Romeu Domingues - Academia.edu (original) (raw)

Papers by Romeu Domingues

ABSTRACT PURPOSE/AIM Congenital urinary lesions are typically best assessed with ultrasound (US).... more ABSTRACT PURPOSE/AIM Congenital urinary lesions are typically best assessed with ultrasound (US). MR imaging is an important adjunct method in the assessment of the fetal urinary pathologies. The purpose of this exhibit is to illustrate the most common MR findings in fetuses with urinary pathologies and to correlate these features with the prenatal US abnormalities. CONTENT ORGANIZATION - MR imaging protocol and normal anatomy patterns - Urinary lesions • Hydronephrosis and Pelvicaliectasis: ureteropelvic junction obstruction; posterior urethral valves; duplex kidneys • Renal agenesis • Ectopic Kidneys • Horseshoe kidney • Renal cystic diseases: multicystic dysplastic kidney, autosomal recessive polycystic kidney, isolated renal cyst • Prune-belly syndrome • Cloacal malformation SUMMARY • The MRI is a useful imaging technique for the evaluation of fetal urinary tract • The use of an adequate MRI protocol and the knowledge of the normal anatomy patters are key points when evaluating fetuses with urinary pathologies • In most of the urinary pathologies, the fetal MR imaging provides important findings that help defining the differential diagnosis • There is a good correlation between prenatal MR imaging and US in fetuses with urinary abnormalities

Rheumatology International, Jul 1, 2013

Relapsing polychondritis (RP) is a rare autoimmune systemic disease, especially in childhood. To ... more Relapsing polychondritis (RP) is a rare autoimmune systemic disease, especially in childhood. To report three new pediatric RP cases, to provide a literature review and to compare with adulthood disease, retrospective data collection from three childhood RP cases was observed in a Brazilian Pediatric Rheumatology Division. A literature review based on a MEDLINE database search was performed. Arthritis and auricular chondritis were present in our three patients. Two cases presented with early and severe laryngotracheal chondritis, besides initial and symptomatic costochondritis. The other case developed prominent epiphyseal plate involvement. Two patients were refractory to corticosteroids and immunosuppressants and required the use of TNF-alpha inhibitors to improve the symptoms, while corticosteroids plus methotrexate induced remission in the other patient. The literature review showed 44 cases of pediatric-onset disease in English language. Arthritis and ear chondritis are the most common initial and cumulative manifestations of RP in children and adults. Nasal and laryngotracheobronchial chondritis are also common manifestations observed during follow-up in childhood. There is also an early severity of respiratory chondritis in childhood, requiring aggressive treatment with corticosteroids, immunosuppressants and biologic agents. The data presented by those 3 children, considered in conjunction with the data from the 44 published cases, may reXect some distinguishing childhood RP features, such as more severe and frequent respiratory tract involvement, symptomatic costochondritis and the atypical pattern of persistent and destructive arthritis with epiphyseal plate involvement. Response to immunosuppressants and biologic agents is anecdotal, but steroids remain the main drug during the Xares.

... Imaging Findings in ECT-Induced Delirium Gary S. Figiel, MD C. Edward Coffey, MD William T. D... more ... Imaging Findings in ECT-Induced Delirium Gary S. Figiel, MD C. Edward Coffey, MD William T. Djang, MD Graham Hoffman, Jr., MD P. Murali Doraiswamy, MD ... The brain MRI scans were analyzed independently by ... Summers et al.11 have reported that preexisting, chronic ...

Handbook of Neuro-Oncology NeuroImaging, 2008

PURPOSE/AIM The placenta serves as the organ providing oxygen and nutrition to the fetus. In case... more PURPOSE/AIM The placenta serves as the organ providing oxygen and nutrition to the fetus. In cases of placenta pathologies, disturbances in the exchange may lead to intrauterine growth restriction, prematurity and intrauterine fetal death. Although ultrasound and Doppler flow sonography are the gold standard methods to evaluation of the placenta, MRI has become an important tool in the assessment of unclear diagnosis with ultrasound. CONTENT ORGANIZATION - Anatomy of the placenta (basal plate, placenta lobule, cotyledon) - Placenta maturation (Grannum-Classification in ultrasound and adaptation to MRI) - Calcification of the placenta - Placental shape - Placental shape abnormalities- circunvalata, bilobata. - Pathologies of the placenta: septal cysts, infarction, trombi, placental lakes, retroplacental hematoma, chorangioma, molar pregnancy, placenta previa, abnormal plancetal invasion - Umbilical cord: single umbilical artery, hypercoiling umbilical cord, umbilical cord knots, umbi...

Radiologia Brasileira

OBJETIVO: Estudar a utilidade da sequência pesada em difusão na diferenciação das lesões mamárias... more OBJETIVO: Estudar a utilidade da sequência pesada em difusão na diferenciação das lesões mamárias benignas e malignas. MATERIAIS E MÉTODOS: Quarenta e cinco mulheres (idade média de 46,1 anos) com 52 nódulos de mama foram submetidas a ressonância magnética acrescida da sequência difusão. O coeficiente de difusão aparente (ADC) foi calculado através do mapa de ADC obtido pelo uso de cinco valores de b (0, 250, 500, 750 e 1.000 s/mm2). O valor de ADC médio de cada lesão foi correlacionado com achados de imagem e resultados histopatológicos. Valores de ADC de corte, sensibilidade e especificidade da sequência difusão na diferenciação das lesões benignas e malignas foram calculados. P < 0,05 foi considerado estatisticamente significativo. RESULTADOS: O valor de ADC médio foi significativamente menor para as lesões malignas (0,92 ± 0,26 × 10–3 mm2/s) comparado com as lesões benignas (1,50 ± 0,34 × 10–3 mm2/s) (p < 0,0001). A sequência difusão mostrou altas sensibilidade e especific...

PURPOSE Advances in imaging technology have led to vast improvements in placenta evaluation. Magn... more PURPOSE Advances in imaging technology have led to vast improvements in placenta evaluation. Magnetic resonance (MR) imaging may be used in specific cases, providing additional information about abnormalities and situations where the ultrasound information was limited. Twin to twin transfusion syndrome (TTTS) is a disease of the placenta that affects monochorionic twin pregnancies. Laser ablation of the chorionic plate anastomotic vessels along the vascular equator can be a resolutive procedure. To have a successful fetoscopy, the placental identification of the vascular equator and the choice of the region suitable for fetoscope entry are very important. Virtual fetoscopy (VF) can be an alternative to identify the placental equator region when ultrasound faces difficulties. The objective of this study is to describe the virtual 3D view of the placenta performed in twin pregnancy complicated by TTTS. METHOD AND MATERIALS The MR imaging was performed in the third trimester of gestati...

Radiologia Brasileira, 2010

The combination of positron emission tomography (PET) with magnetic resonance imaging (MRI) has b... more The combination of positron emission tomography (PET) with magnetic resonance imaging (MRI) has been the subject of several studies in recent years. Positron emission tomography is the most sensitive and specific imaging modality in the detection of metabolic changes, ...

Radiologia Brasileira, 2009

... Maene Marcondes Cardoso1, Heron Werner Junior2, Plínio Tostes Berardo3, Antônio Carlos Coutin... more ... Maene Marcondes Cardoso1, Heron Werner Junior2, Plínio Tostes Berardo3, Antônio Carlos Coutinho Junior4, Marisa Nassar Aidar Domingues4 ... estruturas em compartimentos anterior (es-paço vesicouterino, bexiga e ureter) e pos-terior (colo uterino, ligamento uterossacro ...

Neuroimaging Clinics of North America, 2011

Diffusion-weighted magnetic resonance imaging (DWI) provides image contrasts that are different f... more Diffusion-weighted magnetic resonance imaging (DWI) provides image contrasts that are different from conventional magnetic resonance techniques. DWI is particularly sensitive for detecting acute ischemic stroke, but it also has many other clinical applications, including the evaluation of central nervous system (CNS) infections. This article addresses the role of DWI in the differential diagnosis of CNS infections, and discusses the most common DWI findings for each type of infection.

Radiologia Brasileira, 2004

Radiologia Brasileira, 2008

OBJETIVO: Correlacionar os achados ultra-sonográficos e de ressonância magnética no teratoma sacr... more OBJETIVO: Correlacionar os achados ultra-sonográficos e de ressonância magnética no teratoma sacrococcígeo fetal. MATERIAIS E MÉTODOS: Três pacientes com idade gestacional entre 30 e 35 semanas, com diagnóstico ultra-sonográfico suspeito de teratoma sacrococcígeo fetal, foram submetidas a ressonância magnética e, posteriormente, a ultra-sonografia para correlação dos achados. Tanto na ressonância magnética quanto na ultra-sonografia foram avaliadas as dimensões, a localização, a extensão e os conteúdos dos tumores. RESULTADOS: A ultra-sonografia e a ressonância magnética obtiveram resultados semelhantes em relação à localização, ao tamanho e ao conteúdo dos tumores. Todas as lesões localizavam-se na região sacrococcígea, com dimensões médias de 6,0 cm x 9,0 cm. Quanto ao conteúdo dos tumores, um dos casos era completamente cístico e dois eram sólidos e císticos. A extensão exata das lesões foi mais bem avaliada pela ressonância magnética do que pela ultra-sonografia, mostrando de forma adequada o acometimento pélvico nos três casos. CONCLUSÃO: A ressonância magnética fetal é capaz de complementar os achados ultra-sonográficos do teratoma sacrococcígeo fetal, uma vez que determina com melhor precisão o conteúdo e a extensão do tumor, auxiliando na conduta terapêutica e aumentando as chances de cura desses fetos. Unitermos: Feto; Teratoma sacrococcígeo; Ultra-sonografia; Imagem por ressonância magnética.

Radiologia Brasileira, 2009

... experimental, Documentos relacionados. Id: 530177, LILACS-Express. Autor: Antunes, Erika da G... more ... experimental, Documentos relacionados. Id: 530177, LILACS-Express. Autor: Antunes, Erika da Gloria; Werner Junior, Heron; Daltro, Pedro Augusto; Rodrigues, Leise; Amim, Bruno; Guerra, Fernando; Domingues, Romeu Côrtes; Gasparetto, Emerson Leandro. ...

Pituitary, 2013

ABSTRACT Obesity is the main risk factor for the development of obstructive sleep apnea (OSA). Hy... more ABSTRACT Obesity is the main risk factor for the development of obstructive sleep apnea (OSA). Hyperprolactinemia has also been related to obesity. To determine the OSA prevalence in patients with prolactinoma before and after dopamine agonist (DA) and to evaluate the correlation between the apnea-hypopnea index (AHI) and prolactin levels, body mass index (BMI), waist circumference (WC), visceral fat volume (VFV), subcutaneous fat volume, and other metabolic parameters. Thirty-five patients with prolactinoma at baseline and twenty-one who completed the 6-month DA treatment were submitted to clinical/laboratorial evaluations, polysomnography and abdominal imaging. Before treatment, the prevalence of obesity/overweight and OSA were, respectively, 68.5 and 34.2 %. We found a positive correlation between AHI and weight (r = 0.57; p &lt; 0.001), BMI (r = 0.56; p &lt; 0.001), WC (r = 0.61; p &lt; 0.001), VFV (r = 0.55; p = 0.002), insulin levels (r = 0.57; p &lt; 0.001), and HOMA-IR index (r = 0.57; p &lt; 0.001); and a negative correlation between AHI and HDL-cholesterol (r = -0.47; p = 0.005). After multivariate analysis, VFV and insulin levels were the most important predictors for AHI (p = 0.001 and p = 0.02, respectively). After DA, the obesity/overweight and OSA prevalence did not change. The OSA prevalence in patients with prolactinoma is similar to the obese subjects and did not change after treatment. Higher BMI and visceral obesity, but not prolactin levels, seem to be the major factor involved in the occurrence of OSA in these patients.

Radiologia Brasileira, 2009

... Fernanda Philadelpho Arantes Pereira1, Gabriela Martins2, Eduardo Figueiredo3, Marisa Nassar ... more ... Fernanda Philadelpho Arantes Pereira1, Gabriela Martins2, Eduardo Figueiredo3, Marisa Nassar Aidar Domingues2, Romeu Côrtes Domingues4, Lea Mirian Barbosa da ... Quarenta e cinco mulheres (idade média de 46,1 anos) com 52 nódulos de mama foram submetidas a ...

Neuroimaging Clinics of North America, 2011

For over 20 years, conventional MR imaging has been used for assessing brain tumors. However, con... more For over 20 years, conventional MR imaging has been used for assessing brain tumors. However, conventional MR imaging tends to underestimate the extent of the tumor, perhaps leading to suboptimal treatment. New MR imaging tools have been widely used to determine the grade, heterogeneity, and extent of brain tumors. Diffusion-weighted imaging has been studied extensively, helping in tumor grading, differential diagnosis, and postoperative evaluation. Diffusion tensor imaging can apparently delineate more accurately the tumor versus the infiltrating tumor between the peritumoral edema and the normal brain parenchyma. This article shows the main clinical applications of these sequences.

Magnetic Resonance Imaging Clinics of North America, 2011

Diffusion-weighted imaging has been used extensively in clinical practice for the early diagnosis... more Diffusion-weighted imaging has been used extensively in clinical practice for the early diagnosis of central nervous system conditions that restrict the diffusion of water molecules because it provides information about tumor cellularity or abscesses containing viscous fluid. DTI can detect brain lesions before any conventional imaging. Even though the role of these modalities is well defined for many neurologic lesions that affect the brain, its clinical application in spinal cord diseases is increasing. This article discusses the several central nervous system conditions that may be diagnosed with diffusion imaging.

Radiologia Brasileira, 2008

O valor da US e da RM fetal na avaliação das hérnias diafragmáticas ... O valor da ultra-sonograf... more O valor da US e da RM fetal na avaliação das hérnias diafragmáticas ... O valor da ultra-sonografia e da ressonância magnética ... The value of fetal ultrasonography and magnetic resonance imaging in the assessment of diaphragmatic hernias ... Bruno Amim1, Heron Werner Jr.2, ...

Radiologia Brasileira, 2010

Radiologia Brasileira, 2001

Neste trabalho foram avaliados 43 exames de ressonância magnética de perna ou coxa, com alteraçõe... more Neste trabalho foram avaliados 43 exames de ressonância magnética de perna ou coxa, com alterações traumáticas relacionadas à prática de esportes. Os estiramentos foram as lesões mais encontradas e apresentaram imagem iso ou hipointensa em T1 e hiperintensa em T2, sendo classificados, de acordo com a porcentagem de fibras lesadas, em graus 1, 2 e 3. Em segundo foram observadas as contusões, cujas características foram sinal hipo ou isointenso em T1 e hiperintenso em T2, e, por fim, as fibroses, que se caracterizaram por sinal hipointenso em T1 e em T2. Unitermos: Injúrias musculares. Atletas. Ressonância magnética.

ABSTRACT PURPOSE/AIM Congenital urinary lesions are typically best assessed with ultrasound (US).... more ABSTRACT PURPOSE/AIM Congenital urinary lesions are typically best assessed with ultrasound (US). MR imaging is an important adjunct method in the assessment of the fetal urinary pathologies. The purpose of this exhibit is to illustrate the most common MR findings in fetuses with urinary pathologies and to correlate these features with the prenatal US abnormalities. CONTENT ORGANIZATION - MR imaging protocol and normal anatomy patterns - Urinary lesions • Hydronephrosis and Pelvicaliectasis: ureteropelvic junction obstruction; posterior urethral valves; duplex kidneys • Renal agenesis • Ectopic Kidneys • Horseshoe kidney • Renal cystic diseases: multicystic dysplastic kidney, autosomal recessive polycystic kidney, isolated renal cyst • Prune-belly syndrome • Cloacal malformation SUMMARY • The MRI is a useful imaging technique for the evaluation of fetal urinary tract • The use of an adequate MRI protocol and the knowledge of the normal anatomy patters are key points when evaluating fetuses with urinary pathologies • In most of the urinary pathologies, the fetal MR imaging provides important findings that help defining the differential diagnosis • There is a good correlation between prenatal MR imaging and US in fetuses with urinary abnormalities

Rheumatology International, Jul 1, 2013

Relapsing polychondritis (RP) is a rare autoimmune systemic disease, especially in childhood. To ... more Relapsing polychondritis (RP) is a rare autoimmune systemic disease, especially in childhood. To report three new pediatric RP cases, to provide a literature review and to compare with adulthood disease, retrospective data collection from three childhood RP cases was observed in a Brazilian Pediatric Rheumatology Division. A literature review based on a MEDLINE database search was performed. Arthritis and auricular chondritis were present in our three patients. Two cases presented with early and severe laryngotracheal chondritis, besides initial and symptomatic costochondritis. The other case developed prominent epiphyseal plate involvement. Two patients were refractory to corticosteroids and immunosuppressants and required the use of TNF-alpha inhibitors to improve the symptoms, while corticosteroids plus methotrexate induced remission in the other patient. The literature review showed 44 cases of pediatric-onset disease in English language. Arthritis and ear chondritis are the most common initial and cumulative manifestations of RP in children and adults. Nasal and laryngotracheobronchial chondritis are also common manifestations observed during follow-up in childhood. There is also an early severity of respiratory chondritis in childhood, requiring aggressive treatment with corticosteroids, immunosuppressants and biologic agents. The data presented by those 3 children, considered in conjunction with the data from the 44 published cases, may reXect some distinguishing childhood RP features, such as more severe and frequent respiratory tract involvement, symptomatic costochondritis and the atypical pattern of persistent and destructive arthritis with epiphyseal plate involvement. Response to immunosuppressants and biologic agents is anecdotal, but steroids remain the main drug during the Xares.

... Imaging Findings in ECT-Induced Delirium Gary S. Figiel, MD C. Edward Coffey, MD William T. D... more ... Imaging Findings in ECT-Induced Delirium Gary S. Figiel, MD C. Edward Coffey, MD William T. Djang, MD Graham Hoffman, Jr., MD P. Murali Doraiswamy, MD ... The brain MRI scans were analyzed independently by ... Summers et al.11 have reported that preexisting, chronic ...

Handbook of Neuro-Oncology NeuroImaging, 2008

PURPOSE/AIM The placenta serves as the organ providing oxygen and nutrition to the fetus. In case... more PURPOSE/AIM The placenta serves as the organ providing oxygen and nutrition to the fetus. In cases of placenta pathologies, disturbances in the exchange may lead to intrauterine growth restriction, prematurity and intrauterine fetal death. Although ultrasound and Doppler flow sonography are the gold standard methods to evaluation of the placenta, MRI has become an important tool in the assessment of unclear diagnosis with ultrasound. CONTENT ORGANIZATION - Anatomy of the placenta (basal plate, placenta lobule, cotyledon) - Placenta maturation (Grannum-Classification in ultrasound and adaptation to MRI) - Calcification of the placenta - Placental shape - Placental shape abnormalities- circunvalata, bilobata. - Pathologies of the placenta: septal cysts, infarction, trombi, placental lakes, retroplacental hematoma, chorangioma, molar pregnancy, placenta previa, abnormal plancetal invasion - Umbilical cord: single umbilical artery, hypercoiling umbilical cord, umbilical cord knots, umbi...

Radiologia Brasileira

OBJETIVO: Estudar a utilidade da sequência pesada em difusão na diferenciação das lesões mamárias... more OBJETIVO: Estudar a utilidade da sequência pesada em difusão na diferenciação das lesões mamárias benignas e malignas. MATERIAIS E MÉTODOS: Quarenta e cinco mulheres (idade média de 46,1 anos) com 52 nódulos de mama foram submetidas a ressonância magnética acrescida da sequência difusão. O coeficiente de difusão aparente (ADC) foi calculado através do mapa de ADC obtido pelo uso de cinco valores de b (0, 250, 500, 750 e 1.000 s/mm2). O valor de ADC médio de cada lesão foi correlacionado com achados de imagem e resultados histopatológicos. Valores de ADC de corte, sensibilidade e especificidade da sequência difusão na diferenciação das lesões benignas e malignas foram calculados. P < 0,05 foi considerado estatisticamente significativo. RESULTADOS: O valor de ADC médio foi significativamente menor para as lesões malignas (0,92 ± 0,26 × 10–3 mm2/s) comparado com as lesões benignas (1,50 ± 0,34 × 10–3 mm2/s) (p < 0,0001). A sequência difusão mostrou altas sensibilidade e especific...

PURPOSE Advances in imaging technology have led to vast improvements in placenta evaluation. Magn... more PURPOSE Advances in imaging technology have led to vast improvements in placenta evaluation. Magnetic resonance (MR) imaging may be used in specific cases, providing additional information about abnormalities and situations where the ultrasound information was limited. Twin to twin transfusion syndrome (TTTS) is a disease of the placenta that affects monochorionic twin pregnancies. Laser ablation of the chorionic plate anastomotic vessels along the vascular equator can be a resolutive procedure. To have a successful fetoscopy, the placental identification of the vascular equator and the choice of the region suitable for fetoscope entry are very important. Virtual fetoscopy (VF) can be an alternative to identify the placental equator region when ultrasound faces difficulties. The objective of this study is to describe the virtual 3D view of the placenta performed in twin pregnancy complicated by TTTS. METHOD AND MATERIALS The MR imaging was performed in the third trimester of gestati...

Radiologia Brasileira, 2010

The combination of positron emission tomography (PET) with magnetic resonance imaging (MRI) has b... more The combination of positron emission tomography (PET) with magnetic resonance imaging (MRI) has been the subject of several studies in recent years. Positron emission tomography is the most sensitive and specific imaging modality in the detection of metabolic changes, ...

Radiologia Brasileira, 2009

... Maene Marcondes Cardoso1, Heron Werner Junior2, Plínio Tostes Berardo3, Antônio Carlos Coutin... more ... Maene Marcondes Cardoso1, Heron Werner Junior2, Plínio Tostes Berardo3, Antônio Carlos Coutinho Junior4, Marisa Nassar Aidar Domingues4 ... estruturas em compartimentos anterior (es-paço vesicouterino, bexiga e ureter) e pos-terior (colo uterino, ligamento uterossacro ...

Neuroimaging Clinics of North America, 2011

Diffusion-weighted magnetic resonance imaging (DWI) provides image contrasts that are different f... more Diffusion-weighted magnetic resonance imaging (DWI) provides image contrasts that are different from conventional magnetic resonance techniques. DWI is particularly sensitive for detecting acute ischemic stroke, but it also has many other clinical applications, including the evaluation of central nervous system (CNS) infections. This article addresses the role of DWI in the differential diagnosis of CNS infections, and discusses the most common DWI findings for each type of infection.

Radiologia Brasileira, 2004

Radiologia Brasileira, 2008

OBJETIVO: Correlacionar os achados ultra-sonográficos e de ressonância magnética no teratoma sacr... more OBJETIVO: Correlacionar os achados ultra-sonográficos e de ressonância magnética no teratoma sacrococcígeo fetal. MATERIAIS E MÉTODOS: Três pacientes com idade gestacional entre 30 e 35 semanas, com diagnóstico ultra-sonográfico suspeito de teratoma sacrococcígeo fetal, foram submetidas a ressonância magnética e, posteriormente, a ultra-sonografia para correlação dos achados. Tanto na ressonância magnética quanto na ultra-sonografia foram avaliadas as dimensões, a localização, a extensão e os conteúdos dos tumores. RESULTADOS: A ultra-sonografia e a ressonância magnética obtiveram resultados semelhantes em relação à localização, ao tamanho e ao conteúdo dos tumores. Todas as lesões localizavam-se na região sacrococcígea, com dimensões médias de 6,0 cm x 9,0 cm. Quanto ao conteúdo dos tumores, um dos casos era completamente cístico e dois eram sólidos e císticos. A extensão exata das lesões foi mais bem avaliada pela ressonância magnética do que pela ultra-sonografia, mostrando de forma adequada o acometimento pélvico nos três casos. CONCLUSÃO: A ressonância magnética fetal é capaz de complementar os achados ultra-sonográficos do teratoma sacrococcígeo fetal, uma vez que determina com melhor precisão o conteúdo e a extensão do tumor, auxiliando na conduta terapêutica e aumentando as chances de cura desses fetos. Unitermos: Feto; Teratoma sacrococcígeo; Ultra-sonografia; Imagem por ressonância magnética.

Radiologia Brasileira, 2009

... experimental, Documentos relacionados. Id: 530177, LILACS-Express. Autor: Antunes, Erika da G... more ... experimental, Documentos relacionados. Id: 530177, LILACS-Express. Autor: Antunes, Erika da Gloria; Werner Junior, Heron; Daltro, Pedro Augusto; Rodrigues, Leise; Amim, Bruno; Guerra, Fernando; Domingues, Romeu Côrtes; Gasparetto, Emerson Leandro. ...

Pituitary, 2013

ABSTRACT Obesity is the main risk factor for the development of obstructive sleep apnea (OSA). Hy... more ABSTRACT Obesity is the main risk factor for the development of obstructive sleep apnea (OSA). Hyperprolactinemia has also been related to obesity. To determine the OSA prevalence in patients with prolactinoma before and after dopamine agonist (DA) and to evaluate the correlation between the apnea-hypopnea index (AHI) and prolactin levels, body mass index (BMI), waist circumference (WC), visceral fat volume (VFV), subcutaneous fat volume, and other metabolic parameters. Thirty-five patients with prolactinoma at baseline and twenty-one who completed the 6-month DA treatment were submitted to clinical/laboratorial evaluations, polysomnography and abdominal imaging. Before treatment, the prevalence of obesity/overweight and OSA were, respectively, 68.5 and 34.2 %. We found a positive correlation between AHI and weight (r = 0.57; p &lt; 0.001), BMI (r = 0.56; p &lt; 0.001), WC (r = 0.61; p &lt; 0.001), VFV (r = 0.55; p = 0.002), insulin levels (r = 0.57; p &lt; 0.001), and HOMA-IR index (r = 0.57; p &lt; 0.001); and a negative correlation between AHI and HDL-cholesterol (r = -0.47; p = 0.005). After multivariate analysis, VFV and insulin levels were the most important predictors for AHI (p = 0.001 and p = 0.02, respectively). After DA, the obesity/overweight and OSA prevalence did not change. The OSA prevalence in patients with prolactinoma is similar to the obese subjects and did not change after treatment. Higher BMI and visceral obesity, but not prolactin levels, seem to be the major factor involved in the occurrence of OSA in these patients.

Radiologia Brasileira, 2009

... Fernanda Philadelpho Arantes Pereira1, Gabriela Martins2, Eduardo Figueiredo3, Marisa Nassar ... more ... Fernanda Philadelpho Arantes Pereira1, Gabriela Martins2, Eduardo Figueiredo3, Marisa Nassar Aidar Domingues2, Romeu Côrtes Domingues4, Lea Mirian Barbosa da ... Quarenta e cinco mulheres (idade média de 46,1 anos) com 52 nódulos de mama foram submetidas a ...

Neuroimaging Clinics of North America, 2011

For over 20 years, conventional MR imaging has been used for assessing brain tumors. However, con... more For over 20 years, conventional MR imaging has been used for assessing brain tumors. However, conventional MR imaging tends to underestimate the extent of the tumor, perhaps leading to suboptimal treatment. New MR imaging tools have been widely used to determine the grade, heterogeneity, and extent of brain tumors. Diffusion-weighted imaging has been studied extensively, helping in tumor grading, differential diagnosis, and postoperative evaluation. Diffusion tensor imaging can apparently delineate more accurately the tumor versus the infiltrating tumor between the peritumoral edema and the normal brain parenchyma. This article shows the main clinical applications of these sequences.

Magnetic Resonance Imaging Clinics of North America, 2011

Diffusion-weighted imaging has been used extensively in clinical practice for the early diagnosis... more Diffusion-weighted imaging has been used extensively in clinical practice for the early diagnosis of central nervous system conditions that restrict the diffusion of water molecules because it provides information about tumor cellularity or abscesses containing viscous fluid. DTI can detect brain lesions before any conventional imaging. Even though the role of these modalities is well defined for many neurologic lesions that affect the brain, its clinical application in spinal cord diseases is increasing. This article discusses the several central nervous system conditions that may be diagnosed with diffusion imaging.

Radiologia Brasileira, 2008

O valor da US e da RM fetal na avaliação das hérnias diafragmáticas ... O valor da ultra-sonograf... more O valor da US e da RM fetal na avaliação das hérnias diafragmáticas ... O valor da ultra-sonografia e da ressonância magnética ... The value of fetal ultrasonography and magnetic resonance imaging in the assessment of diaphragmatic hernias ... Bruno Amim1, Heron Werner Jr.2, ...

Radiologia Brasileira, 2010

Radiologia Brasileira, 2001

Neste trabalho foram avaliados 43 exames de ressonância magnética de perna ou coxa, com alteraçõe... more Neste trabalho foram avaliados 43 exames de ressonância magnética de perna ou coxa, com alterações traumáticas relacionadas à prática de esportes. Os estiramentos foram as lesões mais encontradas e apresentaram imagem iso ou hipointensa em T1 e hiperintensa em T2, sendo classificados, de acordo com a porcentagem de fibras lesadas, em graus 1, 2 e 3. Em segundo foram observadas as contusões, cujas características foram sinal hipo ou isointenso em T1 e hiperintenso em T2, e, por fim, as fibroses, que se caracterizaram por sinal hipointenso em T1 e em T2. Unitermos: Injúrias musculares. Atletas. Ressonância magnética.