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Papers by Alessandra Redolfi

Research paper thumbnail of Transient deficit in acute stroke: a case of musical hallucinations

Neuropsychological trends, Apr 1, 2024

We reported a case of a 62-year-old female patient affected by musical hallucinations (MHs) as a ... more We reported a case of a 62-year-old female patient affected by musical hallucinations (MHs) as a transient symptom after an ischemic stroke in the right middle cerebral artery. CT scan showed widespread cortical and subcortical hypodensity associated with moderate hemorrhage involving the lentiform nucleus, insular cortex, and caudate nucleus. The patient had no history of psychiatric disorders, hearing defects, or epilepsy. MHs appeared one week after the stroke and spontaneously vanished 10 days after their onset. From our perspective, the early activation of MHs after unilateral brain injury, and their timing of resolution, can be explained according to the "interhemispheric imbalance theory". According to this theory, in the minutes or weeks following the onset of a focal cerebrovascular event, a series of changes in global brain connectivity occur leading to a temporary imbalance in interhemispheric excitation.

Research paper thumbnail of Sexuality and Traumatic Brain Injury

Springer eBooks, Dec 31, 2022

Research paper thumbnail of When a parent suffers ABI: Investigation of emotional distress in children

Brain Injury, 2017

Primary objective: To investigate the type of emotional and behavioural impact that having a pare... more Primary objective: To investigate the type of emotional and behavioural impact that having a parent with a severe acquired brain injury (ABI) has on children during the first period of adjustment. Methods and procedure: The study involved 25 couples in which one of the spouses was affected by ABI, and their 35 children (3-14 years). The children attended three sessions with a psychologist aimed at identifying their spontaneous playing and relational behaviour by means of a grid created on the basis of ICD-10 criteria. Both members of each parental couple attended a session with the psychologist, and were administered the Dyadic Adjustment Scale, the 36-item Health Survey and the Caregiver Burden Inventory. Results: 63% of the children showed signs of emotional suffering, the presence of which was underestimated by their parents on the basis of the psychologist's assessments. The variables that correlated most closely with the children's psychological condition were related to the quality of their parents' relationship. Conclusions: Our findings confirm the need for early interventions aimed at both parents and their children in order to investigate the children's emotional-affective situation, and favour an understanding of their discomfort by their parents.

Research paper thumbnail of Clinical replicability of rehabilitation interventions in randomized controlled trials reported in main journals is inadequate

Journal of Clinical Epidemiology, 2019

Objective. To study if Randomized Controlled Trials (RCTs) in rehabilitation (a field where compl... more Objective. To study if Randomized Controlled Trials (RCTs) in rehabilitation (a field where complex interventions prevail) published in main journals include all the details needed to replicate the intervention in clinical practice (clinical replicability). Study Design and Setting. Forty-seven rehabilitation clinicians of 5 professions from 7 teams (Belgium,

Research paper thumbnail of Long-term services for the care and rehabilitation of people with severe acquired brain injury: a multicentre, cross-sectional study of 536 Italian families

Annali dell'Istituto superiore di sanita

People with severe acquired brain injuries (ABIs) require complex, long-term multidisciplinary he... more People with severe acquired brain injuries (ABIs) require complex, long-term multidisciplinary healthcare, and social welfare programmes, and their families experience social and emotional consequences that profoundly condition their quality of life. To investigate whether the possibility of gaining access to local rehabilitation and other services positively influences not only the quality of life of the patients but also the quality of life of their families. The sample consisted of 536 families of patients with severe ABIs. They were administered a specific 50-item questionnaire with a mix of multiple choice answers, dichotomous (yes/no) answers, or answers based on a Likert-type scale. The results suggest that the long-term services provided to patients are substantially satisfactory but the data concerning the patients' social and working reintegration are discomforting. Furthermore, the families experience profound social discomfort related to their economic, emotional and...

Research paper thumbnail of La formazione cognitivo-comportamentale influisce sulla percezione di autoefficacia?

QUADERNI DI PSICOTERAPIA COGNITIVA, 2015

In letteratura e stato studiato il senso di autoefficacia nei terapeuti in formazione ad orientam... more In letteratura e stato studiato il senso di autoefficacia nei terapeuti in formazione ad orientamento cognitivo-comportamentale; alcuni dati mostrano come l’autoefficacia sia incrementata dall’attitudine positiva e dalla capacita di orientamento al problema, mentre diminuisce negli allievi con alti livelli di nevroticismo e che utilizzano strategie di evitamento. Risultati controversi sono stati raccolti in merito all’effetto del numero di drop-out subiti dagli specializzandi, ne vi e accordo nell’affermare che l’autoefficacia si modifichi nel corso del percorso formativo. Nel presente lavoro si intende indagare il senso di autoefficacia negli specializzandi ad orientamento cognitivo-comportamentale, verificando quali variabili possano incidere su di essa in modo significativo; verranno presentati due studi: lo Studio 1 intende verificare l’eventuale relazione tra il numero di pazienti, relativa categoria diagnostica ed autoefficacia. Lo Studio 2 vuole valutare un gruppo di allievi durante il loro percorso formativo al fine di approfondire la relazione tra autoefficacia, coping, personalita, numero e tipologia di pazienti in carico. I risultati dello Studio 1 mostrano come l’autoefficacia sia positivamente associata al numero di pazienti trattati e alla diagnosi di asse I (DSM-IV-TR). Inoltre, i risultati dello Studio 2 su 98 studenti del primo anno di formazione hanno confermato come il senso di autoefficacia sia incrementato dall’attitudine positiva e dall’orientamento al problema, mentre non sia influenzato dal numero di drop-out. Diversamente, il numero e la psicopatologia dei pazienti in carico non risultano essere associati al senso di autoefficacia forse a causa dello scarso numero di pazienti trattati durante il primo anno di formazione.

Research paper thumbnail of Robotic Rehabilitation: An Opportunity to Improve Cognitive Functions in Subjects With Stroke. An Explorative Study

Frontiers in Neurology, 2020

Research paper thumbnail of Can COVID-19 results in cognitive dysfunctions? The need for a multidisciplinary approach in rehabilitation for post-COVID-19 people

European Journal of Physical and Rehabilitation Medicine

Research paper thumbnail of Influence of Cognitive Impairment on the Recovery of Subjects with Subacute Stroke Undergoing Upper Limb Robotic Rehabilitation

Brain Sciences

Cognitive decline is often present in stroke survivors, with a significant impact on motor recove... more Cognitive decline is often present in stroke survivors, with a significant impact on motor recovery. However, how specific cognitive domains could impact motor recovery after robotic rehabilitation in patients with stroke is still not well understood. In this study, we analyzed the relationship between cognitive impairment and the outcome of a robot-mediated upper limb rehabilitation intervention in a sample of 51 subacute stroke patients. Participants were enrolled and treated with a set of robotic and sensor-based devices. Before the intervention, patients underwent a cognitive assessment by means of the Oxford Cognitive Screen. To assess the effect of the 30-session rehabilitation intervention, patients were assessed twice with the following outcome measures: the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), to evaluate motor function; the Upper limb Motricity Index (MI), to evaluate upper limb muscle strength; the Modified Barthel Index (mBI), to evaluate activities of dai...

Research paper thumbnail of Transient deficit in acute stroke: a case of musical hallucinations

Neuropsychological trends, Apr 1, 2024

We reported a case of a 62-year-old female patient affected by musical hallucinations (MHs) as a ... more We reported a case of a 62-year-old female patient affected by musical hallucinations (MHs) as a transient symptom after an ischemic stroke in the right middle cerebral artery. CT scan showed widespread cortical and subcortical hypodensity associated with moderate hemorrhage involving the lentiform nucleus, insular cortex, and caudate nucleus. The patient had no history of psychiatric disorders, hearing defects, or epilepsy. MHs appeared one week after the stroke and spontaneously vanished 10 days after their onset. From our perspective, the early activation of MHs after unilateral brain injury, and their timing of resolution, can be explained according to the "interhemispheric imbalance theory". According to this theory, in the minutes or weeks following the onset of a focal cerebrovascular event, a series of changes in global brain connectivity occur leading to a temporary imbalance in interhemispheric excitation.

Research paper thumbnail of Sexuality and Traumatic Brain Injury

Springer eBooks, Dec 31, 2022

Research paper thumbnail of When a parent suffers ABI: Investigation of emotional distress in children

Brain Injury, 2017

Primary objective: To investigate the type of emotional and behavioural impact that having a pare... more Primary objective: To investigate the type of emotional and behavioural impact that having a parent with a severe acquired brain injury (ABI) has on children during the first period of adjustment. Methods and procedure: The study involved 25 couples in which one of the spouses was affected by ABI, and their 35 children (3-14 years). The children attended three sessions with a psychologist aimed at identifying their spontaneous playing and relational behaviour by means of a grid created on the basis of ICD-10 criteria. Both members of each parental couple attended a session with the psychologist, and were administered the Dyadic Adjustment Scale, the 36-item Health Survey and the Caregiver Burden Inventory. Results: 63% of the children showed signs of emotional suffering, the presence of which was underestimated by their parents on the basis of the psychologist's assessments. The variables that correlated most closely with the children's psychological condition were related to the quality of their parents' relationship. Conclusions: Our findings confirm the need for early interventions aimed at both parents and their children in order to investigate the children's emotional-affective situation, and favour an understanding of their discomfort by their parents.

Research paper thumbnail of Clinical replicability of rehabilitation interventions in randomized controlled trials reported in main journals is inadequate

Journal of Clinical Epidemiology, 2019

Objective. To study if Randomized Controlled Trials (RCTs) in rehabilitation (a field where compl... more Objective. To study if Randomized Controlled Trials (RCTs) in rehabilitation (a field where complex interventions prevail) published in main journals include all the details needed to replicate the intervention in clinical practice (clinical replicability). Study Design and Setting. Forty-seven rehabilitation clinicians of 5 professions from 7 teams (Belgium,

Research paper thumbnail of Long-term services for the care and rehabilitation of people with severe acquired brain injury: a multicentre, cross-sectional study of 536 Italian families

Annali dell'Istituto superiore di sanita

People with severe acquired brain injuries (ABIs) require complex, long-term multidisciplinary he... more People with severe acquired brain injuries (ABIs) require complex, long-term multidisciplinary healthcare, and social welfare programmes, and their families experience social and emotional consequences that profoundly condition their quality of life. To investigate whether the possibility of gaining access to local rehabilitation and other services positively influences not only the quality of life of the patients but also the quality of life of their families. The sample consisted of 536 families of patients with severe ABIs. They were administered a specific 50-item questionnaire with a mix of multiple choice answers, dichotomous (yes/no) answers, or answers based on a Likert-type scale. The results suggest that the long-term services provided to patients are substantially satisfactory but the data concerning the patients' social and working reintegration are discomforting. Furthermore, the families experience profound social discomfort related to their economic, emotional and...

Research paper thumbnail of La formazione cognitivo-comportamentale influisce sulla percezione di autoefficacia?

QUADERNI DI PSICOTERAPIA COGNITIVA, 2015

In letteratura e stato studiato il senso di autoefficacia nei terapeuti in formazione ad orientam... more In letteratura e stato studiato il senso di autoefficacia nei terapeuti in formazione ad orientamento cognitivo-comportamentale; alcuni dati mostrano come l’autoefficacia sia incrementata dall’attitudine positiva e dalla capacita di orientamento al problema, mentre diminuisce negli allievi con alti livelli di nevroticismo e che utilizzano strategie di evitamento. Risultati controversi sono stati raccolti in merito all’effetto del numero di drop-out subiti dagli specializzandi, ne vi e accordo nell’affermare che l’autoefficacia si modifichi nel corso del percorso formativo. Nel presente lavoro si intende indagare il senso di autoefficacia negli specializzandi ad orientamento cognitivo-comportamentale, verificando quali variabili possano incidere su di essa in modo significativo; verranno presentati due studi: lo Studio 1 intende verificare l’eventuale relazione tra il numero di pazienti, relativa categoria diagnostica ed autoefficacia. Lo Studio 2 vuole valutare un gruppo di allievi durante il loro percorso formativo al fine di approfondire la relazione tra autoefficacia, coping, personalita, numero e tipologia di pazienti in carico. I risultati dello Studio 1 mostrano come l’autoefficacia sia positivamente associata al numero di pazienti trattati e alla diagnosi di asse I (DSM-IV-TR). Inoltre, i risultati dello Studio 2 su 98 studenti del primo anno di formazione hanno confermato come il senso di autoefficacia sia incrementato dall’attitudine positiva e dall’orientamento al problema, mentre non sia influenzato dal numero di drop-out. Diversamente, il numero e la psicopatologia dei pazienti in carico non risultano essere associati al senso di autoefficacia forse a causa dello scarso numero di pazienti trattati durante il primo anno di formazione.

Research paper thumbnail of Robotic Rehabilitation: An Opportunity to Improve Cognitive Functions in Subjects With Stroke. An Explorative Study

Frontiers in Neurology, 2020

Research paper thumbnail of Can COVID-19 results in cognitive dysfunctions? The need for a multidisciplinary approach in rehabilitation for post-COVID-19 people

European Journal of Physical and Rehabilitation Medicine

Research paper thumbnail of Influence of Cognitive Impairment on the Recovery of Subjects with Subacute Stroke Undergoing Upper Limb Robotic Rehabilitation

Brain Sciences

Cognitive decline is often present in stroke survivors, with a significant impact on motor recove... more Cognitive decline is often present in stroke survivors, with a significant impact on motor recovery. However, how specific cognitive domains could impact motor recovery after robotic rehabilitation in patients with stroke is still not well understood. In this study, we analyzed the relationship between cognitive impairment and the outcome of a robot-mediated upper limb rehabilitation intervention in a sample of 51 subacute stroke patients. Participants were enrolled and treated with a set of robotic and sensor-based devices. Before the intervention, patients underwent a cognitive assessment by means of the Oxford Cognitive Screen. To assess the effect of the 30-session rehabilitation intervention, patients were assessed twice with the following outcome measures: the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), to evaluate motor function; the Upper limb Motricity Index (MI), to evaluate upper limb muscle strength; the Modified Barthel Index (mBI), to evaluate activities of dai...