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Papers by S. Garfinkel

Research paper thumbnail of Fear from the Heart: Sensitivity to Fear Stimuli Depends on Individual Heartbeats

Journal of Neuroscience, 2014

Cognitions and emotions can be influenced by bodily physiology. Here, we investigated whether the... more Cognitions and emotions can be influenced by bodily physiology. Here, we investigated whether the processing of brief fear stimuli is selectively gated by their timing in relation to individual heartbeats. Emotional and neutral faces were presented to human volunteers at cardiac systole, when ejection of blood from the heart causes arterial baroreceptors to signal centrally the strength and timing of each heartbeat, and at diastole, the period between heartbeats when baroreceptors are quiescent. Participants performed behavioral and neuroimaging tasks to determine whether these interoceptive signals influence the detection of emotional stimuli at the threshold of conscious awareness and alter judgments of emotionality of fearful and neutral faces. Our results show that fearful faces were detected more easily and were rated as more intense at systole than at diastole. Correspondingly, amygdala responses were greater to fearful faces presented at systole relative to diastole. These novel findings highlight a major channel by which short-term interoceptive fluctuations enhance perceptual and evaluative processes specifically related to the processing of fear and threat and counter the view that baroreceptor afferent signaling is always inhibitory to sensory perception.

Research paper thumbnail of Past, Future, Good, Bad: The Neural Networks Supporting Content in Self-Generated Thought

Research paper thumbnail of The Impact of Affective Symptoms on Brain Networks When Thinking About the Past and Future

Research paper thumbnail of Effect of Parasympathetic Stimulation on Brain Activity During Appraisal of Fearful Expressions

Neuropsychopharmacology, 2015

Mental processes influence bodily physiology, which in turn feeds back to influence thoughts and ... more Mental processes influence bodily physiology, which in turn feeds back to influence thoughts and feelings. Afferent cardiovascular signals from arterial baroreceptors in the carotid sinuses are processed within the brain and contribute to this two-way communication with the body.

Research paper thumbnail of Stress and the expression of dissociative symptoms in neurodevelopmental and neuropsychiatric disorders

International Journal of Psychophysiology, 2012

Research paper thumbnail of Interaction between cognition, emotion, and the autonomic nervous system

Handbook of Clinical Neurology, 2013

Research paper thumbnail of Fear from the Heart: Sensitivity to Fear Stimuli Depends on Individual Heartbeats

Journal of Neuroscience, 2014

Cognitions and emotions can be influenced by bodily physiology. Here, we investigated whether the... more Cognitions and emotions can be influenced by bodily physiology. Here, we investigated whether the processing of brief fear stimuli is selectively gated by their timing in relation to individual heartbeats. Emotional and neutral faces were presented to human volunteers at cardiac systole, when ejection of blood from the heart causes arterial baroreceptors to signal centrally the strength and timing of each heartbeat, and at diastole, the period between heartbeats when baroreceptors are quiescent. Participants performed behavioral and neuroimaging tasks to determine whether these interoceptive signals influence the detection of emotional stimuli at the threshold of conscious awareness and alter judgments of emotionality of fearful and neutral faces. Our results show that fearful faces were detected more easily and were rated as more intense at systole than at diastole. Correspondingly, amygdala responses were greater to fearful faces presented at systole relative to diastole. These novel findings highlight a major channel by which short-term interoceptive fluctuations enhance perceptual and evaluative processes specifically related to the processing of fear and threat and counter the view that baroreceptor afferent signaling is always inhibitory to sensory perception.

Research paper thumbnail of Past, Future, Good, Bad: The Neural Networks Supporting Content in Self-Generated Thought

Research paper thumbnail of The Impact of Affective Symptoms on Brain Networks When Thinking About the Past and Future

Research paper thumbnail of Effect of Parasympathetic Stimulation on Brain Activity During Appraisal of Fearful Expressions

Neuropsychopharmacology, 2015

Mental processes influence bodily physiology, which in turn feeds back to influence thoughts and ... more Mental processes influence bodily physiology, which in turn feeds back to influence thoughts and feelings. Afferent cardiovascular signals from arterial baroreceptors in the carotid sinuses are processed within the brain and contribute to this two-way communication with the body.

Research paper thumbnail of Stress and the expression of dissociative symptoms in neurodevelopmental and neuropsychiatric disorders

International Journal of Psychophysiology, 2012

Research paper thumbnail of Interaction between cognition, emotion, and the autonomic nervous system

Handbook of Clinical Neurology, 2013

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