Reza Hamidian - Academia.edu (original) (raw)

Papers by Reza Hamidian

Research paper thumbnail of DOES MAGNESIUM AFFECT THE RISK OF ATRIAL FIBRILLATION? AN APPROACH USING GENERALIZED ADDITIVE LOGISTIC REGRESSION

Advances and Applications in Statistics, Jun 1, 2009

The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is co... more The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is controversial and there are antonym results in the literature. We studied the relationship between prophylactic magnesium and cardiac arrhythmic using two different statistical approaches. These two approaches are the ordinary logistic regression and generalized additive logistic regression. The ordinary logistic regression was unable to show any significant relation between magnesium level and post coronary artery bypass ...

Research paper thumbnail of Magnesium infusion and postoperative atrial fibrillation: a randomized clinical trial

Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2007

Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum... more Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum magnesium concentration will change after coronary bypass surgery but compensatory prophylactic administration of magnesium has remained a controversial issue. We studied whether prophylactic administration of magnesium could prevent post-coronary artery bypass grafting (CABG) arrhythmias and evaluated the effects of diabetes mellitus on prophylactic magnesium administration. In a clinical trial, 345 consecutive CABG candidates were randomly assigned to study (n = 166, 48.1%) and control groups. Patients in study group received supplemental magnesium infusion as following: 2 g [corrected] after induction of anesthesia until cardio-pulmonary bypass and then 8 g upon arrival in Intensive Care Unit (ICU) until 24 hr. Total serum magnesium concentration was measured at four designated time points: onset of induction, and 0, 24 and 48 hr after ICU admission. Cardiac arrhythmias were sought w...

Research paper thumbnail of Magnesium infusion and postoperative atrial fibrillation: a randomized clinical trial

Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum... more Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum magnesium concentration will change after coronary bypass surgery but compensatory prophylactic administration of magnesium has remained a controversial issue. We studied whether prophylactic administration of magnesium could prevent post-coronary artery bypass grafting (CABG) arrhythmias and evaluated the effects of diabetes mellitus on prophylactic magnesium administration. In a clinical trial, 345 consecutive CABG candidates were randomly assigned to study (n = 166, 48.1%) and control groups. Patients in study group received supplemental magnesium infusion as following: 2 g [corrected] after induction of anesthesia until cardio-pulmonary bypass and then 8 g upon arrival in Intensive Care Unit (ICU) until 24 hr. Total serum magnesium concentration was measured at four designated time points: onset of induction, and 0, 24 and 48 hr after ICU admission. Cardiac arrhythmias were sought with a 12-lead electrocardiogram (ECG) from the end of surgery up till discharge. Atrial Fibrillation (Af) occurred in 34 patients (9.9%). Total serum magnesium concentration was significantly higher in patients who received supplemental magnesium (P < 0.001) and significantly lower in Af patients (P= 0.02). Among non-diabetics, Af incidence was significantly lower in study group compared with control group. The occurrence of atrial fibrillation correlates with serum magnesium level. Diabetes mellitus probably hampers prophylactic effect of supplemental magnesium in preventing the occurrence of Af.

Research paper thumbnail of Correlation between lipoprotein(a) serum concentration and severity of coronary artery stenosis in an Iranian population according to Gensini score

Clinical Biochemistry, 2008

Objectives: To investigate the correlation between serum lipoprotein(a) concentration and existen... more Objectives: To investigate the correlation between serum lipoprotein(a) concentration and existence as well as severity of coronary atherosclerosis. Design and methods: A cross-sectional study was conducted on 826 patients who underwent angiography through measuring blood sugar, serum lipids, lipoprotein(a) and evaluation of coronary stenosis by Gensini score.

Research paper thumbnail of DOES MAGNESIUM AFFECT THE RISK OF ATRIAL FIBRILLATION? AN APPROACH USING GENERALIZED ADDITIVE LOGISTIC REGRESSION

Abstract The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythm... more Abstract The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is controversial and there are antonym results in the literature. We studied the relationship between prophylactic magnesium and cardiac arrhythmic using two different statistical approaches. These two approaches are the ordinary logistic regression and generalized additive logistic regression. The ordinary logistic regression was unable to show any significant relation between magnesium level and post coronary artery bypass ...

Research paper thumbnail of The Association of Air Pollution and Emergency Medical Service Seeking

There are some reports on the association between air pollution and myocardial infarction, arrhyt... more There are some reports on the association between air pollution and myocardial infarction, arrhythmia, and mortality due to cardiac problems in susceptible individuals. We aimed to evaluate the association of air pollution and the emergency visits due to cardiovascular diseases, in a specialized heart hospital in Tehran.

Research paper thumbnail of Air Pollution and In-Hospital Mortality of Ischemic Heart Disease Patients

Journal of Biological Sciences, 2010

Research paper thumbnail of Efficacy of Double and Triple Phototherapy in Term Newborns With Hyperbilirubinemia: The First Clinical Trial

Pediatrics and Neonatology, 2009

Background: Icterus is the most common medical problem in neonates and phototherapy is the standa... more Background: Icterus is the most common medical problem in neonates and phototherapy is the standard treatment for neonatal hyperbilirubinemia. This study aimed to compare the efficacy and length of hospital stay of double and triple phototherapy in newborns with indirect hyperbilirubinemia. Methods: In a clinical trial, 40 healthy term newborns (gestational age > 37 weeks) with bilirubin ≥ 12 and ≥ 15 mg/dL in the second and third day, respectively, were randomly assigned to triple (n = 20) or double phototherapy (n = 20) groups. Total and direct serum bilirubin were measured at admission, 8, 16, and 24 hours after beginning of phototherapy, and every 12 hours thereafter until discharge (when bilirubin levels reached ≤ 10 mg/dL). Results: There were 21 male (52%) and 19 female (48%) term neonates, with significant difference between patients' age, weight, and age of icterus. There was no significant difference in the rate of bilirubin decline between the two groups within the first 8, 16 and 24 hours. There was no significant difference in mean length of hospital stay between the two groups. Analysis of complications showed no difference between triple and double groups. Conclusion: Triple phototherapy failed to reduce total serum bilirubin and shorten length of hospitalization more rapidly than double phototherapy.

Research paper thumbnail of ERYTHROCYTIC GLUCOSE6PHOSPHATE DEHYDROGENASE ACTIVITY IN DIABETIC PATIENTS

Background and objectives: Diabetes mellitus is a common and complicated disease. Studies imply b... more Background and objectives: Diabetes mellitus is a common and complicated disease. Studies imply blood glucose and its oxidant derivatives have a key role in pathogenesis of diabetes mellitus. Activity of enzyme "glucose-6-phosphate dehydrogenase" (G6PD), an anti-oxidant system, is important in preventing its complications. Unsuitable control of blood glucose decreases G6PD activity and increases diabetes mellitus complications. This study evaluated the difference of G6PD activity among diabetic and non diabetic patients, and the impact of hyperglycemia on the G6PD activity. Methodology: One hundred diabetic and one hundred non diabetic subjects were selected from patients 30 to 60 years old. Demographic data including gender, age, height, weight, duration of diabetes mellitus, type and duration of treatment, medical history (especially favism) were recorded. Blood pressure and body mass index were also measured. One blood sample was taken from each subject and 5 elements including G6PD presence and activity, fasting plasma glucose, plasma triglyceride and plasma high density lipoprotein were measured. Results: G6PD activity was significantly higher in non diabetic subjects (P<0.01). Within diabetics, G6PD mean activity was significantly higher in non dyslipidemic group (P<0.05) and in subjects with BMI < 25 (P<0.05). G6PD mean activity was significantly higher in non diabetics than dyslipidemic (P<0.01) and non dyslipidemic diabetics (P<0.05). Conclusion: Diabetic hyperglycemia may lead to serious complications and decrease G6PD activity. This issue itself aggravates diabetic injury due to inappropriate antioxidation process. Simultaneous dyslipidemia and obesity may intensify the effect of hyperglycemia and oxidative stress.

Research paper thumbnail of Prevalence of Cardiac Manifestations in HIV-Infected Patients in Iran

Jaids-journal of Acquired Immune Deficiency Syndromes, 2010

... Azar Hadadi, MD*. Sina Moradband Badie, MD†. Maryam Rohamm, MD‡. Mehrnaz Rasoolinejad, MD§. N... more ... Azar Hadadi, MD*. Sina Moradband Badie, MD†. Maryam Rohamm, MD‡. Mehrnaz Rasoolinejad, MD§. Nahid Mirzaee, MD‡. Reza Hamidian, MD*. *Sina Hospital. †Amir Alam Hospital. ‡Imam Khomeini Hospital. Tehran University of Medical Sciences, Tehran, Iran. ...

Research paper thumbnail of Family history of cardiovascular disease as a risk factor for coronary artery disease in adult offspring

Monaldi Arch Chest …, 2008

Background and aims: There is controversy about the role of positive family history as an indepen... more Background and aims: There is controversy about the role of positive family history as an independent risk factor for coronary artery disease. The aim of this work was to investigate the influence of family history on presentation of coronary artery disease in adult offspring, and on its severity.

Research paper thumbnail of DOES MAGNESIUM AFFECT THE RISK OF ATRIAL FIBRILLATION? AN APPROACH USING GENERALIZED ADDITIVE LOGISTIC REGRESSION

Advances and Applications in Statistics, Jun 1, 2009

The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is co... more The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is controversial and there are antonym results in the literature. We studied the relationship between prophylactic magnesium and cardiac arrhythmic using two different statistical approaches. These two approaches are the ordinary logistic regression and generalized additive logistic regression. The ordinary logistic regression was unable to show any significant relation between magnesium level and post coronary artery bypass ...

Research paper thumbnail of Magnesium infusion and postoperative atrial fibrillation: a randomized clinical trial

Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2007

Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum... more Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum magnesium concentration will change after coronary bypass surgery but compensatory prophylactic administration of magnesium has remained a controversial issue. We studied whether prophylactic administration of magnesium could prevent post-coronary artery bypass grafting (CABG) arrhythmias and evaluated the effects of diabetes mellitus on prophylactic magnesium administration. In a clinical trial, 345 consecutive CABG candidates were randomly assigned to study (n = 166, 48.1%) and control groups. Patients in study group received supplemental magnesium infusion as following: 2 g [corrected] after induction of anesthesia until cardio-pulmonary bypass and then 8 g upon arrival in Intensive Care Unit (ICU) until 24 hr. Total serum magnesium concentration was measured at four designated time points: onset of induction, and 0, 24 and 48 hr after ICU admission. Cardiac arrhythmias were sought w...

Research paper thumbnail of Magnesium infusion and postoperative atrial fibrillation: a randomized clinical trial

Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum... more Postoperative arrhythmias are among the most common complications of cardiac surgery. Total serum magnesium concentration will change after coronary bypass surgery but compensatory prophylactic administration of magnesium has remained a controversial issue. We studied whether prophylactic administration of magnesium could prevent post-coronary artery bypass grafting (CABG) arrhythmias and evaluated the effects of diabetes mellitus on prophylactic magnesium administration. In a clinical trial, 345 consecutive CABG candidates were randomly assigned to study (n = 166, 48.1%) and control groups. Patients in study group received supplemental magnesium infusion as following: 2 g [corrected] after induction of anesthesia until cardio-pulmonary bypass and then 8 g upon arrival in Intensive Care Unit (ICU) until 24 hr. Total serum magnesium concentration was measured at four designated time points: onset of induction, and 0, 24 and 48 hr after ICU admission. Cardiac arrhythmias were sought with a 12-lead electrocardiogram (ECG) from the end of surgery up till discharge. Atrial Fibrillation (Af) occurred in 34 patients (9.9%). Total serum magnesium concentration was significantly higher in patients who received supplemental magnesium (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001) and significantly lower in Af patients (P= 0.02). Among non-diabetics, Af incidence was significantly lower in study group compared with control group. The occurrence of atrial fibrillation correlates with serum magnesium level. Diabetes mellitus probably hampers prophylactic effect of supplemental magnesium in preventing the occurrence of Af.

Research paper thumbnail of Correlation between lipoprotein(a) serum concentration and severity of coronary artery stenosis in an Iranian population according to Gensini score

Clinical Biochemistry, 2008

Objectives: To investigate the correlation between serum lipoprotein(a) concentration and existen... more Objectives: To investigate the correlation between serum lipoprotein(a) concentration and existence as well as severity of coronary atherosclerosis. Design and methods: A cross-sectional study was conducted on 826 patients who underwent angiography through measuring blood sugar, serum lipids, lipoprotein(a) and evaluation of coronary stenosis by Gensini score.

Research paper thumbnail of DOES MAGNESIUM AFFECT THE RISK OF ATRIAL FIBRILLATION? AN APPROACH USING GENERALIZED ADDITIVE LOGISTIC REGRESSION

Abstract The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythm... more Abstract The effect of prophylactic administrative of magnesium on postoperative cardiac arrhythmias is controversial and there are antonym results in the literature. We studied the relationship between prophylactic magnesium and cardiac arrhythmic using two different statistical approaches. These two approaches are the ordinary logistic regression and generalized additive logistic regression. The ordinary logistic regression was unable to show any significant relation between magnesium level and post coronary artery bypass ...

Research paper thumbnail of The Association of Air Pollution and Emergency Medical Service Seeking

There are some reports on the association between air pollution and myocardial infarction, arrhyt... more There are some reports on the association between air pollution and myocardial infarction, arrhythmia, and mortality due to cardiac problems in susceptible individuals. We aimed to evaluate the association of air pollution and the emergency visits due to cardiovascular diseases, in a specialized heart hospital in Tehran.

Research paper thumbnail of Air Pollution and In-Hospital Mortality of Ischemic Heart Disease Patients

Journal of Biological Sciences, 2010

Research paper thumbnail of Efficacy of Double and Triple Phototherapy in Term Newborns With Hyperbilirubinemia: The First Clinical Trial

Pediatrics and Neonatology, 2009

Background: Icterus is the most common medical problem in neonates and phototherapy is the standa... more Background: Icterus is the most common medical problem in neonates and phototherapy is the standard treatment for neonatal hyperbilirubinemia. This study aimed to compare the efficacy and length of hospital stay of double and triple phototherapy in newborns with indirect hyperbilirubinemia. Methods: In a clinical trial, 40 healthy term newborns (gestational age > 37 weeks) with bilirubin ≥ 12 and ≥ 15 mg/dL in the second and third day, respectively, were randomly assigned to triple (n = 20) or double phototherapy (n = 20) groups. Total and direct serum bilirubin were measured at admission, 8, 16, and 24 hours after beginning of phototherapy, and every 12 hours thereafter until discharge (when bilirubin levels reached ≤ 10 mg/dL). Results: There were 21 male (52%) and 19 female (48%) term neonates, with significant difference between patients' age, weight, and age of icterus. There was no significant difference in the rate of bilirubin decline between the two groups within the first 8, 16 and 24 hours. There was no significant difference in mean length of hospital stay between the two groups. Analysis of complications showed no difference between triple and double groups. Conclusion: Triple phototherapy failed to reduce total serum bilirubin and shorten length of hospitalization more rapidly than double phototherapy.

Research paper thumbnail of ERYTHROCYTIC GLUCOSE6PHOSPHATE DEHYDROGENASE ACTIVITY IN DIABETIC PATIENTS

Background and objectives: Diabetes mellitus is a common and complicated disease. Studies imply b... more Background and objectives: Diabetes mellitus is a common and complicated disease. Studies imply blood glucose and its oxidant derivatives have a key role in pathogenesis of diabetes mellitus. Activity of enzyme "glucose-6-phosphate dehydrogenase" (G6PD), an anti-oxidant system, is important in preventing its complications. Unsuitable control of blood glucose decreases G6PD activity and increases diabetes mellitus complications. This study evaluated the difference of G6PD activity among diabetic and non diabetic patients, and the impact of hyperglycemia on the G6PD activity. Methodology: One hundred diabetic and one hundred non diabetic subjects were selected from patients 30 to 60 years old. Demographic data including gender, age, height, weight, duration of diabetes mellitus, type and duration of treatment, medical history (especially favism) were recorded. Blood pressure and body mass index were also measured. One blood sample was taken from each subject and 5 elements including G6PD presence and activity, fasting plasma glucose, plasma triglyceride and plasma high density lipoprotein were measured. Results: G6PD activity was significantly higher in non diabetic subjects (P<0.01). Within diabetics, G6PD mean activity was significantly higher in non dyslipidemic group (P<0.05) and in subjects with BMI < 25 (P<0.05). G6PD mean activity was significantly higher in non diabetics than dyslipidemic (P<0.01) and non dyslipidemic diabetics (P<0.05). Conclusion: Diabetic hyperglycemia may lead to serious complications and decrease G6PD activity. This issue itself aggravates diabetic injury due to inappropriate antioxidation process. Simultaneous dyslipidemia and obesity may intensify the effect of hyperglycemia and oxidative stress.

Research paper thumbnail of Prevalence of Cardiac Manifestations in HIV-Infected Patients in Iran

Jaids-journal of Acquired Immune Deficiency Syndromes, 2010

... Azar Hadadi, MD*. Sina Moradband Badie, MD†. Maryam Rohamm, MD‡. Mehrnaz Rasoolinejad, MD§. N... more ... Azar Hadadi, MD*. Sina Moradband Badie, MD†. Maryam Rohamm, MD‡. Mehrnaz Rasoolinejad, MD§. Nahid Mirzaee, MD‡. Reza Hamidian, MD*. *Sina Hospital. †Amir Alam Hospital. ‡Imam Khomeini Hospital. Tehran University of Medical Sciences, Tehran, Iran. ...

Research paper thumbnail of Family history of cardiovascular disease as a risk factor for coronary artery disease in adult offspring

Monaldi Arch Chest …, 2008

Background and aims: There is controversy about the role of positive family history as an indepen... more Background and aims: There is controversy about the role of positive family history as an independent risk factor for coronary artery disease. The aim of this work was to investigate the influence of family history on presentation of coronary artery disease in adult offspring, and on its severity.