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Papers by Rosa Rivera

Anuario De Psicologia Clinica Y De La Salud Annuary of Clinical and Health Psychology, 2012

Psicologia Conductual Behavioral Psychology Revista Internacional De Psicologia Clinica Y De La Salud, 2010

Tecnicas De Modificacion De Conducta 2011 Isbn 978 84 368 2229 8 Pags 659 672, 2011

Salud Mental, Feb 1, 2012

Ariadna Cultura Educacion Y Tecnologia, Jul 1, 2013

Psicooncologia Investigacion Y Clinica Biopsicosocial En Oncologia, 2013

Cuadernos De Medicina Psicosomatica Y Psiquiatria De Enlace, 2007

Revista De Psicopatologia Y Psicologia Clinica, Sep 1, 2005

^Universidad de Valencia ^Universidad Jaime I de Castellón (Aceptado en febrero de 2005) Este tra... more ^Universidad de Valencia ^Universidad Jaime I de Castellón (Aceptado en febrero de 2005) Este trabajo tiene como objetivo validar en población española la Escala de Estima Corporal (BodyEsteem Scale -BES), elaborada por Franzoi y Shields (1984). La escala fue aplicada a una muestra total de 288 participantes (212 mujeres y 72 varones), con un rango de edad entre 14 y 29 años, procedentes de escuelas, institutos y facultades universitarias. En este estudio se ofrecen datos sobre la consistencia interna, estabilidad temporal (1 mes), validez convergente y análisis factorial. Además, se encuentran diferencias en la estima corporal entre varones y mujeres, en función de la edad, del índice de Masa Corporal (IMC), y de las puntuaciones en el EAT-40 y la Escala de Restricción.

Manual Para La Evaluacion Clinica De Los Trastornos Psicologicos Estrategias De Evaluacion Problemas Infantiles Y Trastornos De Ansiedad 2005 Isbn 84 368 1998 5 Pags 403 425, 2005

Acta Neuropathologica, Mar 1, 2000

Caspases play crucial roles in the inflammatory response and in the cell pathway leading to apopt... more Caspases play crucial roles in the inflammatory response and in the cell pathway leading to apoptosis. Caspase 1 (ICE), 2 (Nedd2), 3 (CPP32), 6 (Mch2) and 8 (Mch5, FLICE) expression was examined using immunohistochemistry in the brains of rats and gerbils following systemic administration of kainic acid (KA). The distribution of caspase expression was compared with the distribution of c-Fos expression, a transcription factor that is produced in response to the excitotoxic insult. Strong caspase 2 immunoreactivity was found in microglia up to 6 h following KA administration. Focal strong expression of caspases 1, 2, 3, 6 and 8 was observed in astrocytes and neurons, from 12 to 48 h after KA injection, in areas in which a number of neurons were committed to die. This distribution was in contrast with the generalised distribution of c-Fos expression following KA administration. Only a minority of neurons in the entorhinal cortex, amygdala and hilus, but a majority of neurons in selected thalamic nuclei, exhibited strong caspase expression in KA-treated rats. Similar findings, although minimised, were observed in KA-treated gerbils. Double-labelling caspase immunohistochemistry and in situ end-labelling of nuclear DNA fragmentation disclosed co-localisation of strong caspase expression and nuclear DNA breaks in a small percentage of neurons but no co-localisation in astrocytes. Western blots of entorhinal cortex and neocortex homogenates showed cleavage of certain caspase substrates in KA-treated rats. The intensity of the bands corresponding to lamin B and protein kinase C-delta was decreased in the entorhinal cortex following KA administration. Several bands appeared in the entorhinal cortex and neocortex paragraph signin Western blots processed for the demonstration of poly(ADP-ribose) polymerase (PARP), thus indicating that other proteases, in addition to caspases, cleaved PARP following KA administration. Taken together, these findings indicate that KA excitotoxicity triggers caspase expression which, although predominant in regions subjected to irreversible cell damage, has only a weak association with the presence of nuclear DNA breaks and neuron cell death. Although these results suggest caspase activation, further studies have to be performed to elucidate whether caspase activation plays a crucial role in KA excitotoxicity.

Cuadernos De Medicina Psicosomatica Y Psiquiatria De Enlace, 2007

... En: Análisis y Modificación de Conducta Valencia 1998, v. 24, n. 93; p. 5-26. ... Se trata de... more ... En: Análisis y Modificación de Conducta Valencia 1998, v. 24, n. 93; p. 5-26. ... Se trata de una nueva tecnología consistente en un entorno gráfico en el que el usuario, no sólo tiene la sensación de encontrarse físicamente presente en el mundo virtual, sino que además puede ...

Journal of the Neurological Sciences, May 31, 1994

Serial sections of cortical resection of 30 patients suffering from drug-resistant epilepsy were ... more Serial sections of cortical resection of 30 patients suffering from drug-resistant epilepsy were processed for parvalbumin and calbindin-D28k immunocytochemistry to determine local circuit neuron populations. Our findings indicate that there is not a simple mechanism to explain neocortical epileptic loci. On the basis of the present results it can be suggested that: (1) reduced percentage of local circuit neurons in the vicinity of neoplasms may account for a decreased intracortical inhibition. (2) Abnormal morphology and distribution of local circuit neurons may result in abnormal cortical inhibition in patients with focal cortical dysplasia, and, probably, in other focal migrational disorders, including neuronal nests in the white matter. (3) Increased percentages of immunoreactive local circuit neurons and fibers in focal neocortical necrosis (cavernous angiomas), diffuse hypoxic encephalopathy, and hippocampus in patients with temporal lobe epilepsy due to mesial sclerosis, may play a role in epilepsy. These neurons can be activated by reduced excitatory inputs, or they may establish abnormal synaptic contacts with other inhibitory neurons. (4) Lack of consistent morphotogic abnormalities in the neocortex of patients with temporal lobe epilepsy, and in patients with cryptogenetic frontal lobe epilepsy, suggests that electrically abnormal neocortical foci in these cases are probably epiphenomena.

Revista De Psicopatologia Y Psicologia Clinica, 2014

ABSTRACT Resumen: Las aplicaciones de tecnologías avanzadas han generado la emergencia de un espa... more ABSTRACT Resumen: Las aplicaciones de tecnologías avanzadas han generado la emergencia de un espacio de investigación en ciencias del comportamiento. El creciente acervo de publicaciones, sobre la eficacia y eficiencia de programas de intervención para una serie de trastornos psicológicos, plan-tea la necesidad de fortalecerlos, evaluando su generalización a otros contextos culturales para contribuir a la medición de la validez externa. Mediante la colaboración de dos grupos de investi-gación, se realizó la validación transcultural de tres intervenciones empleando realidad virtual para el tratamiento de miedo a volar, agorafobia y miedo a hablar en público con un programa auto-apli-cado, que demostraron previamente eficacia con población española. Se informan los resultados de eficacia y eficiencia de las intervenciones en población mexicana. Se discute la relevancia de la validez externa de los programas de tratamiento con incorporación tecnológica, que pueden con-tribuir a optimizar tratamientos y sistemas de valoración psicológica beneficiando los servicios de salud mental. Palabras clave: Práctica basada en evidencia; tratamientos realidad virtual; programas auto-apli-cados; validez externa; trastornos de ansiedad.

Gestion Practica De Riesgos Laborales Integracion Y Desarrollo De La Gestion De La Prevencion, 2012

Acta Crystallographica Section D-biological Crystallography, 2001

Progress in Neurobiology, 1996

Transforming growth factor α (TGF-α) and epidermal growth factor-receptor (EGF-R) immunoreactivit... more Transforming growth factor α (TGF-α) and epidermal growth factor-receptor (EGF-R) immunoreactivity is observed in the majority of neurons, and in maturing astrocytes, in the developing and adult brain of humans and different species of animals. TGF-α and EGF-R co-localize in most neurons and maturing astrocytes, suggesting that most TGF-α producing cells are EGF-R-expressing cells. TGF-α and EGF-R immunoreactivity decrease in damaged areas following different insults. However, EGF-R appears in reactive glia, mostly reactive astrocytes, within and surrounding the damaged areas. TGF-α and EGF-R immunoreactivity is found in neurons of patients affected by Alzheimer's disease and other forms of dementia, and in neurons of patients suffering from epilepsy owing to different causes, thus pointing to the conclusion that TGF-α does not play a significant role in these pathologies. However, EGF-R immunoreactivity occurs in reactive astrocytes and microglia in subacute but not chronic lesions in human cases. Since TGF-α is a membrane-anchored growth factor, which may be cleaved leading to the formation of soluble forms, and both the membrane-anchored and soluble forms have the capacity to activate the EGF-R, it is feasible that TGF-α in the nervous system may act upon EGF-R-containing neurons through different mechanisms. In addition to distant effects resulting from the release of soluble TGF-α, local effects may be produced by establishing direct cell-to-cell contacts (juxtacrine stimulation), or in cells expressing both TGF-α and EGF-R (autocrine stimulation).

Anuario De Psicologia Clinica Y De La Salud Annuary of Clinical and Health Psychology, 2012

Psicologia Conductual Behavioral Psychology Revista Internacional De Psicologia Clinica Y De La Salud, 2010

Tecnicas De Modificacion De Conducta 2011 Isbn 978 84 368 2229 8 Pags 659 672, 2011

Salud Mental, Feb 1, 2012

Ariadna Cultura Educacion Y Tecnologia, Jul 1, 2013

Psicooncologia Investigacion Y Clinica Biopsicosocial En Oncologia, 2013

Cuadernos De Medicina Psicosomatica Y Psiquiatria De Enlace, 2007

Revista De Psicopatologia Y Psicologia Clinica, Sep 1, 2005

^Universidad de Valencia ^Universidad Jaime I de Castellón (Aceptado en febrero de 2005) Este tra... more ^Universidad de Valencia ^Universidad Jaime I de Castellón (Aceptado en febrero de 2005) Este trabajo tiene como objetivo validar en población española la Escala de Estima Corporal (BodyEsteem Scale -BES), elaborada por Franzoi y Shields (1984). La escala fue aplicada a una muestra total de 288 participantes (212 mujeres y 72 varones), con un rango de edad entre 14 y 29 años, procedentes de escuelas, institutos y facultades universitarias. En este estudio se ofrecen datos sobre la consistencia interna, estabilidad temporal (1 mes), validez convergente y análisis factorial. Además, se encuentran diferencias en la estima corporal entre varones y mujeres, en función de la edad, del índice de Masa Corporal (IMC), y de las puntuaciones en el EAT-40 y la Escala de Restricción.

Manual Para La Evaluacion Clinica De Los Trastornos Psicologicos Estrategias De Evaluacion Problemas Infantiles Y Trastornos De Ansiedad 2005 Isbn 84 368 1998 5 Pags 403 425, 2005

Acta Neuropathologica, Mar 1, 2000

Caspases play crucial roles in the inflammatory response and in the cell pathway leading to apopt... more Caspases play crucial roles in the inflammatory response and in the cell pathway leading to apoptosis. Caspase 1 (ICE), 2 (Nedd2), 3 (CPP32), 6 (Mch2) and 8 (Mch5, FLICE) expression was examined using immunohistochemistry in the brains of rats and gerbils following systemic administration of kainic acid (KA). The distribution of caspase expression was compared with the distribution of c-Fos expression, a transcription factor that is produced in response to the excitotoxic insult. Strong caspase 2 immunoreactivity was found in microglia up to 6 h following KA administration. Focal strong expression of caspases 1, 2, 3, 6 and 8 was observed in astrocytes and neurons, from 12 to 48 h after KA injection, in areas in which a number of neurons were committed to die. This distribution was in contrast with the generalised distribution of c-Fos expression following KA administration. Only a minority of neurons in the entorhinal cortex, amygdala and hilus, but a majority of neurons in selected thalamic nuclei, exhibited strong caspase expression in KA-treated rats. Similar findings, although minimised, were observed in KA-treated gerbils. Double-labelling caspase immunohistochemistry and in situ end-labelling of nuclear DNA fragmentation disclosed co-localisation of strong caspase expression and nuclear DNA breaks in a small percentage of neurons but no co-localisation in astrocytes. Western blots of entorhinal cortex and neocortex homogenates showed cleavage of certain caspase substrates in KA-treated rats. The intensity of the bands corresponding to lamin B and protein kinase C-delta was decreased in the entorhinal cortex following KA administration. Several bands appeared in the entorhinal cortex and neocortex paragraph signin Western blots processed for the demonstration of poly(ADP-ribose) polymerase (PARP), thus indicating that other proteases, in addition to caspases, cleaved PARP following KA administration. Taken together, these findings indicate that KA excitotoxicity triggers caspase expression which, although predominant in regions subjected to irreversible cell damage, has only a weak association with the presence of nuclear DNA breaks and neuron cell death. Although these results suggest caspase activation, further studies have to be performed to elucidate whether caspase activation plays a crucial role in KA excitotoxicity.

Cuadernos De Medicina Psicosomatica Y Psiquiatria De Enlace, 2007

... En: Análisis y Modificación de Conducta Valencia 1998, v. 24, n. 93; p. 5-26. ... Se trata de... more ... En: Análisis y Modificación de Conducta Valencia 1998, v. 24, n. 93; p. 5-26. ... Se trata de una nueva tecnología consistente en un entorno gráfico en el que el usuario, no sólo tiene la sensación de encontrarse físicamente presente en el mundo virtual, sino que además puede ...

Journal of the Neurological Sciences, May 31, 1994

Serial sections of cortical resection of 30 patients suffering from drug-resistant epilepsy were ... more Serial sections of cortical resection of 30 patients suffering from drug-resistant epilepsy were processed for parvalbumin and calbindin-D28k immunocytochemistry to determine local circuit neuron populations. Our findings indicate that there is not a simple mechanism to explain neocortical epileptic loci. On the basis of the present results it can be suggested that: (1) reduced percentage of local circuit neurons in the vicinity of neoplasms may account for a decreased intracortical inhibition. (2) Abnormal morphology and distribution of local circuit neurons may result in abnormal cortical inhibition in patients with focal cortical dysplasia, and, probably, in other focal migrational disorders, including neuronal nests in the white matter. (3) Increased percentages of immunoreactive local circuit neurons and fibers in focal neocortical necrosis (cavernous angiomas), diffuse hypoxic encephalopathy, and hippocampus in patients with temporal lobe epilepsy due to mesial sclerosis, may play a role in epilepsy. These neurons can be activated by reduced excitatory inputs, or they may establish abnormal synaptic contacts with other inhibitory neurons. (4) Lack of consistent morphotogic abnormalities in the neocortex of patients with temporal lobe epilepsy, and in patients with cryptogenetic frontal lobe epilepsy, suggests that electrically abnormal neocortical foci in these cases are probably epiphenomena.

Revista De Psicopatologia Y Psicologia Clinica, 2014

ABSTRACT Resumen: Las aplicaciones de tecnologías avanzadas han generado la emergencia de un espa... more ABSTRACT Resumen: Las aplicaciones de tecnologías avanzadas han generado la emergencia de un espacio de investigación en ciencias del comportamiento. El creciente acervo de publicaciones, sobre la eficacia y eficiencia de programas de intervención para una serie de trastornos psicológicos, plan-tea la necesidad de fortalecerlos, evaluando su generalización a otros contextos culturales para contribuir a la medición de la validez externa. Mediante la colaboración de dos grupos de investi-gación, se realizó la validación transcultural de tres intervenciones empleando realidad virtual para el tratamiento de miedo a volar, agorafobia y miedo a hablar en público con un programa auto-apli-cado, que demostraron previamente eficacia con población española. Se informan los resultados de eficacia y eficiencia de las intervenciones en población mexicana. Se discute la relevancia de la validez externa de los programas de tratamiento con incorporación tecnológica, que pueden con-tribuir a optimizar tratamientos y sistemas de valoración psicológica beneficiando los servicios de salud mental. Palabras clave: Práctica basada en evidencia; tratamientos realidad virtual; programas auto-apli-cados; validez externa; trastornos de ansiedad.

Gestion Practica De Riesgos Laborales Integracion Y Desarrollo De La Gestion De La Prevencion, 2012

Acta Crystallographica Section D-biological Crystallography, 2001

Progress in Neurobiology, 1996

Transforming growth factor α (TGF-α) and epidermal growth factor-receptor (EGF-R) immunoreactivit... more Transforming growth factor α (TGF-α) and epidermal growth factor-receptor (EGF-R) immunoreactivity is observed in the majority of neurons, and in maturing astrocytes, in the developing and adult brain of humans and different species of animals. TGF-α and EGF-R co-localize in most neurons and maturing astrocytes, suggesting that most TGF-α producing cells are EGF-R-expressing cells. TGF-α and EGF-R immunoreactivity decrease in damaged areas following different insults. However, EGF-R appears in reactive glia, mostly reactive astrocytes, within and surrounding the damaged areas. TGF-α and EGF-R immunoreactivity is found in neurons of patients affected by Alzheimer's disease and other forms of dementia, and in neurons of patients suffering from epilepsy owing to different causes, thus pointing to the conclusion that TGF-α does not play a significant role in these pathologies. However, EGF-R immunoreactivity occurs in reactive astrocytes and microglia in subacute but not chronic lesions in human cases. Since TGF-α is a membrane-anchored growth factor, which may be cleaved leading to the formation of soluble forms, and both the membrane-anchored and soluble forms have the capacity to activate the EGF-R, it is feasible that TGF-α in the nervous system may act upon EGF-R-containing neurons through different mechanisms. In addition to distant effects resulting from the release of soluble TGF-α, local effects may be produced by establishing direct cell-to-cell contacts (juxtacrine stimulation), or in cells expressing both TGF-α and EGF-R (autocrine stimulation).