Ray Harvey - Academia.edu (original) (raw)

Papers by Ray Harvey

Research paper thumbnail of Over-the-Counter Decorative Contact Lenses: Cosmetic or Medical Devices? A Case Series

Eye & Contact Lens: Science & Clinical Practice, 2005

To illustrate the implications of the unauthorized sale and unmonitored wearing of decorative cos... more To illustrate the implications of the unauthorized sale and unmonitored wearing of decorative cosmetic contact lenses resulting in ocular complications and to determine the prevalence of the use of cosmetic contact lenses obtained from unlicensed providers by adolescents. Observational case report, structured interview, and survey in a retrospective, observational, clinical practice setting. Reported sources of contact lenses were categorized as provider and nonprovider, and associations within the data were reviewed by using a Pearson correlation and chi-square test. Twelve patients (eight female and four male) were seen urgently for acute eye pain and redness after wearing plano decorative contact lenses. None of the patients had previously worn a contact lens. None of the lenses were dispensed by eye care professionals. Four patients developed blinding infections requiring hospital admission. Causative organisms included staphylococci, Pseudomonas, and acanthamoeba. One patient required a penetrating keratoplasty. One hundred fifty-nine patients were surveyed. Thirty-seven (23%) used decorative contact lenses. Lenses were obtained from an unlicensed provider 51% of the time. Education about lens care and handling was significantly associated with acquiring lenses from licensed providers (R = 0.74, P < 0.0001). Colored noncorrective contact lenses are being dispensed without a prescription or fitting from unlicensed vendors. Patients who acquire lenses from unauthorized providers are significantly less likely to be instructed on appropriate lens use and care. Consequently, uninformed lens wearers are experiencing acute vision-threatening infections and inflammation.

Research paper thumbnail of Prospective analysis of weight changes in adolescent females initiating depot medroxyprogesterone acetate (DMPA), oral contraceptive pills (OC), or no hormonal contraceptive method

Journal of Adolescent Health, 2003

Journal of Adolescent Health, Volume 32, Issue 2, Pages 134, February 2003, Authors:Andrea Bonny,... more Journal of Adolescent Health, Volume 32, Issue 2, Pages 134, February 2003, Authors:Andrea Bonny, MD; Kelly Camlin; Ray Harvey, BS; KM Islam, MD; Sara Debanne, Ph.D.; Barbara Cromer, MD. ...

Research paper thumbnail of Bone markers in adolescent girls on depot medroxyprogesterone acetate and ultra-low-dose oral contraceptives

Journal of Adolescent Health, 2004

detection of ASCUS and LSIL. Although agreement between SC and CC samples was also only moderate ... more detection of ASCUS and LSIL. Although agreement between SC and CC samples was also only moderate for those with HR and LR types, there is no gold standard by which to determine which collection method is more accurate. Future studies will help to define this gold standard and clarify the role of HPV DNA self-testing in screening and management of adolescents.

Research paper thumbnail of Reference values for bone mineral density in 12- to 18-year-old girls categorized by weight, race, and age

Pediatric Radiology, 2004

Background: Normative bone mineral density (BMD) values for adults do not apply to the pediatric ... more Background: Normative bone mineral density (BMD) values for adults do not apply to the pediatric population because of dramatic and variable rates of bone mineral acquisition that take place throughout adolescence. Objective: This study was designed to provide normative BMD values for the lumbar spine and femoral neck by age, weight, and race in female adolescents for use by clinicians. Materials and methods: The study population comprised 422 healthy adolescent girls aged 12–18 years recruited from four primary-care clinics. BMD measurements were performed with dual-energy X-ray absorptiometry (DEXA). Results: The major statistical predictors of lumbar spine BMD and femoral neck BMD were race, chronological age, and weight. There was an increase in both lumbar spine and femoral neck BMD that paralleled an increase in age and weight. In addition, the lumbar spine BMD and the femoral neck BMD were higher in the black participants than in the non-black participants with mean BMD values in grams per centimeter squared of 1.02 and 0.98, respectively, for blacks and 0.96 and 0.89, respectively, for non-blacks (P<0.001). Conclusion: Our study produced the largest set of lumbar spine and femoral neck BMD normative values for female adolescents and confirms the importance of both demographic and anthropomorphic variables in determining normative BMD values.

Research paper thumbnail of Weight Gain in Obese and Nonobese Adolescent Girls Initiating Depot Medroxyprogesterone, Oral Contraceptive Pills, or No Hormonal Contraceptive Method

To examine weight changes in a large cohort of obese and nonobese adolescent girls initiating dep... more To examine weight changes in a large cohort of obese and nonobese adolescent girls initiating depot medroxyprogesterone acetate (DMPA), an oral contraceptive (OC), or no hormonal contraceptive method (control). Prospective study of 450 adolescent girls, aged 12 to 18 years, who attended 4 urban health clinics and selected DMPA, OC, or control. Data collection occurred at baseline and at 6, 12, and 18 months; consisted of structured interview and measurement of height and weight; and occurred from April 19, 2000, through September 26, 2003. Weight was examined as mean change over 18 months and actual weight at each study visit. On the basis of preliminary analyses, we stratified the sample according to baseline obesity status (nonobese, body mass index [calculated as weight in kilograms divided by the square of height in meters] &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 30; obese, body mass index &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; or =30). Adolescent girls who were obese at initiation of DMPA gained significantly more weight than did obese girls starting OC or control (P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001 for both). At 18 months, mean weight gain was 9.4, 0.2, and 3.1 kg for obese girls receiving DMPA, receiving OC, and control, respectively. Weight gain in obese girls receiving DMPA was also greater than weight gain in all nonobese categories (4.0 kg, DMPA; 2.8 kg, OC; 3.5 kg, control; P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001). A significant interaction (P = .006) between length of time receiving DMPA and weight gain was evident for obese subjects. Over 18 months, DMPA use was associated with increasing rates of weight gain in obese subjects. The potential contribution to severe obesity in this population is concerning.

Research paper thumbnail of Over-the-Counter Decorative Contact Lenses: Cosmetic or Medical Devices? A Case Series

Eye & Contact Lens: Science & Clinical Practice, 2005

To illustrate the implications of the unauthorized sale and unmonitored wearing of decorative cos... more To illustrate the implications of the unauthorized sale and unmonitored wearing of decorative cosmetic contact lenses resulting in ocular complications and to determine the prevalence of the use of cosmetic contact lenses obtained from unlicensed providers by adolescents. Observational case report, structured interview, and survey in a retrospective, observational, clinical practice setting. Reported sources of contact lenses were categorized as provider and nonprovider, and associations within the data were reviewed by using a Pearson correlation and chi-square test. Twelve patients (eight female and four male) were seen urgently for acute eye pain and redness after wearing plano decorative contact lenses. None of the patients had previously worn a contact lens. None of the lenses were dispensed by eye care professionals. Four patients developed blinding infections requiring hospital admission. Causative organisms included staphylococci, Pseudomonas, and acanthamoeba. One patient required a penetrating keratoplasty. One hundred fifty-nine patients were surveyed. Thirty-seven (23%) used decorative contact lenses. Lenses were obtained from an unlicensed provider 51% of the time. Education about lens care and handling was significantly associated with acquiring lenses from licensed providers (R = 0.74, P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.0001). Colored noncorrective contact lenses are being dispensed without a prescription or fitting from unlicensed vendors. Patients who acquire lenses from unauthorized providers are significantly less likely to be instructed on appropriate lens use and care. Consequently, uninformed lens wearers are experiencing acute vision-threatening infections and inflammation.

Research paper thumbnail of Prospective analysis of weight changes in adolescent females initiating depot medroxyprogesterone acetate (DMPA), oral contraceptive pills (OC), or no hormonal contraceptive method

Journal of Adolescent Health, 2003

Journal of Adolescent Health, Volume 32, Issue 2, Pages 134, February 2003, Authors:Andrea Bonny,... more Journal of Adolescent Health, Volume 32, Issue 2, Pages 134, February 2003, Authors:Andrea Bonny, MD; Kelly Camlin; Ray Harvey, BS; KM Islam, MD; Sara Debanne, Ph.D.; Barbara Cromer, MD. ...

Research paper thumbnail of Bone markers in adolescent girls on depot medroxyprogesterone acetate and ultra-low-dose oral contraceptives

Journal of Adolescent Health, 2004

detection of ASCUS and LSIL. Although agreement between SC and CC samples was also only moderate ... more detection of ASCUS and LSIL. Although agreement between SC and CC samples was also only moderate for those with HR and LR types, there is no gold standard by which to determine which collection method is more accurate. Future studies will help to define this gold standard and clarify the role of HPV DNA self-testing in screening and management of adolescents.

Research paper thumbnail of Reference values for bone mineral density in 12- to 18-year-old girls categorized by weight, race, and age

Pediatric Radiology, 2004

Background: Normative bone mineral density (BMD) values for adults do not apply to the pediatric ... more Background: Normative bone mineral density (BMD) values for adults do not apply to the pediatric population because of dramatic and variable rates of bone mineral acquisition that take place throughout adolescence. Objective: This study was designed to provide normative BMD values for the lumbar spine and femoral neck by age, weight, and race in female adolescents for use by clinicians. Materials and methods: The study population comprised 422 healthy adolescent girls aged 12–18 years recruited from four primary-care clinics. BMD measurements were performed with dual-energy X-ray absorptiometry (DEXA). Results: The major statistical predictors of lumbar spine BMD and femoral neck BMD were race, chronological age, and weight. There was an increase in both lumbar spine and femoral neck BMD that paralleled an increase in age and weight. In addition, the lumbar spine BMD and the femoral neck BMD were higher in the black participants than in the non-black participants with mean BMD values in grams per centimeter squared of 1.02 and 0.98, respectively, for blacks and 0.96 and 0.89, respectively, for non-blacks (P<0.001). Conclusion: Our study produced the largest set of lumbar spine and femoral neck BMD normative values for female adolescents and confirms the importance of both demographic and anthropomorphic variables in determining normative BMD values.

Research paper thumbnail of Weight Gain in Obese and Nonobese Adolescent Girls Initiating Depot Medroxyprogesterone, Oral Contraceptive Pills, or No Hormonal Contraceptive Method

To examine weight changes in a large cohort of obese and nonobese adolescent girls initiating dep... more To examine weight changes in a large cohort of obese and nonobese adolescent girls initiating depot medroxyprogesterone acetate (DMPA), an oral contraceptive (OC), or no hormonal contraceptive method (control). Prospective study of 450 adolescent girls, aged 12 to 18 years, who attended 4 urban health clinics and selected DMPA, OC, or control. Data collection occurred at baseline and at 6, 12, and 18 months; consisted of structured interview and measurement of height and weight; and occurred from April 19, 2000, through September 26, 2003. Weight was examined as mean change over 18 months and actual weight at each study visit. On the basis of preliminary analyses, we stratified the sample according to baseline obesity status (nonobese, body mass index [calculated as weight in kilograms divided by the square of height in meters] &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 30; obese, body mass index &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; or =30). Adolescent girls who were obese at initiation of DMPA gained significantly more weight than did obese girls starting OC or control (P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001 for both). At 18 months, mean weight gain was 9.4, 0.2, and 3.1 kg for obese girls receiving DMPA, receiving OC, and control, respectively. Weight gain in obese girls receiving DMPA was also greater than weight gain in all nonobese categories (4.0 kg, DMPA; 2.8 kg, OC; 3.5 kg, control; P&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;.001). A significant interaction (P = .006) between length of time receiving DMPA and weight gain was evident for obese subjects. Over 18 months, DMPA use was associated with increasing rates of weight gain in obese subjects. The potential contribution to severe obesity in this population is concerning.