Rea Mae Soriano - Academia.edu (original) (raw)
Papers by Rea Mae Soriano
Transplantation Proceedings, 1998
Transplantation Proceedings, 1999
American Journal of Alternative Agriculture, 2001
A case study of the nopal-vegetable agroecosystem in metropolitan Mexico City was conducted to ev... more A case study of the nopal-vegetable agroecosystem in metropolitan Mexico City was conducted to evaluate the crop's economic productivity and sustainability using economic, social, and environmental indicators. Economic indicators were based on a gross margin analysis, commercialization strategies, and provision of employment. Social indicators were education level, family size, origin of laborers, plot size providing a measure of equity, and social self-organization. Environmental indicators were soil nutrient content and fertilizer application, technological management, and crop and natural biodiversity. Information on relevant social, technological, and economic elements was obtained through structured interviews with 100 producers of the city's nopalproducing zone of Milpa Alta in the hills southeast of Mexico City. Analysis of soil samples from cropped fields at three different depths was conducted, along with a study of nopal-associated weed species used by the communit...
ugr.es
... José Jesús Martín Martín M. Puerto López del Amo González Mariano Sánchez Martínez Rosa M. So... more ... José Jesús Martín Martín M. Puerto López del Amo González Mariano Sánchez Martínez Rosa M. Soriano ... Martin JJ y López del Amo MP (2011 ... http://publications.iom.int/bookstore/index.php? main_page=product_info&products_id=655&language=es • O'Rourke, Kevin H., and ...
HIV Medicine, 2013
The aims of the study were to describe the sociodemographic profile of men who have sex with men ... more The aims of the study were to describe the sociodemographic profile of men who have sex with men (MSM) who have never been tested for HIV and to analyse factors associated with never having been tested. Methods The European MSM Internet Survey (EMIS) was implemented in 2010 in 38 European countries on websites for MSM and collected data on sociodemographics, sexual behaviour, and other sexual health variables. A logistic regression analysis was conducted to assess variables associated with never having been tested for HIV. Results Of the 13 111 respondents living in Spain, 26% had never been tested for HIV. Those who had never been tested were significantly more likely to live in a settlement with fewer than 100 000 inhabitants, be younger than 25 years old, have a lower education level, be a student, and identify themselves as bisexual. In the multivariate analysis, to have never been tested for HIV was associated with being born in Spain [odds ratio (OR) 1.35; 95% confidence interval (CI) 1.192-1.539], living outside large settlements (OR 1.37; 95% CI 1.216-1.534), being younger than 25 years old (OR 2.94; 95% CI 2.510-3.441), being out to no one or only a few people (OR 2.16; 95% CI 1.938-2.399), having had no nonsteady partners in the last 12 months (OR 1.26; 95% CI 1.109-1.422), and being not at all confident to access HIV testing (OR 3.66; 95% CI 2.676-5.003), among others factors. Conclusions The profile of the MSM who had never been tested for HIV indicates that most of them were men who were hard to reach (young, bisexual men, in the closet). Interventions should aim to improve access to and the convenience of testing.
Experimental Cell Research, 1971
TESIS DOCTORAL NUEVAS FORMAS DE ORGANIZACIÓN FAMILIAR: MATRIMONIOS A DISTANCIA DOCTORANDO Mª ROSA... more TESIS DOCTORAL NUEVAS FORMAS DE ORGANIZACIÓN FAMILIAR: MATRIMONIOS A DISTANCIA DOCTORANDO Mª ROSA RODRIGO SORIANO DIRECTOR JULIO IGLESIAS DE USSEL Y ORDIS _____ PROGRAMA PROBLEMAS DE LA SOCIEDAD ...
…, 2007
Mice have been used extensively for studying normal prostate development and for generation of tr... more Mice have been used extensively for studying normal prostate development and for generation of transgenic or knock-out prostate cancer animal models. To understand systematically and thoroughly the androgen responsive program in the mouse prostate, we carried out microarray analysis to profile gene expression changes during prostate involution and re-growth triggered by castration and subsequent hormone replacement. Genes with significant changes in these two processes were identified and gene ontology analyses revealed that they were mainly involved in response mechanisms, cell adhesion, metabolism, protein metabolism, and cell-cycle progression. The changes observed during prostate involution were largely reversed during re-growth. Sixty-four genes, including Nkx3.1 and probasin, and 65 other genes, including insulin-like growth factor binding protein 3 and H-cadherin (H-Cad), were further identified respectively as androgen-responsive genes and genes inversely correlated with androgen, based on their down- or up-regulation following castration and up- or down-regulation following androgen replacement. Potential androgen-responsive elements were found in the 5' upstream promoter region of 47 of those 65 genes, suggesting a potential suppression mechanism by androgen receptor. Of these, the role of H-Cad in tumorigenesis was further evaluated. Reduction of H-Cad transcript level was found in the majority of human prostate cancer cell lines and prostatic adenocarcinoma samples examined. Furthermore, induced H-Cad expression in DU145 cells, and knock-down of H-Cad expression in BPH1 cells inhibited and facilitated tumorigenicity, respectively. Taken together, our study provides a molecular understanding of the mouse prostate involution and re-growth processes and identifies a set of genes that are inversely correlated with androgen and may be potentially suppressive for tumorigenesis.
Cities, 2000
This paper examines the use of urban space by dairy production activities in two areas of Mexico ... more This paper examines the use of urban space by dairy production activities in two areas of Mexico City with different degrees of urbanization (east and south). These activities have adapted to the recent urban conditions, from an original rural state. Dairy production is carried out in the house area, and producers pay for urban services as other residents. In the
Cancer Research, 2009
Abstract #2057 Purpose: Bone metastases are commonly observed in patients with advanced breast ca... more Abstract #2057 Purpose: Bone metastases are commonly observed in patients with advanced breast cancer. Tumor cells interact with the bone microenvironment to induce osteoclastogenesis via local bone stromal expression of receptor activator of NF-kB ligand (RANKL), leading to bone destruction and release of growth factors. In addition to its critical role in tumor-induced osteolysis, RANKL has been demonstrated to enhance the invasive behavior of epithelial tumor cells that express RANK, and RANK over-expression in transgenic mice using the breast-specific MMTV promoter results in increased mammary carcinoma. This study assessed the expression of human RANK and its ligand (RANKL) in invasive ductal carcinoma (IDC). Methods: We studied a total of 57 IDC specimens. Antibodies against human RANK (AF683) and human RANKL (M366; Amgen) were used for immunohistochemistry (IHC) cell staining along with an isotype control. The specificity of the 2 antibodies was substantiated by IHC, flow cytometry and Western blot analysis of positive and negative control cells. In addition, for RANK, mass spectrometry/protein sequencing of immunoprecipitated proteins was performed. The intensity of IHC staining was scored on a semiquantitative scale (1=weak, 2=moderate, 3=intense) or a complex scale (sum of percentages of stained tumor cells x staining intensity (0-3)). Results: Using a complex score with a threshold of 10, 20/57 IDC (35%) expressed minimal level of RANK (range 0 to Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 2057.
Cancer, 1977
The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compa... more The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.
Bone, 2011
the number and size of osteolytic lesions by ex-vivo μCT (p < 0.05) and X-ray (p < 0.05). Thus, H... more the number and size of osteolytic lesions by ex-vivo μCT (p < 0.05) and X-ray (p < 0.05). Thus, Hh-independent regulation of Gli2 inhibition in vivo may be a therapeutic target for breast cancer bone metastases. Conflict of interest statement: None declared.
Oncogene, 2007
Tumor cells with stem cell-like properties can be cultured from human glioblastomas by using cond... more Tumor cells with stem cell-like properties can be cultured from human glioblastomas by using conditions that select for the expansion of neural stem cells. We generated cell lines from glioblastoma specimens with the goal to obtain model systems for glioma stem cell biology. Unsupervised analysis of the expression profiles of nine cell lines established under neural stem cell conditions yielded two distinct clusters. Four cell lines were characterized by the expression of neurodevelopmental genes. They showed a multipotent differentiation profile along neuronal, astroglial and oligodendroglial lineages, grew spherically in vitro, expressed CD133 and formed highly invasive tumors in vivo. The other five cell lines shared expression signatures enriched for extracellular matrix-related genes, had a more restricted differentiation capacity, contained no or fewer CD133 þ cells, grew semiadherent or adherent in vitro and displayed reduced tumorigenicity and invasion in vivo. Our findings show that stable, multipotent glioblastoma cell lines with a full stem-like phenotype express neurodevelopmental genes as a distinctive feature, which may offer therapeutic targeting opportunities. The generation of another distinct cluster of cell lines showing similarly homogeneous profiling but restricted stem cell properties suggests that different phenotypes exist, each of which may lead to the typical appearance of glioblastoma.
Modelización …, 2008
Boluda-Botella N., Cases V., Gomis V., León VM, and Soriano R. ... Chemical Engineering Departmen... more Boluda-Botella N., Cases V., Gomis V., León VM, and Soriano R. ... Chemical Engineering Department, University of Alicante. Apdo. 99, E-03080 Alicante (Spain). Tel.+34 965903400, ext.2647. Fax:+34 965903826. ... LAS Standard: 12.1% C LAS, 34.1% C LAS, 30.6% C ...
alliancefordonation.org
... Ashley E. Anker, MA Department of Communication University at Buffalo, The State University o... more ... Ashley E. Anker, MA Department of Communication University at Buffalo, The State University of New York Buffalo, New York, USA ... Tera Kane, BA Department of Communication University at Buffalo, The State University of New York Buffalo, New York, USA ...
Geriatric Nursing, 1994
In a survey of directors of nursing services of 101 nursing homes, it was found that 17 homes sti... more In a survey of directors of nursing services of 101 nursing homes, it was found that 17 homes still used syringes to feed some of their frail residents. Three of these 17 facilities did not have easy access to speech pathologists, and the facility feeding the greatest number of residents by syringe did not use the services of a speech pathologist to assess swallowing. The practice of syringe feeding seems to be going out of favor, but until this practice is no longer used it is hoped that the recommendations in this article will increase the knowledge and awareness of professional nurses, who are often instrumental in coordinating the difficult and complex decision to syringe feed.
Purification of high added value products obtained by fermentation processes is a key research ta... more Purification of high added value products obtained by fermentation processes is a key research task in current biotechnology, especially the ones concerning proteins of very similar molecular structure such as isoenzymes. Purification and separation of biomolecules by commercial ion exchangers is an attractive alternative to affinity chromatography due to its availability and lower cost. For this reason and for its
... Soriano, R., Bautista, LF, Martínez, M. and Aracil, J. (1999), Adsorption isotherms of the As... more ... Soriano, R., Bautista, LF, Martínez, M. and Aracil, J. (1999), Adsorption isotherms of the Aspergillus niger glucoamylases I and II on the ... named glucoamylase I and glucoamylase II) on the resin DEAE–Toyopearl 650 are presented and fitted to the Langmuir model and Henry's ...
Transplantation Proceedings, 1998
Transplantation Proceedings, 1999
American Journal of Alternative Agriculture, 2001
A case study of the nopal-vegetable agroecosystem in metropolitan Mexico City was conducted to ev... more A case study of the nopal-vegetable agroecosystem in metropolitan Mexico City was conducted to evaluate the crop's economic productivity and sustainability using economic, social, and environmental indicators. Economic indicators were based on a gross margin analysis, commercialization strategies, and provision of employment. Social indicators were education level, family size, origin of laborers, plot size providing a measure of equity, and social self-organization. Environmental indicators were soil nutrient content and fertilizer application, technological management, and crop and natural biodiversity. Information on relevant social, technological, and economic elements was obtained through structured interviews with 100 producers of the city's nopalproducing zone of Milpa Alta in the hills southeast of Mexico City. Analysis of soil samples from cropped fields at three different depths was conducted, along with a study of nopal-associated weed species used by the communit...
ugr.es
... José Jesús Martín Martín M. Puerto López del Amo González Mariano Sánchez Martínez Rosa M. So... more ... José Jesús Martín Martín M. Puerto López del Amo González Mariano Sánchez Martínez Rosa M. Soriano ... Martin JJ y López del Amo MP (2011 ... http://publications.iom.int/bookstore/index.php? main_page=product_info&products_id=655&language=es • O'Rourke, Kevin H., and ...
HIV Medicine, 2013
The aims of the study were to describe the sociodemographic profile of men who have sex with men ... more The aims of the study were to describe the sociodemographic profile of men who have sex with men (MSM) who have never been tested for HIV and to analyse factors associated with never having been tested. Methods The European MSM Internet Survey (EMIS) was implemented in 2010 in 38 European countries on websites for MSM and collected data on sociodemographics, sexual behaviour, and other sexual health variables. A logistic regression analysis was conducted to assess variables associated with never having been tested for HIV. Results Of the 13 111 respondents living in Spain, 26% had never been tested for HIV. Those who had never been tested were significantly more likely to live in a settlement with fewer than 100 000 inhabitants, be younger than 25 years old, have a lower education level, be a student, and identify themselves as bisexual. In the multivariate analysis, to have never been tested for HIV was associated with being born in Spain [odds ratio (OR) 1.35; 95% confidence interval (CI) 1.192-1.539], living outside large settlements (OR 1.37; 95% CI 1.216-1.534), being younger than 25 years old (OR 2.94; 95% CI 2.510-3.441), being out to no one or only a few people (OR 2.16; 95% CI 1.938-2.399), having had no nonsteady partners in the last 12 months (OR 1.26; 95% CI 1.109-1.422), and being not at all confident to access HIV testing (OR 3.66; 95% CI 2.676-5.003), among others factors. Conclusions The profile of the MSM who had never been tested for HIV indicates that most of them were men who were hard to reach (young, bisexual men, in the closet). Interventions should aim to improve access to and the convenience of testing.
Experimental Cell Research, 1971
TESIS DOCTORAL NUEVAS FORMAS DE ORGANIZACIÓN FAMILIAR: MATRIMONIOS A DISTANCIA DOCTORANDO Mª ROSA... more TESIS DOCTORAL NUEVAS FORMAS DE ORGANIZACIÓN FAMILIAR: MATRIMONIOS A DISTANCIA DOCTORANDO Mª ROSA RODRIGO SORIANO DIRECTOR JULIO IGLESIAS DE USSEL Y ORDIS _____ PROGRAMA PROBLEMAS DE LA SOCIEDAD ...
…, 2007
Mice have been used extensively for studying normal prostate development and for generation of tr... more Mice have been used extensively for studying normal prostate development and for generation of transgenic or knock-out prostate cancer animal models. To understand systematically and thoroughly the androgen responsive program in the mouse prostate, we carried out microarray analysis to profile gene expression changes during prostate involution and re-growth triggered by castration and subsequent hormone replacement. Genes with significant changes in these two processes were identified and gene ontology analyses revealed that they were mainly involved in response mechanisms, cell adhesion, metabolism, protein metabolism, and cell-cycle progression. The changes observed during prostate involution were largely reversed during re-growth. Sixty-four genes, including Nkx3.1 and probasin, and 65 other genes, including insulin-like growth factor binding protein 3 and H-cadherin (H-Cad), were further identified respectively as androgen-responsive genes and genes inversely correlated with androgen, based on their down- or up-regulation following castration and up- or down-regulation following androgen replacement. Potential androgen-responsive elements were found in the 5&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; upstream promoter region of 47 of those 65 genes, suggesting a potential suppression mechanism by androgen receptor. Of these, the role of H-Cad in tumorigenesis was further evaluated. Reduction of H-Cad transcript level was found in the majority of human prostate cancer cell lines and prostatic adenocarcinoma samples examined. Furthermore, induced H-Cad expression in DU145 cells, and knock-down of H-Cad expression in BPH1 cells inhibited and facilitated tumorigenicity, respectively. Taken together, our study provides a molecular understanding of the mouse prostate involution and re-growth processes and identifies a set of genes that are inversely correlated with androgen and may be potentially suppressive for tumorigenesis.
Cities, 2000
This paper examines the use of urban space by dairy production activities in two areas of Mexico ... more This paper examines the use of urban space by dairy production activities in two areas of Mexico City with different degrees of urbanization (east and south). These activities have adapted to the recent urban conditions, from an original rural state. Dairy production is carried out in the house area, and producers pay for urban services as other residents. In the
Cancer Research, 2009
Abstract #2057 Purpose: Bone metastases are commonly observed in patients with advanced breast ca... more Abstract #2057 Purpose: Bone metastases are commonly observed in patients with advanced breast cancer. Tumor cells interact with the bone microenvironment to induce osteoclastogenesis via local bone stromal expression of receptor activator of NF-kB ligand (RANKL), leading to bone destruction and release of growth factors. In addition to its critical role in tumor-induced osteolysis, RANKL has been demonstrated to enhance the invasive behavior of epithelial tumor cells that express RANK, and RANK over-expression in transgenic mice using the breast-specific MMTV promoter results in increased mammary carcinoma. This study assessed the expression of human RANK and its ligand (RANKL) in invasive ductal carcinoma (IDC). Methods: We studied a total of 57 IDC specimens. Antibodies against human RANK (AF683) and human RANKL (M366; Amgen) were used for immunohistochemistry (IHC) cell staining along with an isotype control. The specificity of the 2 antibodies was substantiated by IHC, flow cytometry and Western blot analysis of positive and negative control cells. In addition, for RANK, mass spectrometry/protein sequencing of immunoprecipitated proteins was performed. The intensity of IHC staining was scored on a semiquantitative scale (1=weak, 2=moderate, 3=intense) or a complex scale (sum of percentages of stained tumor cells x staining intensity (0-3)). Results: Using a complex score with a threshold of 10, 20/57 IDC (35%) expressed minimal level of RANK (range 0 to Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 2057.
Cancer, 1977
The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compa... more The ultrastructure of nodular synovitis of the knee and epithelioid sarcoma of the hand are compared. Both lesions show a similar pattern of light and dark cells having filopodia and microvilli, an outer coat of finely granular matrix without well defined basal laminae, maculae adherentes and attachment sites, pinocytotic vesicles, cytoplasmic filaments and complex nuclear invaginations. These similarities suggest a common histogenesis and support the concept that the epithelioid sarcoma is derived from synovioblastic mesenchyme.
Bone, 2011
the number and size of osteolytic lesions by ex-vivo μCT (p < 0.05) and X-ray (p < 0.05). Thus, H... more the number and size of osteolytic lesions by ex-vivo μCT (p < 0.05) and X-ray (p < 0.05). Thus, Hh-independent regulation of Gli2 inhibition in vivo may be a therapeutic target for breast cancer bone metastases. Conflict of interest statement: None declared.
Oncogene, 2007
Tumor cells with stem cell-like properties can be cultured from human glioblastomas by using cond... more Tumor cells with stem cell-like properties can be cultured from human glioblastomas by using conditions that select for the expansion of neural stem cells. We generated cell lines from glioblastoma specimens with the goal to obtain model systems for glioma stem cell biology. Unsupervised analysis of the expression profiles of nine cell lines established under neural stem cell conditions yielded two distinct clusters. Four cell lines were characterized by the expression of neurodevelopmental genes. They showed a multipotent differentiation profile along neuronal, astroglial and oligodendroglial lineages, grew spherically in vitro, expressed CD133 and formed highly invasive tumors in vivo. The other five cell lines shared expression signatures enriched for extracellular matrix-related genes, had a more restricted differentiation capacity, contained no or fewer CD133 þ cells, grew semiadherent or adherent in vitro and displayed reduced tumorigenicity and invasion in vivo. Our findings show that stable, multipotent glioblastoma cell lines with a full stem-like phenotype express neurodevelopmental genes as a distinctive feature, which may offer therapeutic targeting opportunities. The generation of another distinct cluster of cell lines showing similarly homogeneous profiling but restricted stem cell properties suggests that different phenotypes exist, each of which may lead to the typical appearance of glioblastoma.
Modelización …, 2008
Boluda-Botella N., Cases V., Gomis V., León VM, and Soriano R. ... Chemical Engineering Departmen... more Boluda-Botella N., Cases V., Gomis V., León VM, and Soriano R. ... Chemical Engineering Department, University of Alicante. Apdo. 99, E-03080 Alicante (Spain). Tel.+34 965903400, ext.2647. Fax:+34 965903826. ... LAS Standard: 12.1% C LAS, 34.1% C LAS, 30.6% C ...
alliancefordonation.org
... Ashley E. Anker, MA Department of Communication University at Buffalo, The State University o... more ... Ashley E. Anker, MA Department of Communication University at Buffalo, The State University of New York Buffalo, New York, USA ... Tera Kane, BA Department of Communication University at Buffalo, The State University of New York Buffalo, New York, USA ...
Geriatric Nursing, 1994
In a survey of directors of nursing services of 101 nursing homes, it was found that 17 homes sti... more In a survey of directors of nursing services of 101 nursing homes, it was found that 17 homes still used syringes to feed some of their frail residents. Three of these 17 facilities did not have easy access to speech pathologists, and the facility feeding the greatest number of residents by syringe did not use the services of a speech pathologist to assess swallowing. The practice of syringe feeding seems to be going out of favor, but until this practice is no longer used it is hoped that the recommendations in this article will increase the knowledge and awareness of professional nurses, who are often instrumental in coordinating the difficult and complex decision to syringe feed.
Purification of high added value products obtained by fermentation processes is a key research ta... more Purification of high added value products obtained by fermentation processes is a key research task in current biotechnology, especially the ones concerning proteins of very similar molecular structure such as isoenzymes. Purification and separation of biomolecules by commercial ion exchangers is an attractive alternative to affinity chromatography due to its availability and lower cost. For this reason and for its
... Soriano, R., Bautista, LF, Martínez, M. and Aracil, J. (1999), Adsorption isotherms of the As... more ... Soriano, R., Bautista, LF, Martínez, M. and Aracil, J. (1999), Adsorption isotherms of the Aspergillus niger glucoamylases I and II on the ... named glucoamylase I and glucoamylase II) on the resin DEAE–Toyopearl 650 are presented and fitted to the Langmuir model and Henry's ...