Roberto Tramarin - Academia.edu (original) (raw)
Papers by Roberto Tramarin
The ISYDE project. A survey on Cardiac Re- habilitation in Italy. S. Urbinati, F. Fattirolli, R. ... more The ISYDE project. A survey on Cardiac Re- habilitation in Italy. S. Urbinati, F. Fattirolli, R. Tramarin, C. Chieffo, P. Temporelli, R. Griffo, R. Belardinelli, P. Vaghi, L. Briolotti per il Gruppo Italiano di Cardiologia Riabilitati- va e Preventiva (GICR). In 2001-2002 the Italian Working Group on Cardiac Rehabilitation (CR) developed the ISYDE project, a sur- vey on CR in
A new test (VITTORIO Test) for functional fitness assessment in rehabilitation after cardiac surg... more A new test (VITTORIO Test) for functional fitness assessment in rehabilitation after cardiac surgery. G. Calsamiglia, F. Camera, A. Mazza, P. Villa, F. Gigli Berzolari, R. Tramarin, F. Cobelli. An adequate assessment of physical function (PF) in Cardiac Rehabilitation (CR) plays a central role in early de- tection of physical limitations. Traditionally exercise toler- ance has been used as an
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo
Deep vein thrombosis is a potential complication in patients admitted to cardiac rehabilitation p... more Deep vein thrombosis is a potential complication in patients admitted to cardiac rehabilitation programs after acute coronary syndromes, episodes of acute congestive heart failure, and cardiac revascularization. A common clinical problem in these patients is to decide whether to start or continue physical training or not, given the risk of pulmonary embolism. Until definite evidence becomes available, careful patient selection and inpatient supervision may avoid the a priori withdrawal of such an important core component of cardiac rehabilitation programs.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2009
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2002
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2002
Routine hospital psychological care must necessarily make use of a clinically reliable screening ... more Routine hospital psychological care must necessarily make use of a clinically reliable screening instrument for the identification of the patients to be referred for a clinical interview with a psychologist. This study compared two tests for the evaluation of anxiety and depression that are widely used in the hospital setting: the Hospital Anxiety and Depression Scale (HADS) and Form A-D, consisting of the State-Trait Anxiety Inventory (STAI-X1) for the evaluation of anxiety, and the Depression Questionnaire (DQ) for measuring depression. The aim of the study was to identify which of these instruments is the most suitable for screening a population admitted at in-hospital intensive rehabilitation using the clinical interview-based psychological evaluation as the gold standard. Both of the tests showed a concordance with the clinical opinion expressed by the psychologist, whose judgement was guided by the use of the validation study evaluation form. The analyses confirmed the good co...
The Italian Survey on Cardiac Rehabilitation - 2008 (ISYDE-2008). Part 3. National availability a... more The Italian Survey on Cardiac Rehabilitation - 2008 (ISYDE-2008). Part 3. National availability and organization of cardiac rehabilitation facilities. R. Tramarin, M. Ambrosetti, S. De Feo, M. Piepoli, C. Riccio, R. Griffo on behalf of the ISYDE-2008 Investigators. From January 28th to February 10th 2008, the Italian
Diabetes Research and Clinical Practice, 2015
Chronic heart failure Cardiopulmonary exercise testing a b s t r a c t Background: Using data fro... more Chronic heart failure Cardiopulmonary exercise testing a b s t r a c t Background: Using data from the Italian SurveY on carDiac rEhabilitation (ISYDE-2008), this study provides insight into the level of implementation of Cardiac Rehabilitation (CR) in patients with diabetes.
European Journal of Heart Failure Supplements, 2003
rhythm and 79% had no previous history of embolism. The TE was fatal in one case. Pts with TE had... more rhythm and 79% had no previous history of embolism. The TE was fatal in one case. Pts with TE had lower ejection fraction (p=0,04); more frequent left ventricle segmental wall motion disturbances (p=0,02); higher heart rate (p=0,04); higher systolic (p=0,01) and diastolic (0,0001) blood pressure; and more frequent previous TE (p=0,009). Comparing pts with versus without TE, we found no difference in regarding the occurrence of diabetes, dislipidaemia, tobacco, alcoholic consumption, liver or renal insufficiency, chronic venous insufficiency, neoplasms, or AF. Although we applied the international recommendations for anticoagulation in HF, we observed a high incidence of TE events. A significant number of pts with TE were on sinus rhythm. This fact could be in favour of expanding the present indications for anticoagulation in HF to certain subgroups of pts in sinus rhythm.
Multidisciplinary Respiratory Medicine, 2014
Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-... more Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-occurrence has important implications in mortality and other outcomes. Even the most recent guidelines do not reliably address clinical, prognostic, and therapeutic concerns due to the overlap of respiratory and cardiac diseases. Study objectives and design: In order to evaluate in the reality of clinical practice the epidemiology and the reciprocal impact of cardio-pulmonary comorbidity on the clinical management, diagnostic workup and treatment, 1,500 cardiac and 1,500 respiratory inpatients, admitted in acute and rehabilitation units, will be enrolled in a multicenter, nationwide, prospective observational study. For this purpose, each center will enroll at least 50 consecutive patients. At discharge, data analysis will be aimed at the definition of cardiac and pulmonary inpatient comorbidity prevalence, demographic characteristics, length of hospital stay, and risk factors, taking into account also procedures, pharmacological and non-pharmacological treatment, and follow up in patients with cardio-respiratory comorbidity. Conclusions: The purely observational design of the study aims to give new relevant information on the assessment and management of overlapping patients in real life clinical practice, and new insight for improvement and implementation of current guidelines on the management of individual diseases.
Guidelines for psychology activities in cardiac rehabilitation and prevention. Task Force for psy... more Guidelines for psychology activities in cardiac rehabilitation and prevention. Task Force for psychology activities in cardiac rehabilitation and prevention, Italian Work- ing Group on Cardiac Rehabilitation and Prevention (GICR) - Core Writing Group: M. Sommaruga, R. Tramarin (Chair- persons), E. Angelino, O. Bettinardi, M.A. Cauteruccio, M. Miglioretti, M. Monti, A. Pierobon, C. Sguazzin - Reviewers:
Journal of the American College of Cardiology, 2003
increases cardiac preload.
Journal of the American College of Cardiology, 1998
http://content.onlinejacc.org on the World Wide Web at:
Journal of the American College of Cardiology, 2002
Background: the LONFLITI+ 2 studies have established that in high risk subjects after long (10-12... more Background: the LONFLITI+ 2 studies have established that in high risk subjects after long (10-12 hours) flights the incidence of deep venous thrombosis (DVT) is between 4-6%. Methods: 400 subjects at high risk for DVT were randomisad into 4 groups to evaluate two ...
Journal of the American College of Cardiology, 2004
BACKGROUND Recent studies have shown that anemia is a common comorbid condition in patients with ... more BACKGROUND Recent studies have shown that anemia is a common comorbid condition in patients with chronic heart failure (CHF), suggesting an impact on history and prognosis. AIM To investigate the mechanisms of anemia in a series of consecutive anemic CHF patients and define a rational therapeutic approach. METHODS A series of 148 consecutive adult CHF pts with Hb <13 g/dL (males) or <12 g/dL (females) was studied. Potential responsible factors for anemia were investigated by evaluating endogenous erythropoietin (Epo) production, serum cytokines levels (TNFalpha and its soluble receptors, IL-6 and IL-1Ra), body iron status, and iron supply for erythropoiesis. RESULTS 105 pts (71%) had evidence of severe defective endogenous erythropoietin production, indicated by an observed/predicted log(serum Epo) ratio <0.8; 85 pts (57%) had low serum iron (mean value for men 105, for women 45 ng/mL; 61 (41%) had low transferrin saturation (mean value 22% for men and 23% for women) and 85 (57%) had increased levels for soluble transferrin receptor. Impaired iron supply to erythropoiesis, as indicated by low transferrin saturation and/or increased values for soluble transferrin receptor, was observed in 105 pts (71%). Elevated values for high sensitivity C-reactive protein (mean value 0.69 for men and 0.61 mg/dL for women) were found in 83 pts (56%), increased serum creatinine in 44 pts (30%), cytokines activation in 133 pts (90%). CONCLUSION Our findings demonstrate that the vast majority of anemic CHF pts shows evidence of blunted endogenous erythropoietin production and/or defective iron supply for erythropoiesis. Therefore, the assessment of serum erythropoietin and the evaluation of body iron status represent a rational approach to treatment of the individual patient: according to those physiopathologic findings in most instances, subcutaneous administration of recombinant human erythropoietin combined with iv iron would represent the optimal therapeutic approach.
Journal of the American College of Cardiology, 1995
Journal of Cardiovascular Magnetic Resonance, 2005
We compared contrast-enhanced MRI (CeMRI) with the most widely used imaging techniques for myocar... more We compared contrast-enhanced MRI (CeMRI) with the most widely used imaging techniques for myocardial infarct (MI) diagnosis, SPECT and Echo, in unselected patients with chronic coronary artery disease (CAD). Two blinded operators assessed scars on MRI, SPECT and Echo images using a 16-segments LV model. We studied 105 consecutive patients: 50 had Q-wave MI (Q-MI), 19 non Q-wave MI or rest angina (nonQ-MI/RA) and 36 effort angina (EA) history. CeMRI was positive, respectively, in 96%, 37%, and 6%, SPECT in 90%, 53%, and 44%, and Echo in 84%, 32%, and 28% of patients (within Q-MI: CeMRI vs. SPECT p < 0.03, vs. Echo p < 0.001; within EA CeMRI vs. SPECT and ECHO p < 0.001; all trends p < 0.001, pseudo r-square: 0.56 -0.75 for CeMRI, 0.18 -0.28 for SPECT and 0.23 -0.37 for Echo). CeMRI and SPECT agreed in 83 patients (79%); negative SPECT with 1 ± 0 segments subendocardial delayed enhancement (DE) was found in 4 (4%); negative CeMRI with 4 ± 3 segments perfusion defects in 18 (17%), 16 of whom were obese or showed LBB or sub-occlusion of related coronary. CeMRI and Echo agreed in 78 patients (75%); negative Echo with 2 ± 1 segments subendocardial DE was found in 13 (12%) and negative CeMRI with 11 ± 7 segments kinetic abnormalities in 14 (13%), in 10 confirmed by Cine-MRI. In Q-MI, CeMRI detects DE more frequently than perfusion defects and, especially, kinetic abnormalities are found by SPECT and Echo, respectively. CeMRI identifies small areas of DE also in some patients with nonQ-MI or RA but usually not in patients with EA. This biologically plausible decreasing trend is shown by CeMRI more clearly than by SPECT and Echo. Disagreement between CeMRI and SPECT or Echo may be reduced, but perhaps not fully eluded, performing dobutamine Echo and SPECT after maximal epicardial coronary dilatation.
Journal of Cardiothoracic and Vascular Anesthesia, 2011
The ISYDE project. A survey on Cardiac Re- habilitation in Italy. S. Urbinati, F. Fattirolli, R. ... more The ISYDE project. A survey on Cardiac Re- habilitation in Italy. S. Urbinati, F. Fattirolli, R. Tramarin, C. Chieffo, P. Temporelli, R. Griffo, R. Belardinelli, P. Vaghi, L. Briolotti per il Gruppo Italiano di Cardiologia Riabilitati- va e Preventiva (GICR). In 2001-2002 the Italian Working Group on Cardiac Rehabilitation (CR) developed the ISYDE project, a sur- vey on CR in
A new test (VITTORIO Test) for functional fitness assessment in rehabilitation after cardiac surg... more A new test (VITTORIO Test) for functional fitness assessment in rehabilitation after cardiac surgery. G. Calsamiglia, F. Camera, A. Mazza, P. Villa, F. Gigli Berzolari, R. Tramarin, F. Cobelli. An adequate assessment of physical function (PF) in Cardiac Rehabilitation (CR) plays a central role in early de- tection of physical limitations. Traditionally exercise toler- ance has been used as an
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo
Deep vein thrombosis is a potential complication in patients admitted to cardiac rehabilitation p... more Deep vein thrombosis is a potential complication in patients admitted to cardiac rehabilitation programs after acute coronary syndromes, episodes of acute congestive heart failure, and cardiac revascularization. A common clinical problem in these patients is to decide whether to start or continue physical training or not, given the risk of pulmonary embolism. Until definite evidence becomes available, careful patient selection and inpatient supervision may avoid the a priori withdrawal of such an important core component of cardiac rehabilitation programs.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2009
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2002
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2002
Routine hospital psychological care must necessarily make use of a clinically reliable screening ... more Routine hospital psychological care must necessarily make use of a clinically reliable screening instrument for the identification of the patients to be referred for a clinical interview with a psychologist. This study compared two tests for the evaluation of anxiety and depression that are widely used in the hospital setting: the Hospital Anxiety and Depression Scale (HADS) and Form A-D, consisting of the State-Trait Anxiety Inventory (STAI-X1) for the evaluation of anxiety, and the Depression Questionnaire (DQ) for measuring depression. The aim of the study was to identify which of these instruments is the most suitable for screening a population admitted at in-hospital intensive rehabilitation using the clinical interview-based psychological evaluation as the gold standard. Both of the tests showed a concordance with the clinical opinion expressed by the psychologist, whose judgement was guided by the use of the validation study evaluation form. The analyses confirmed the good co...
The Italian Survey on Cardiac Rehabilitation - 2008 (ISYDE-2008). Part 3. National availability a... more The Italian Survey on Cardiac Rehabilitation - 2008 (ISYDE-2008). Part 3. National availability and organization of cardiac rehabilitation facilities. R. Tramarin, M. Ambrosetti, S. De Feo, M. Piepoli, C. Riccio, R. Griffo on behalf of the ISYDE-2008 Investigators. From January 28th to February 10th 2008, the Italian
Diabetes Research and Clinical Practice, 2015
Chronic heart failure Cardiopulmonary exercise testing a b s t r a c t Background: Using data fro... more Chronic heart failure Cardiopulmonary exercise testing a b s t r a c t Background: Using data from the Italian SurveY on carDiac rEhabilitation (ISYDE-2008), this study provides insight into the level of implementation of Cardiac Rehabilitation (CR) in patients with diabetes.
European Journal of Heart Failure Supplements, 2003
rhythm and 79% had no previous history of embolism. The TE was fatal in one case. Pts with TE had... more rhythm and 79% had no previous history of embolism. The TE was fatal in one case. Pts with TE had lower ejection fraction (p=0,04); more frequent left ventricle segmental wall motion disturbances (p=0,02); higher heart rate (p=0,04); higher systolic (p=0,01) and diastolic (0,0001) blood pressure; and more frequent previous TE (p=0,009). Comparing pts with versus without TE, we found no difference in regarding the occurrence of diabetes, dislipidaemia, tobacco, alcoholic consumption, liver or renal insufficiency, chronic venous insufficiency, neoplasms, or AF. Although we applied the international recommendations for anticoagulation in HF, we observed a high incidence of TE events. A significant number of pts with TE were on sinus rhythm. This fact could be in favour of expanding the present indications for anticoagulation in HF to certain subgroups of pts in sinus rhythm.
Multidisciplinary Respiratory Medicine, 2014
Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-... more Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-occurrence has important implications in mortality and other outcomes. Even the most recent guidelines do not reliably address clinical, prognostic, and therapeutic concerns due to the overlap of respiratory and cardiac diseases. Study objectives and design: In order to evaluate in the reality of clinical practice the epidemiology and the reciprocal impact of cardio-pulmonary comorbidity on the clinical management, diagnostic workup and treatment, 1,500 cardiac and 1,500 respiratory inpatients, admitted in acute and rehabilitation units, will be enrolled in a multicenter, nationwide, prospective observational study. For this purpose, each center will enroll at least 50 consecutive patients. At discharge, data analysis will be aimed at the definition of cardiac and pulmonary inpatient comorbidity prevalence, demographic characteristics, length of hospital stay, and risk factors, taking into account also procedures, pharmacological and non-pharmacological treatment, and follow up in patients with cardio-respiratory comorbidity. Conclusions: The purely observational design of the study aims to give new relevant information on the assessment and management of overlapping patients in real life clinical practice, and new insight for improvement and implementation of current guidelines on the management of individual diseases.
Guidelines for psychology activities in cardiac rehabilitation and prevention. Task Force for psy... more Guidelines for psychology activities in cardiac rehabilitation and prevention. Task Force for psychology activities in cardiac rehabilitation and prevention, Italian Work- ing Group on Cardiac Rehabilitation and Prevention (GICR) - Core Writing Group: M. Sommaruga, R. Tramarin (Chair- persons), E. Angelino, O. Bettinardi, M.A. Cauteruccio, M. Miglioretti, M. Monti, A. Pierobon, C. Sguazzin - Reviewers:
Journal of the American College of Cardiology, 2003
increases cardiac preload.
Journal of the American College of Cardiology, 1998
http://content.onlinejacc.org on the World Wide Web at:
Journal of the American College of Cardiology, 2002
Background: the LONFLITI+ 2 studies have established that in high risk subjects after long (10-12... more Background: the LONFLITI+ 2 studies have established that in high risk subjects after long (10-12 hours) flights the incidence of deep venous thrombosis (DVT) is between 4-6%. Methods: 400 subjects at high risk for DVT were randomisad into 4 groups to evaluate two ...
Journal of the American College of Cardiology, 2004
BACKGROUND Recent studies have shown that anemia is a common comorbid condition in patients with ... more BACKGROUND Recent studies have shown that anemia is a common comorbid condition in patients with chronic heart failure (CHF), suggesting an impact on history and prognosis. AIM To investigate the mechanisms of anemia in a series of consecutive anemic CHF patients and define a rational therapeutic approach. METHODS A series of 148 consecutive adult CHF pts with Hb <13 g/dL (males) or <12 g/dL (females) was studied. Potential responsible factors for anemia were investigated by evaluating endogenous erythropoietin (Epo) production, serum cytokines levels (TNFalpha and its soluble receptors, IL-6 and IL-1Ra), body iron status, and iron supply for erythropoiesis. RESULTS 105 pts (71%) had evidence of severe defective endogenous erythropoietin production, indicated by an observed/predicted log(serum Epo) ratio <0.8; 85 pts (57%) had low serum iron (mean value for men 105, for women 45 ng/mL; 61 (41%) had low transferrin saturation (mean value 22% for men and 23% for women) and 85 (57%) had increased levels for soluble transferrin receptor. Impaired iron supply to erythropoiesis, as indicated by low transferrin saturation and/or increased values for soluble transferrin receptor, was observed in 105 pts (71%). Elevated values for high sensitivity C-reactive protein (mean value 0.69 for men and 0.61 mg/dL for women) were found in 83 pts (56%), increased serum creatinine in 44 pts (30%), cytokines activation in 133 pts (90%). CONCLUSION Our findings demonstrate that the vast majority of anemic CHF pts shows evidence of blunted endogenous erythropoietin production and/or defective iron supply for erythropoiesis. Therefore, the assessment of serum erythropoietin and the evaluation of body iron status represent a rational approach to treatment of the individual patient: according to those physiopathologic findings in most instances, subcutaneous administration of recombinant human erythropoietin combined with iv iron would represent the optimal therapeutic approach.
Journal of the American College of Cardiology, 1995
Journal of Cardiovascular Magnetic Resonance, 2005
We compared contrast-enhanced MRI (CeMRI) with the most widely used imaging techniques for myocar... more We compared contrast-enhanced MRI (CeMRI) with the most widely used imaging techniques for myocardial infarct (MI) diagnosis, SPECT and Echo, in unselected patients with chronic coronary artery disease (CAD). Two blinded operators assessed scars on MRI, SPECT and Echo images using a 16-segments LV model. We studied 105 consecutive patients: 50 had Q-wave MI (Q-MI), 19 non Q-wave MI or rest angina (nonQ-MI/RA) and 36 effort angina (EA) history. CeMRI was positive, respectively, in 96%, 37%, and 6%, SPECT in 90%, 53%, and 44%, and Echo in 84%, 32%, and 28% of patients (within Q-MI: CeMRI vs. SPECT p < 0.03, vs. Echo p < 0.001; within EA CeMRI vs. SPECT and ECHO p < 0.001; all trends p < 0.001, pseudo r-square: 0.56 -0.75 for CeMRI, 0.18 -0.28 for SPECT and 0.23 -0.37 for Echo). CeMRI and SPECT agreed in 83 patients (79%); negative SPECT with 1 ± 0 segments subendocardial delayed enhancement (DE) was found in 4 (4%); negative CeMRI with 4 ± 3 segments perfusion defects in 18 (17%), 16 of whom were obese or showed LBB or sub-occlusion of related coronary. CeMRI and Echo agreed in 78 patients (75%); negative Echo with 2 ± 1 segments subendocardial DE was found in 13 (12%) and negative CeMRI with 11 ± 7 segments kinetic abnormalities in 14 (13%), in 10 confirmed by Cine-MRI. In Q-MI, CeMRI detects DE more frequently than perfusion defects and, especially, kinetic abnormalities are found by SPECT and Echo, respectively. CeMRI identifies small areas of DE also in some patients with nonQ-MI or RA but usually not in patients with EA. This biologically plausible decreasing trend is shown by CeMRI more clearly than by SPECT and Echo. Disagreement between CeMRI and SPECT or Echo may be reduced, but perhaps not fully eluded, performing dobutamine Echo and SPECT after maximal epicardial coronary dilatation.
Journal of Cardiothoracic and Vascular Anesthesia, 2011