Rohani Nayak - Academia.edu (original) (raw)

Papers by Rohani Nayak

Case Reports in Urology, 2015

Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosi... more Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. Most of the patients are diagnosed at an advanced stage and are with poor outcome. Radical nephrectomy is the mainstay of the treatment. We reported a case of squamous cell carcinoma of the kidney in a 50-year-old female who presented with the right sided abdomen pain. The patient was treated with radical nephrectomy.

Primary malignancy of the vagina is unusual and sarcoma as the primary is rarer. The majority of ... more Primary malignancy of the vagina is unusual and sarcoma as the primary is rarer. The majority of sarcomas are diagnosed at an advanced stage. Histopathological grade is the most important factor to predict the outcome. Surgical resection is the main stay of treatment. The role of adjuvant radiotherapy and chemotherapy is controversial. An adjuvant radiotherapy should be given in the case of high-grade tumors, and post-operative surgical margin positive cases. Neoadjuvant chemotherapy should be given in locally advanced cases to decrease the tumor burden to make a possible wide local excision with wider margin. We reported a case of spindle cell sarcoma of the vagina in a 57-year-old woman who was treated with 3 cycles of neoadjuvant chemotherapy followed by surgical resection with adequate margin, and doing well on 6 months follow-up.

Brenner tumors are the rare solid ovarian tumor, malignant variant being rarer. It commonly prese... more Brenner tumors are the rare solid ovarian tumor, malignant variant being rarer. It commonly presents with vaginal bleeding, a palpable pelvic mass, and pelvic pain. Mostly, it is unilateral with local dissemination and spreading beyond the pelvis to distant organs is rare. It closely resembles transitional cell carcinoma of urinary bladder. Optimal surgery in advanced disease and surgical staging in the early stage is the corner stone of management. We report a case of malignant Brenner tumor of the ovary in 70-year-old female treated with staging laparotomy followed by adjuvant chemotherapy and having no evidence of disease after 2 years follow-up.

Carcinosarcoma of ovary is also known as malignant mixed mullerian tumour. It is a very rare enti... more Carcinosarcoma of ovary is also known as malignant mixed mullerian tumour. It is a very rare entity and accounts for less than 1% of all ovarian tumour. It has overall worst survival and poor prognosis. Primary optimal cytoreductive debulking surgery is a crucial part of treatment. Adjuvant taxane and platinum based combination chemotherapy should be recommended after primary surgery. We report a case of carcinosarcoma of ovary treated with surgery followed by platinum and taxane based combination chemotherapy.

Journal of Cancer and Tumor International

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

Background: Eclampsia is an obstetric emergency complicating the maternal outcome in all developi... more Background: Eclampsia is an obstetric emergency complicating the maternal outcome in all developing countries. Various regimen of magnesium sulphate have been tried to treat the condition with varied results. A few studies have been done to compare between various types of regimen in this part of India. Magnesium sulphate is a double edged sword. Aim of the study was to compare the maternal morbidity and mortality after administering two different regimen of magnesium sulphate in eclampsia patients in a tertiary care hospital in Odisha. Methods: This is a randomized prospective study conducted at the Labour room, Dept of O and GSCB Medical College, Cuttack, Odisha over a period of 18 months (January 2015 to June 2016). 228 eclampsia patients were randomly selected out of which 114 were administered low dose (Dhaka) regimen and the other 114 subjects were given high dose (Pritchard) regimen. The findings were analysed using SPSS version 21. Results: In low dose regimen group convulsion was controlled in 96% of eclampsia patients and in only few cases recurrence of seizure occurred and was shifted to standard dose regimen. Conclusions: The toxicity profile also seems to be less so low dose regimen (Dhaka) can be adopted with less toxicity in peripheral hospitals with low resource setting.

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

With the conventional investigations like HSG, USG, Sonohysterogram and Sonosalpingography, abdom... more With the conventional investigations like HSG, USG, Sonohysterogram and Sonosalpingography, abdominopelvic adhesions, endometriosis and pelvic inflammations are missed. Even after bilateral free spillage found in the HSG, patient doesn't conceive. It is the normal pelvic anatomy which is the key factor for conception. The tubo-ovarian alignment is important for ovum pick up. Genital tuberculosis, one of the very important causes of infertility in India, is usually missed in HSG, but can be easily diagnosed with laparoscopy. 2 So our study intends to highlight the effectiveness of DTHL in evaluating female infertility.

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

Background: Birth asphyxia which results due to deprivation of oxygen to the foetus during the bi... more Background: Birth asphyxia which results due to deprivation of oxygen to the foetus during the birth process is still the leading cause of perinatal death. So the labour should be monitored by an effective method. Electronic foetal monitoring is quite promising in this regard. The present study was done to project the effectiveness of cardiotocography (CTG) at admission to labour room in high risk pregnancies as a predictor of perinatal outcome. Methods: This is a randomized prospective study conducted in the labour room of SCB Medical College, over a period of 1 year (April 2013 to April 2014) at Cuttack, Odisha, India. All women randomized for the study were subjected to initial admission CTG in the 1st stage of labour. Those with a normal/reassuring admission test, monitored by intermittent auscultation method and those with abnormal test were monitored by continuous CTG. Foetal and perinatal outcome were co-related with admission CTG. Results: Foetal distress during labour developed in 29 % of patients with a normal test and in 64% of patients with an abnormal test. The admission test had a sensitivity of 44% specificity 95% of and a positive predictive value of 50% for predicting an APGAR score 5 min after birth. Neonatal admission to SNCU was required in 29% of patients with a normal test and 45% of patients with an abnormal test. Conclusions: Labour admission CTG should be used for screening but not a sole diagnostic test of compromised foetus. It is found to be valuable in high risk pregnancy.

Journal of Cancer and Tumor International, 2016

Case Reports in Urology, 2015

Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosi... more Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. Most of the patients are diagnosed at an advanced stage and are with poor outcome. Radical nephrectomy is the mainstay of the treatment. We reported a case of squamous cell carcinoma of the kidney in a 50-year-old female who presented with the right sided abdomen pain. The patient was treated with radical nephrectomy.

Primary malignancy of the vagina is unusual and sarcoma as the primary is rarer. The majority of ... more Primary malignancy of the vagina is unusual and sarcoma as the primary is rarer. The majority of sarcomas are diagnosed at an advanced stage. Histopathological grade is the most important factor to predict the outcome. Surgical resection is the main stay of treatment. The role of adjuvant radiotherapy and chemotherapy is controversial. An adjuvant radiotherapy should be given in the case of high-grade tumors, and post-operative surgical margin positive cases. Neoadjuvant chemotherapy should be given in locally advanced cases to decrease the tumor burden to make a possible wide local excision with wider margin. We reported a case of spindle cell sarcoma of the vagina in a 57-year-old woman who was treated with 3 cycles of neoadjuvant chemotherapy followed by surgical resection with adequate margin, and doing well on 6 months follow-up.

Brenner tumors are the rare solid ovarian tumor, malignant variant being rarer. It commonly prese... more Brenner tumors are the rare solid ovarian tumor, malignant variant being rarer. It commonly presents with vaginal bleeding, a palpable pelvic mass, and pelvic pain. Mostly, it is unilateral with local dissemination and spreading beyond the pelvis to distant organs is rare. It closely resembles transitional cell carcinoma of urinary bladder. Optimal surgery in advanced disease and surgical staging in the early stage is the corner stone of management. We report a case of malignant Brenner tumor of the ovary in 70-year-old female treated with staging laparotomy followed by adjuvant chemotherapy and having no evidence of disease after 2 years follow-up.

Carcinosarcoma of ovary is also known as malignant mixed mullerian tumour. It is a very rare enti... more Carcinosarcoma of ovary is also known as malignant mixed mullerian tumour. It is a very rare entity and accounts for less than 1% of all ovarian tumour. It has overall worst survival and poor prognosis. Primary optimal cytoreductive debulking surgery is a crucial part of treatment. Adjuvant taxane and platinum based combination chemotherapy should be recommended after primary surgery. We report a case of carcinosarcoma of ovary treated with surgery followed by platinum and taxane based combination chemotherapy.

Journal of Cancer and Tumor International

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

Background: Eclampsia is an obstetric emergency complicating the maternal outcome in all developi... more Background: Eclampsia is an obstetric emergency complicating the maternal outcome in all developing countries. Various regimen of magnesium sulphate have been tried to treat the condition with varied results. A few studies have been done to compare between various types of regimen in this part of India. Magnesium sulphate is a double edged sword. Aim of the study was to compare the maternal morbidity and mortality after administering two different regimen of magnesium sulphate in eclampsia patients in a tertiary care hospital in Odisha. Methods: This is a randomized prospective study conducted at the Labour room, Dept of O and GSCB Medical College, Cuttack, Odisha over a period of 18 months (January 2015 to June 2016). 228 eclampsia patients were randomly selected out of which 114 were administered low dose (Dhaka) regimen and the other 114 subjects were given high dose (Pritchard) regimen. The findings were analysed using SPSS version 21. Results: In low dose regimen group convulsion was controlled in 96% of eclampsia patients and in only few cases recurrence of seizure occurred and was shifted to standard dose regimen. Conclusions: The toxicity profile also seems to be less so low dose regimen (Dhaka) can be adopted with less toxicity in peripheral hospitals with low resource setting.

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

With the conventional investigations like HSG, USG, Sonohysterogram and Sonosalpingography, abdom... more With the conventional investigations like HSG, USG, Sonohysterogram and Sonosalpingography, abdominopelvic adhesions, endometriosis and pelvic inflammations are missed. Even after bilateral free spillage found in the HSG, patient doesn't conceive. It is the normal pelvic anatomy which is the key factor for conception. The tubo-ovarian alignment is important for ovum pick up. Genital tuberculosis, one of the very important causes of infertility in India, is usually missed in HSG, but can be easily diagnosed with laparoscopy. 2 So our study intends to highlight the effectiveness of DTHL in evaluating female infertility.

International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 2016

Background: Birth asphyxia which results due to deprivation of oxygen to the foetus during the bi... more Background: Birth asphyxia which results due to deprivation of oxygen to the foetus during the birth process is still the leading cause of perinatal death. So the labour should be monitored by an effective method. Electronic foetal monitoring is quite promising in this regard. The present study was done to project the effectiveness of cardiotocography (CTG) at admission to labour room in high risk pregnancies as a predictor of perinatal outcome. Methods: This is a randomized prospective study conducted in the labour room of SCB Medical College, over a period of 1 year (April 2013 to April 2014) at Cuttack, Odisha, India. All women randomized for the study were subjected to initial admission CTG in the 1st stage of labour. Those with a normal/reassuring admission test, monitored by intermittent auscultation method and those with abnormal test were monitored by continuous CTG. Foetal and perinatal outcome were co-related with admission CTG. Results: Foetal distress during labour developed in 29 % of patients with a normal test and in 64% of patients with an abnormal test. The admission test had a sensitivity of 44% specificity 95% of and a positive predictive value of 50% for predicting an APGAR score 5 min after birth. Neonatal admission to SNCU was required in 29% of patients with a normal test and 45% of patients with an abnormal test. Conclusions: Labour admission CTG should be used for screening but not a sole diagnostic test of compromised foetus. It is found to be valuable in high risk pregnancy.

Journal of Cancer and Tumor International, 2016