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Renee Behrens

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Papers by Renee Behrens

Research paper thumbnail of Changes in endometrial gene expression associated with Infertility

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Research paper thumbnail of Optimising the diagnosis of ectopic pregnancy

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016

This retrospective cohort study reviewed the diagnosis of all ectopic pregnancies within a distri... more This retrospective cohort study reviewed the diagnosis of all ectopic pregnancies within a district general hospital over a 5-year period after the establishment of a dedicated Early Pregnancy Assessment Unit (EPAU). Of 215 ectopic pregnancies identified, notes were available for 208 (97%). Two-hundred and two cases were determined to have been diagnosed and managed as ectopic pregnancies. Six cases were excluded as they were pregnancies of unknown location managed as such. Overall, 91% were diagnosed by ultrasound scan, 5% were diagnosed clinically and 3% were diagnosed on serial human chorionic gonadotrophin (hCG) levels. This study found that the introduction of a dedicated, multi-professional, EPAU with a stable workforce improved ultrasound visualisation of ectopic pregnancies at first ultrasound scan from 22% prior to its commencement, to 61% over this period. The improvement in positive scan diagnosis of ectopic pregnancy was associated with a reduction in negative laparoscop...

Research paper thumbnail of A 5-year experience of the changing management of ectopic pregnancy

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016

This retrospective audit reviewed all ectopic pregnancies over a 5-year period in a district gene... more This retrospective audit reviewed all ectopic pregnancies over a 5-year period in a district general hospital setting. Of 215 ectopic pregnancies identified, notes were available for 208 (97%). 202 cases were determined to have been diagnosed and managed as ectopic pregnancies. Six cases were excluded as they were pregnancies of unknown location managed as such. The proportion of patients managed non-surgically has increased following the introduction of our consultant-led early pregnancy assessment unit from 25% prior to 31% currently. The success rates have improved in both those managed expectantly (50%-73%) and those with methotrexate (75%-90%). There has been a corresponding drop in those managed surgically from 75% to 69%, and a reduction in negative laparoscopies from 13% to 6%. Provided recommended criteria and follow-up are adhered to, non-surgical management has been shown to have comparative safety to traditional surgical management with acceptable efficacy and patient ac...

Research paper thumbnail of Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility

Cochrane Database of Systematic Reviews, 2010

Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility.

Research paper thumbnail of Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial

Research paper thumbnail of Changes in endometrial gene expression associated with Infertility

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Research paper thumbnail of Optimising the diagnosis of ectopic pregnancy

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016

This retrospective cohort study reviewed the diagnosis of all ectopic pregnancies within a distri... more This retrospective cohort study reviewed the diagnosis of all ectopic pregnancies within a district general hospital over a 5-year period after the establishment of a dedicated Early Pregnancy Assessment Unit (EPAU). Of 215 ectopic pregnancies identified, notes were available for 208 (97%). Two-hundred and two cases were determined to have been diagnosed and managed as ectopic pregnancies. Six cases were excluded as they were pregnancies of unknown location managed as such. Overall, 91% were diagnosed by ultrasound scan, 5% were diagnosed clinically and 3% were diagnosed on serial human chorionic gonadotrophin (hCG) levels. This study found that the introduction of a dedicated, multi-professional, EPAU with a stable workforce improved ultrasound visualisation of ectopic pregnancies at first ultrasound scan from 22% prior to its commencement, to 61% over this period. The improvement in positive scan diagnosis of ectopic pregnancy was associated with a reduction in negative laparoscop...

Research paper thumbnail of A 5-year experience of the changing management of ectopic pregnancy

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2016

This retrospective audit reviewed all ectopic pregnancies over a 5-year period in a district gene... more This retrospective audit reviewed all ectopic pregnancies over a 5-year period in a district general hospital setting. Of 215 ectopic pregnancies identified, notes were available for 208 (97%). 202 cases were determined to have been diagnosed and managed as ectopic pregnancies. Six cases were excluded as they were pregnancies of unknown location managed as such. The proportion of patients managed non-surgically has increased following the introduction of our consultant-led early pregnancy assessment unit from 25% prior to 31% currently. The success rates have improved in both those managed expectantly (50%-73%) and those with methotrexate (75%-90%). There has been a corresponding drop in those managed surgically from 75% to 69%, and a reduction in negative laparoscopies from 13% to 6%. Provided recommended criteria and follow-up are adhered to, non-surgical management has been shown to have comparative safety to traditional surgical management with acceptable efficacy and patient ac...

Research paper thumbnail of Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility

Cochrane Database of Systematic Reviews, 2010

Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility.

Research paper thumbnail of Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial

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