Samuel Brito - Academia.edu (original) (raw)
Papers by Samuel Brito
Search for B 0 s → µ + µ − and B 0 → µ + µ − decays in pp collisions at √ s = 7 TeV
Journal of The Electrochemical Society, 2007
Obesity Surgery, 2004
Background: In the last decade, laparoscopic surgery for morbid obesity has become widely employe... more Background: In the last decade, laparoscopic surgery for morbid obesity has become widely employed, including a marked increase in the placement of adjustable gastric bands (AGB). Among the co-morbidities of morbid obesity is cholelithiasis. The question arises whether concomitant cholecystectomy increases the risk of postoperative infectious complications due to the association of a potentially contaminated procedure with a clean operation, placement of an AGB. The aim of this study is to evaluate the postoperative outcome in patients submitted to laparoscopic AGB with cholecystectomy. Methods: From January 2000 to January 2004, 308 patients (85 men and 223 women) had AGB placed. BMI ranged from 38.9 to 65.6 kg/m2 (mean 41.6). In 17 patients (5.5%), gallstones were detected by ultrasonography, and cholecystectomy was performed together with the AGB. Mean operative time for placement of the AGB was 58 ± 18 min, and in those with cholecystectomy 86 ± 17min (P =0.20). Results: All patients that had placement of AGB and cholecystectomy had satisfactory postoperative outcome. No infectious complications were observed. Conclusion: Laparoscopic cholecystectomy performed simultaneously with placement of an AGB has been a safe procedure.
Fundamentos: A síndrome metabólica (SM) está relacionada com eventos cardiovasculares. Não está e... more Fundamentos: A síndrome metabólica (SM) está relacionada com eventos cardiovasculares. Não está estabelecida a relação entre SM e insuficiência cardíaca (IC) nos pacientes de área rural. Objetivo: Estudar a relação entre insuficiência cardíaca e síndrome metabólica em pacientes de área rural. Métodos: Estudo transversal, incluindo 83 pacientes com IC de área rural na cidade de Valença (RJ), com acompanhamento médio de 8,3±2 meses. Os dados coletados incluíram aspectos clínicos, eletrocardiográficos e ecocardiográficos. SM foi definida de acordo com o critério NCEP-ATPIII. A análise estatística foi realizada com ajuda do software SPSS 9.0, sendo considerada significância estatística um p<0,05. Resultados: Dos 83 pacientes com IC, 52 (63%) apresentavam critérios para SM (p=0,001), sendo 31 (60%) do sexo feminino (razão de chance [RC] de 3,1; IC1, 21-7,89; p<0,02). Na análise dos componentes da SM não se verificou diferença significativa entre os pacientes com IC com fração de ejeção preservada (ICFEP) e IC com fração de ejeção deprimida (ICFED). Os pacientes com ICFED (n=17 50%) apresentavam mais sobrepeso do que os pacientes com ICFEP (p<0,04). Foi observada uma maior prevalência de ICFEP no sexo feminino (p<0,0001) e naqueles não-pretos (p<0,0001). Quanto às comorbidades (tabagismo, doença arterial coronariana, insuficiência renal crônica, anemia e fibrilação atrial) não houve diferença entre os grupos. Em relação aos sintomas, os pacientes com ICFED se apresentavam mais em NYHA III (n=10 (29%) p<0,02). Conclusão: A síndrome metabólica apresenta elevada prevalência em pacientes de área rural, com IC, sendo Abstract Background: The metabolic syndrome (MS) is related with cardiovascular events. The association of MS in HF patients has not been established in patients from rural area. Objective: To study the relationship between heart failure and metabolic syndrome in patients from rural area in Rio de Janeiro State, Brasil Methods: We performed a cross-sectional study that included 83 patients with CHF from rural area in the city of Valença -Rio de Janeiro they have an average accompaniment of 8.3±2 months. The data had been collected through clinical criteria, electrocardiographic and echocardiogram. The metabolic syndrome was defined in according to NCEP-ATPIII. The statistical analysis was performed using software SPSS 9.0 and p<0.05 were considered statistically significance. Results: From 83 patients with HF, 52 (63%) presented criteria for MS (p=0.001), of which 31 (60%) were females (odds ratio [OR] of 3.1; confidence interval [CI] 1.21-7.89; p<0.02). The analysis of the components of the MS didn't verify significant difference among the patients HF with preserved ejection fraction (HFPEF) and HF with depressed ejection fraction (HFDEF). The patients with HFDEF (n=17 50%) presented more overweight 17 (50%) in relation to the patients with HFPEF (p<0.04). It was observed major prevalence of HFPEF in female (p<0.0001) and also in not black (p<0.0001). Related with comorbidities (smoking, coronary arterial disease, chronic kidney disease, anemia and atrial fibrillation) didn't have any difference between the groups. In relation to symptoms, patients with HFDEF were more inserted in NYHA III n=10, (29%) p<0.02.
Journal of The American College of Cardiology, 1995
Presently, there is no effective drug or device therapy to reduce coronary restenosis after angio... more Presently, there is no effective drug or device therapy to reduce coronary restenosis after angioplasty, There is now evidence that low dose radiation inhibits the process of intimal hyperplasia and prevents restenosis in the coronary porcine model and in the superficial femoral artery in humans, On July 28, 1994, the first precision dose of radiation therapy was delivered percutaneously into the human coronary artery. It is the intent of this investigation to determine if immediate low dose ICRT delivered directly to the angioplasty site will prevent the subsequent development of restenosis.10 patients (8 male & 2 female) from age 36 to 66 (average age of 52) with clinical ischemic heart disease (angina and transient ST segment abnormalities) underwent PTCA-ICRT. 13 coronary segments in 11 arteries were treated consisting of 85% (11/13) Type B and 15% (2/13) Type C lesions. The anatomy of the lesions consisted of 45% (5/11) left anterior descending artery, 27% (3/11) right coronary artery, 18% (2/11) left circumflex artery, and 9% (1/11) ramus intermedius artery. Standard periprocedural therapy included aspirin, heparin, intracoronary nitroglycerin, and calcium channel antagonists. An Iridium 192 source wire was afterloaded through a coronary catheter system. The source wire was positioned at the angioplasty site by measurement and by direct fluoroscopic visualization. A treatment dose of 2000 cGy was delivered to the intima of each coronary artery segment. The treatment times ranged from 5 to 15 minutes. The procedure was well tolerated. Slight chest pain was experienced by 2 patients. Mild spasm occurred in 8 of 11 treated coronary arteries which responded well to intracoronary nitroglycerin. Angiography performed immediately and 24 hours after PTCA-ICRT demonstrated that all treated coronary segments were widely patent. Continued follow-up and patient accrual are planned. All patients will be re-angiogramed 6 months after PTCA-ICRT.lntracoronary Radiation Therapy can now be delivered safely and it is our hope that in the near future our expanding clinical study will demonstrate the efficacy of ICRT in reducing coronary restenosis.
Obesity Surgery, 2004
Background: About 15% of patients who undergo adjustable gastric banding (AGB) have difficulty lo... more Background: About 15% of patients who undergo adjustable gastric banding (AGB) have difficulty losing weight due to, among other factors, the development or maintenance of binge eating disorder. Topiramate is an anticonvulsive drug with proven good results in controlling binge eating episodes. The objective of this study was to analyze the effect of topiramate in patients with AGB. Methods: 16 patients with binge eating and inadequate weight loss after AGB were analyzed prospectively for 3 months while receiving topiramate in doses varying from 12.5 to 50 mg per day. Results: There was a mean increase in excess weight loss from 20.4% to 34.1% without the need for band readjustment. 2 patients had intolerance to topiramate and were changed to fluoxetine 40 mg per day. Conclusion: Topiramate may be a useful adjuvant for patients with AGB and binge eating disorder.
Curtis's Botanical Magazine, 1996
Summary. Previously unpublished paintings of Brazilian orchids by Barbosa Rodrigues are to be res... more Summary. Previously unpublished paintings of Brazilian orchids by Barbosa Rodrigues are to be restored and published as Iconographie des Orchidées du Brésil.
Biocontrol Science and Technology, 2008
Dengue fever vectored by the mosquito Aedes aegypti is one of the most rapidly spreading insect-b... more Dengue fever vectored by the mosquito Aedes aegypti is one of the most rapidly spreading insect-borne diseases, stimulating the search for alternatives to current control methods. Screening assays using a range of Metarhizium anisopliae and Beauveria bassiana isolates were ...
Neotropical Biology and Conservation, 2010
Epiperipatus cratensis sp. nov. (Onychophora: Peripatidae) from northeastern Brazil Uma nova espé... more Epiperipatus cratensis sp. nov. (Onychophora: Peripatidae) from northeastern Brazil Uma nova espécie de Epiperipatus (Onychophora: Peripatidae) da região nordeste do Brasil Abstract This article aims to describe and illustrate Epiperipatus cratensis sp. nov. from Crato (coordinates 07°16'S,39°26'W), Ceará State, Brazil. Specimens of onychophorans were collected under stones and decomposing tree barks during the rainy season. E. cratensis differs from all of the species of the genus by having: (i) many pairs of legs, even though it is the second smallest species in size to the genus in Brazil; (ii) fewer rings of antennas than the other Brazilian species. Furthermore, E. cratensis is similar to E. tucupi, especially because females have 34 pairs of legs, and differs morphologically only by being shorter in size. In addition, this two species are located in different biomes: E. tucupi is endemic to the Amazon region, while E. cratensis is derived from Chapada do Araripe mountains, within Atlantic Forest biome of the Brejos de Altitude complex of northeastern Brazil.
Journal of Ethnobiology and Ethnomedicine, 2009
Background Animals have been used as a source of medicine in Brazil since ancient times, and have... more Background Animals have been used as a source of medicine in Brazil since ancient times, and have played a significant role in healing practices. Specifically in Northeast Brazil, zootherapy is a very common practice, and together with medicinal plants, it plays an important role as a therapeutic alternative. In the state of Ceara, no works have been carried out on rural communities with regard to use of zootherapeutics, even though the practice of zootherapy is common in this region. Therefore, the aim of this study was to analyze the use of medicinal animals in a rural community (Poco Dantas) in the municipality of Crato, Ceara, Brazil. Methods The field survey was carried out from October 2008 to January 2009 by conducting interviews using structured questionnaires with 72 people (33 men and 39 women), who provided information on animal species used as remedies, body parts used to prepare the remedies, and ailments for which the remedies were prescribed. We calculated the informant consensus factor (ICF) to determine the consensus over which species are effective for particular ailments, as well as the species use value (UV) to determine the extent of utilization of each species. Results A total of 29 species, distributed in 17 families were categorized as having some medicinal property. The taxa most represented were: mammals (9), insects (7), reptiles and birds (4). Progne chalybea, a species not previously recorded as being of medicinal use, was cited in the present work, where it is utilized in the treatment of alcoholism. The animals are used in the treatment of 34 diseases or symptoms, where sore throat, inflammations and cough are the ailments with the greatest number of citations. Conclusion The data show that zootherapy represents an important therapeutic alternative for the inhabitants of the community. New studies on medicinal fauna should be conducted with the aim of determining the exploitation level of the species utilized, promoting sustainable development of medicinal species that are eventually threatened, and preserving and disseminating the knowledge developed by traditional individuals of the community.
Brazilian Journal of Biology, 2006
Espécies de Porocephalus (Pentastomida) infectando Boa constrictor (Boidae) e Lachesis muta (Vipe... more Espécies de Porocephalus (Pentastomida) infectando Boa constrictor (Boidae) e Lachesis muta (Viperidae) na Região Nordeste do Brasil. O Brasil possui uma grande diversidade de cobras, mas há poucos trabalhos realizados sobre parasitismo destas por pentastomídeos. No intuito de investigar o parasitismo pulmonar por pentastomídeos em grandes cobras na região nordeste, foram examinados seis espécimes de Boa constrictor e duas de Lachesis muta pertencentes à coleção do Serpentário da Universidade Federal de Pernambuco -UFPE, todos coletadas em localidades de mata úmida (Mata Atlântica). Apenas um espécime de B. constrictor estava infectado por Porocephalus sp. (intensidade de infecção 5,0). Apenas um espécime de L. muta estava infectado por P. stilesi (intensidade de infecção 15,0).
Brazilian Journal of Biology, 2006
Cephalobaenidae constitutes one of the main pentastomid groups infecting the respiratory tract of... more Cephalobaenidae constitutes one of the main pentastomid groups infecting the respiratory tract of snakes. Six specimens of Liophis lineatus, a colubrid, were collected by active capture and pitfalls installed on the banks of the Batateiras river, close to its source, in the APA Área de Proteção Ambiental (a protected environmental area of the IBAMA Brazilian Institute for the Environment and Natural Resources), and in a remnant of the humid tropical forest FLONA Floresta Nacional do Araripe, both in the municipality of Crato, state of Ceará, Northeast Brazil. Out of the six specimens of L. lineatus examined, only one had its lung infected by the pentastomid Cephalobaena tetrapoda. This represents the first record of C. tetrapoda as a parasite of a snake in Northeast Brazil, as well as the first record of a colubrid, L. lineatus, as a new host for the pentastomid in Brazil.
Journal of Ethnopharmacology, 2010
Tupinambis merianae is one of the most frequently used animals in traditional medicine in Brazil ... more Tupinambis merianae is one of the most frequently used animals in traditional medicine in Brazil as its body fat has many different therapeutic indications as a folk remedy. The present study evaluated the topical anti-inflammatory activity of Tupinambis merianae fat in treating ear edema in an animal model.Oil (OTM) was extracted from body fat located in the ventral region of Tupinambis merianae using hexane as a solvent. Ear edema provoked by the application of croton oil (single and multiple application), arachidonic acid, phenol and capsaicin to Swiss mice was used to evaluate the potential anti-inflammatory value of the topical use of OTM. Topical applications of these irritants were made to the right ears of animals that were pre-treated with a acetone (control), dexamethasone, or OTM.Our results indicate that Tupinambis merianae fat demonstrates significant topical anti-inflammatory activity that reduces inflammation related to ear edema caused by croton oil (single and multiple application), arachidonic acid, phenol. While the inflammation caused by capsaicin, OTM did not significantly reduce the edema.This represents the first evidence of anti-inflammatory activity of Tupinambis merianae fat in in vivo models, confirming its usefulness in traditional medicine as a remedy for skin diseases (dermatitis). The fatty acids present in OTM most likely inhibit the response pathway of arachidonic acid and its metabolites, thus reducing the production of pro-inflammatory mediators.
BMC Complementary and Alternative Medicine, 2009
Background: Human communities consistently develop a detailed knowledge of the therapeutical and ... more Background: Human communities consistently develop a detailed knowledge of the therapeutical and medicinal properties of the local flora and fauna, and these folk remedies often substitute medicines produced by the pharmaceutical industry. Animals (and their derived products) are essential ingredients in the preparation of many traditional remedies. The present work prepared an inventory of the animals sold in public markets in the cities of Crato and Juazeiro do Norte, Ceará State, Brazil.
Journal of Ethnopharmacology, 2009
Tupinambis merianae is one of the animals that is most frequently used for medicinal purposes in ... more Tupinambis merianae is one of the animals that is most frequently used for medicinal purposes in Brazil as its body fat has many therapeutic indications in local folk medicine. This work presents the chemical compositions of the body fat of Tupinambis merianae and evaluates the antibacterial activity of the body fat as well as the ecological implications of its use in traditional medicine.Oil (OTM) was extracted from body fat located in the ventral region of Tupinambis merianae using hexane as a solvent. Fatty acids were determined indirectly using their corresponding methyl esters. The antibacterial activity of OTM was tested against standard as well as multi-resistant lines of Escherichia coli and Staphylococcus aureus, either alone or in combination with antibiotics and UV-A light.Body fat of Tupinambis merianae presents 57% and 43% of unsaturated and saturated fatty acids respectively. Our results indicated that OTM did not demonstrate relevant antibacterial activity against any of the lines of Escherichia coli or Staphylococcus aureus, nor when combined with antibiotics or with UV-A light.In light of these results, we recommend (i) development of management plans for a sustainable and rational use of Tupinambis merianae reducing the possible pressure on this species; and (ii) more studies be focused on the use of OTM and other natural products derived from animals that are used to treat other illnesses.
Natural Product Research, 2012
In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacteria... more In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacterial activity against multiresistant strains of Escherichia coli and Staphylococcus aureus. The antibacterial and modulatory activity of the extracts was assayed by microdilution. The light-enhanced antibacterial activity was assayed by light regimen. The growth of the bacteria tested was not inhibited by the extracts. The minimum inhibitory concentration (MIC) values ranged from 512 to ≥1024 µg · m L−1. However, the antibiotic activity of the aminoglycosides was synergistically enhanced when these extracts were associated in sub-inhibitory concentrations with the antibiotics. Both extracts showed activity against at two standard bacterial strains. Because of this, we suggest that the ethanol extracts of the stems and leaves of Costus cf. arabicus L. show potential antibacterial, light-induced and synergistic antibiotic activity. With such results, these extracts are proven to be a promising source of antibacterial and modulatory agents.
Natural Product Research, 2011
In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacteria... more In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacterial activity against multiresistant strains of Escherichia coli and Staphylococcus aureus. The antibacterial and modulatory activity of the extracts was assayed by microdilution. The light-enhanced antibacterial activity was assayed by light regimen. The growth of the bacteria tested was not inhibited by the extracts. The minimum inhibitory concentration (MIC) values ranged from 512 to ≥1024 µg · m L−1. However, the antibiotic activity of the aminoglycosides was synergistically enhanced when these extracts were associated in sub-inhibitory concentrations with the antibiotics. Both extracts showed activity against at two standard bacterial strains. Because of this, we suggest that the ethanol extracts of the stems and leaves of Costus cf. arabicus L. show potential antibacterial, light-induced and synergistic antibiotic activity. With such results, these extracts are proven to be a promising source of antibacterial and modulatory agents.
Search for B 0 s → µ + µ − and B 0 → µ + µ − decays in pp collisions at √ s = 7 TeV
Journal of The Electrochemical Society, 2007
Obesity Surgery, 2004
Background: In the last decade, laparoscopic surgery for morbid obesity has become widely employe... more Background: In the last decade, laparoscopic surgery for morbid obesity has become widely employed, including a marked increase in the placement of adjustable gastric bands (AGB). Among the co-morbidities of morbid obesity is cholelithiasis. The question arises whether concomitant cholecystectomy increases the risk of postoperative infectious complications due to the association of a potentially contaminated procedure with a clean operation, placement of an AGB. The aim of this study is to evaluate the postoperative outcome in patients submitted to laparoscopic AGB with cholecystectomy. Methods: From January 2000 to January 2004, 308 patients (85 men and 223 women) had AGB placed. BMI ranged from 38.9 to 65.6 kg/m2 (mean 41.6). In 17 patients (5.5%), gallstones were detected by ultrasonography, and cholecystectomy was performed together with the AGB. Mean operative time for placement of the AGB was 58 ± 18 min, and in those with cholecystectomy 86 ± 17min (P =0.20). Results: All patients that had placement of AGB and cholecystectomy had satisfactory postoperative outcome. No infectious complications were observed. Conclusion: Laparoscopic cholecystectomy performed simultaneously with placement of an AGB has been a safe procedure.
Fundamentos: A síndrome metabólica (SM) está relacionada com eventos cardiovasculares. Não está e... more Fundamentos: A síndrome metabólica (SM) está relacionada com eventos cardiovasculares. Não está estabelecida a relação entre SM e insuficiência cardíaca (IC) nos pacientes de área rural. Objetivo: Estudar a relação entre insuficiência cardíaca e síndrome metabólica em pacientes de área rural. Métodos: Estudo transversal, incluindo 83 pacientes com IC de área rural na cidade de Valença (RJ), com acompanhamento médio de 8,3±2 meses. Os dados coletados incluíram aspectos clínicos, eletrocardiográficos e ecocardiográficos. SM foi definida de acordo com o critério NCEP-ATPIII. A análise estatística foi realizada com ajuda do software SPSS 9.0, sendo considerada significância estatística um p<0,05. Resultados: Dos 83 pacientes com IC, 52 (63%) apresentavam critérios para SM (p=0,001), sendo 31 (60%) do sexo feminino (razão de chance [RC] de 3,1; IC1, 21-7,89; p<0,02). Na análise dos componentes da SM não se verificou diferença significativa entre os pacientes com IC com fração de ejeção preservada (ICFEP) e IC com fração de ejeção deprimida (ICFED). Os pacientes com ICFED (n=17 50%) apresentavam mais sobrepeso do que os pacientes com ICFEP (p<0,04). Foi observada uma maior prevalência de ICFEP no sexo feminino (p<0,0001) e naqueles não-pretos (p<0,0001). Quanto às comorbidades (tabagismo, doença arterial coronariana, insuficiência renal crônica, anemia e fibrilação atrial) não houve diferença entre os grupos. Em relação aos sintomas, os pacientes com ICFED se apresentavam mais em NYHA III (n=10 (29%) p<0,02). Conclusão: A síndrome metabólica apresenta elevada prevalência em pacientes de área rural, com IC, sendo Abstract Background: The metabolic syndrome (MS) is related with cardiovascular events. The association of MS in HF patients has not been established in patients from rural area. Objective: To study the relationship between heart failure and metabolic syndrome in patients from rural area in Rio de Janeiro State, Brasil Methods: We performed a cross-sectional study that included 83 patients with CHF from rural area in the city of Valença -Rio de Janeiro they have an average accompaniment of 8.3±2 months. The data had been collected through clinical criteria, electrocardiographic and echocardiogram. The metabolic syndrome was defined in according to NCEP-ATPIII. The statistical analysis was performed using software SPSS 9.0 and p<0.05 were considered statistically significance. Results: From 83 patients with HF, 52 (63%) presented criteria for MS (p=0.001), of which 31 (60%) were females (odds ratio [OR] of 3.1; confidence interval [CI] 1.21-7.89; p<0.02). The analysis of the components of the MS didn't verify significant difference among the patients HF with preserved ejection fraction (HFPEF) and HF with depressed ejection fraction (HFDEF). The patients with HFDEF (n=17 50%) presented more overweight 17 (50%) in relation to the patients with HFPEF (p<0.04). It was observed major prevalence of HFPEF in female (p<0.0001) and also in not black (p<0.0001). Related with comorbidities (smoking, coronary arterial disease, chronic kidney disease, anemia and atrial fibrillation) didn't have any difference between the groups. In relation to symptoms, patients with HFDEF were more inserted in NYHA III n=10, (29%) p<0.02.
Journal of The American College of Cardiology, 1995
Presently, there is no effective drug or device therapy to reduce coronary restenosis after angio... more Presently, there is no effective drug or device therapy to reduce coronary restenosis after angioplasty, There is now evidence that low dose radiation inhibits the process of intimal hyperplasia and prevents restenosis in the coronary porcine model and in the superficial femoral artery in humans, On July 28, 1994, the first precision dose of radiation therapy was delivered percutaneously into the human coronary artery. It is the intent of this investigation to determine if immediate low dose ICRT delivered directly to the angioplasty site will prevent the subsequent development of restenosis.10 patients (8 male & 2 female) from age 36 to 66 (average age of 52) with clinical ischemic heart disease (angina and transient ST segment abnormalities) underwent PTCA-ICRT. 13 coronary segments in 11 arteries were treated consisting of 85% (11/13) Type B and 15% (2/13) Type C lesions. The anatomy of the lesions consisted of 45% (5/11) left anterior descending artery, 27% (3/11) right coronary artery, 18% (2/11) left circumflex artery, and 9% (1/11) ramus intermedius artery. Standard periprocedural therapy included aspirin, heparin, intracoronary nitroglycerin, and calcium channel antagonists. An Iridium 192 source wire was afterloaded through a coronary catheter system. The source wire was positioned at the angioplasty site by measurement and by direct fluoroscopic visualization. A treatment dose of 2000 cGy was delivered to the intima of each coronary artery segment. The treatment times ranged from 5 to 15 minutes. The procedure was well tolerated. Slight chest pain was experienced by 2 patients. Mild spasm occurred in 8 of 11 treated coronary arteries which responded well to intracoronary nitroglycerin. Angiography performed immediately and 24 hours after PTCA-ICRT demonstrated that all treated coronary segments were widely patent. Continued follow-up and patient accrual are planned. All patients will be re-angiogramed 6 months after PTCA-ICRT.lntracoronary Radiation Therapy can now be delivered safely and it is our hope that in the near future our expanding clinical study will demonstrate the efficacy of ICRT in reducing coronary restenosis.
Obesity Surgery, 2004
Background: About 15% of patients who undergo adjustable gastric banding (AGB) have difficulty lo... more Background: About 15% of patients who undergo adjustable gastric banding (AGB) have difficulty losing weight due to, among other factors, the development or maintenance of binge eating disorder. Topiramate is an anticonvulsive drug with proven good results in controlling binge eating episodes. The objective of this study was to analyze the effect of topiramate in patients with AGB. Methods: 16 patients with binge eating and inadequate weight loss after AGB were analyzed prospectively for 3 months while receiving topiramate in doses varying from 12.5 to 50 mg per day. Results: There was a mean increase in excess weight loss from 20.4% to 34.1% without the need for band readjustment. 2 patients had intolerance to topiramate and were changed to fluoxetine 40 mg per day. Conclusion: Topiramate may be a useful adjuvant for patients with AGB and binge eating disorder.
Curtis's Botanical Magazine, 1996
Summary. Previously unpublished paintings of Brazilian orchids by Barbosa Rodrigues are to be res... more Summary. Previously unpublished paintings of Brazilian orchids by Barbosa Rodrigues are to be restored and published as Iconographie des Orchidées du Brésil.
Biocontrol Science and Technology, 2008
Dengue fever vectored by the mosquito Aedes aegypti is one of the most rapidly spreading insect-b... more Dengue fever vectored by the mosquito Aedes aegypti is one of the most rapidly spreading insect-borne diseases, stimulating the search for alternatives to current control methods. Screening assays using a range of Metarhizium anisopliae and Beauveria bassiana isolates were ...
Neotropical Biology and Conservation, 2010
Epiperipatus cratensis sp. nov. (Onychophora: Peripatidae) from northeastern Brazil Uma nova espé... more Epiperipatus cratensis sp. nov. (Onychophora: Peripatidae) from northeastern Brazil Uma nova espécie de Epiperipatus (Onychophora: Peripatidae) da região nordeste do Brasil Abstract This article aims to describe and illustrate Epiperipatus cratensis sp. nov. from Crato (coordinates 07°16'S,39°26'W), Ceará State, Brazil. Specimens of onychophorans were collected under stones and decomposing tree barks during the rainy season. E. cratensis differs from all of the species of the genus by having: (i) many pairs of legs, even though it is the second smallest species in size to the genus in Brazil; (ii) fewer rings of antennas than the other Brazilian species. Furthermore, E. cratensis is similar to E. tucupi, especially because females have 34 pairs of legs, and differs morphologically only by being shorter in size. In addition, this two species are located in different biomes: E. tucupi is endemic to the Amazon region, while E. cratensis is derived from Chapada do Araripe mountains, within Atlantic Forest biome of the Brejos de Altitude complex of northeastern Brazil.
Journal of Ethnobiology and Ethnomedicine, 2009
Background Animals have been used as a source of medicine in Brazil since ancient times, and have... more Background Animals have been used as a source of medicine in Brazil since ancient times, and have played a significant role in healing practices. Specifically in Northeast Brazil, zootherapy is a very common practice, and together with medicinal plants, it plays an important role as a therapeutic alternative. In the state of Ceara, no works have been carried out on rural communities with regard to use of zootherapeutics, even though the practice of zootherapy is common in this region. Therefore, the aim of this study was to analyze the use of medicinal animals in a rural community (Poco Dantas) in the municipality of Crato, Ceara, Brazil. Methods The field survey was carried out from October 2008 to January 2009 by conducting interviews using structured questionnaires with 72 people (33 men and 39 women), who provided information on animal species used as remedies, body parts used to prepare the remedies, and ailments for which the remedies were prescribed. We calculated the informant consensus factor (ICF) to determine the consensus over which species are effective for particular ailments, as well as the species use value (UV) to determine the extent of utilization of each species. Results A total of 29 species, distributed in 17 families were categorized as having some medicinal property. The taxa most represented were: mammals (9), insects (7), reptiles and birds (4). Progne chalybea, a species not previously recorded as being of medicinal use, was cited in the present work, where it is utilized in the treatment of alcoholism. The animals are used in the treatment of 34 diseases or symptoms, where sore throat, inflammations and cough are the ailments with the greatest number of citations. Conclusion The data show that zootherapy represents an important therapeutic alternative for the inhabitants of the community. New studies on medicinal fauna should be conducted with the aim of determining the exploitation level of the species utilized, promoting sustainable development of medicinal species that are eventually threatened, and preserving and disseminating the knowledge developed by traditional individuals of the community.
Brazilian Journal of Biology, 2006
Espécies de Porocephalus (Pentastomida) infectando Boa constrictor (Boidae) e Lachesis muta (Vipe... more Espécies de Porocephalus (Pentastomida) infectando Boa constrictor (Boidae) e Lachesis muta (Viperidae) na Região Nordeste do Brasil. O Brasil possui uma grande diversidade de cobras, mas há poucos trabalhos realizados sobre parasitismo destas por pentastomídeos. No intuito de investigar o parasitismo pulmonar por pentastomídeos em grandes cobras na região nordeste, foram examinados seis espécimes de Boa constrictor e duas de Lachesis muta pertencentes à coleção do Serpentário da Universidade Federal de Pernambuco -UFPE, todos coletadas em localidades de mata úmida (Mata Atlântica). Apenas um espécime de B. constrictor estava infectado por Porocephalus sp. (intensidade de infecção 5,0). Apenas um espécime de L. muta estava infectado por P. stilesi (intensidade de infecção 15,0).
Brazilian Journal of Biology, 2006
Cephalobaenidae constitutes one of the main pentastomid groups infecting the respiratory tract of... more Cephalobaenidae constitutes one of the main pentastomid groups infecting the respiratory tract of snakes. Six specimens of Liophis lineatus, a colubrid, were collected by active capture and pitfalls installed on the banks of the Batateiras river, close to its source, in the APA Área de Proteção Ambiental (a protected environmental area of the IBAMA Brazilian Institute for the Environment and Natural Resources), and in a remnant of the humid tropical forest FLONA Floresta Nacional do Araripe, both in the municipality of Crato, state of Ceará, Northeast Brazil. Out of the six specimens of L. lineatus examined, only one had its lung infected by the pentastomid Cephalobaena tetrapoda. This represents the first record of C. tetrapoda as a parasite of a snake in Northeast Brazil, as well as the first record of a colubrid, L. lineatus, as a new host for the pentastomid in Brazil.
Journal of Ethnopharmacology, 2010
Tupinambis merianae is one of the most frequently used animals in traditional medicine in Brazil ... more Tupinambis merianae is one of the most frequently used animals in traditional medicine in Brazil as its body fat has many different therapeutic indications as a folk remedy. The present study evaluated the topical anti-inflammatory activity of Tupinambis merianae fat in treating ear edema in an animal model.Oil (OTM) was extracted from body fat located in the ventral region of Tupinambis merianae using hexane as a solvent. Ear edema provoked by the application of croton oil (single and multiple application), arachidonic acid, phenol and capsaicin to Swiss mice was used to evaluate the potential anti-inflammatory value of the topical use of OTM. Topical applications of these irritants were made to the right ears of animals that were pre-treated with a acetone (control), dexamethasone, or OTM.Our results indicate that Tupinambis merianae fat demonstrates significant topical anti-inflammatory activity that reduces inflammation related to ear edema caused by croton oil (single and multiple application), arachidonic acid, phenol. While the inflammation caused by capsaicin, OTM did not significantly reduce the edema.This represents the first evidence of anti-inflammatory activity of Tupinambis merianae fat in in vivo models, confirming its usefulness in traditional medicine as a remedy for skin diseases (dermatitis). The fatty acids present in OTM most likely inhibit the response pathway of arachidonic acid and its metabolites, thus reducing the production of pro-inflammatory mediators.
BMC Complementary and Alternative Medicine, 2009
Background: Human communities consistently develop a detailed knowledge of the therapeutical and ... more Background: Human communities consistently develop a detailed knowledge of the therapeutical and medicinal properties of the local flora and fauna, and these folk remedies often substitute medicines produced by the pharmaceutical industry. Animals (and their derived products) are essential ingredients in the preparation of many traditional remedies. The present work prepared an inventory of the animals sold in public markets in the cities of Crato and Juazeiro do Norte, Ceará State, Brazil.
Journal of Ethnopharmacology, 2009
Tupinambis merianae is one of the animals that is most frequently used for medicinal purposes in ... more Tupinambis merianae is one of the animals that is most frequently used for medicinal purposes in Brazil as its body fat has many therapeutic indications in local folk medicine. This work presents the chemical compositions of the body fat of Tupinambis merianae and evaluates the antibacterial activity of the body fat as well as the ecological implications of its use in traditional medicine.Oil (OTM) was extracted from body fat located in the ventral region of Tupinambis merianae using hexane as a solvent. Fatty acids were determined indirectly using their corresponding methyl esters. The antibacterial activity of OTM was tested against standard as well as multi-resistant lines of Escherichia coli and Staphylococcus aureus, either alone or in combination with antibiotics and UV-A light.Body fat of Tupinambis merianae presents 57% and 43% of unsaturated and saturated fatty acids respectively. Our results indicated that OTM did not demonstrate relevant antibacterial activity against any of the lines of Escherichia coli or Staphylococcus aureus, nor when combined with antibiotics or with UV-A light.In light of these results, we recommend (i) development of management plans for a sustainable and rational use of Tupinambis merianae reducing the possible pressure on this species; and (ii) more studies be focused on the use of OTM and other natural products derived from animals that are used to treat other illnesses.
Natural Product Research, 2012
In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacteria... more In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacterial activity against multiresistant strains of Escherichia coli and Staphylococcus aureus. The antibacterial and modulatory activity of the extracts was assayed by microdilution. The light-enhanced antibacterial activity was assayed by light regimen. The growth of the bacteria tested was not inhibited by the extracts. The minimum inhibitory concentration (MIC) values ranged from 512 to ≥1024 µg · m L−1. However, the antibiotic activity of the aminoglycosides was synergistically enhanced when these extracts were associated in sub-inhibitory concentrations with the antibiotics. Both extracts showed activity against at two standard bacterial strains. Because of this, we suggest that the ethanol extracts of the stems and leaves of Costus cf. arabicus L. show potential antibacterial, light-induced and synergistic antibiotic activity. With such results, these extracts are proven to be a promising source of antibacterial and modulatory agents.
Natural Product Research, 2011
In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacteria... more In this study, the methanol extracts of of Costus cf. arabicus L. were evaluated for antibacterial activity against multiresistant strains of Escherichia coli and Staphylococcus aureus. The antibacterial and modulatory activity of the extracts was assayed by microdilution. The light-enhanced antibacterial activity was assayed by light regimen. The growth of the bacteria tested was not inhibited by the extracts. The minimum inhibitory concentration (MIC) values ranged from 512 to ≥1024 µg · m L−1. However, the antibiotic activity of the aminoglycosides was synergistically enhanced when these extracts were associated in sub-inhibitory concentrations with the antibiotics. Both extracts showed activity against at two standard bacterial strains. Because of this, we suggest that the ethanol extracts of the stems and leaves of Costus cf. arabicus L. show potential antibacterial, light-induced and synergistic antibiotic activity. With such results, these extracts are proven to be a promising source of antibacterial and modulatory agents.