Rita Driggers - Academia.edu (original) (raw)

Papers by Rita Driggers

Open Journal of Obstetrics and Gynecology, 2017

Diabetes Technology & Therapeutics, Jun 1, 2013

The safest and most effective way of treating gestational diabetes mellitus (GDM) is still being ... more The safest and most effective way of treating gestational diabetes mellitus (GDM) is still being investigated. Insulin has always been the first line in treatment since it does not cross the placenta. Recently, increasing studies have come out supporting the use of second-generation sulfonylureas for effective glycemic control. Preliminary studies indicated that glyburide is equal to insulin in achieving glycemic control but

Obstetrics & Gynecology, Dec 1, 2005

... Alexandra Bageris, MD Department of Obstetrics and Gynecology, Boston Medical Center, Boston,... more ... Alexandra Bageris, MD Department of Obstetrics and Gynecology, Boston Medical Center, Boston, Massachusetts ... Ultrasound Obstet Gynecol 2005;2:1604. 3. Vimercati A, Greco P, Kardashi A, Rossi C, Loizzi V, Scioscia M, et al. ...

Obstetric Anesthesia Digest, Sep 1, 2014

Obstetrics & Gynecology, Jun 1, 2015

To estimate whether cell-free DNA is present in nonviable pregnancies and thus can be used in dia... more To estimate whether cell-free DNA is present in nonviable pregnancies and thus can be used in diagnostic evaluation in this setting. We conducted a prospective cohort study of 50 participants at MedStar Washington Hospital Center, Washington, DC, between June 2013 and January 2014. Included were women with pregnancies complicated by missed abortion or fetal demise. All gestational ages were considered for study participation. Participants with fetal demise were offered the standard workup for fetal death per the American College of Obstetricians and Gynecologists. Maternal blood samples were processed to determine the presence of cell-free DNA, the corresponding fetal fractions, and genetic abnormalities. Fifty samples from nonviable pregnancies were analyzed. The average clinical gestational age was 16.9 weeks (standard deviation 9.2). The mean maternal body mass index was 30.3 (standard deviation 9.1). Seventy-six percent (38/50) of samples yielded cell-free DNA results, that is, had fetal fractions within the detectable range of 3.7-65%. Among the 38, 76% (29) were classified as euploid, 21% (8) as trisomies, and 3% (1) as microdeletion. A cell-free DNA result was obtained more frequently at ultrasonographic gestational ages of 8 weeks or greater compared with less than 8 weeks (87.9% [n=29/33, 95% confidence interval (CI) 72.7-95.2; and 52.9%, n=9/17, 95% CI 31.0-73.8] of the time, respectively, P=.012). Time from demise was not associated with obtaining a result. Among nonviable pregnancies, cell-free DNA is present in the maternal plasma with fetal fractions greater than 3.7% in more than three fourths of cases after an ultrasonographic gestational age of 8 weeks. ClinicalTrials.gov, www.clinicaltrials.gov, NCT01916928. III.

American Journal of Perinatology, May 21, 2020

Clinical Obstetrics and Gynecology, Mar 1, 2018

Journal of pediatric neurology, 2017

Infection during pregnancy is common and the developing fetal brain is vulnerable to vertical tra... more Infection during pregnancy is common and the developing fetal brain is vulnerable to vertical transmission due to immaturity of the fetal immune system. Infection is a major cause of multiple organ abnormalities, including the neuraxis, due to the neurotropism of the infectious agents. This review sets out to give an overview of fetal infection, review the general principles of the nature and timing of the infectious insult with respect to outcomes, review the neuroimaging of infection by ultrasound and magnetic resonance imaging (MRI), and review the various pathogens involved, including the two most common, cytomegalovirus (CMV) and Toxoplasma , and also other common viral and nonviral infections.

Immunohematology, 2020

Views expressed in this article are those of the author and do not reflect the official policy or... more Views expressed in this article are those of the author and do not reflect the official policy or position of the Department of the Navy, Department of Defense, or U.S. Government. The only previously published case of anti-G in a pregnant woman indicated that anti-G alone caused little, if any, fetal or neonatal hemolysis. This report describes an affected fetus with amnionitic fluid OD 450 absorbance values in the moderate zone of the Liley prediction graph who required prolonged phototherapy after birth until day of life 20. Anti-G was identified and anti-C and -D excluded in the mother’s serum. In contrast to the previous report, this report shows anti-G alone can cause moderate HDN and that fetal monitoring and treatment may be necessary. Immunohematology 2006;22:166–170.

Obstetrics & Gynecology International Journal, 2015

The Journal of reproductive medicine, 1998

Management of thyroid cancer in pregnancy is controversial, as evidenced by disagreement in recom... more Management of thyroid cancer in pregnancy is controversial, as evidenced by disagreement in recommendations cited in leading obstetrics textbooks. Most thyroid carcinomas are well differentiated and pursue an indolent course. Many physicians recommend delay in surgical therapy until after delivery because of operative morbidity. A 27-year-old primigravida was found to have a solitary thyroid nodule at her initial obstetrics appointment. Fine needle aspiration was consistent with papillary carcinoma. Although detected at 8 weeks' estimated gestational age (EGA), the decision was made to defer surgical therapy until postpartum. The patient was referred to a tertiary care facility at 24 weeks' EGA secondary to rapid growth of the nodule. Surgery performed at that time revealed invasive disease. Review of the literature suggests that delay in definitive therapy stems from early reports of fetal loss related to surgery, but contemporary data suggest that the risk of fetal loss re...

Obstet Gynecol

... La utilizacio´n del cepillo se ha asociado a unas tasas más bajas de muestras inadecuadas, au... more ... La utilizacio´n del cepillo se ha asociado a unas tasas más bajas de muestras inadecuadas, aunque Klam et al.40 no lograron detectar ninguna diferencia significativa entre ambos mé todos; sen alaron que la tasa de inadecuacio´ n disminuıa con el paso del tiempo, lo que ...

MMWR. Morbidity and mortality weekly report, Jan 20, 2017

CDC has updated its interim guidance for U.S. health care providers caring for infants with possi... more CDC has updated its interim guidance for U.S. health care providers caring for infants with possible congenital Zika virus infection (1) in response to recently published updated guidance for health care providers caring for pregnant women with possible Zika virus exposure (2), unknown sensitivity and specificity of currently available diagnostic tests for congenital Zika virus infection, and recognition of additional clinical findings associated with congenital Zika virus infection. All infants born to mothers with possible Zika virus exposure* during pregnancy should receive a standard evaluation at birth and at each subsequent well-child visit including a comprehensive physical examination, age-appropriate vision screening and developmental monitoring and screening using validated tools (3-5), and newborn hearing screen at birth, preferably using auditory brainstem response (ABR) methodology (6). Specific guidance for laboratory testing and clinical evaluation are provided for th...

Clinical Case Reports, 2018

This is an open access article under the terms of the Creative Commons Attribution License, which... more This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

American journal of obstetrics and gynecology, 2018

Ultrasound imaging has become integral to the practice of obstetrics and gynecology. With increas... more Ultrasound imaging has become integral to the practice of obstetrics and gynecology. With increasing educational demands and limited hours in residency programs, dedicated time for training and achieving competency in ultrasound has diminished substantially. The American Institute of Ultrasound in Medicine assembled a multisociety task force to develop a consensus-based, standardized curriculum and competency assessment tools for obstetric and gynecologic ultrasound training in residency programs. The curriculum and competency assessment tools were developed based on existing national and international guidelines for the performance of obstetric and gynecologic ultrasound examinations and thus are intended to represent the minimum requirement for such training. By expert consensus, the curriculum was developed for each year of training, criteria for each competency assessment image were generated, the pass score was established at, or close to, 75% for each, and obtaining a set of 5...

American journal of perinatology, Mar 24, 2017

To examine labor induction by race/ethnicity and factors associated with disparity in induction.... more To examine labor induction by race/ethnicity and factors associated with disparity in induction. This is a retrospective cohort study of 143,634 women eligible for induction ≥24 weeks' gestation from 12 clinical centers (2002-2008). Rates of labor induction for each racial/ethnic group were calculated and stratified by gestational age intervals: early preterm (24-33), late preterm (34-36), and term (37-41weeks). Multivariable logistic regression examined the association between maternal race/ethnicity and induction controlling for maternal characteristics and pregnancy complications. The primary outcome was rate of induction by race/ethnicity. Inductions that were indicated, non-medically indicated, or without recorded indication were also compared. Non-Hispanic black (NHB) women had the highest percentage rate of induction, 44.6% ( < 0.001). After adjustment, all racial/ethnic groups had lower odds of induction compared with non-Hispanic white (NHW) women. At term, NHW wo...

Data Revues 00029378 V206i1ss S0002937811018011, Dec 29, 2011

The New England journal of medicine, Jan 30, 2016

The current outbreak of Zika virus (ZIKV) infection has been associated with an apparent increase... more The current outbreak of Zika virus (ZIKV) infection has been associated with an apparent increased risk of congenital microcephaly. We describe a case of a pregnant woman and her fetus infected with ZIKV during the 11th gestational week. The fetal head circumference decreased from the 47th percentile to the 24th percentile between 16 and 20 weeks of gestation. ZIKV RNA was identified in maternal serum at 16 and 21 weeks of gestation. At 19 and 20 weeks of gestation, substantial brain abnormalities were detected on ultrasonography and magnetic resonance imaging (MRI) without the presence of microcephaly or intracranial calcifications. On postmortem analysis of the fetal brain, diffuse cerebral cortical thinning, high ZIKV RNA loads, and viral particles were detected, and ZIKV was subsequently isolated.