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Research paper thumbnail of Nutritional Intake of Sport Undergraduates in Sri Lanka

BACKGROUND Nutritional intake plays an important role in determining energy availability which is... more BACKGROUND Nutritional intake plays an important role in determining energy availability which is vital to health, wellbeing, and sports performance in an active population. This research assessed the sports undergraduates' nutritional intake compared to the Dietary Guidelines for Americans and nutrition goals provided by WHO. METHODS A total of one hundred and one (n = 101) sports undergraduates aged between 20 to 23 years were recruited and the nutrient intake was assessed by the three-day food diary method and quantified the macro and micronutrients by the food composition database. RESULTS Though most undergraduates were able to meet the dietary requirements in carbohydrates, they were deficient in their protein intake and excess in fats intake. Further, both male and female students were deficient in their daily energy intake (1723kcal, 1607 kcal) and dietary fiber intake (8 g, 11 g). The fat intake as saturated fat was met by all students’ intake a 20% of males and 21% of ...

Research paper thumbnail of A Study on the Relationship between Competitive State Anxiety and Shooting Accuracy of School Level Netball Shooters in Gampaha District, Sri Lanka

The IUP Journal of Soft Skills, Mar 1, 2015

The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) ... more The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) and shooting accuracy of Gampaha district school level Netball shooters. CSA is temporary, ever-changing emotional state of subjective, consciously perceived feelings of apprehension and tension, associated with activation of autonomic nervous system, and made up of cognitive and somatic anxiety. Thirty shooters (N = 30) at the age of 14 to 18 from Gampaha district school level netball teams were randomly selected from the Zonal Netball Tournaments draws. Competitive State Anxiety Inventory-II was used to collect data. All individuals were asked to complete questionnaire, 30 minutes prior to the competition. Each individuals shooting accuracy was measured by successful attempts out of total attempts in three matches. The study revealed that ( 0.393), ( 0.193), (–0.183) correlations in self-confidence, somatic anxiety and cognitive anxiety with the shooting accuracy respectively.

Research paper thumbnail of A Study on the Relationship between Competitive State Anxiety and Shooting Accuracy of School Level Netball Shooters in Gampaha District, Sri Lanka

The IUP Journal of Soft Skills, 2015

The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) ... more The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) and shooting accuracy of Gampaha district school level Netball shooters. CSA is temporary, ever-changing emotional state of subjective, consciously perceived feelings of apprehension and tension, associated with activation of autonomic nervous system, and made up of cognitive and somatic anxiety. Thirty shooters (N = 30) at the age of 14 to 18 from Gampaha district school level netball teams were randomly selected from the Zonal Netball Tournaments draws. Competitive State Anxiety Inventory-II was used to collect data. All individuals were asked to complete questionnaire, 30 minutes prior to the competition. Each individuals shooting accuracy was measured by successful attempts out of total attempts in three matches. The study revealed that ( 0.393), ( 0.193), (–0.183) correlations in self-confidence, somatic anxiety and cognitive anxiety with the shooting accuracy respectively.

Research paper thumbnail of Ultrasonically assisted preparation of poly(acrylic acid)/calcium phosphate hybrid nanogels as pH-responsive drug carriers

Materials science & engineering. C, Materials for biological applications, 2017

Biocompatible, biodegradable and stimuli-responsive nanomaterials can be used as drug carriers an... more Biocompatible, biodegradable and stimuli-responsive nanomaterials can be used as drug carriers and to achieve controlled drug delivery, which is crucial for treating tumors and lowering drug side effects. Calcium phosphate (CaP) nanoparticles and poly(acrylic acid) (PAA) hydrogels can be used as biocompatible and pH-responsive drug carriers. In this study, based on the ultrasound effect, PAA/CaP hybrid nanogels (approximately 100nm, PDI<0.2) are obtained via the cross-linking of CaP nanoparticles and PAA molecules between the Ca(2+) ions and -COOH groups. The PAA/CaP hybrid nanogels show good stability in biological media as well as no hemolysis and no cytotoxicity to L02 cells. Moreover, the PAA/CaP hybrid nanogels display an enhanced loading capacity (approximately 32%) for doxorubicin hydrochloride (DOX) compared to pure CaP nanoparticles (approximately 7.5%) and a pH-controlled drug release due to their dissolution in acidic environment. DOX can be delivered into cancer cells...

Research paper thumbnail of Luminescence Enhanced Eu3+/Gd3+ Co-Doped Hydroxyapatite Nanocrystals as Imaging Agents In Vitro and In Vivo

ACS applied materials & interfaces, Apr 4, 2016

Biocompatible, biodegradable and luminescent nano material can be used as an alternative bioimagi... more Biocompatible, biodegradable and luminescent nano material can be used as an alternative bioimaging agent for early cancer diagnosis, which is crucial to achieve successful treatment. Hydroxyapatite (HAP) nanocyrstals have good biocompatibility and biodegradability, and can be used as an excellent host for luminescent rare earth elements. In this study, based on the energy transfer from Gd3+ to Eu3+, the luminescence enhanced imaging agent of Eu/Gd co-doping HAP (HAP:Eu/Gd) nanocrystals are obtained via co-precipitation with plate-like shape and no change in crystal phase composition. The luminescence can be much elevated (up to about 120%) with nonlinearly increase versus Gd doping content, which is due to the energy transfer (6PJ of Gd3+→5HJ of Eu3+) under 273 nm and the possible combination effect of the cooperative upconversion and the successive energy transfer under 394 nm respectively. Results demonstrate that the biocompatible HAP:Eu/Gd nanocrystals can successfully perform ...

Research paper thumbnail of Quantitative Detection Method of Hydroxyapatite Nanoparticles Based on Eu3+ Fluorescent Labeling in Vitro and in Vivo

ACS Applied Materials & Interfaces, 2015

One major challenge for application of hydroxyapatite nanoparticles (nHAP) in nanomedicine is the... more One major challenge for application of hydroxyapatite nanoparticles (nHAP) in nanomedicine is the quantitative detection method. Herein, we exploited one quantitative detection method for nHAP based on the Eu(3+) fluorescent labeling via a simple chemical coprecipitation method. The trace amount of nHAP in cells and tissues can be quantitatively detected on the basis of the fluorescent quantitative determination of Eu(3+) ions in nHAP crystal lattice. The lowest concentration of Eu(3+) ions that can be quantitatively detected is 0.5 nM using DELFIA enhancement solution. This methodology can be broadly applicable for studying the tissue distribution and metabolization of nHAP in vivo.

Research paper thumbnail of Nutritional intake of sport undergraduates in Sabaragamuwa University of Sri Lanka

BMC Nutrition

Background Nutritional intake plays an important role in determining energy availability which is... more Background Nutritional intake plays an important role in determining energy availability which is vital to health, wellbeing, and sports performance in an active population. This research assessed the sports undergraduates' nutritional intake compared to the Dietary Guidelines for Americans and nutrition goals provided by WHO. Methods This study is a quantitative, cross-sectional descriptive study. One hundred and one (n = 101) sports undergraduates aged between 20 to 23 years were recruited and the nutrient intake was assessed using the three-day food diary method and quantified the macro and micronutrients by the food composition database. One sample t-test was performed to compare the mean nutrient intakes with the lowest recommendation values. Results Though most undergraduates were able to meet the dietary requirements in carbohydrates, they were deficient in their protein intake and exceeded in fats intake. Further, both male and female students were deficient in their dai...

Research paper thumbnail of Rare Earth Doped Apatite Nanomaterials for Biological Application

Journal of Nanomaterials, 2015

In most biological analyses, a sensitive detection technique is primarily dependent on the fluore... more In most biological analyses, a sensitive detection technique is primarily dependent on the fluorescence labeling agent. New generation of fluorophores called rare earth doped apatite nanoparticle (REAnp) has the ability to emit near infrared radiations which are of low absorptivity by tissue chromophores and especially suitable for biological system imaging. Moreover, bioapatite is demonstrated to be an excellent candidate for biomedical applications because of its biocompatibility, biodegradability, and bioactivity. During recent years a lot of efforts have been made for achievement of REAnp for medical diagnostics and targeted therapeutics applications. In this review, we discuss the significance of REAnps in biological systems, different root of synthesis, and biological applications. Also we discuss the future studies for the effective biological applications of REAnps.

Research paper thumbnail of Nutritional Intake of Sport Undergraduates in Sri Lanka

BACKGROUND Nutritional intake plays an important role in determining energy availability which is... more BACKGROUND Nutritional intake plays an important role in determining energy availability which is vital to health, wellbeing, and sports performance in an active population. This research assessed the sports undergraduates' nutritional intake compared to the Dietary Guidelines for Americans and nutrition goals provided by WHO. METHODS A total of one hundred and one (n = 101) sports undergraduates aged between 20 to 23 years were recruited and the nutrient intake was assessed by the three-day food diary method and quantified the macro and micronutrients by the food composition database. RESULTS Though most undergraduates were able to meet the dietary requirements in carbohydrates, they were deficient in their protein intake and excess in fats intake. Further, both male and female students were deficient in their daily energy intake (1723kcal, 1607 kcal) and dietary fiber intake (8 g, 11 g). The fat intake as saturated fat was met by all students’ intake a 20% of males and 21% of ...

Research paper thumbnail of A Study on the Relationship between Competitive State Anxiety and Shooting Accuracy of School Level Netball Shooters in Gampaha District, Sri Lanka

The IUP Journal of Soft Skills, Mar 1, 2015

The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) ... more The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) and shooting accuracy of Gampaha district school level Netball shooters. CSA is temporary, ever-changing emotional state of subjective, consciously perceived feelings of apprehension and tension, associated with activation of autonomic nervous system, and made up of cognitive and somatic anxiety. Thirty shooters (N = 30) at the age of 14 to 18 from Gampaha district school level netball teams were randomly selected from the Zonal Netball Tournaments draws. Competitive State Anxiety Inventory-II was used to collect data. All individuals were asked to complete questionnaire, 30 minutes prior to the competition. Each individuals shooting accuracy was measured by successful attempts out of total attempts in three matches. The study revealed that ( 0.393), ( 0.193), (–0.183) correlations in self-confidence, somatic anxiety and cognitive anxiety with the shooting accuracy respectively.

Research paper thumbnail of A Study on the Relationship between Competitive State Anxiety and Shooting Accuracy of School Level Netball Shooters in Gampaha District, Sri Lanka

The IUP Journal of Soft Skills, 2015

The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) ... more The aim of this study is to investigate the relationship between Competitive State Anxiety (CSA) and shooting accuracy of Gampaha district school level Netball shooters. CSA is temporary, ever-changing emotional state of subjective, consciously perceived feelings of apprehension and tension, associated with activation of autonomic nervous system, and made up of cognitive and somatic anxiety. Thirty shooters (N = 30) at the age of 14 to 18 from Gampaha district school level netball teams were randomly selected from the Zonal Netball Tournaments draws. Competitive State Anxiety Inventory-II was used to collect data. All individuals were asked to complete questionnaire, 30 minutes prior to the competition. Each individuals shooting accuracy was measured by successful attempts out of total attempts in three matches. The study revealed that ( 0.393), ( 0.193), (–0.183) correlations in self-confidence, somatic anxiety and cognitive anxiety with the shooting accuracy respectively.

Research paper thumbnail of Ultrasonically assisted preparation of poly(acrylic acid)/calcium phosphate hybrid nanogels as pH-responsive drug carriers

Materials science & engineering. C, Materials for biological applications, 2017

Biocompatible, biodegradable and stimuli-responsive nanomaterials can be used as drug carriers an... more Biocompatible, biodegradable and stimuli-responsive nanomaterials can be used as drug carriers and to achieve controlled drug delivery, which is crucial for treating tumors and lowering drug side effects. Calcium phosphate (CaP) nanoparticles and poly(acrylic acid) (PAA) hydrogels can be used as biocompatible and pH-responsive drug carriers. In this study, based on the ultrasound effect, PAA/CaP hybrid nanogels (approximately 100nm, PDI<0.2) are obtained via the cross-linking of CaP nanoparticles and PAA molecules between the Ca(2+) ions and -COOH groups. The PAA/CaP hybrid nanogels show good stability in biological media as well as no hemolysis and no cytotoxicity to L02 cells. Moreover, the PAA/CaP hybrid nanogels display an enhanced loading capacity (approximately 32%) for doxorubicin hydrochloride (DOX) compared to pure CaP nanoparticles (approximately 7.5%) and a pH-controlled drug release due to their dissolution in acidic environment. DOX can be delivered into cancer cells...

Research paper thumbnail of Luminescence Enhanced Eu3+/Gd3+ Co-Doped Hydroxyapatite Nanocrystals as Imaging Agents In Vitro and In Vivo

ACS applied materials & interfaces, Apr 4, 2016

Biocompatible, biodegradable and luminescent nano material can be used as an alternative bioimagi... more Biocompatible, biodegradable and luminescent nano material can be used as an alternative bioimaging agent for early cancer diagnosis, which is crucial to achieve successful treatment. Hydroxyapatite (HAP) nanocyrstals have good biocompatibility and biodegradability, and can be used as an excellent host for luminescent rare earth elements. In this study, based on the energy transfer from Gd3+ to Eu3+, the luminescence enhanced imaging agent of Eu/Gd co-doping HAP (HAP:Eu/Gd) nanocrystals are obtained via co-precipitation with plate-like shape and no change in crystal phase composition. The luminescence can be much elevated (up to about 120%) with nonlinearly increase versus Gd doping content, which is due to the energy transfer (6PJ of Gd3+→5HJ of Eu3+) under 273 nm and the possible combination effect of the cooperative upconversion and the successive energy transfer under 394 nm respectively. Results demonstrate that the biocompatible HAP:Eu/Gd nanocrystals can successfully perform ...

Research paper thumbnail of Quantitative Detection Method of Hydroxyapatite Nanoparticles Based on Eu3+ Fluorescent Labeling in Vitro and in Vivo

ACS Applied Materials & Interfaces, 2015

One major challenge for application of hydroxyapatite nanoparticles (nHAP) in nanomedicine is the... more One major challenge for application of hydroxyapatite nanoparticles (nHAP) in nanomedicine is the quantitative detection method. Herein, we exploited one quantitative detection method for nHAP based on the Eu(3+) fluorescent labeling via a simple chemical coprecipitation method. The trace amount of nHAP in cells and tissues can be quantitatively detected on the basis of the fluorescent quantitative determination of Eu(3+) ions in nHAP crystal lattice. The lowest concentration of Eu(3+) ions that can be quantitatively detected is 0.5 nM using DELFIA enhancement solution. This methodology can be broadly applicable for studying the tissue distribution and metabolization of nHAP in vivo.

Research paper thumbnail of Nutritional intake of sport undergraduates in Sabaragamuwa University of Sri Lanka

BMC Nutrition

Background Nutritional intake plays an important role in determining energy availability which is... more Background Nutritional intake plays an important role in determining energy availability which is vital to health, wellbeing, and sports performance in an active population. This research assessed the sports undergraduates' nutritional intake compared to the Dietary Guidelines for Americans and nutrition goals provided by WHO. Methods This study is a quantitative, cross-sectional descriptive study. One hundred and one (n = 101) sports undergraduates aged between 20 to 23 years were recruited and the nutrient intake was assessed using the three-day food diary method and quantified the macro and micronutrients by the food composition database. One sample t-test was performed to compare the mean nutrient intakes with the lowest recommendation values. Results Though most undergraduates were able to meet the dietary requirements in carbohydrates, they were deficient in their protein intake and exceeded in fats intake. Further, both male and female students were deficient in their dai...

Research paper thumbnail of Rare Earth Doped Apatite Nanomaterials for Biological Application

Journal of Nanomaterials, 2015

In most biological analyses, a sensitive detection technique is primarily dependent on the fluore... more In most biological analyses, a sensitive detection technique is primarily dependent on the fluorescence labeling agent. New generation of fluorophores called rare earth doped apatite nanoparticle (REAnp) has the ability to emit near infrared radiations which are of low absorptivity by tissue chromophores and especially suitable for biological system imaging. Moreover, bioapatite is demonstrated to be an excellent candidate for biomedical applications because of its biocompatibility, biodegradability, and bioactivity. During recent years a lot of efforts have been made for achievement of REAnp for medical diagnostics and targeted therapeutics applications. In this review, we discuss the significance of REAnps in biological systems, different root of synthesis, and biological applications. Also we discuss the future studies for the effective biological applications of REAnps.