Robert Mazzoli - Academia.edu (original) (raw)

Papers by Robert Mazzoli

Research paper thumbnail of Anophthalmic Socket and Orbital Implants

Radiologic Clinics of North America, 1998

ABSTRACT

Research paper thumbnail of Eye Injuries From Merchandise Display Hooks

American Journal of Ophthalmology, Sep 30, 1995

Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise displa... more Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise display hooks. Ocular and periocular injuries from display hooks include conjunctival, eyelid, and canalicular lacerations, as well as penetrating brain injury. Display hooks are commonly used in retail establishments and pose a high risk when placed below eye level.

Research paper thumbnail of Use of self-expanding, hydrophilic osmotic expanders (hydrogel) in the reconstruction of congenital clinical anophthalmos

Current Opinion in Ophthalmology, Oct 1, 2004

PURPOSE OF REVIEW: Rehabilitation of the congenitally anophthalmic orbit is frustrating to both t... more PURPOSE OF REVIEW: Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and physician. Traditional methods involve using progressively enlarging static acrylic conformers to expand the conjunctival socket, followed by placement of conventional static spherical orbital implants, dermis-fat grafts, or inflatable balloon expanders for orbital enlargement. Limitations of these methods typically result in less-than-optimal cosmetic outcomes, with retardation of bony orbital and overlying soft tissue growth adversely affecting midfacial growth and symmetry. Recent advances in tissue expansion technology may offer additional, novel alternatives to conventional therapies.RECENT FINDINGS: Hydrogel tissue expanders were recently adapted for use in congenital anophthalmia. The expanders are placed in their dry, contracted states, and expand gradually to their full size via osmosis of surrounding tissue fluid, with up to a 10-fold increase in volume. Offering the benefit of predictable and controllable self-expansion, hydrogel expanders may offer yet another alternative or adjunctive therapy to the early rehabilitation of the contracted socket. Separate appliances are used for conjunctival and orbital reconstruction. Initial results appear promising. Tempering the enthusiasm for their use, however-particularly in terms of implanted orbital expanders-is the recent spate of long-term complications reported from previous uses of hydrogels as scleral buckling material.SUMMARY: Self-expanding hydrogel tissue expanders appear to offer an intriguing reconstructive alternative to the frustrating condition of congenital anophthalmia. Long-term safety of the material as an orbital implant has not yet been demonstrated, but early results are promising.

Research paper thumbnail of Characteristics of Okihiro syndrome

Journal of Pediatric Ophthalmology and Strabismus, 2001

To describe Okihiro syndrome, a syndrome consisting of Duane's syndrome, radial ray anoma... more To describe Okihiro syndrome, a syndrome consisting of Duane's syndrome, radial ray anomaly, and sensorineural deafness. The incidence of anomalies in 41 individuals from 9 affected families was assessed by literature review and patient examination, and the frequency of the characteristics occurring together was determined. Of all the individuals with at least one of the above characteristics, only 12% had all three characteristics. However, 44% had both Duane's syndrome and radial ray anomaly, whereas sensorineural deafness alone occurred in only 17% of patients. Okihiro syndrome is consistent with autosomal dominance with variable penetrance, manifesting primarily with Duane's syndrome and radial ray anomaly, and less frequently, sensorineural deafness.

Research paper thumbnail of The use of rigid eye shields (Fox shields) at the point of injury for ocular trauma in Afghanistan

The journal of trauma and acute care surgery, 2014

Unlike hemorrhagic injuries in which direct pressure is indicated, any pressure placed on the eye... more Unlike hemorrhagic injuries in which direct pressure is indicated, any pressure placed on the eye after penetrating trauma can significantly worsen the injury by expulsing intraocular contents. The accepted first response measure for obvious or suspected penetrating ocular injury is placement of a rigid shield that vaults the eye so as to prevent accidental iatrogenic aggravation during transport to the ophthalmologist. Patching and placing intervening gauze between the shield and the eye are both contraindicated. Anecdotally, compliance with these recommendations is poor in the military and civilian communities alike; however, published studies documenting compliance are uniformly lacking. This study was undertaken to provide such an evaluation. In this retrospective observational study, the Department of Defense Trauma Registry was reviewed to identify eye injuries in Afghanistan from 2010 to 2012 and to examine compliance with eye shield recommendations. One hundred fifty-seven r...

Research paper thumbnail of Subperiosteal hematoma in multiple settings

Digital journal of ophthalmology : DJO / sponsored by Massachusetts Eye and Ear Infirmary, 2013

Most reports of orbital hemorrhage do not distinguish among intraconal, extraconal, and subperios... more Most reports of orbital hemorrhage do not distinguish among intraconal, extraconal, and subperiosteal hemorrhages, although several reports describe isolated subperiosteal hematomas as a separate entity. We report 3 cases of subperiosteal hematoma with different etiologies but similar progression of signs and symptoms. Each patient presented with spontaneous proptosis, rarely caused by orbital subperiosteal hematoma, measuring approximately 5 mm. Over the course of 4-10 days their conditions worsened and warranted intervention. All 3 cases were treated with anterior orbitotomy, and visual acuity returned to baseline following surgery in all.

Research paper thumbnail of Pediatric PRK (PhotoRefractive Keratectomy) with Mitomycin C (MCC) for Persistent Anisometropic Amblyopia. A Case Report

Binocular vision & strabology quarterly, Simms-Romano's, 2012

To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) f... more To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) for the treatment of severe pediatric anisometropia and amblyopia resistant to more conservative treatment modalities. A 3 year-old-child, who at 18 months old underwent unilateral diode laser treatment for threshold ROP, developed 11 diopters of anisometropic myopia and secondary dense amblyopia of the Right Eye. Only after all conservative treatment options failed was he treated with PRK and MMC. Principal outcome measures included cycloplegic refraction, the amount of refractive correction, degree of corneal haze and change in visual acuity. On presentation: BCVA: 20/CF OD; 20/30 OS. CRNS: -11.50 diopters sphere OD; -0.50 diopters sphere OS. Unilateral PRK followed by application of MMC (0.2 mg/ml) for 1 min was performed under general anesthesia. Three-month postoperative findings include: VA: 20/30 OD; 20/25 OS. CRNS: +0.25 diopters sphere OD. At one year, the BCVA remained equal at ...

Research paper thumbnail of Dominant familial congenital entropion with tarsal hypoplasia and atrichosis

Ophthalmic plastic and reconstructive surgery, 2002

Congenital entropion and atrichosis of the lower eyelids associated with tarsal hypoplasia is a r... more Congenital entropion and atrichosis of the lower eyelids associated with tarsal hypoplasia is a rare condition, with isolated reports in the literature and without previous pathologic examination. Case report. A father and son with mild entropion, lower eyelash atrichosis, and tarsal hypoplasia are described. A family pedigree demonstrates autosomal dominant inheritance. Histopathology from an entropion repair shows rudimentary tarsus and Meibomian glands consistent with hypoplasia of the tarsus. Isolated congenital entropion may occur in association with atrichosis of the lower eyelashes and hypoplasia of the tarsus as an isolated anomaly. The condition may be inherited as an autosomal dominant trait and appears to be well tolerated.

Research paper thumbnail of Monocanalicular intubation for dacryostenosis in oculo-auriculo-vertebral dysplasia (hemifacial microsomia) with congenital corneal anesthesia

Ophthalmic plastic and reconstructive surgery, 2000

To present a case of oculo-auriculo-vertebral dysplasia associated with corneal anesthesia and ip... more To present a case of oculo-auriculo-vertebral dysplasia associated with corneal anesthesia and ipsilateral dacryostenosis that was successfully treated with monocanalicular lacrimal intubation. Case report. Previous neurotrophic corneal ulcers in a child with hemifacial microsomia had become secondarily infected from a stagnant tear lake, resulting in significant corneal scarring and visual loss. A single monocanalicular stent maintained nasolacrimal patency without causing further corneal trauma, despite constant medial gaze because of wide lateral tarsorrhaphy and contralateral occlusion therapy for amblyopia. Monocanalicular stents may aid the treatment of dacryostenosis in the face of compromised corneal sensation.

Research paper thumbnail of Eye Injuries From Merchandise Display Hooks

American Journal of Ophthalmology, 1995

Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise displa... more Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise display hooks. Ocular and periocular injuries from display hooks include conjunctival, eyelid, and canalicular lacerations, as well as penetrating brain injury. Display hooks are commonly used in retail establishments and pose a high risk when placed below eye level.

Research paper thumbnail of Spitting Cobra Ophthalmia in United Nations Forces in Somalia

American Journal of Ophthalmology, 1994

RefDoc Bienvenue - Welcome. Refdoc est un service / is powered by. ...

Research paper thumbnail of Cutaneous Benign Mixed Tumor (Chondroid Syringoma) of the Eyelid: Clinical Presentation and Management

Ophthalmic Plastic & Reconstructive Surgery, 2004

To describe the clinical presentation of cutaneous benign mixed tumor of the eyelid and its manag... more To describe the clinical presentation of cutaneous benign mixed tumor of the eyelid and its management options. Periocular cases of cutaneous benign mixed tumor were gathered from members of an oculoplastics specialty Internet discussion group. A total of 9 patients are described in this retrospective, interventional case series. The clinical presentation, histopathology, and management of these lesions is reviewed. Patients were typically asymptomatic, presenting with a slowly enlarging, nontender nodule of 2 to 8 years' duration. The lesions ranged from 4 mm to 17 mm in greatest dimension. Four of the lesions were on the eyelid margin, three in the sub-brow area of the upper eyelid, and two in the central lids. All six cases not involving the brow were fixed to the tarsus; one brow lesion was believed to be adherent to the skin. None of the lesions was associated with significant changes of the overlying epidermis, although one lesion showed overlying pigmentation. All patients underwent excisional biopsy for diagnostic or cosmetic reasons. On histopathologic examination, the tumors were biphasic, with an epithelial component exhibiting apocrine or hair follicle differentiation and a myxoid, adipocytic, chondroid, and/or fibrous stroma. The pathologic diagnoses were all consistent with cutaneous benign mixed tumor (chondroid syringoma, pleomorphic adenoma). Follow-up ranged from 2 weeks to 12 months, although several patients failed to keep scheduled follow-up appointments. No clinical recurrences were identified. Cutaneous benign mixed tumor may occur in the eyelid, and, although uncommon, should be included in the differential diagnosis of firm, nodular eyelid tumors. The histopathologic features are similar to those seen in this tumor type arising in other areas of the body. Preoperative consideration of this diagnostic possibility may allow the surgeon to plan for complete excision, thereby reducing the possibility of recurrence or malignant transformation.

Research paper thumbnail of Ocular Blast Injuries in Mass-Casualty Incidents

Ophthalmology, 2014

Purpose: To report the ocular injuries sustained by survivors of the April 15, 2013, Boston Marat... more Purpose: To report the ocular injuries sustained by survivors of the April 15, 2013, Boston Marathon bombing and the April 17, 2013, fertilizer plant explosion in West, Texas. Design: Multicenter, cross-sectional, retrospective, comparative case series. Participants: Seventy-two eyes of 36 patients treated at 12 institutions were included in the study. Methods: Ocular and systemic trauma data were collected from medical records. Main Outcome Measures: Types and severity of ocular and systemic trauma and associations with mechanisms of injury.

Research paper thumbnail of Benign Mixed Tumor Arising from an Accessory Lacrimal Gland of Wolfring

Ophthalmic Plastic & Reconstructive Surgery, 1995

We report a 59-year-old man who had a slowly enlarging mass of the central upper eyelid that prov... more We report a 59-year-old man who had a slowly enlarging mass of the central upper eyelid that proved histopathologically to be a benign mixed tumor (pleomorphic adenoma) arising from an accessory lacrimal gland of Wolfring. The tumor was totally separate from the main lacrimal gland, and its deep location in the lid excluded origin from dermal sweat glands. Benign mixed tumors of the accessory lacrimal glands are exceedingly rare tumors of the ocular adnexa.

Research paper thumbnail of Suggested Precautions When Using a Monocanalicular Stent

Ophthalmic Plastic and Reconstructive Surgery, 2001

... Hospital Lariboisiere Paris; Paris, France. Fondation A. de Rothschild Paris; Paris, France. ... more ... Hospital Lariboisiere Paris; Paris, France. Fondation A. de Rothschild Paris; Paris, France. To the Editor: ... Tarif Hurbli MD. Gilles Renard MD. Jean-Marc Ruban MD. Emmanuel Racy MD. JeanAntoine Bernard MD. ... REFERENCES. 1. Mazzoli RA, Raymond WR, Ainbinder DJ, et al. ...

Research paper thumbnail of Analysis of anterior and posterior corneal curvature changes using Orbscan technology in radial keratotomy eyes exposed to hypoxia

Journal of Cataract & Refractive Surgery, 2002

To study the changes in anterior and posterior corneal curvatures in radial keratotomy (RK) and n... more To study the changes in anterior and posterior corneal curvatures in radial keratotomy (RK) and normal eyes exposed to hypoxia using Orbscan (Bausch & Lomb) technology. Department of Ophthalmology, Madigan Army Medical Center, Tacoma, Washington, USA. At sea level, 11 RK subjects and 10 control subjects were exposed to ocular surface hypoxia in 1 eye by filtering humidified, compressed 100% nitrogen (0% oxygen) through an airtight goggle system for 2 hours. The contralateral eye was exposed to humidified, compressed air (21% oxygen) simultaneously through the airtight goggle system. Orbscan analysis was performed in each subject before and immediately after gas exposure. This analysis included measurement of the anterior axial and posterior axial corneal curvatures as well as corneal pachymetry. In the RK eyes exposed to 100% nitrogen gas, there was a statistically significant flattening in the anterior axial corneal curvature (P = .0012) and in the posterior axial corneal curvature (P = .0067). Radial keratotomy and control eyes exposed to air and control eyes exposed to 100% nitrogen gas demonstrated no statistically significant change in the anterior axial or posterior axial corneal curvature. Corneal hypoxia induced a statistically significant flattening in the anterior axial and posterior axial corneal curvatures in eyes that had had RK. There was no significant change in these curvatures in RK eyes exposed to air and in control eyes exposed to air or 100% nitrogen gas.

Research paper thumbnail of Gaze-evoked amaurosis: a report of five cases

Ophthalmology, 2003

To highlight the various causes of gaze-evoked amaurosis.

Research paper thumbnail of Virtual reality simulation in acquiring and differentiating basic ophthalmic microsurgical skills

Simulation in healthcare : journal of the Society for Simulation in Healthcare, 2009

A virtual reality (VR) surgical simulator (EyeSi ophthalmosurgical simulator: VRMagic, Mannheim, ... more A virtual reality (VR) surgical simulator (EyeSi ophthalmosurgical simulator: VRMagic, Mannheim, Germany) was evaluated as a part-task training platform for differentiating and developing basic ophthalmic microsurgical skills.

Research paper thumbnail of Use of self-expanding, hydrophilic osmotic expanders (hydrogel) in the reconstruction of congenital clinical anophthalmos

Current Opinion in Ophthalmology, 2004

Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and phys... more Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and physician. Traditional methods involve using progressively enlarging static acrylic conformers to expand the conjunctival socket, followed by placement of conventional static spherical orbital implants, dermis-fat grafts, or inflatable balloon expanders for orbital enlargement. Limitations of these methods typically result in less-than-optimal cosmetic outcomes, with retardation of bony orbital and overlying soft tissue growth adversely affecting midfacial growth and symmetry. Recent advances in tissue expansion technology may offer additional, novel alternatives to conventional therapies. Hydrogel tissue expanders were recently adapted for use in congenital anophthalmia. The expanders are placed in their dry, contracted states, and expand gradually to their full size via osmosis of surrounding tissue fluid, with up to a 10-fold increase in volume. Offering the benefit of predictable and controllable self-expansion, hydrogel expanders may offer yet another alternative or adjunctive therapy to the early rehabilitation of the contracted socket. Separate appliances are used for conjunctival and orbital reconstruction. Initial results appear promising. Tempering the enthusiasm for their use, however-particularly in terms of implanted orbital expanders-is the recent spate of long-term complications reported from previous uses of hydrogels as scleral buckling material. Self-expanding hydrogel tissue expanders appear to offer an intriguing reconstructive alternative to the frustrating condition of congenital anophthalmia. Long-term safety of the material as an orbital implant has not yet been demonstrated, but early results are promising.

Research paper thumbnail of The diagnosis and management of orbital blowout fractures: Update 2001

The American Journal of Emergency Medicine, 2001

A cogent update of orbital blowout history, anatomy, and management are included with a retrospec... more A cogent update of orbital blowout history, anatomy, and management are included with a retrospective study of 59 pure orbital blowout fractures which occurred between 1994 and 1998. Our goal is to provide a better understanding of this frequently encountered entity and to help augment the confidence of nonophthalmologists who will often evaluate patients with suspected orbital blowout fractures. (Am J Emerg Med 2001;19:147-154. This is a US Government work. There are no restrictions on its use.)

Research paper thumbnail of Anophthalmic Socket and Orbital Implants

Radiologic Clinics of North America, 1998

ABSTRACT

Research paper thumbnail of Eye Injuries From Merchandise Display Hooks

American Journal of Ophthalmology, Sep 30, 1995

Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise displa... more Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise display hooks. Ocular and periocular injuries from display hooks include conjunctival, eyelid, and canalicular lacerations, as well as penetrating brain injury. Display hooks are commonly used in retail establishments and pose a high risk when placed below eye level.

Research paper thumbnail of Use of self-expanding, hydrophilic osmotic expanders (hydrogel) in the reconstruction of congenital clinical anophthalmos

Current Opinion in Ophthalmology, Oct 1, 2004

PURPOSE OF REVIEW: Rehabilitation of the congenitally anophthalmic orbit is frustrating to both t... more PURPOSE OF REVIEW: Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and physician. Traditional methods involve using progressively enlarging static acrylic conformers to expand the conjunctival socket, followed by placement of conventional static spherical orbital implants, dermis-fat grafts, or inflatable balloon expanders for orbital enlargement. Limitations of these methods typically result in less-than-optimal cosmetic outcomes, with retardation of bony orbital and overlying soft tissue growth adversely affecting midfacial growth and symmetry. Recent advances in tissue expansion technology may offer additional, novel alternatives to conventional therapies.RECENT FINDINGS: Hydrogel tissue expanders were recently adapted for use in congenital anophthalmia. The expanders are placed in their dry, contracted states, and expand gradually to their full size via osmosis of surrounding tissue fluid, with up to a 10-fold increase in volume. Offering the benefit of predictable and controllable self-expansion, hydrogel expanders may offer yet another alternative or adjunctive therapy to the early rehabilitation of the contracted socket. Separate appliances are used for conjunctival and orbital reconstruction. Initial results appear promising. Tempering the enthusiasm for their use, however-particularly in terms of implanted orbital expanders-is the recent spate of long-term complications reported from previous uses of hydrogels as scleral buckling material.SUMMARY: Self-expanding hydrogel tissue expanders appear to offer an intriguing reconstructive alternative to the frustrating condition of congenital anophthalmia. Long-term safety of the material as an orbital implant has not yet been demonstrated, but early results are promising.

Research paper thumbnail of Characteristics of Okihiro syndrome

Journal of Pediatric Ophthalmology and Strabismus, 2001

To describe Okihiro syndrome, a syndrome consisting of Duane's syndrome, radial ray anoma... more To describe Okihiro syndrome, a syndrome consisting of Duane's syndrome, radial ray anomaly, and sensorineural deafness. The incidence of anomalies in 41 individuals from 9 affected families was assessed by literature review and patient examination, and the frequency of the characteristics occurring together was determined. Of all the individuals with at least one of the above characteristics, only 12% had all three characteristics. However, 44% had both Duane's syndrome and radial ray anomaly, whereas sensorineural deafness alone occurred in only 17% of patients. Okihiro syndrome is consistent with autosomal dominance with variable penetrance, manifesting primarily with Duane's syndrome and radial ray anomaly, and less frequently, sensorineural deafness.

Research paper thumbnail of The use of rigid eye shields (Fox shields) at the point of injury for ocular trauma in Afghanistan

The journal of trauma and acute care surgery, 2014

Unlike hemorrhagic injuries in which direct pressure is indicated, any pressure placed on the eye... more Unlike hemorrhagic injuries in which direct pressure is indicated, any pressure placed on the eye after penetrating trauma can significantly worsen the injury by expulsing intraocular contents. The accepted first response measure for obvious or suspected penetrating ocular injury is placement of a rigid shield that vaults the eye so as to prevent accidental iatrogenic aggravation during transport to the ophthalmologist. Patching and placing intervening gauze between the shield and the eye are both contraindicated. Anecdotally, compliance with these recommendations is poor in the military and civilian communities alike; however, published studies documenting compliance are uniformly lacking. This study was undertaken to provide such an evaluation. In this retrospective observational study, the Department of Defense Trauma Registry was reviewed to identify eye injuries in Afghanistan from 2010 to 2012 and to examine compliance with eye shield recommendations. One hundred fifty-seven r...

Research paper thumbnail of Subperiosteal hematoma in multiple settings

Digital journal of ophthalmology : DJO / sponsored by Massachusetts Eye and Ear Infirmary, 2013

Most reports of orbital hemorrhage do not distinguish among intraconal, extraconal, and subperios... more Most reports of orbital hemorrhage do not distinguish among intraconal, extraconal, and subperiosteal hemorrhages, although several reports describe isolated subperiosteal hematomas as a separate entity. We report 3 cases of subperiosteal hematoma with different etiologies but similar progression of signs and symptoms. Each patient presented with spontaneous proptosis, rarely caused by orbital subperiosteal hematoma, measuring approximately 5 mm. Over the course of 4-10 days their conditions worsened and warranted intervention. All 3 cases were treated with anterior orbitotomy, and visual acuity returned to baseline following surgery in all.

Research paper thumbnail of Pediatric PRK (PhotoRefractive Keratectomy) with Mitomycin C (MCC) for Persistent Anisometropic Amblyopia. A Case Report

Binocular vision & strabology quarterly, Simms-Romano's, 2012

To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) f... more To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with Mitomycin C (MMC) for the treatment of severe pediatric anisometropia and amblyopia resistant to more conservative treatment modalities. A 3 year-old-child, who at 18 months old underwent unilateral diode laser treatment for threshold ROP, developed 11 diopters of anisometropic myopia and secondary dense amblyopia of the Right Eye. Only after all conservative treatment options failed was he treated with PRK and MMC. Principal outcome measures included cycloplegic refraction, the amount of refractive correction, degree of corneal haze and change in visual acuity. On presentation: BCVA: 20/CF OD; 20/30 OS. CRNS: -11.50 diopters sphere OD; -0.50 diopters sphere OS. Unilateral PRK followed by application of MMC (0.2 mg/ml) for 1 min was performed under general anesthesia. Three-month postoperative findings include: VA: 20/30 OD; 20/25 OS. CRNS: +0.25 diopters sphere OD. At one year, the BCVA remained equal at ...

Research paper thumbnail of Dominant familial congenital entropion with tarsal hypoplasia and atrichosis

Ophthalmic plastic and reconstructive surgery, 2002

Congenital entropion and atrichosis of the lower eyelids associated with tarsal hypoplasia is a r... more Congenital entropion and atrichosis of the lower eyelids associated with tarsal hypoplasia is a rare condition, with isolated reports in the literature and without previous pathologic examination. Case report. A father and son with mild entropion, lower eyelash atrichosis, and tarsal hypoplasia are described. A family pedigree demonstrates autosomal dominant inheritance. Histopathology from an entropion repair shows rudimentary tarsus and Meibomian glands consistent with hypoplasia of the tarsus. Isolated congenital entropion may occur in association with atrichosis of the lower eyelashes and hypoplasia of the tarsus as an isolated anomaly. The condition may be inherited as an autosomal dominant trait and appears to be well tolerated.

Research paper thumbnail of Monocanalicular intubation for dacryostenosis in oculo-auriculo-vertebral dysplasia (hemifacial microsomia) with congenital corneal anesthesia

Ophthalmic plastic and reconstructive surgery, 2000

To present a case of oculo-auriculo-vertebral dysplasia associated with corneal anesthesia and ip... more To present a case of oculo-auriculo-vertebral dysplasia associated with corneal anesthesia and ipsilateral dacryostenosis that was successfully treated with monocanalicular lacrimal intubation. Case report. Previous neurotrophic corneal ulcers in a child with hemifacial microsomia had become secondarily infected from a stagnant tear lake, resulting in significant corneal scarring and visual loss. A single monocanalicular stent maintained nasolacrimal patency without causing further corneal trauma, despite constant medial gaze because of wide lateral tarsorrhaphy and contralateral occlusion therapy for amblyopia. Monocanalicular stents may aid the treatment of dacryostenosis in the face of compromised corneal sensation.

Research paper thumbnail of Eye Injuries From Merchandise Display Hooks

American Journal of Ophthalmology, 1995

Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise displa... more Four patients had ocular or ocular adnexal injuries, which resulted from store merchandise display hooks. Ocular and periocular injuries from display hooks include conjunctival, eyelid, and canalicular lacerations, as well as penetrating brain injury. Display hooks are commonly used in retail establishments and pose a high risk when placed below eye level.

Research paper thumbnail of Spitting Cobra Ophthalmia in United Nations Forces in Somalia

American Journal of Ophthalmology, 1994

RefDoc Bienvenue - Welcome. Refdoc est un service / is powered by. ...

Research paper thumbnail of Cutaneous Benign Mixed Tumor (Chondroid Syringoma) of the Eyelid: Clinical Presentation and Management

Ophthalmic Plastic & Reconstructive Surgery, 2004

To describe the clinical presentation of cutaneous benign mixed tumor of the eyelid and its manag... more To describe the clinical presentation of cutaneous benign mixed tumor of the eyelid and its management options. Periocular cases of cutaneous benign mixed tumor were gathered from members of an oculoplastics specialty Internet discussion group. A total of 9 patients are described in this retrospective, interventional case series. The clinical presentation, histopathology, and management of these lesions is reviewed. Patients were typically asymptomatic, presenting with a slowly enlarging, nontender nodule of 2 to 8 years' duration. The lesions ranged from 4 mm to 17 mm in greatest dimension. Four of the lesions were on the eyelid margin, three in the sub-brow area of the upper eyelid, and two in the central lids. All six cases not involving the brow were fixed to the tarsus; one brow lesion was believed to be adherent to the skin. None of the lesions was associated with significant changes of the overlying epidermis, although one lesion showed overlying pigmentation. All patients underwent excisional biopsy for diagnostic or cosmetic reasons. On histopathologic examination, the tumors were biphasic, with an epithelial component exhibiting apocrine or hair follicle differentiation and a myxoid, adipocytic, chondroid, and/or fibrous stroma. The pathologic diagnoses were all consistent with cutaneous benign mixed tumor (chondroid syringoma, pleomorphic adenoma). Follow-up ranged from 2 weeks to 12 months, although several patients failed to keep scheduled follow-up appointments. No clinical recurrences were identified. Cutaneous benign mixed tumor may occur in the eyelid, and, although uncommon, should be included in the differential diagnosis of firm, nodular eyelid tumors. The histopathologic features are similar to those seen in this tumor type arising in other areas of the body. Preoperative consideration of this diagnostic possibility may allow the surgeon to plan for complete excision, thereby reducing the possibility of recurrence or malignant transformation.

Research paper thumbnail of Ocular Blast Injuries in Mass-Casualty Incidents

Ophthalmology, 2014

Purpose: To report the ocular injuries sustained by survivors of the April 15, 2013, Boston Marat... more Purpose: To report the ocular injuries sustained by survivors of the April 15, 2013, Boston Marathon bombing and the April 17, 2013, fertilizer plant explosion in West, Texas. Design: Multicenter, cross-sectional, retrospective, comparative case series. Participants: Seventy-two eyes of 36 patients treated at 12 institutions were included in the study. Methods: Ocular and systemic trauma data were collected from medical records. Main Outcome Measures: Types and severity of ocular and systemic trauma and associations with mechanisms of injury.

Research paper thumbnail of Benign Mixed Tumor Arising from an Accessory Lacrimal Gland of Wolfring

Ophthalmic Plastic & Reconstructive Surgery, 1995

We report a 59-year-old man who had a slowly enlarging mass of the central upper eyelid that prov... more We report a 59-year-old man who had a slowly enlarging mass of the central upper eyelid that proved histopathologically to be a benign mixed tumor (pleomorphic adenoma) arising from an accessory lacrimal gland of Wolfring. The tumor was totally separate from the main lacrimal gland, and its deep location in the lid excluded origin from dermal sweat glands. Benign mixed tumors of the accessory lacrimal glands are exceedingly rare tumors of the ocular adnexa.

Research paper thumbnail of Suggested Precautions When Using a Monocanalicular Stent

Ophthalmic Plastic and Reconstructive Surgery, 2001

... Hospital Lariboisiere Paris; Paris, France. Fondation A. de Rothschild Paris; Paris, France. ... more ... Hospital Lariboisiere Paris; Paris, France. Fondation A. de Rothschild Paris; Paris, France. To the Editor: ... Tarif Hurbli MD. Gilles Renard MD. Jean-Marc Ruban MD. Emmanuel Racy MD. JeanAntoine Bernard MD. ... REFERENCES. 1. Mazzoli RA, Raymond WR, Ainbinder DJ, et al. ...

Research paper thumbnail of Analysis of anterior and posterior corneal curvature changes using Orbscan technology in radial keratotomy eyes exposed to hypoxia

Journal of Cataract & Refractive Surgery, 2002

To study the changes in anterior and posterior corneal curvatures in radial keratotomy (RK) and n... more To study the changes in anterior and posterior corneal curvatures in radial keratotomy (RK) and normal eyes exposed to hypoxia using Orbscan (Bausch & Lomb) technology. Department of Ophthalmology, Madigan Army Medical Center, Tacoma, Washington, USA. At sea level, 11 RK subjects and 10 control subjects were exposed to ocular surface hypoxia in 1 eye by filtering humidified, compressed 100% nitrogen (0% oxygen) through an airtight goggle system for 2 hours. The contralateral eye was exposed to humidified, compressed air (21% oxygen) simultaneously through the airtight goggle system. Orbscan analysis was performed in each subject before and immediately after gas exposure. This analysis included measurement of the anterior axial and posterior axial corneal curvatures as well as corneal pachymetry. In the RK eyes exposed to 100% nitrogen gas, there was a statistically significant flattening in the anterior axial corneal curvature (P = .0012) and in the posterior axial corneal curvature (P = .0067). Radial keratotomy and control eyes exposed to air and control eyes exposed to 100% nitrogen gas demonstrated no statistically significant change in the anterior axial or posterior axial corneal curvature. Corneal hypoxia induced a statistically significant flattening in the anterior axial and posterior axial corneal curvatures in eyes that had had RK. There was no significant change in these curvatures in RK eyes exposed to air and in control eyes exposed to air or 100% nitrogen gas.

Research paper thumbnail of Gaze-evoked amaurosis: a report of five cases

Ophthalmology, 2003

To highlight the various causes of gaze-evoked amaurosis.

Research paper thumbnail of Virtual reality simulation in acquiring and differentiating basic ophthalmic microsurgical skills

Simulation in healthcare : journal of the Society for Simulation in Healthcare, 2009

A virtual reality (VR) surgical simulator (EyeSi ophthalmosurgical simulator: VRMagic, Mannheim, ... more A virtual reality (VR) surgical simulator (EyeSi ophthalmosurgical simulator: VRMagic, Mannheim, Germany) was evaluated as a part-task training platform for differentiating and developing basic ophthalmic microsurgical skills.

Research paper thumbnail of Use of self-expanding, hydrophilic osmotic expanders (hydrogel) in the reconstruction of congenital clinical anophthalmos

Current Opinion in Ophthalmology, 2004

Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and phys... more Rehabilitation of the congenitally anophthalmic orbit is frustrating to both the parents and physician. Traditional methods involve using progressively enlarging static acrylic conformers to expand the conjunctival socket, followed by placement of conventional static spherical orbital implants, dermis-fat grafts, or inflatable balloon expanders for orbital enlargement. Limitations of these methods typically result in less-than-optimal cosmetic outcomes, with retardation of bony orbital and overlying soft tissue growth adversely affecting midfacial growth and symmetry. Recent advances in tissue expansion technology may offer additional, novel alternatives to conventional therapies. Hydrogel tissue expanders were recently adapted for use in congenital anophthalmia. The expanders are placed in their dry, contracted states, and expand gradually to their full size via osmosis of surrounding tissue fluid, with up to a 10-fold increase in volume. Offering the benefit of predictable and controllable self-expansion, hydrogel expanders may offer yet another alternative or adjunctive therapy to the early rehabilitation of the contracted socket. Separate appliances are used for conjunctival and orbital reconstruction. Initial results appear promising. Tempering the enthusiasm for their use, however-particularly in terms of implanted orbital expanders-is the recent spate of long-term complications reported from previous uses of hydrogels as scleral buckling material. Self-expanding hydrogel tissue expanders appear to offer an intriguing reconstructive alternative to the frustrating condition of congenital anophthalmia. Long-term safety of the material as an orbital implant has not yet been demonstrated, but early results are promising.

Research paper thumbnail of The diagnosis and management of orbital blowout fractures: Update 2001

The American Journal of Emergency Medicine, 2001

A cogent update of orbital blowout history, anatomy, and management are included with a retrospec... more A cogent update of orbital blowout history, anatomy, and management are included with a retrospective study of 59 pure orbital blowout fractures which occurred between 1994 and 1998. Our goal is to provide a better understanding of this frequently encountered entity and to help augment the confidence of nonophthalmologists who will often evaluate patients with suspected orbital blowout fractures. (Am J Emerg Med 2001;19:147-154. This is a US Government work. There are no restrictions on its use.)