SERGIO VELASCO - Academia.edu (original) (raw)
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Papers by SERGIO VELASCO
FEMS Yeast Research, 2014
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FEMS Yeast Research, 2012
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Environmental Science & Technology, 2009
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Physical Review E, 2017
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Water Science & Technology, 2011
Here we present a metabolic network representing the central carbon metabolism as well as the syn... more Here we present a metabolic network representing the central carbon metabolism as well as the synthesis of polyhydroxyalcanohates and the polyphosphate accumulation mechanisms of the bacterium Candidatus Accumulibacter phosphatis, which was previously identified from metagenomic studies in enhanced biological phosphorous removal sludges. The reconstructed metabolic network, together with flux balance analysis can be used to provide new insights into controversial aspects of the metabolism of phosphate-accumulating organisms and is also a tool that can be used in to help enhanced biological phosphorous removal (EBPR) process design and operation.
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Scientific reports, 2013
The search for optimization principles in microbial metabolism, such as biomass or ATP yields or ... more The search for optimization principles in microbial metabolism, such as biomass or ATP yields or growth rate optimization, has attracted substantial research efforts in the recent years. Here we use the results of C13 labeling experiments together with genome scale metabolic networks of S cerevisiae and E coli in order to assess if there are relationships between systemic variables that are present in both organisms. Strong correlations between the total flux per unit of substrate and the ATP turnover rate per unit of substrate and between the growth rate divided by the total flux and the total flux per unit of substrate were observed for both organisms. We also observed that the common assumption of biomass yield optimization is not consistent with the experiments.
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Microbial Biotechnology, 2011
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FEMS Yeast Research, 2014
Bookmarks Related papers MentionsView impact
FEMS Yeast Research, 2012
Bookmarks Related papers MentionsView impact
Environmental Science & Technology, 2009
Bookmarks Related papers MentionsView impact
Physical Review E, 2017
Bookmarks Related papers MentionsView impact
Water Science & Technology, 2011
Here we present a metabolic network representing the central carbon metabolism as well as the syn... more Here we present a metabolic network representing the central carbon metabolism as well as the synthesis of polyhydroxyalcanohates and the polyphosphate accumulation mechanisms of the bacterium Candidatus Accumulibacter phosphatis, which was previously identified from metagenomic studies in enhanced biological phosphorous removal sludges. The reconstructed metabolic network, together with flux balance analysis can be used to provide new insights into controversial aspects of the metabolism of phosphate-accumulating organisms and is also a tool that can be used in to help enhanced biological phosphorous removal (EBPR) process design and operation.
Bookmarks Related papers MentionsView impact
Scientific reports, 2013
The search for optimization principles in microbial metabolism, such as biomass or ATP yields or ... more The search for optimization principles in microbial metabolism, such as biomass or ATP yields or growth rate optimization, has attracted substantial research efforts in the recent years. Here we use the results of C13 labeling experiments together with genome scale metabolic networks of S cerevisiae and E coli in order to assess if there are relationships between systemic variables that are present in both organisms. Strong correlations between the total flux per unit of substrate and the ATP turnover rate per unit of substrate and between the growth rate divided by the total flux and the total flux per unit of substrate were observed for both organisms. We also observed that the common assumption of biomass yield optimization is not consistent with the experiments.
Bookmarks Related papers MentionsView impact
Microbial Biotechnology, 2011
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