Rupam Sinha - Academia.edu (original) (raw)
Papers by Rupam Sinha
Journal of Indian Academy of Oral Medicine and Radiology
Adenoid cystic carcinoma (ADCC) is one of the malignant salivary gland neoplasm and constitutes f... more Adenoid cystic carcinoma (ADCC) is one of the malignant salivary gland neoplasm and constitutes for 1% of head and neck malignancies and 22% of all salivary gland malignancies. Palate is the most common site to be involved in the oral cavity followed by parotid region, tongue, and floor of mouth. It is commonly seen in middle age population with slight female predilection. It usually appears as asymptomatic, slow growing infiltrative growth with high recurrence, often presence of perineural invasion which appears as pain. In this present case of ADCC, a 65-year-old female patient reported with a swelling on the left side of hard palatal area since 3 months with occasional pain and history of epistaxis, which was diagnosed clinically, radiographically, and histopathologically and confirmed by immunohistochemistry as Grade III solid variety of ADCC with a poor prognosis.
Ackerman's tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral s... more Ackerman's tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.
IP International Journal of Maxillofacial Imaging, 2021
Dermatoglyphic patterns were recorded using standard ink method. The result showed in SCC, there ... more Dermatoglyphic patterns were recorded using standard ink method. The result showed in SCC, there was an increase in frequency of arch and ulnar loop patterns on fingertips, decrease in frequency of simple whorl patterns on fingertips, decrease in frequency of palmar accessory triradii on right and left hands. Significant findings in OSF included an increase in frequency of arch and ulnar loop pattern, decrease in frequency of simple whorl patterns on fingertips, decrease in ATD angle on right hand decrease in frequency of palmar accessory triradii on right hand. The results revealed that the field of dermatoglyphics holds promising results for determining the genetic susceptibility of individuals to develop SCC and OSF.
Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors oc... more Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate followed by upper lip. Surgical removal with adequate margins is the principal treatment. Due to its microscopic projections, this tumor requires a wide resection to avoid recurrence. We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature.
Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology, 2019
Parasites have always been a point of interest for the medical fraternity. They cause numerous am... more Parasites have always been a point of interest for the medical fraternity. They cause numerous amount of diseases around the globe and are of prime importance of studies of major health organisations like WHO and CDC. Hydatid cyst are one of the commonest occurring cysts affecting the world population. However the oral complications has been less studied because of its rare occurrence in that region. This review article deals with the life cycle, intra oral complications along with diagnosis and treatment of such cysts.
International Dental & Medical Journal of Advanced Research - VOLUME 2015, 2015
The modern scenario of ongoing successful organ transplantations has led to such patients present... more The modern scenario of ongoing successful organ transplantations has led to such patients presenting to their health care practitioners with oral complaints. Often these complaints are related to oral mucosal lesions or masses, which are either drug-induced or as a consequence of immunosuppression. Oral lesions in transplant recipients need to be identifi ed, diagnosed, and treated effi ciently in order to improve the quality of life and sense of well-being in these patients. This review appraises the recognition of plethora of oral problems that can arise in transplant recipients and their appropriate management by an oral physician.
Journal of Indian Academy of Oral Medicine and Radiology, 2016
Neurilemmomas are relatively uncommon lesions most commonly encountered in the nerve sheath origi... more Neurilemmomas are relatively uncommon lesions most commonly encountered in the nerve sheath originating from Schwann cells. They are rarely found in the oral cavity and are characterized by solitary occurrence, slow, persistent growth and smooth surface, along with inconsistent clinical aspects depending on the nerve origin. Microscopically, the lesion typically comprises of alternating regions of hypercellularity and hypocellularity such as Antoni A and Antoni B arrangements, respectively. Here, we present a case of a benign spindle cell tumor of the mandible reflecting a case of intraosseous neurilemmoma in a 33-year-old female patient. Immunopositivity with S-100 and vimentin clearly indicates the lesion to be a spindle cell tumor with neural involvement. The prognosis was favorable; complete surgical removal was the treatment of choice with no recurrence noted. The present case further magnifies the importance of neurilemmoma and further aids in the differential diagnosis of several other benign soft tissue tumors in the oral cavity.
Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squam... more Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.
Journal of Indian Academy of Oral Medicine and Radiology, 2018
Background: Pyogenic granuloma is a common, non-neoplastic reactive growth of the oral cavity. Tr... more Background: Pyogenic granuloma is a common, non-neoplastic reactive growth of the oral cavity. Treatment consists of conservative surgical excision, cryosurgery, or laser surgery. These are usually adequate but often result in scars and recurrence. Therefore, this study was undertaken to determine the effectiveness of sclerotherapy in the treatment of oral pyogenic granuloma. Materials and Methods: Forty clinically diagnosed cases of oral pyogenic granuloma were included in the study. After topical anesthesia application, 0.2–0.5 mL of sodium tetradecyl sulfate was delivered by insulin syringe into the base of lesions till the solution leaked out. Each patient was recalled after 1 week and evaluated. If the lesion did not resolve, second and third injections were given consecutively. Results: All the 40 patients showed complete regression of the lesion after one to four consecutive shots in weekly interval. Conclusion: Intralesional sclerotherapy can be considered as an effective non-surgical treatment procedure for oral pyogenic granuloma.
Journal of Indian Academy of Oral Medicine and Radiology, 2021
Background: Recurrent aphthous stomatitis (RAS) is a recurrent acute ulcerative lesion of oral mu... more Background: Recurrent aphthous stomatitis (RAS) is a recurrent acute ulcerative lesion of oral mucosa. Till now, the exact cause and mechanism of this condition isn't very much clear; it is however believed to be multifactorial. Various studies indicate that genetically mediated disturbances of the innate and acquired immunity play an important role in the disease development. Vitamins and micro-elements deficiencies are one of the principal factors that modify the immunologic response in RAS. Aim: To probe for correlation between serum levels of Vitamin A, B12, D3, E, and RAS. Methods and Materials: The cross-sectional clinical study was conducted on persons seeking dental service at some private dental college in West Bengal, India between January 2017 and June 2018. Forty patients suffering from RAS were compared to forty normal individuals. Applying ELISA method, serum concentration of vitamins A, vitamin B12, vitamin D3 and vitamin E were measured in two groups. Statistical Analysis: The means between two groups were compared by Student's unpaired 't' test. A value of P < 0.05 was considered as statistically significant. Results: RAS patients had a significantly lower serum level of vitamin A, B12, D3 and E than normal individuals; and there were a positive relation between the serum level of vitamin B12 and vitamin E in RAS patients. Conclusion: Vitamin A, B12, D3 and E deficiency have a significant bearing on RAS; and serum level of vitamin B12 and E of RAS patients have a significant interrelationship.
Journal of Family Medicine and Primary Care, 2018
Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters a... more Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule present on desmosomes. Histological features comprise intraepithelial cleft and Tzanck cells. Corticosteroids remain the mainstay of the treatment plan. In this article, we have discussed about the diagnosis of three patients suffering from PV, the treatment rendered, and the outcome of the same.
Journal of Family Medicine and Primary Care, 2022
Dental implants are most acceptable tool used for the prosthetic rehabilitation of edentulous are... more Dental implants are most acceptable tool used for the prosthetic rehabilitation of edentulous areas. Diagnostic images of surgical site is necessary for pre-operative treatment planning, intra-operative work assessment, and postoperative treatment evaluation. At present, cone-beam computed tomography (CBCT) is the best imaging modality for qualitative and quantitative analysis of the surgical site for implant placement. It allows proper planning and subsequent post-operative evaluation with sub-millimetric accuracy in implant placement of lower jaw considering the position of inferior alveolar nerve canal. CBCT software enables simulation of implant placement to choose the ideal dimension, position and orientation by evaluating bone quality and position of inferior alveolar nerve canal with different anatomical type and variety. This article describes why CBCT is crucial for pre-surgical assessment dental implants following position of inferior alveolar nerve canal in mandibular area.
Journal of Indian Academy of Oral Medicine and Radiology, 2017
Bifid condyle is a rare anatomic modification of mandibular condyle caused by developmental or tr... more Bifid condyle is a rare anatomic modification of mandibular condyle caused by developmental or traumatic reasons, and often diagnosed incidentally on routine radiographic examination. Eagle's syndrome (ES) occurs when an elongated styloid process or calcified stylohyoid ligament causes recurrent throat pain or foreign body sensation, dysphagia, or orofacial pain. On the other hand, Ely's cysts are focal subchondral cysts resulting from bony remodelling and osteoarthritic changes. Here, we report a case depicting an interesting combination of all the abovementioned entities in a single patient.
IP International Journal of Maxillofacial Imaging, 2021
Cenesthopathy is characterized by abnormal sensations at various parts of the body. When it occur... more Cenesthopathy is characterized by abnormal sensations at various parts of the body. When it occurs in the oral cavity it is termed as oral cenesthopathy. These patients complain of unusual sensations without corresponding abnormal findings, such as excessive mucus secretion, a slimy sensation, or a feeling of coils or wires being present within the oral cavity. They usually visit multiple dentists rather than psychiatrists and repeatedly pursue unnecessary surgical procedures to remove their 'foreign body' which sometimes creates a dilemma for the dentists. This review focuses on the various aspects of oral cenesthopathy.
Each day, every human being ingests a large number of living microorganisms, predominantly bacter... more Each day, every human being ingests a large number of living microorganisms, predominantly bacteria. Although these organisms are naturally present in food and water, they can also be deliberately added during the processing of foods such as sausages, cheese, yogurt and fermented milk products. For several decades now, bacteria called probiotics have been added to some foods because of their beneficial effects for human health. Although only a few clinical studies have been conducted so far, the results to date suggest that probiotics could be useful in preventing and treating oral infections, including dental caries, periodontal disease and halitosis. This article summarizes the currently available data on the potential benefits of probiotics for general and oral health.
Optical Coherence Tomography (OCT) is a new technology, which gives a 3 dimensional, non-invasive... more Optical Coherence Tomography (OCT) is a new technology, which gives a 3 dimensional, non-invasive imaging modality which produce high-resolution images of a biological tissues in cross section. OCT is analogous to ultrasound imaging, except that it uses light from broadband laser light source instead of sound. In the year 1991, Huang and co-workers were rst introduced OCT which was initially used for retinal imaging. Later in 1998, Colston et al were introduced OCT for dental applications. It can provide images of tissue in situ and in real time. OCT can be used where standard excisional biopsy is hazardous or impossible, to reduce sampling errors associated with excisional biopsy, and to guide interventional procedures. This review article focuses on principle and various applications in dentistry till date.
Oral cavity has a unique and diverse constitution and atmosphere. Due to its uniqueness and diver... more Oral cavity has a unique and diverse constitution and atmosphere. Due to its uniqueness and diversity, wide spectrum of diseases are encountered. Some of them may have overlapping clinical presentation, creating the diagnostic dilemma. Here a case of Heck's disease has been discussed which had an overlapping clinical picture with that of Erythroplakia.
Journal of Family Medicine and Primary Care, 2017
Muscular dystrophies are a clinically and heterogeneous group of disorders that all share clinica... more Muscular dystrophies are a clinically and heterogeneous group of disorders that all share clinical characteristics of progressive muscular weakness. Duchenne muscular dystrophy (DMD) is the most common X-linked disorder muscular dystrophy in children, presenting in early childhood and characterized by proximal muscle weakness and calf hypertrophy in affected boys. There is usually delay in motor development and eventually wheelchair confinement followed by premature death from cardiac or respiratory complications. Treatment modalities such as corticosteroid therapy and use of intermittent positive pressure ventilation have provided improvements in function, ambulation, quality of life, and life expectancy, although novel therapies still aim to provide a cure for this devastating disorder. Here, we present a case of DMD in a 12-year-old male with remarkable clinical and oral manifestations.
Journal of Indian Academy of Oral Medicine and Radiology
Adenoid cystic carcinoma (ADCC) is one of the malignant salivary gland neoplasm and constitutes f... more Adenoid cystic carcinoma (ADCC) is one of the malignant salivary gland neoplasm and constitutes for 1% of head and neck malignancies and 22% of all salivary gland malignancies. Palate is the most common site to be involved in the oral cavity followed by parotid region, tongue, and floor of mouth. It is commonly seen in middle age population with slight female predilection. It usually appears as asymptomatic, slow growing infiltrative growth with high recurrence, often presence of perineural invasion which appears as pain. In this present case of ADCC, a 65-year-old female patient reported with a swelling on the left side of hard palatal area since 3 months with occasional pain and history of epistaxis, which was diagnosed clinically, radiographically, and histopathologically and confirmed by immunohistochemistry as Grade III solid variety of ADCC with a poor prognosis.
Ackerman's tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral s... more Ackerman's tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.
IP International Journal of Maxillofacial Imaging, 2021
Dermatoglyphic patterns were recorded using standard ink method. The result showed in SCC, there ... more Dermatoglyphic patterns were recorded using standard ink method. The result showed in SCC, there was an increase in frequency of arch and ulnar loop patterns on fingertips, decrease in frequency of simple whorl patterns on fingertips, decrease in frequency of palmar accessory triradii on right and left hands. Significant findings in OSF included an increase in frequency of arch and ulnar loop pattern, decrease in frequency of simple whorl patterns on fingertips, decrease in ATD angle on right hand decrease in frequency of palmar accessory triradii on right hand. The results revealed that the field of dermatoglyphics holds promising results for determining the genetic susceptibility of individuals to develop SCC and OSF.
Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors oc... more Pleomorphic adenoma is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common site for pleomorphic adenoma of the minor salivary glands is the palate followed by upper lip. Surgical removal with adequate margins is the principal treatment. Due to its microscopic projections, this tumor requires a wide resection to avoid recurrence. We report a case of pleomorphic adenoma in the upper lip of an elderly female with emphasis on differential diagnosis and relevant review of literature.
Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology, 2019
Parasites have always been a point of interest for the medical fraternity. They cause numerous am... more Parasites have always been a point of interest for the medical fraternity. They cause numerous amount of diseases around the globe and are of prime importance of studies of major health organisations like WHO and CDC. Hydatid cyst are one of the commonest occurring cysts affecting the world population. However the oral complications has been less studied because of its rare occurrence in that region. This review article deals with the life cycle, intra oral complications along with diagnosis and treatment of such cysts.
International Dental & Medical Journal of Advanced Research - VOLUME 2015, 2015
The modern scenario of ongoing successful organ transplantations has led to such patients present... more The modern scenario of ongoing successful organ transplantations has led to such patients presenting to their health care practitioners with oral complaints. Often these complaints are related to oral mucosal lesions or masses, which are either drug-induced or as a consequence of immunosuppression. Oral lesions in transplant recipients need to be identifi ed, diagnosed, and treated effi ciently in order to improve the quality of life and sense of well-being in these patients. This review appraises the recognition of plethora of oral problems that can arise in transplant recipients and their appropriate management by an oral physician.
Journal of Indian Academy of Oral Medicine and Radiology, 2016
Neurilemmomas are relatively uncommon lesions most commonly encountered in the nerve sheath origi... more Neurilemmomas are relatively uncommon lesions most commonly encountered in the nerve sheath originating from Schwann cells. They are rarely found in the oral cavity and are characterized by solitary occurrence, slow, persistent growth and smooth surface, along with inconsistent clinical aspects depending on the nerve origin. Microscopically, the lesion typically comprises of alternating regions of hypercellularity and hypocellularity such as Antoni A and Antoni B arrangements, respectively. Here, we present a case of a benign spindle cell tumor of the mandible reflecting a case of intraosseous neurilemmoma in a 33-year-old female patient. Immunopositivity with S-100 and vimentin clearly indicates the lesion to be a spindle cell tumor with neural involvement. The prognosis was favorable; complete surgical removal was the treatment of choice with no recurrence noted. The present case further magnifies the importance of neurilemmoma and further aids in the differential diagnosis of several other benign soft tissue tumors in the oral cavity.
Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squam... more Ackerman’s tumour commonly known as Verrucous carcinoma (VC) is a low grade variant of oral squamous cell carcinoma (OSCC). The oral cavity and larynx have been reported to be the commonest sites of involvement in the head and neck regions. VC is characterised with presence of minimal degree of dysplasia and biological aggressiveness, the principal etiological factor being tobacco usage. Its distinctive histopathological features make it exigent for diagnosis and build a close association between the clinician and the histopathologist. Hereby we report a rare case of verrucous carcinoma on the right buccal mucosa of a 48 year old male patient progressing into invasive squamous cell carcinoma.
Journal of Indian Academy of Oral Medicine and Radiology, 2018
Background: Pyogenic granuloma is a common, non-neoplastic reactive growth of the oral cavity. Tr... more Background: Pyogenic granuloma is a common, non-neoplastic reactive growth of the oral cavity. Treatment consists of conservative surgical excision, cryosurgery, or laser surgery. These are usually adequate but often result in scars and recurrence. Therefore, this study was undertaken to determine the effectiveness of sclerotherapy in the treatment of oral pyogenic granuloma. Materials and Methods: Forty clinically diagnosed cases of oral pyogenic granuloma were included in the study. After topical anesthesia application, 0.2–0.5 mL of sodium tetradecyl sulfate was delivered by insulin syringe into the base of lesions till the solution leaked out. Each patient was recalled after 1 week and evaluated. If the lesion did not resolve, second and third injections were given consecutively. Results: All the 40 patients showed complete regression of the lesion after one to four consecutive shots in weekly interval. Conclusion: Intralesional sclerotherapy can be considered as an effective non-surgical treatment procedure for oral pyogenic granuloma.
Journal of Indian Academy of Oral Medicine and Radiology, 2021
Background: Recurrent aphthous stomatitis (RAS) is a recurrent acute ulcerative lesion of oral mu... more Background: Recurrent aphthous stomatitis (RAS) is a recurrent acute ulcerative lesion of oral mucosa. Till now, the exact cause and mechanism of this condition isn't very much clear; it is however believed to be multifactorial. Various studies indicate that genetically mediated disturbances of the innate and acquired immunity play an important role in the disease development. Vitamins and micro-elements deficiencies are one of the principal factors that modify the immunologic response in RAS. Aim: To probe for correlation between serum levels of Vitamin A, B12, D3, E, and RAS. Methods and Materials: The cross-sectional clinical study was conducted on persons seeking dental service at some private dental college in West Bengal, India between January 2017 and June 2018. Forty patients suffering from RAS were compared to forty normal individuals. Applying ELISA method, serum concentration of vitamins A, vitamin B12, vitamin D3 and vitamin E were measured in two groups. Statistical Analysis: The means between two groups were compared by Student's unpaired 't' test. A value of P < 0.05 was considered as statistically significant. Results: RAS patients had a significantly lower serum level of vitamin A, B12, D3 and E than normal individuals; and there were a positive relation between the serum level of vitamin B12 and vitamin E in RAS patients. Conclusion: Vitamin A, B12, D3 and E deficiency have a significant bearing on RAS; and serum level of vitamin B12 and E of RAS patients have a significant interrelationship.
Journal of Family Medicine and Primary Care, 2018
Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters a... more Pemphigus vulgaris (PV) is an autoimmune, potentially life-threatening disease causing blisters and erosions of the skin and mucous membranes associated with intraepithelial acantholysis. The underlying mechanism responsible for causing intraepithelial lesions is the binding of immunoglobulin G autoantibodies to desmoglein 3, a transmembrane glycoprotein adhesion molecule present on desmosomes. Histological features comprise intraepithelial cleft and Tzanck cells. Corticosteroids remain the mainstay of the treatment plan. In this article, we have discussed about the diagnosis of three patients suffering from PV, the treatment rendered, and the outcome of the same.
Journal of Family Medicine and Primary Care, 2022
Dental implants are most acceptable tool used for the prosthetic rehabilitation of edentulous are... more Dental implants are most acceptable tool used for the prosthetic rehabilitation of edentulous areas. Diagnostic images of surgical site is necessary for pre-operative treatment planning, intra-operative work assessment, and postoperative treatment evaluation. At present, cone-beam computed tomography (CBCT) is the best imaging modality for qualitative and quantitative analysis of the surgical site for implant placement. It allows proper planning and subsequent post-operative evaluation with sub-millimetric accuracy in implant placement of lower jaw considering the position of inferior alveolar nerve canal. CBCT software enables simulation of implant placement to choose the ideal dimension, position and orientation by evaluating bone quality and position of inferior alveolar nerve canal with different anatomical type and variety. This article describes why CBCT is crucial for pre-surgical assessment dental implants following position of inferior alveolar nerve canal in mandibular area.
Journal of Indian Academy of Oral Medicine and Radiology, 2017
Bifid condyle is a rare anatomic modification of mandibular condyle caused by developmental or tr... more Bifid condyle is a rare anatomic modification of mandibular condyle caused by developmental or traumatic reasons, and often diagnosed incidentally on routine radiographic examination. Eagle's syndrome (ES) occurs when an elongated styloid process or calcified stylohyoid ligament causes recurrent throat pain or foreign body sensation, dysphagia, or orofacial pain. On the other hand, Ely's cysts are focal subchondral cysts resulting from bony remodelling and osteoarthritic changes. Here, we report a case depicting an interesting combination of all the abovementioned entities in a single patient.
IP International Journal of Maxillofacial Imaging, 2021
Cenesthopathy is characterized by abnormal sensations at various parts of the body. When it occur... more Cenesthopathy is characterized by abnormal sensations at various parts of the body. When it occurs in the oral cavity it is termed as oral cenesthopathy. These patients complain of unusual sensations without corresponding abnormal findings, such as excessive mucus secretion, a slimy sensation, or a feeling of coils or wires being present within the oral cavity. They usually visit multiple dentists rather than psychiatrists and repeatedly pursue unnecessary surgical procedures to remove their 'foreign body' which sometimes creates a dilemma for the dentists. This review focuses on the various aspects of oral cenesthopathy.
Each day, every human being ingests a large number of living microorganisms, predominantly bacter... more Each day, every human being ingests a large number of living microorganisms, predominantly bacteria. Although these organisms are naturally present in food and water, they can also be deliberately added during the processing of foods such as sausages, cheese, yogurt and fermented milk products. For several decades now, bacteria called probiotics have been added to some foods because of their beneficial effects for human health. Although only a few clinical studies have been conducted so far, the results to date suggest that probiotics could be useful in preventing and treating oral infections, including dental caries, periodontal disease and halitosis. This article summarizes the currently available data on the potential benefits of probiotics for general and oral health.
Optical Coherence Tomography (OCT) is a new technology, which gives a 3 dimensional, non-invasive... more Optical Coherence Tomography (OCT) is a new technology, which gives a 3 dimensional, non-invasive imaging modality which produce high-resolution images of a biological tissues in cross section. OCT is analogous to ultrasound imaging, except that it uses light from broadband laser light source instead of sound. In the year 1991, Huang and co-workers were rst introduced OCT which was initially used for retinal imaging. Later in 1998, Colston et al were introduced OCT for dental applications. It can provide images of tissue in situ and in real time. OCT can be used where standard excisional biopsy is hazardous or impossible, to reduce sampling errors associated with excisional biopsy, and to guide interventional procedures. This review article focuses on principle and various applications in dentistry till date.
Oral cavity has a unique and diverse constitution and atmosphere. Due to its uniqueness and diver... more Oral cavity has a unique and diverse constitution and atmosphere. Due to its uniqueness and diversity, wide spectrum of diseases are encountered. Some of them may have overlapping clinical presentation, creating the diagnostic dilemma. Here a case of Heck's disease has been discussed which had an overlapping clinical picture with that of Erythroplakia.
Journal of Family Medicine and Primary Care, 2017
Muscular dystrophies are a clinically and heterogeneous group of disorders that all share clinica... more Muscular dystrophies are a clinically and heterogeneous group of disorders that all share clinical characteristics of progressive muscular weakness. Duchenne muscular dystrophy (DMD) is the most common X-linked disorder muscular dystrophy in children, presenting in early childhood and characterized by proximal muscle weakness and calf hypertrophy in affected boys. There is usually delay in motor development and eventually wheelchair confinement followed by premature death from cardiac or respiratory complications. Treatment modalities such as corticosteroid therapy and use of intermittent positive pressure ventilation have provided improvements in function, ambulation, quality of life, and life expectancy, although novel therapies still aim to provide a cure for this devastating disorder. Here, we present a case of DMD in a 12-year-old male with remarkable clinical and oral manifestations.