Rosetta Lobreglio - Academia.edu (original) (raw)

Italian physician extertice in echocardiography

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Papers by Rosetta Lobreglio

Research paper thumbnail of Extensive cytoreductive surgery in advanced ovarian carcinoma

European Journal of Gynaecological Oncology, 1997

From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum ... more From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum cytoreductive surgery, and six to nine cycles of platinum-based chemotherapy. Six patients had stage IIIA-B disease, 101 stage IIIC, and 45 stage IV. Twenty-two tumors were grade 1. 58, grade 2. and 72, grade 3. Eighty-four patients (55%) presented with bulky tumors (> 10 cm in diameter). Optimal cytoreductive surgery (diameter of largest residual mass < 2 cm) was performed in 138 patients (91%). Fifty patients (33%) developed postoperative complications; 38 patients (25%) required a second laparotomy within a few days. Two postoperative deaths occurred. Overall 2-year and 4-year survival rates were 56% and 28%, respectively. There was a clear relationship between residual tumor and survival: the 2-year survival rate was 80% in the absence of residual tumor vs. 22% when the residuum exceeded 2 cm in diameter. The 2-year survival rate was 49% for tumor nodules < 2 cm in diameter....

Research paper thumbnail of A Systematic Review and International Web-Based Survey of randomized controlled trials in the perioperative and critical care setting: Interventions reducing mortality

Journal of Cardiothoracic and Vascular Anesthesia

Background We aimed to identify interventions documented by randomized controlled trials (RCTs) t... more Background We aimed to identify interventions documented by randomized controlled trials (RCTs) that reduce mortality in adult critically ill and perioperative patients, followed by a survey of clinicians' opinion and routine practice to understand the clinicians' response to such evidence. Methods

Research paper thumbnail of Extensive cytoreductive surgery in advanced ovarian carcinoma

European journal of gynaecological oncology, 1997

From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum ... more From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum cytoreductive surgery, and six to nine cycles of platinum-based chemotherapy. Six patients had stage IIIA-B disease, 101 stage IIIC, and 45 stage IV. Twenty-two tumors were grade 1. 58, grade 2. and 72, grade 3. Eighty-four patients (55%) presented with bulky tumors (> 10 cm in diameter). Optimal cytoreductive surgery (diameter of largest residual mass < 2 cm) was performed in 138 patients (91%). Fifty patients (33%) developed postoperative complications; 38 patients (25%) required a second laparotomy within a few days. Two postoperative deaths occurred. Overall 2-year and 4-year survival rates were 56% and 28%, respectively. There was a clear relationship between residual tumor and survival: the 2-year survival rate was 80% in the absence of residual tumor vs. 22% when the residuum exceeded 2 cm in diameter. The 2-year survival rate was 49% for tumor nodules < 2 cm in diameter....

Research paper thumbnail of Extensive cytoreductive surgery in advanced ovarian carcinoma

European Journal of Gynaecological Oncology, 1997

From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum ... more From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum cytoreductive surgery, and six to nine cycles of platinum-based chemotherapy. Six patients had stage IIIA-B disease, 101 stage IIIC, and 45 stage IV. Twenty-two tumors were grade 1. 58, grade 2. and 72, grade 3. Eighty-four patients (55%) presented with bulky tumors (> 10 cm in diameter). Optimal cytoreductive surgery (diameter of largest residual mass < 2 cm) was performed in 138 patients (91%). Fifty patients (33%) developed postoperative complications; 38 patients (25%) required a second laparotomy within a few days. Two postoperative deaths occurred. Overall 2-year and 4-year survival rates were 56% and 28%, respectively. There was a clear relationship between residual tumor and survival: the 2-year survival rate was 80% in the absence of residual tumor vs. 22% when the residuum exceeded 2 cm in diameter. The 2-year survival rate was 49% for tumor nodules < 2 cm in diameter....

Research paper thumbnail of A Systematic Review and International Web-Based Survey of randomized controlled trials in the perioperative and critical care setting: Interventions reducing mortality

Journal of Cardiothoracic and Vascular Anesthesia

Background We aimed to identify interventions documented by randomized controlled trials (RCTs) t... more Background We aimed to identify interventions documented by randomized controlled trials (RCTs) that reduce mortality in adult critically ill and perioperative patients, followed by a survey of clinicians' opinion and routine practice to understand the clinicians' response to such evidence. Methods

Research paper thumbnail of Extensive cytoreductive surgery in advanced ovarian carcinoma

European journal of gynaecological oncology, 1997

From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum ... more From June 1985 to June 1993, 152 patients with advanced ovarian cancer were treated with maximum cytoreductive surgery, and six to nine cycles of platinum-based chemotherapy. Six patients had stage IIIA-B disease, 101 stage IIIC, and 45 stage IV. Twenty-two tumors were grade 1. 58, grade 2. and 72, grade 3. Eighty-four patients (55%) presented with bulky tumors (> 10 cm in diameter). Optimal cytoreductive surgery (diameter of largest residual mass < 2 cm) was performed in 138 patients (91%). Fifty patients (33%) developed postoperative complications; 38 patients (25%) required a second laparotomy within a few days. Two postoperative deaths occurred. Overall 2-year and 4-year survival rates were 56% and 28%, respectively. There was a clear relationship between residual tumor and survival: the 2-year survival rate was 80% in the absence of residual tumor vs. 22% when the residuum exceeded 2 cm in diameter. The 2-year survival rate was 49% for tumor nodules < 2 cm in diameter....

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