholecystectomy, and was asymptomatic 26 months after surgery. Hepatic duct diverticulum is a rare form of choledochal cyst, not included in Todani's classification. Todani's classification including this and other uncommon variations of choledochal cysts must be reviewed. The best diagnostic imaging methods and treatment for choledochal cysts must be defined.

Brazilian Journal of Pharmacognosy, 2008

Journal of Zhejiang University SCIENCE B, 2006

Psidium guajava (guava) leaf is a phytotherapic used in folk medicine to treat gastrointestinal a... more Psidium guajava (guava) leaf is a phytotherapic used in folk medicine to treat gastrointestinal and respiratory disturbances and is used as anti-inflammatory medicine. In nuclear medicine, blood constituents (BC) are labelled with technetium-99m ( 99m Tc) and used to image procedures. However, data have demonstrated that synthetic or natural drugs could modify the labelling of BC with 99m Tc. The aim of this work was to evaluate the effects of aqueous extract of guava leaves on the labelling of BC with 99m Tc. Blood samples of Wistar rats were incubated with different concentrations of guava extract and labelled with 99m Tc after the percentage of incorporated radioactivity (%ATI) in BC was determined. The results suggest that aqueous guava extract could present antioxidant action and/or alters the membrane structures involved in ion transport into cells, thus decreasing the radiolabelling of BC with 99m Tc. The data showed significant (P<0.05) alteration of ATI in BC from blood incubated with guava extract.

Human Immunology, 2009

Aim: The KIR genes have been shown to be different in terms of gene and haplotypes frequencies de... more Aim: The KIR genes have been shown to be different in terms of gene and haplotypes frequencies depend on the population evaluated. The purpose of this study is to elucidate haplotypes patterns in Brazilian families of bone marrow receptors.

Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marke... more Parkinson's disease (PD) is a complex, progressive and disabling neurodegenerative disorder marked by progressive loss of nigrostriatal dopaminergic neurons which is related to a continuous impairment of motor functions. As pharmacological treatments (L-Dopa, Dopamin Agonists) are lowly effective with respect to postural disturbance, and furthermore they lose effectiveness with disease progression potent nonpharmacologic therapies, are of crucial importance for the management of impairments. Besides traditional types of exercise, like strength or endurance training, whole body vibration was found having positive influence on PD motor symptoms. The aim of this work is to present a suitable review about the published papers found in the PubMed in which there are information about the use of the whole body vibration in patients with PD. Using the keywords "Parkinson's disease" or "Parkinson's disease" associated with "whole body vibration" six publications were found. One publication among the six, it was about vibration delivered in the entire body produced by a physioacoustic chair and it was also not analyzed in this work. Five papers among six were selected after a search in the PubMed using the keywords "Parkinson´s disease" and "whole body vibration". The frequency used in four of these five papers is the same (6Hz). Only a paper presents a frequency of 25Hz. The positive findings indicated in the papers seem in depend on the frequency and they were found with 6 or 25 Hz. Only in a publication has not presented difference between the clinical conditions in the experimental (whole body vibration) and control (placebo). All the other authors have noticed positive clinical findings using the oscillating platform. It is highly relevant in the development of clinical procedures to the management of patients with PD. As the use of the oscillating platforms is very inexpensive and positive clinical findings have been noticed with the use of whole body vibration in patients with PD, it is suggested to implement the studies involving the application of the exercises with whole body vibration in oscillating platforms to manage the patients with PD.

The Chinese journal of physiology, Jan 31, 2015

There is a growing interest in the use of vibration generated by oscillating/vibratory platforms ... more There is a growing interest in the use of vibration generated by oscillating/vibratory platforms - also known as whole-body vibration (WBV) - for achieving therapeutic, preventative and/or physical performance goals. This study investigated the effects of vibration generated by an oscillating platform on the concentration of blood biomarkers in rats. Wistar rats (n = 8) were divided in 2 groups, sedated and individually positioned on an oscillating platform. The experimental group (EG) was subjected to vibrations of 20 Hz for one min per day for one week while the control group (CG) experienced no vibration. Samples of heparinized whole blood were drawn by cardiac puncture for biochemical analysis. Concentrations of total cholesterol, triglycerides, HDL, LDL, VLDL, glucose, CK, albumin, alkaline phosphates, TGP, TGO, γGT, lipase, amylase, urea and creatinine were determined. White blood cell count and a platelet hemogram were also performed. Following seven sessions of exposure to t...