Reuben Kaufman - Academia.edu (original) (raw)
Papers by Reuben Kaufman
Ticks and Tick-borne Diseases, Oct 1, 2014
The Journal of Experimental Biology, Aug 1, 1981
Experimental and Applied Acarology, Nov 18, 2020
Canadian Entomologist, Apr 1, 1971
The pulsatile organ, or "accessory heart," in the tibia of Triatoma consists of a membr... more The pulsatile organ, or "accessory heart," in the tibia of Triatoma consists of a membrane which divides the femur and tibia into a series of sinuses, a pulsatile muscle which propels the haemolymph through the sinuses, and a valvular membrane, which imposes unidirectional flow on the system. A possible innervation of the muscle is described, and simple experiments involving nerve stimulation demonstrate that the pulsatile muscle is under nervous control. Using partially isolated preparations of the pulsatile organ, it has been shown that the organ responds to dopamine and serotonin, but fails to respond to acetylcholine. The pulsatile muscle therefore resembles visceral muscle rather than skeletal muscle.
Journal of Insect Physiology, May 1, 2016
Elsevier eBooks, 1982
Publisher Summary This chapter discusses the mechanisms of tick excretion. It also discusses the ... more Publisher Summary This chapter discusses the mechanisms of tick excretion. It also discusses the physiological aspects of salivation in ticks. The existence of a pore on the first coxal joint in argasid ticks from which a fluid is excreted during feeding or as a result of mild trauma, has been recognized at least since the turn of the century. For much of that time, the functional significance of the coxal organ associated with that pore was a matter of speculation. The coxal tubule is composed of two distinct cell types—a cuboidal to somewhat flattened cell with relatively long microvilli and a large nucleus and a more columnar cell with a small nucleus and short microvilli. The cuboidal cells are found in the proximal segment of the coxal tubule, relative to its junction with the filtration membrane, and the columnar cells form the distal segment. The coxal fluid of several argasid ticks is less concentrated than the hemolymph, at least with regard to chloride. As ultrafiltration is non-selective with regard to small molecules, it is likely that the tubular portion of the organ is concerned with the recapture of metabolically useful substances, including some ions.
The Journal of Experimental Biology, Apr 1, 1973
The Journal of Experimental Biology, Jun 1, 1976
Experimental and Applied Acarology, Dec 9, 2020
... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer ... more ... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer (USA) Dr. Michael Samish (Israel) Prof. Sarah Randolph (UK) Prof. Daniel Sonenshine (USA) Dr. DeMar Taylor (Japan) Local Organizing Committee Prof. W. Reuben Kaufman (Chair, U ...
Insect Biochemistry and Molecular Biology, Jul 1, 2002
Most ixodid ticks must feed for at least a few days to complete gonad maturation. Substances prod... more Most ixodid ticks must feed for at least a few days to complete gonad maturation. Substances produced by the mature male gonad, and carried in the spermatophore, induce physiological changes in the female that lead to engorgement and oviposition. To begin defining the molecular phenotype at this stage of male development, we differentially cross-screened a cDNA library made from the
The Journal of Parasitology, 1978
Development of the protozoan parasite Nuttallia danii was observed in salivary glands which were ... more Development of the protozoan parasite Nuttallia danii was observed in salivary glands which were extirpated from Hyalomma anatolicum excavatum nymphs, fed as larvae on infected gerbils and held in organ culture. At 34 C the parasite continued developing in the cultured glands at a rate similar to that observed under normal conditions. Development also occurred in culture at 25 degrees C, but at a somewhat slower rate.
Canadian Journal of Zoology, 1980
Tick (Amblyomma hebraeum) salivary glands are a rich source of Na,K-ATPase (EC 3.6.1.3), the fund... more Tick (Amblyomma hebraeum) salivary glands are a rich source of Na,K-ATPase (EC 3.6.1.3), the fundamental properties of which are similar to those of Na,K-ATPases from other sources. Inhibition of the enzyme by ouabain is quantitatively similar to the inhibition of fluid secretion by this drug. Harmaline at high concentrations also inhibited the Na,K-ATPase. The nucleotides GTP, ITP, and UTP were utilized as substrates, but all were less effective than ATP. Noradrenaline, dopamine, and phenoxybenzamine, all at concentrations known to influence fluid secretion in vitro, had no effect on enzyme activity.
... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer ... more ... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer (USA) Dr. Michael Samish (Israel) Prof. Sarah Randolph (UK) Prof. Daniel Sonenshine (USA) Dr. DeMar Taylor (Japan) Local Organizing Committee Prof. W. Reuben Kaufman (Chair, U ...
Recent Advances in Acarology, 1979
Journal of Medical Entomology, 1994
Ticks and Tick-borne Diseases, Oct 1, 2014
The Journal of Experimental Biology, Aug 1, 1981
Experimental and Applied Acarology, Nov 18, 2020
Canadian Entomologist, Apr 1, 1971
The pulsatile organ, or "accessory heart," in the tibia of Triatoma consists of a membr... more The pulsatile organ, or "accessory heart," in the tibia of Triatoma consists of a membrane which divides the femur and tibia into a series of sinuses, a pulsatile muscle which propels the haemolymph through the sinuses, and a valvular membrane, which imposes unidirectional flow on the system. A possible innervation of the muscle is described, and simple experiments involving nerve stimulation demonstrate that the pulsatile muscle is under nervous control. Using partially isolated preparations of the pulsatile organ, it has been shown that the organ responds to dopamine and serotonin, but fails to respond to acetylcholine. The pulsatile muscle therefore resembles visceral muscle rather than skeletal muscle.
Journal of Insect Physiology, May 1, 2016
Elsevier eBooks, 1982
Publisher Summary This chapter discusses the mechanisms of tick excretion. It also discusses the ... more Publisher Summary This chapter discusses the mechanisms of tick excretion. It also discusses the physiological aspects of salivation in ticks. The existence of a pore on the first coxal joint in argasid ticks from which a fluid is excreted during feeding or as a result of mild trauma, has been recognized at least since the turn of the century. For much of that time, the functional significance of the coxal organ associated with that pore was a matter of speculation. The coxal tubule is composed of two distinct cell types—a cuboidal to somewhat flattened cell with relatively long microvilli and a large nucleus and a more columnar cell with a small nucleus and short microvilli. The cuboidal cells are found in the proximal segment of the coxal tubule, relative to its junction with the filtration membrane, and the columnar cells form the distal segment. The coxal fluid of several argasid ticks is less concentrated than the hemolymph, at least with regard to chloride. As ultrafiltration is non-selective with regard to small molecules, it is likely that the tubular portion of the organ is concerned with the recapture of metabolically useful substances, including some ions.
The Journal of Experimental Biology, Apr 1, 1973
The Journal of Experimental Biology, Jun 1, 1976
Experimental and Applied Acarology, Dec 9, 2020
... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer ... more ... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer (USA) Dr. Michael Samish (Israel) Prof. Sarah Randolph (UK) Prof. Daniel Sonenshine (USA) Dr. DeMar Taylor (Japan) Local Organizing Committee Prof. W. Reuben Kaufman (Chair, U ...
Insect Biochemistry and Molecular Biology, Jul 1, 2002
Most ixodid ticks must feed for at least a few days to complete gonad maturation. Substances prod... more Most ixodid ticks must feed for at least a few days to complete gonad maturation. Substances produced by the mature male gonad, and carried in the spermatophore, induce physiological changes in the female that lead to engorgement and oviposition. To begin defining the molecular phenotype at this stage of male development, we differentially cross-screened a cDNA library made from the
The Journal of Parasitology, 1978
Development of the protozoan parasite Nuttallia danii was observed in salivary glands which were ... more Development of the protozoan parasite Nuttallia danii was observed in salivary glands which were extirpated from Hyalomma anatolicum excavatum nymphs, fed as larvae on infected gerbils and held in organ culture. At 34 C the parasite continued developing in the cultured glands at a rate similar to that observed under normal conditions. Development also occurred in culture at 25 degrees C, but at a somewhat slower rate.
Canadian Journal of Zoology, 1980
Tick (Amblyomma hebraeum) salivary glands are a rich source of Na,K-ATPase (EC 3.6.1.3), the fund... more Tick (Amblyomma hebraeum) salivary glands are a rich source of Na,K-ATPase (EC 3.6.1.3), the fundamental properties of which are similar to those of Na,K-ATPases from other sources. Inhibition of the enzyme by ouabain is quantitatively similar to the inhibition of fluid secretion by this drug. Harmaline at high concentrations also inhibited the Na,K-ATPase. The nucleotides GTP, ITP, and UTP were utilized as substrates, but all were less effective than ATP. Noradrenaline, dopamine, and phenoxybenzamine, all at concentrations known to influence fluid secretion in vitro, had no effect on enzyme activity.
... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer ... more ... IV (USA) Dr. Agustin Estrada-Pena (Spain) Prof. Albert Neitz (South Africa) Prof. Guy Palmer (USA) Dr. Michael Samish (Israel) Prof. Sarah Randolph (UK) Prof. Daniel Sonenshine (USA) Dr. DeMar Taylor (Japan) Local Organizing Committee Prof. W. Reuben Kaufman (Chair, U ...
Recent Advances in Acarology, 1979
Journal of Medical Entomology, 1994