Rudolf Klimek - Academia.edu (original) (raw)
Papers by Rudolf Klimek
Neuro endocrinology letters, 2012
Cancer appears in the new form of cell life as a direct consequence of self-organising pre-cancer... more Cancer appears in the new form of cell life as a direct consequence of self-organising pre-cancer cells (dissipathogenic systems), whose further existence is disabled by extreme impairment of their metabolism. Life itself is the highest value, since instead of necrosis or apoptosis, the cellular system in an unfavourable environment can change its genetic identity provided that the improvement in its own metabolism leads to increased chaos by higher dissipation of matter and energy in its environment. Prolongation of human life has resulted by a longer period of old age which is favourable for self-organisation of dissipative neoplastic cells. Modern medicine has explained the relation of the cervical cancer to preterm births and to inadequate use of oral contraceptives and/or replacement, instead of supplementary, neurohormonal therapy. Therefore, as early as in the period of pregnancy reproductive cells should be protected due to their prime importance in the intergenerational pas...
Current Gynecologic Oncology, 2010
Acta geneticae medicae et gemellologiae, 1972
The determination of oxytocinasemia is the method of choice in monitoring multiple pregnancy. An ... more The determination of oxytocinasemia is the method of choice in monitoring multiple pregnancy. An increase in the level of the enzyme indicates a normal development of the pregnancy.Although, as a rule, the oxytocinasemia level is higher in multiple than in single pregnancy, there are cases with a level pointing to intrauterine fetal danger, if, in a gestation beyond the seventh lunar month, it is lower than 4 μmol∣l∣min.The birth of a newborn with a body weight below 2500 g, when the oxytocinasemia level exceeds 12 I.U., indicates that a multiple pregnancy is involved.
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 20, 1964
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 4, 1963
Ginekologia polska, 2003
Apgar score remains permanent conquest of medicine due its objective evaluation of available poin... more Apgar score remains permanent conquest of medicine due its objective evaluation of available point counting of the level and quickness of newborn's breathing-circulation system adaptation to the new environment. For its example the score of fetal and newborn's maturation evaluation has been described. The matter is in this so that Apgar score don't be using for evaluation of fetal maturity because it is easy to determine it directly. Of course, the higher fetal maturity level the higher probability of high Apgar score, and the quicker and better post-partum child's adaptation for independent life in new circumstances takes place.
Early pregnancy (Online), 2001
Enzymes as biochemical markers come within the entire scope of the live mother-fetus system. The ... more Enzymes as biochemical markers come within the entire scope of the live mother-fetus system. The most important are the enzymes which regulate physiological processes, of which oxytocinase (a type of aminopeptidase) has a much wider scope of action than its name suggests, as it regulates also the level of aminopeptide hypothalamic hormones. Thus, it determines neurological, endocrinological and immunological regulation of entire steroidogenesis. Under the influence of gestational enlargement of the uterine cavity, the mothers hypothalamus produces an increasing amount of hormones, which in turn induces an increasing oxytocinase synthesis in the placenta in order to prevent the hormone in the blood reaching the level which could bring about uterine contractions. Also, the growing fetus additionally induces the production of oxytocinase by releasing its own hormones. All this occurs in combined action of the mother, fetus, placenta and even fetal membranes in one space-time process ca...
Ginekologia polska, 2000
The aim of the study is to define the systemic prognostic factors in the neoplasm according to th... more The aim of the study is to define the systemic prognostic factors in the neoplasm according to thermodynamic theory of cancer a the self-organising dissipative structure. As the local, so called "specific" factors seem to be not adequate one should look for more general ones. It is shown, that such general factors as hormonal state of women' organism, preterm births, lactation, infertility treatment are important.
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 20, 1967
La Revue française d'endocrinologie clinique, nutrition, et métabolisme
Neuro endocrinology letters, 2012
Cancer appears in the new form of cell life as a direct consequence of self-organising pre-cancer... more Cancer appears in the new form of cell life as a direct consequence of self-organising pre-cancer cells (dissipathogenic systems), whose further existence is disabled by extreme impairment of their metabolism. Life itself is the highest value, since instead of necrosis or apoptosis, the cellular system in an unfavourable environment can change its genetic identity provided that the improvement in its own metabolism leads to increased chaos by higher dissipation of matter and energy in its environment. Prolongation of human life has resulted by a longer period of old age which is favourable for self-organisation of dissipative neoplastic cells. Modern medicine has explained the relation of the cervical cancer to preterm births and to inadequate use of oral contraceptives and/or replacement, instead of supplementary, neurohormonal therapy. Therefore, as early as in the period of pregnancy reproductive cells should be protected due to their prime importance in the intergenerational pas...
Current Gynecologic Oncology, 2010
Acta geneticae medicae et gemellologiae, 1972
The determination of oxytocinasemia is the method of choice in monitoring multiple pregnancy. An ... more The determination of oxytocinasemia is the method of choice in monitoring multiple pregnancy. An increase in the level of the enzyme indicates a normal development of the pregnancy.Although, as a rule, the oxytocinasemia level is higher in multiple than in single pregnancy, there are cases with a level pointing to intrauterine fetal danger, if, in a gestation beyond the seventh lunar month, it is lower than 4 μmol∣l∣min.The birth of a newborn with a body weight below 2500 g, when the oxytocinasemia level exceeds 12 I.U., indicates that a multiple pregnancy is involved.
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 20, 1964
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 4, 1963
Ginekologia polska, 2003
Apgar score remains permanent conquest of medicine due its objective evaluation of available poin... more Apgar score remains permanent conquest of medicine due its objective evaluation of available point counting of the level and quickness of newborn's breathing-circulation system adaptation to the new environment. For its example the score of fetal and newborn's maturation evaluation has been described. The matter is in this so that Apgar score don't be using for evaluation of fetal maturity because it is easy to determine it directly. Of course, the higher fetal maturity level the higher probability of high Apgar score, and the quicker and better post-partum child's adaptation for independent life in new circumstances takes place.
Early pregnancy (Online), 2001
Enzymes as biochemical markers come within the entire scope of the live mother-fetus system. The ... more Enzymes as biochemical markers come within the entire scope of the live mother-fetus system. The most important are the enzymes which regulate physiological processes, of which oxytocinase (a type of aminopeptidase) has a much wider scope of action than its name suggests, as it regulates also the level of aminopeptide hypothalamic hormones. Thus, it determines neurological, endocrinological and immunological regulation of entire steroidogenesis. Under the influence of gestational enlargement of the uterine cavity, the mothers hypothalamus produces an increasing amount of hormones, which in turn induces an increasing oxytocinase synthesis in the placenta in order to prevent the hormone in the blood reaching the level which could bring about uterine contractions. Also, the growing fetus additionally induces the production of oxytocinase by releasing its own hormones. All this occurs in combined action of the mother, fetus, placenta and even fetal membranes in one space-time process ca...
Ginekologia polska, 2000
The aim of the study is to define the systemic prognostic factors in the neoplasm according to th... more The aim of the study is to define the systemic prognostic factors in the neoplasm according to thermodynamic theory of cancer a the self-organising dissipative structure. As the local, so called "specific" factors seem to be not adequate one should look for more general ones. It is shown, that such general factors as hormonal state of women' organism, preterm births, lactation, infertility treatment are important.
Polski tygodnik lekarski (Warsaw, Poland : 1960), Jan 20, 1967
La Revue française d'endocrinologie clinique, nutrition, et métabolisme