Renan Rodrigues - Academia.edu (original) (raw)
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Papers by Renan Rodrigues
Clinical Ophthalmology, 2019
Design: This is a prospective, observational, consecutive nonrandomized cohort. Patients and meth... more Design: This is a prospective, observational, consecutive nonrandomized cohort. Patients and methods: Sixteen patients (18 eyes) had phacoemulsification surgery, nine eyes had manual incisions and nine eyes had femtosecond incisions. All incisions were performed by the same surgeon. All incisions were evaluated at the 1st and 30th postoperative day with anterior segment optical coherence tomography to evaluate anatomical features. Inclusion criterion was presence of low visual acuity due to cataract. Exclusion criteria were other ocular pathologies, previous trauma, or corneal wound healing disease, as any intra or postoperative complication. Three different corneal specialists analyzed wound architecture features (epithelial or endothelial gap, incision edema, number of planes, Descemet's detachment, and loss of wound sealing) at both visits. ImageJ (National Institutes of Health) software was also used to analyze anatomical features of incisions. Results: Almost all incisions had edema at the first postoperative day. All femto incisions were triplanar, as intended, unlike manual incisions, which showed two uniplanar incisions (P=0.009). All laser incisions presented partial loss of wound sealing, while five keratome incisions had no loss of wound sealing at the first postoperative day (P=0.03). Conclusion: These findings support the hypothesis that laser constructed incisions are more precisely constructed than manual, although corneal wound healing was similar between the two groups at the 30th postoperative day, with a tendency to a faster anatomical improvement in the keratome group.
Arquivos Brasileiros de Oftalmologia, 2014
Current telemedicine systems have addressed these issues by pro viding global integration and by ... more Current telemedicine systems have addressed these issues by pro viding global integration and by enabling the sharing of data, images, and voices from different sources and applications (2,3). Telemedicine is also a powerful tool for alleviating the lack of doctors in resource-poor areas. Furthermore, it is a viable option for almost all medical specialties, particularly those for which images comprise the main diagnostic tool (4-7). Thus, the fields of radiology, dermatology, pathology, ultrasound, and ophthalmology, among others (8-12) , are especially favorable for the establishment of data transmission protocols with diagnostic purposes (13,14). Ophthalmology, for example, can greatly benefit from telemedicine (15,16) , as it is crucial to identify patients that present urgent cases in order to avoid morbidity and permanent disorders (17). Situations such as ocular trauma, chemical burns, corneal ulcers, orbit cellulites, retinal A teleophthalmology system for the diagnosis of ocular urgency in remote areas of Brazil Um sistema de teleoftalmologia para triagem de urgências em áreas remotas do Brasil
Arquivos Brasileiros de Oftalmologia, 2014
(UNIFESP) on 12 patients who presented with pale yellowish preretinal dots. Confirmation of ocula... more (UNIFESP) on 12 patients who presented with pale yellowish preretinal dots. Confirmation of ocular syphilis was based on clinical manifestations, and all patients were submitted to both Venereal Disease Research Laboratory (VDRL) and FTA-Abs for syphilis. In addition, lum bar puncture was performed. After diagnostic confirmation of syphilis, fundus photographs and optical coherence of tomography (OCT) (Figure 3) were performed to identify the localization of dots.
Arquivos Brasileiros de Oftalmologia
To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (36... more To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (365 nm) submitted for crosslinking. Methods: This in vitro, benchtop experiment using cadaver tissue study analyzed 12 porcine corneal lamellas, which were obtained using a microkeratome after mechanical de-epithelization and separated into three thickness groups: 180, 300, and 360 µm. The corneal thickness values were measured by anterior-segment optical coherence tomography. All lamellas had ultraviolet-A (365 nm) absorbance measured with a 96-well plate spectrophotometer using an ultraviolet transparent microplate before riboflavin instillation and pre-and post-crosslinking according to the Dresden protocol. Results: The ultraviolet absorbance profiles of the 180, 300, and 360 µm groups were obtained as a-coefficients of 12.85, 76.55, and 120.27, respectively. A theoretical formula was calculated though a statistical analysis that demonstrated the correlation between stromal lamellar thickness and ultraviolet absorbance. Conclusions: Corneal thickness and ultraviolet-A spectral absorbance of corneal lamellas showed linear correlation. These findings can potentially contribute to the optimization of ultraviolet-A application during crosslinking, making the treatment of corneas with thickness <400 µm safe and personalized energy delivery for each corneal thickness.
Arquivos Brasileiros de Oftalmologia, 2024
To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (36... more To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (365 nm) submitted for crosslinking. Methods: This in vitro, benchtop experiment using cadaver tissue study analyzed 12 porcine corneal lamellas, which were obtained using a microkeratome after mechanical de-epithelization and separated into three thickness groups: 180, 300, and 360 µm. The corneal thickness values were measured by anterior-segment optical coherence tomography. All lamellas had ultraviolet-A (365 nm) absorbance measured with a 96-well plate spectrophotometer using an ultraviolet transparent microplate before riboflavin instillation and pre-and post-crosslinking according to the Dresden protocol. Results: The ultraviolet absorbance profiles of the 180, 300, and 360 µm groups were obtained as a-coefficients of 12.85, 76.55, and 120.27, respectively. A theoretical formula was calculated though a statistical analysis that demonstrated the correlation between stromal lamellar thickness and ultraviolet absorbance. Conclusions: Corneal thickness and ultraviolet-A spectral absorbance of corneal lamellas showed linear correlation. These findings can potentially contribute to the optimization of ultraviolet-A application during crosslinking, making the treatment of corneas with thickness <400 µm safe and personalized energy delivery for each corneal thickness.
Clinical Ophthalmology, 2019
Design: This is a prospective, observational, consecutive nonrandomized cohort. Patients and meth... more Design: This is a prospective, observational, consecutive nonrandomized cohort. Patients and methods: Sixteen patients (18 eyes) had phacoemulsification surgery, nine eyes had manual incisions and nine eyes had femtosecond incisions. All incisions were performed by the same surgeon. All incisions were evaluated at the 1st and 30th postoperative day with anterior segment optical coherence tomography to evaluate anatomical features. Inclusion criterion was presence of low visual acuity due to cataract. Exclusion criteria were other ocular pathologies, previous trauma, or corneal wound healing disease, as any intra or postoperative complication. Three different corneal specialists analyzed wound architecture features (epithelial or endothelial gap, incision edema, number of planes, Descemet's detachment, and loss of wound sealing) at both visits. ImageJ (National Institutes of Health) software was also used to analyze anatomical features of incisions. Results: Almost all incisions had edema at the first postoperative day. All femto incisions were triplanar, as intended, unlike manual incisions, which showed two uniplanar incisions (P=0.009). All laser incisions presented partial loss of wound sealing, while five keratome incisions had no loss of wound sealing at the first postoperative day (P=0.03). Conclusion: These findings support the hypothesis that laser constructed incisions are more precisely constructed than manual, although corneal wound healing was similar between the two groups at the 30th postoperative day, with a tendency to a faster anatomical improvement in the keratome group.
Arquivos Brasileiros de Oftalmologia, 2014
Current telemedicine systems have addressed these issues by pro viding global integration and by ... more Current telemedicine systems have addressed these issues by pro viding global integration and by enabling the sharing of data, images, and voices from different sources and applications (2,3). Telemedicine is also a powerful tool for alleviating the lack of doctors in resource-poor areas. Furthermore, it is a viable option for almost all medical specialties, particularly those for which images comprise the main diagnostic tool (4-7). Thus, the fields of radiology, dermatology, pathology, ultrasound, and ophthalmology, among others (8-12) , are especially favorable for the establishment of data transmission protocols with diagnostic purposes (13,14). Ophthalmology, for example, can greatly benefit from telemedicine (15,16) , as it is crucial to identify patients that present urgent cases in order to avoid morbidity and permanent disorders (17). Situations such as ocular trauma, chemical burns, corneal ulcers, orbit cellulites, retinal A teleophthalmology system for the diagnosis of ocular urgency in remote areas of Brazil Um sistema de teleoftalmologia para triagem de urgências em áreas remotas do Brasil
Arquivos Brasileiros de Oftalmologia, 2014
(UNIFESP) on 12 patients who presented with pale yellowish preretinal dots. Confirmation of ocula... more (UNIFESP) on 12 patients who presented with pale yellowish preretinal dots. Confirmation of ocular syphilis was based on clinical manifestations, and all patients were submitted to both Venereal Disease Research Laboratory (VDRL) and FTA-Abs for syphilis. In addition, lum bar puncture was performed. After diagnostic confirmation of syphilis, fundus photographs and optical coherence of tomography (OCT) (Figure 3) were performed to identify the localization of dots.
Arquivos Brasileiros de Oftalmologia
To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (36... more To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (365 nm) submitted for crosslinking. Methods: This in vitro, benchtop experiment using cadaver tissue study analyzed 12 porcine corneal lamellas, which were obtained using a microkeratome after mechanical de-epithelization and separated into three thickness groups: 180, 300, and 360 µm. The corneal thickness values were measured by anterior-segment optical coherence tomography. All lamellas had ultraviolet-A (365 nm) absorbance measured with a 96-well plate spectrophotometer using an ultraviolet transparent microplate before riboflavin instillation and pre-and post-crosslinking according to the Dresden protocol. Results: The ultraviolet absorbance profiles of the 180, 300, and 360 µm groups were obtained as a-coefficients of 12.85, 76.55, and 120.27, respectively. A theoretical formula was calculated though a statistical analysis that demonstrated the correlation between stromal lamellar thickness and ultraviolet absorbance. Conclusions: Corneal thickness and ultraviolet-A spectral absorbance of corneal lamellas showed linear correlation. These findings can potentially contribute to the optimization of ultraviolet-A application during crosslinking, making the treatment of corneas with thickness <400 µm safe and personalized energy delivery for each corneal thickness.
Arquivos Brasileiros de Oftalmologia, 2024
To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (36... more To determine the absorbance coefficient of the thin porcine cornea to ultraviolet-A radiation (365 nm) submitted for crosslinking. Methods: This in vitro, benchtop experiment using cadaver tissue study analyzed 12 porcine corneal lamellas, which were obtained using a microkeratome after mechanical de-epithelization and separated into three thickness groups: 180, 300, and 360 µm. The corneal thickness values were measured by anterior-segment optical coherence tomography. All lamellas had ultraviolet-A (365 nm) absorbance measured with a 96-well plate spectrophotometer using an ultraviolet transparent microplate before riboflavin instillation and pre-and post-crosslinking according to the Dresden protocol. Results: The ultraviolet absorbance profiles of the 180, 300, and 360 µm groups were obtained as a-coefficients of 12.85, 76.55, and 120.27, respectively. A theoretical formula was calculated though a statistical analysis that demonstrated the correlation between stromal lamellar thickness and ultraviolet absorbance. Conclusions: Corneal thickness and ultraviolet-A spectral absorbance of corneal lamellas showed linear correlation. These findings can potentially contribute to the optimization of ultraviolet-A application during crosslinking, making the treatment of corneas with thickness <400 µm safe and personalized energy delivery for each corneal thickness.