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Papers by Roberto Stefini

Research paper thumbnail of Surgical Resolution of Trigeminal Neuralgia Due to Intra-Axial Compression by Pontine Cavernous Angioma

World Neurosurgery, Oct 1, 2010

Research paper thumbnail of Automated end-to-side anastomosis to the middle cerebral artery with C-Port xA: A feasibility study on human cadavers

Asian journal of neurosurgery, Jun 1, 2013

Research paper thumbnail of Ruptured Aneurysm in Sphenoid Sinus: Which Is the Best Treatment

Case Reports in Neurology, 2013

Research paper thumbnail of Large Vestibular Scwannoma in The Jugular Foramen

Research paper thumbnail of Management of Antithrombotic Drugs in Patients with Isolated Traumatic Brain Injury: An Intersociety Consensus Document

Neurocritical Care, Apr 7, 2023

Research paper thumbnail of Relationship between lumbar lordosis, pelvic parameters, PI-LL mismatch and outcome after short fusion surgery for lumbar degenerative disease. Literature review, rational and presentation of public study protocol: RELApSE study (registry for evaluation of lumbar arthrodesis sagittal alignEment)

Research paper thumbnail of Surgery of Cerebral Ischemia: State of the Art for the Supratentorial Region

Current Innovations in Medicine and Medical Science Vol. 4

Research paper thumbnail of Posterior fossa syndrome in a population of children and young adults with medulloblastoma: a retrospective, multicenter Italian study on incidence and pathophysiology in a histologically homogeneous and consecutive series of 136 patients

Journal of Neuro-Oncology

Research paper thumbnail of Impact of a posttraumatic cerebral infarction on outcome in patients with TBI: the Italian multicenter cohort INCEPT study

Critical Care, 2020

Background Post-traumatic cerebral infarction (PTCI) is common after traumatic brain injury (TBI)... more Background Post-traumatic cerebral infarction (PTCI) is common after traumatic brain injury (TBI). It is unclear what the occurrence of a PTCI is, how it impacts the long-term outcome, and whether it adds incremental prognostic value to established outcome predictors. Methods This was a prospective multicenter cohort study of moderate and severe TBI patients. The primary objective was to evaluate if PTCI was an independent risk factor for the 6-month outcome assessed with the Glasgow Outcome Scale (GOS). We also assessed the PTCI occurrence and if it adds incremental value to the International Mission for Prognosis and Clinical Trial design in TBI (IMPACT) core and extended models. Results We enrolled 143 patients, of whom 47 (32.9%) developed a PTCI. In the multiple ordered logistic regression, PTCI was retained in both the core and extended IMPACT models as an independent predictor of the GOS. The predictive performances increased significantly when PTCI was added to the IMPACT co...

Research paper thumbnail of A Survey on Pituitary Surgery in Italy

Research paper thumbnail of Stereotactic Radiosurgery with Gamma Knife in Recurrent Rathke's Cleft Cyst: Case Report and Literature Analysis

PubMed, Jul 23, 2022

Background: Rathke's cleft cyst is a benign expansive lesion of the sella turcica. If related to ... more Background: Rathke's cleft cyst is a benign expansive lesion of the sella turcica. If related to clinical disorders, the patient needs surgical treatment. Objective: To demonstrate the efficacy of radiosurgery in the treatment of relapse of Rathke's cleft cyst as an alternative to surgery. Methods and material: The stereotactic radiosurgical treatment was performed at the Gamma Knife Center of the Niguarda Hospital in a patient with Rathke's cleft cyst subjected to two subsequent neurosurgical resections with early regrowth of the cyst. The cyst underwent radiosurgery with a prescription dose of 12 Gy at 50% (minimum dose 9.8, mean 17.3 and maximum 24.4). Results: Three years after stereotactic radiosurgical treatment the patient is asymptomatic and does not present disorders of the hypothalamic-pituitary axis or further visual alterations. The control MRI shows a reduction of the cyst's volume. Conclusions: Stereotactic radiosurgery resulted in a reduction of the cyst's volume and avoided further recourse to surgery.

Research paper thumbnail of From Reparative Surgery to Regenerative Surgery: State of the Art of Porous Hydroxyapatite in Cranioplasty

International Journal of Molecular Sciences, May 13, 2022

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Towards a common language in neurosurgical outcome evaluation: the NEON (NEurosurgical Outcome Network) proposal

Journal of Neurosurgical Sciences

Research paper thumbnail of Right gyrus cinguli low-grade astrocytoma recurrence removed through a contralateral transfalcine approach with a 4K-3D exoscope

Chinese Neurosurgical Journal

Background Brain tumor surgery has been using operative microscope for years. Recently, thanks to... more Background Brain tumor surgery has been using operative microscope for years. Recently, thanks to developments in surgical technology with procedures performed on head-up displays, exoscopes have been introduced as an alternative to microscopic vision. Case presentation We present a case of a 46-year-old patient with a low-grade glioma recurrence of the right gyrus cinguli removed with a contralateral transfalcine approach using an exoscope (ORBEYE 4K-three-dimensional (3D) exoscope, Sony Olympus Medical Solutions Inc., Tokyo, Japan). The operating room setup for this approach is illustrated. During the procedure, the surgeon was seated with head and back in an upright position, while the camera was aligned with the surgical corridor. The exoscope provided detailed, high-quality 4K-3D images of the anatomical structures and optimal depth perception, making surgery accurate and precise. At the end of the resection, an intraoperative MRI scan showed complete removal of the lesion. The...

Research paper thumbnail of Shifting from the directly observation via eyepiece lens to the monitor viewing of the surgical field: a new era for the microsurgery in neurosurgery

Journal of Neurosurgical Sciences, 2021

Research paper thumbnail of Stereotactic Radiosurgery with Gamma Knife in Recurrent Rathke's Cleft Cyst: Case Report and Literature Analysis

Neurology India, Jul 23, 2022

Research paper thumbnail of The efficacy of laser interstitial thermal therapy in the management of spinal metastases: a systematic review of the literature

Research paper thumbnail of Large Vestibular Scwannoma in The Jugular Foramen

Research paper thumbnail of Review Article Acute Supratentorial Ischemic Stroke: When Surgery Is Mandatory

Copyright © 2014 Gabriele Ronchetti et al. This is an open access article distributed under the C... more Copyright © 2014 Gabriele Ronchetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acute occlusion of middle cerebral artery (MCA) leads to severe brain swelling and to a malignant, often fatal syndrome. The authors summarize the current knowledge about such a condition and review the main surgical issues involved. Decompressive hemicraniectomy keeps being a valid option in accurately selected patients. 1.

Research paper thumbnail of Meningiomas in the canyon: The choice between subcranial trans frontal sinus (TfSA) and endonasal approach (EEa)

Objective: The aim of this study is to present our surgical experience in removal of anterior fos... more Objective: The aim of this study is to present our surgical experience in removal of anterior fossa midline meningiomas (AmM) using the EEa or the TfSa and underline surgical criterias and technical advantages based on anatomical considerations. Method: 54 patients with AmM underwent surgery with[for full text, please go to the a.m. URL]

Research paper thumbnail of Surgical Resolution of Trigeminal Neuralgia Due to Intra-Axial Compression by Pontine Cavernous Angioma

World Neurosurgery, Oct 1, 2010

Research paper thumbnail of Automated end-to-side anastomosis to the middle cerebral artery with C-Port xA: A feasibility study on human cadavers

Asian journal of neurosurgery, Jun 1, 2013

Research paper thumbnail of Ruptured Aneurysm in Sphenoid Sinus: Which Is the Best Treatment

Case Reports in Neurology, 2013

Research paper thumbnail of Large Vestibular Scwannoma in The Jugular Foramen

Research paper thumbnail of Management of Antithrombotic Drugs in Patients with Isolated Traumatic Brain Injury: An Intersociety Consensus Document

Neurocritical Care, Apr 7, 2023

Research paper thumbnail of Relationship between lumbar lordosis, pelvic parameters, PI-LL mismatch and outcome after short fusion surgery for lumbar degenerative disease. Literature review, rational and presentation of public study protocol: RELApSE study (registry for evaluation of lumbar arthrodesis sagittal alignEment)

Research paper thumbnail of Surgery of Cerebral Ischemia: State of the Art for the Supratentorial Region

Current Innovations in Medicine and Medical Science Vol. 4

Research paper thumbnail of Posterior fossa syndrome in a population of children and young adults with medulloblastoma: a retrospective, multicenter Italian study on incidence and pathophysiology in a histologically homogeneous and consecutive series of 136 patients

Journal of Neuro-Oncology

Research paper thumbnail of Impact of a posttraumatic cerebral infarction on outcome in patients with TBI: the Italian multicenter cohort INCEPT study

Critical Care, 2020

Background Post-traumatic cerebral infarction (PTCI) is common after traumatic brain injury (TBI)... more Background Post-traumatic cerebral infarction (PTCI) is common after traumatic brain injury (TBI). It is unclear what the occurrence of a PTCI is, how it impacts the long-term outcome, and whether it adds incremental prognostic value to established outcome predictors. Methods This was a prospective multicenter cohort study of moderate and severe TBI patients. The primary objective was to evaluate if PTCI was an independent risk factor for the 6-month outcome assessed with the Glasgow Outcome Scale (GOS). We also assessed the PTCI occurrence and if it adds incremental value to the International Mission for Prognosis and Clinical Trial design in TBI (IMPACT) core and extended models. Results We enrolled 143 patients, of whom 47 (32.9%) developed a PTCI. In the multiple ordered logistic regression, PTCI was retained in both the core and extended IMPACT models as an independent predictor of the GOS. The predictive performances increased significantly when PTCI was added to the IMPACT co...

Research paper thumbnail of A Survey on Pituitary Surgery in Italy

Research paper thumbnail of Stereotactic Radiosurgery with Gamma Knife in Recurrent Rathke's Cleft Cyst: Case Report and Literature Analysis

PubMed, Jul 23, 2022

Background: Rathke's cleft cyst is a benign expansive lesion of the sella turcica. If related to ... more Background: Rathke's cleft cyst is a benign expansive lesion of the sella turcica. If related to clinical disorders, the patient needs surgical treatment. Objective: To demonstrate the efficacy of radiosurgery in the treatment of relapse of Rathke's cleft cyst as an alternative to surgery. Methods and material: The stereotactic radiosurgical treatment was performed at the Gamma Knife Center of the Niguarda Hospital in a patient with Rathke's cleft cyst subjected to two subsequent neurosurgical resections with early regrowth of the cyst. The cyst underwent radiosurgery with a prescription dose of 12 Gy at 50% (minimum dose 9.8, mean 17.3 and maximum 24.4). Results: Three years after stereotactic radiosurgical treatment the patient is asymptomatic and does not present disorders of the hypothalamic-pituitary axis or further visual alterations. The control MRI shows a reduction of the cyst's volume. Conclusions: Stereotactic radiosurgery resulted in a reduction of the cyst's volume and avoided further recourse to surgery.

Research paper thumbnail of From Reparative Surgery to Regenerative Surgery: State of the Art of Porous Hydroxyapatite in Cranioplasty

International Journal of Molecular Sciences, May 13, 2022

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY

Research paper thumbnail of Towards a common language in neurosurgical outcome evaluation: the NEON (NEurosurgical Outcome Network) proposal

Journal of Neurosurgical Sciences

Research paper thumbnail of Right gyrus cinguli low-grade astrocytoma recurrence removed through a contralateral transfalcine approach with a 4K-3D exoscope

Chinese Neurosurgical Journal

Background Brain tumor surgery has been using operative microscope for years. Recently, thanks to... more Background Brain tumor surgery has been using operative microscope for years. Recently, thanks to developments in surgical technology with procedures performed on head-up displays, exoscopes have been introduced as an alternative to microscopic vision. Case presentation We present a case of a 46-year-old patient with a low-grade glioma recurrence of the right gyrus cinguli removed with a contralateral transfalcine approach using an exoscope (ORBEYE 4K-three-dimensional (3D) exoscope, Sony Olympus Medical Solutions Inc., Tokyo, Japan). The operating room setup for this approach is illustrated. During the procedure, the surgeon was seated with head and back in an upright position, while the camera was aligned with the surgical corridor. The exoscope provided detailed, high-quality 4K-3D images of the anatomical structures and optimal depth perception, making surgery accurate and precise. At the end of the resection, an intraoperative MRI scan showed complete removal of the lesion. The...

Research paper thumbnail of Shifting from the directly observation via eyepiece lens to the monitor viewing of the surgical field: a new era for the microsurgery in neurosurgery

Journal of Neurosurgical Sciences, 2021

Research paper thumbnail of Stereotactic Radiosurgery with Gamma Knife in Recurrent Rathke's Cleft Cyst: Case Report and Literature Analysis

Neurology India, Jul 23, 2022

Research paper thumbnail of The efficacy of laser interstitial thermal therapy in the management of spinal metastases: a systematic review of the literature

Research paper thumbnail of Large Vestibular Scwannoma in The Jugular Foramen

Research paper thumbnail of Review Article Acute Supratentorial Ischemic Stroke: When Surgery Is Mandatory

Copyright © 2014 Gabriele Ronchetti et al. This is an open access article distributed under the C... more Copyright © 2014 Gabriele Ronchetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Acute occlusion of middle cerebral artery (MCA) leads to severe brain swelling and to a malignant, often fatal syndrome. The authors summarize the current knowledge about such a condition and review the main surgical issues involved. Decompressive hemicraniectomy keeps being a valid option in accurately selected patients. 1.

Research paper thumbnail of Meningiomas in the canyon: The choice between subcranial trans frontal sinus (TfSA) and endonasal approach (EEa)

Objective: The aim of this study is to present our surgical experience in removal of anterior fos... more Objective: The aim of this study is to present our surgical experience in removal of anterior fossa midline meningiomas (AmM) using the EEa or the TfSa and underline surgical criterias and technical advantages based on anatomical considerations. Method: 54 patients with AmM underwent surgery with[for full text, please go to the a.m. URL]