Rodrigo Caceres - Academia.edu (original) (raw)
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Papers by Rodrigo Caceres
Developmental Cell, 2019
Highlights d MMPs accelerate but are not essential for invasion through basement membrane (BM) d ... more Highlights d MMPs accelerate but are not essential for invasion through basement membrane (BM) d In MMPÀ animals, a large protrusion breaches BM instead of invadopodia d Arp2/3-F-actin networks increase in density to allow BM breaching without MMPs d Mitochondria deliver more localized ATP for F-actin network growth without MMPs
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2015
Actin filament dynamics have been studied for decades in pure protein solutions or in cell extrac... more Actin filament dynamics have been studied for decades in pure protein solutions or in cell extracts, but a breakthrough in the field occurred at the turn of the century when it became possible to reconstitute networks of actin filaments, growing in a controlled but physiological manner on surfaces, mimicking the actin assembly that occurs at the plasma membrane during cell protrusion and cell shape changes. The story begins with the bacteria Listeria monocytogenes, the study of which led to the reconstitution of cellular actin polymerization on a variety of supports including plastic beads. These studies made possible the development of liposome-type substrates for filament assembly and micropatterning of actin polymerization nucleation. Based on the accumulated expertise of the last 15 years, many exciting approaches are being developed, including the addition of myosin to biomimetic actin networks to study the interplay between actin structure and contractility. The field is now poised to make artificial cells with a physiological and dynamic actin cytoskeleton, and subsequently to put these cells together to make in vitro tissues. This article is part of a Special Issue entitled: Mechanobiology.
IEEE Latin America Transactions, 2014
This article presents a comparative analysis of various indicators that evaluate the impact of a ... more This article presents a comparative analysis of various indicators that evaluate the impact of a distributed generator (DG) connection in a power distribution system. The goal is to select indicators to have an effective tool for studying and selecting alternatives for size and location of the DG. This analysis is performed on the IEEE 33 test system, considering mean and hourly values for power generation and load demand.
Developmental Cell, 2019
Highlights d MMPs accelerate but are not essential for invasion through basement membrane (BM) d ... more Highlights d MMPs accelerate but are not essential for invasion through basement membrane (BM) d In MMPÀ animals, a large protrusion breaches BM instead of invadopodia d Arp2/3-F-actin networks increase in density to allow BM breaching without MMPs d Mitochondria deliver more localized ATP for F-actin network growth without MMPs
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2015
Actin filament dynamics have been studied for decades in pure protein solutions or in cell extrac... more Actin filament dynamics have been studied for decades in pure protein solutions or in cell extracts, but a breakthrough in the field occurred at the turn of the century when it became possible to reconstitute networks of actin filaments, growing in a controlled but physiological manner on surfaces, mimicking the actin assembly that occurs at the plasma membrane during cell protrusion and cell shape changes. The story begins with the bacteria Listeria monocytogenes, the study of which led to the reconstitution of cellular actin polymerization on a variety of supports including plastic beads. These studies made possible the development of liposome-type substrates for filament assembly and micropatterning of actin polymerization nucleation. Based on the accumulated expertise of the last 15 years, many exciting approaches are being developed, including the addition of myosin to biomimetic actin networks to study the interplay between actin structure and contractility. The field is now poised to make artificial cells with a physiological and dynamic actin cytoskeleton, and subsequently to put these cells together to make in vitro tissues. This article is part of a Special Issue entitled: Mechanobiology.
IEEE Latin America Transactions, 2014
This article presents a comparative analysis of various indicators that evaluate the impact of a ... more This article presents a comparative analysis of various indicators that evaluate the impact of a distributed generator (DG) connection in a power distribution system. The goal is to select indicators to have an effective tool for studying and selecting alternatives for size and location of the DG. This analysis is performed on the IEEE 33 test system, considering mean and hourly values for power generation and load demand.