SERAP BAŞ - Academia.edu (original) (raw)

Papers by SERAP BAŞ

Kardiologia Polska, Dec 11, 2023

Cardiology in The Young, May 17, 2023

Mixed total anomalous pulmonary venous connection is a rare CHD with a wide variation in pulmonar... more Mixed total anomalous pulmonary venous connection is a rare CHD with a wide variation in pulmonary venous anatomy and drainage. We present a ten-day-old newborn with a rare bizarre subtype of mixed total anomalous pulmonary venous connection.

Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, Sep 1, 2009

Objectives: We investigated whether coronary calcification detected by multislice computed tomogr... more Objectives: We investigated whether coronary calcification detected by multislice computed tomography (MSCT) was correlated with plasma osteopontin, serum fetuin-A, and visfatin levels. Study design: The study included 64 consecutive patients (51 males, 13 females; mean age 49.5+/-10.9 years; range 33 to 78 years) who underwent MSCT for suspected coronary artery disease. Coronary artery calcification (CAC) scores of the patients were calculated using the Agatston scoring method. Plasma osteopontin, serum fetuin-A, and visfatin levels were measured from fasting blood samples and correlations were sought with calcium scores. Results: Coronary calcification was detected in 32 patients (50%). The mean CAC score was 146.5+/-333.7 Agatston units (AU), indicating an intermediate risk for coronary artery disease. In 10 patients (15.6%), the CAC score exceeded 400 AU. The mean fetuin-A, visfatin, and osteopontin levels were 25.6+/-6.4 ng/ml, 19.7+/-47.2 ng/ml, and 20.4+/-16.1 ng/ml, respectively. Serum visfatin (r=0.15, p=0.37) and fetuin-A (r=0.17, p=0.22) were not correlated with the CAC score, whereas plasma osteopontin level showed a moderate correlation with the CAC score (r=0.35; p=0.008). In ROC analysis, the area under the curve for identification of CAC was greatest for osteopontin (0.741; p=0.004), followed by fetuin-A (0.574; p=0.31), and visfatin (0.580; p=0.27). The cut-off value was 18.45 ng/ml for osteopontin, with a sensitivity of 72% and specificity of 73%. Conclusion: Our results suggest that there might be an association between CAC and plasma osteopontin levels. Research should continue to find out a metabolic parameter that will strongly indicate coronary calcification.

International Journal of Cardiovascular Imaging, Sep 6, 2021

The purpose of this study is to evaluate the radiation dose, image quality, and diagnostic accura... more The purpose of this study is to evaluate the radiation dose, image quality, and diagnostic accuracy of prospective ECG-gated cardiac CT at 70 kV and adaptive statistical iterative reconstruction (ASIR), with a single source, 512 slice MDCT in the diagnosis of complex congenital heart disease in infants. We retrospectively evaluated 47 infants (ages 1 day to 353 days) with prospective ECG-gated cardiac CT that was performed on a single source 512 slice CT at low tube voltage (70 kV) using a wide detector aperture, adaptive statistical iterative reconstruction algorithm (ASIR), and specific reconstruction software reducing coronary motion artifacts (SnapShot Freeze). All cardiac images were obtained during the first pass of contrast material through the anatomic structures of interest and the targets for the center of the acquisition window were set 45% of the R-R interval during one cardiac cycle without sedation and breath-hold. The median effective dose measured in our study was 0.64 ± 0.16 mSv. The average subjective overall image quality score was 4.34 ± 0.31 (range 3–5). For the determination of objective image quality, Mean Noise (HU), SNR, and CNR values emerged as 20.8, 28.7(for pulmonary artery), and 27.1, respectively. Diagnostic accuracy was 100% for the main purposes for the main clinical indication. During cardiac CT examination, pathologies in addition to cardiac anomalies were found in 9/47 of cases (7 severe airway obstructions,1 posterior diaphragmatic hernia, 1 vertebral anomaly). Prospective ECG-gated cardiac CT scan at 70 kV and ASIR in infants with complex CHD provides low radiation dose (submillisievert) in a single heartbeat with a good objective and subjective image quality. It also provides important benefits in the diagnosis of additional pathology.

Transplantation Proceedings, 2011

Purpose. For many years there has been reluctance to use kidneys having multiple arteries of Ͻ2 m... more Purpose. For many years there has been reluctance to use kidneys having multiple arteries of Ͻ2 mm diameter, especially where they supply the lower pole. The usage of these kidneys has increased using microsurgical anastomosis techniques. We reviewed the anastomotic techniques among renal transplantations with multiple arteries. Materials and Methods. Between January 2008 and August 2010, we examined the perfusion of 605 live donor kidneys bearing multiple arteries at 1 week and after 3 months using Doppler ultrasonography and magnetic resonance imaging (MRI) angiography. In addition, we reviewed vascular and urinary complications. The diameters of the arteries were measured using multi-slice computerized tomographic (CT) angiography. Results. Multiple arteries were detected in 49 (8.1%) kidneys, including 14 from the right and 35 left: namely, 45 with double and 4 with 3 arteries. In 26 patients an end-to-side microsurgical anastomosis was performed using the accessory artery; 23 organs underwent other techniques. The average diameter of all arteries was 3.89 Ϯ 1.38 mm (thinnest, 1.2; widest, 8 mm). The average diameter of the main arteries was 5.12 Ϯ 1.16 mm (thinnest, 3; widest, 8 mm) and the accessory arteries 2.81 Ϯ 0.69 mm (thinnest, 1.2; widest, 3.8 mm). In patients with microsurgical techniques the average diameters of all arteries and accessory arteries were 3.7 Ϯ 1.6 mm and 2.6 Ϯ 0.69 mm, respectively. In those undergoing techniques other than microsurgery, the average diameters of all arteries and accessory arteries were 4.11 Ϯ 1.34 mm and 3.1 Ϯ 0.43 mm, respectively. The average diameters of the arteries in both groups were significantly different (P Ͻ .001). Kidney perfusion was intact upon ultrasonographic and MRI angiography of all patients. In 1 subject with a microsurgical technique used, anastomostic dehiscence with bleeding was observed after removal of the arterial clamps. Also in this group, 1 patient experienced a ureteral stricture beyond postoperative month one. Conclusion. Microsurgery is a reliable technique for kidneys with thin accessory renal arteries.

Indian Journal of Orthopaedics

In this article the name of author Aziz Çataltepe was incorrectly written as Aziz Çataltape. The ... more In this article the name of author Aziz Çataltepe was incorrectly written as Aziz Çataltape. The original article has been corrected. Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Kardiologia polska, 2010

We present a patient with abnormal origin of the right coronary artery from the left anterior des... more We present a patient with abnormal origin of the right coronary artery from the left anterior descending artery. The patient had chest pain probably related to myocardial ischemia. This anomaly is very rare and has only been reported in a few cases. The abnormal vessel had a rightward course following its take-off from the left anterior descending artery and remained anterior to the main pulmonary artery. There was no significant obstruction. The mechanism of myocardial ischemia remains unexplained.

International Journal of Cardiology, 2009

The coronary pulmonary fistulas are usually discovered incidentally during routine cardiac cathet... more The coronary pulmonary fistulas are usually discovered incidentally during routine cardiac catheterization after the development of atherosclerotic coronary artery disease. Here we present a 59-year-old man with anginal symptoms who was found to have two fistulas originating from the left coronary system and right coronary sinus and draining into the pulmonary trunk. We delineated the courses of the fistulas in detail using both of the imaging techniques of MDCT and conventional angiograhy.

International Journal of Cardiology, 2010

We aimed to report incidental noncoronary findings of coronary MSCT angiography and to evaluate t... more We aimed to report incidental noncoronary findings of coronary MSCT angiography and to evaluate the feasibility of scanning the entire thorax on Ca score imaging. Methods: 514 patients underwent cardiac MSCT. Instead of scanning just the heart, 124 of them were scanned extensively from the lung apex to the base in order to evaluate the entire thorax for additional findings. Furthermore, we calculated dose length product (DLP) in order to determine mean increase of radiation exposure resulting from lengthened scan field. Results: Coronary artery disease were established in 122 patients (24%) and 273 noncoronary findings were identified in 189 patients (37%). 37 pulmonary nodules (PN) ≥ 5 mm, 6 of which were over the level of pulmonary trunk, were detected. The mean age (62 ± 8 vs.49 ± 10, respectively; p b 0.0001) and the smoking rate (74% vs. 56%, respectively; p b 0.05) of the patients with PN were significantly higher than subjects without PN. All patients with PN over the level of pulmonary artery were smokers N 50 of age. On Ca score imaging, radiation exposure of widely scanned group was significantly higher than the others (221.3 ± 35.2 mGy cm vs.145.3 ± 11.7 mGy cm of DLP, respectively; p b 0.0001). Conclusion: Since MSCT data contain also information about the other structures in the thorax, the images should be evaluated by radiologist in addition to cardiologist. It seems reasonable to scan the entire thorax on Ca score imaging for smokers over 50 in order to detect pulmonary nodules having malignancy potential.

BMC Urology, 2014

Background Animal studies have shown that nicotine affects the peristalsis of the ureter. The aim... more Background Animal studies have shown that nicotine affects the peristalsis of the ureter. The aim of the study is to analyze the effect of smoking on spontaneous passage of distal ureteral stones. Methods 88 patients in whom distal ureteral stone below 10 mm diameter diagnosed with helical computerized tomography enhanced images were reviewed. Patients were grouped as either smokers (n:33) or non smokers (n:50). Follow-up for spontaneous passage of stones was limited with 4 weeks. Patients did not receive any additional medical treatment other than non-steroid anti inflamatory drugs only during painful renal colic episodes. Two groups were compared with the chi-square test in terms of passing the stone or not. Stone passage was confirmed with either the patient collecting the stone during urination or by helical CT. Results Smoking habits was present in 30(34%) patients and the frequency in both groups were similar (smokers: 23(76%) vs non-smokers: 46(79%)). Spontaneous passage of t...

Angiology, 2013

Acute mesenteric ischemia is a rare but serious complication of open heart surgery. Between Janua... more Acute mesenteric ischemia is a rare but serious complication of open heart surgery. Between January 2009 and January 2012, 1360 adult patients underwent open heart surgery with cardiopulmonary bypass at our institution; 29 patients presented gastrointestinal complications. Eight patients developed acute mesenteric ischemia and all of them died. Significant predictors of the complication were New York Heart Association functional class III/IV, history of extensive atherosclerosis and chronic renal failure, acute renal failure following surgery, low cardiac output, use of 2 or more vasoconstrictor drugs, prolonged mechanical ventilation, and multiorgan failure. Atherosclerosis is a multisystemic disease that affects several organs. Radiologic evaluation of mesenteric arterial system should be performed in high-risk patient populations. Perioperative percutaneous and open vascular procedures will reduce the risk of acute mesenteric ischemia that may develop after cardiac surgery and co...

Asian Cardiovascular and Thoracic Annals, 2012

A 62-year old woman presented with dizziness and a high degree of stenosis on left internal carot... more A 62-year old woman presented with dizziness and a high degree of stenosis on left internal carotid artery on Doppler ultrasound. Computed tomography angiography showed 90%-95% stenosis and coiling of the left internal carotid artery (Figure 1). Eversion carotid endarterectomy and a 2-cm shortening procedure were performed (Figures 2 and 3).

Journal of Neurosurgery: Pediatrics, 2005

UVENILE hyaline fibromatosis is a rare autosomal-recessive disease characterized by papulonodular... more UVENILE hyaline fibromatosis is a rare autosomal-recessive disease characterized by papulonodular skin lesions, gingival hyperplasia, joint contractures, and osteolytic lesions on long bones and the skull. 13 The disease maps to chromosome 4q21, and it has recently been reported that it is caused by mutations in the gene encoding CMG-2. 4,9,16 Since first described by Murray in 1873 as molluscum fibrosum, fewer than 60 cases have been published in the dermatological, orthopedic, and otorhinolaryngological literature (but not in neurosurgical literature). 2 Despite multiple osteolytic lesions of the skull with other common manifestations of the disease such as skin lesions, gingival hyperplasia, or joint involvement, no case exists in the literature of a patient presenting with a solitary calvarial osteolytic lesion. In this case report we describe a 4-year-old boy presenting with such a lesion, which on histopathological examination revealed findings typical of JHF; however, mutational analysis revealed that there were no mutations in the CMG-2 gene. Case Report Examination and Operation. This 4-year-old boy was admitted to the hospital because of a solitary painless swollen lesion that had gradually grown for 2 years on his right temporoparietal region. He was the only offspring of nonconsanguineous parents. On physical examination, an immobile, painless 3 ϫ 2-cm mass was evident. No other pathological characteristics were found on systemic examination or in routine biochemical investigations. A lytic lesion with a hyperostotic regular rim was seen on craniography (Fig. 1). Cranial CT scans revealed that the lesion involved the external tabula and the diploe, but the internal tabula remained intact (Fig. 2). The lesion was totally removed with the periosteum on it. The internal tabula was intact as seen on CT scans. Histological Findings. Histopathological examination of

The Spine Journal, 2007

BACKGROUND CONTEXT: Spinal extradural angiolipomas are rare benign tumors, and most of them are n... more BACKGROUND CONTEXT: Spinal extradural angiolipomas are rare benign tumors, and most of them are noninfiltrating tumors located in the extradural space. However, there are 17 cases with extradural infiltrating spinal angiolipomas extending into the vertebral bodies or posterior vertebral arches in literature. These 17 tumors are mostly located at the thoracic region, and anterior or in the anterolateral extradural space, and they generally infiltrate only one vertebra. Only two of them are located at the lumbar region, four are mainly located in the posterior extradural space, and three infiltrate more than one vertebra. PURPOSE: To present an exceptional case with infiltrating extradural spinal angiolipoma involving two lumbar segments and mainly located in the posterior extradural space. STUDY DESIGN: A case report. METHODS: A 41-year-old woman with infiltrating spinal angiolipoma was treated by incomplete surgical removal of the tumor. RESULTS: There were no complaints nor recurrence after 18 months follow-up. CONCLUSIONS: Outcome after surgery for spinal angiolipomas is very good overall even in the cases with infiltrating tumors. Although complete removal is certainly preferred, outcomes remained favorable despite incomplete resections.

Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē

Cardiology in the Young

Ventriculoarterial connection is one of the important points of the segmental approach to congeni... more Ventriculoarterial connection is one of the important points of the segmental approach to congenital cardiac malformations. Double outlet of both ventricles is a rare form where both great arterial roots override the interventricular septum. In this article, we aimed to draw attention to this very rare form of ventriculoarterial connection by presenting an infant case diagnosed using echocardiography, CT angiography, and 3-dimensional modelling.

Rheumatology, Mar 10, 2023