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Papers by Sonia Mahey

Research paper thumbnail of A critical review on toxicity of cobalt and its bioremediation strategies

SN Applied Sciences

Accumulation of heavy metals especially cobalt (Co) in agricultural fields and water bodies due t... more Accumulation of heavy metals especially cobalt (Co) in agricultural fields and water bodies due to natural as well as anthropogenic factors is major concern. Although it is an important constituent of vitamin B 12 , yet its higher exposure produces significant ramifications in crop plants. It affects biomass and concomitantly reduces crop yield that in turn causes substantial financial loss to farmers. To counter this heavy metal toxicity, the plants have devised mechanisms either to detoxify or accumulate the contaminants. Further, there are various bioremediation strategies that can be used to get rid of Co from the given medium. Phytostabilisation, phytoextraction, rhizofiltration are some of the techniques used worldwide to reduce cobalt in the fields. This review emphasis upon the uptake, transportation, accumulation of cobalt in plants and discusses the remedial strategies available presently to effectively remove it from mediums like soil and water bodies.

Research paper thumbnail of Appraisal of tissue compartmentalized metal(loid) uptake by rice

Arabian Journal of Geosciences

Research paper thumbnail of Antagonistic effects of EDTA against biochemical toxicity induced by Cr(VI) in Hordeum vulgare L. seedlings

Physiology and Molecular Biology of Plants

Research paper thumbnail of Post-infectional changes associated with the progression of leaf spot disease in Calotropis procera Aiton

Physiological and Molecular Plant Pathology

Research paper thumbnail of Polyphenols From Cutch Tree ( Acacia catechu Willd.): Normalize In Vitro Oxidative Stress and Exerts Antiproliferative Activity

Brazilian Archives of Biology and Technology

Oxidative stress, being the main cause of most of the human diseases, has always been the highlig... more Oxidative stress, being the main cause of most of the human diseases, has always been the highlight of research worldwide. This stress can be overcome by administration of natural polyphenols. The Acacia catechu Willd. has many refrences available in Ayurveda as important disease curative plant. Its leaves are investigated for ameliorating oxidative stress in present work. Leaves of A. catechu were extracted with 80% methanol to get methanol extract (AME). It was assessed for antioxidant activity using DPPH, ABTS, CUPRAC, ferric ion reducing, superoxide scavenging and peroxyl radical scavenging assays. DNA protective activity was also investigated using plasmid nicking assay. Further, antiproliferative activity was determined using MTT assay in various human cancer cell lines. The quantification of polyphenols was done by UHPLC analysis. Results confirmed that polyphenols of A. catechu were successful in normalizing oxidative stress. AME was found to be most effective in scavenging ABTS radicals while least effective in scavenging ferric ions. UHPLC analysis showed abundance of ellagic acid, rutin and quercetin in AME. Further, AME showed maximum antiproliferative activity against Hep G2 cancer cells. It is concluded that the polyphenols from A. catechu effectively remediates oxidative stress and hence can be used in curing numerous dreadful diseases.

Research paper thumbnail of Maleic acid and EDTA mediated extenuation of Co(II) stress in Hordeum vulgare seedlings

Biotechnology Research and Innovation

Research paper thumbnail of Insights into biological properties of less explored bark of industrially important Acacia catechu Willd

Industrial Crops and Products

Research paper thumbnail of Effect of cobalt(II) chloride hexahydrate on some human cancer cell lines

The d-block elements confined to 3-12 groups of periodic table represent transition metals. They ... more The d-block elements confined to 3-12 groups of periodic table represent transition metals. They along with their complexes have found use in drug development since last decade (Gianferrara et al. 2009; Li et al. 2015). Their ability to exist in a number of oxidation states and reacting with other oppositely charged species has been exploited in medicinal chemistry. Some of the transition metals have been reported to possess antimicrobial, antifungal, antidiabetic and anticancer properties (Singh 2014). Different metal complexes viz., Ru(III), Co(II), Cu(II) nitrate, Pd(II) chloride, and coordination complexes of Pt(II), As, Sb, Bi, V, Fe, Rh, Ti and Ga have been investigated for their anticancer activities by various workers (

Research paper thumbnail of A critical review on toxicity of cobalt and its bioremediation strategies

SN Applied Sciences

Accumulation of heavy metals especially cobalt (Co) in agricultural fields and water bodies due t... more Accumulation of heavy metals especially cobalt (Co) in agricultural fields and water bodies due to natural as well as anthropogenic factors is major concern. Although it is an important constituent of vitamin B 12 , yet its higher exposure produces significant ramifications in crop plants. It affects biomass and concomitantly reduces crop yield that in turn causes substantial financial loss to farmers. To counter this heavy metal toxicity, the plants have devised mechanisms either to detoxify or accumulate the contaminants. Further, there are various bioremediation strategies that can be used to get rid of Co from the given medium. Phytostabilisation, phytoextraction, rhizofiltration are some of the techniques used worldwide to reduce cobalt in the fields. This review emphasis upon the uptake, transportation, accumulation of cobalt in plants and discusses the remedial strategies available presently to effectively remove it from mediums like soil and water bodies.

Research paper thumbnail of Appraisal of tissue compartmentalized metal(loid) uptake by rice

Arabian Journal of Geosciences

Research paper thumbnail of Antagonistic effects of EDTA against biochemical toxicity induced by Cr(VI) in Hordeum vulgare L. seedlings

Physiology and Molecular Biology of Plants

Research paper thumbnail of Post-infectional changes associated with the progression of leaf spot disease in Calotropis procera Aiton

Physiological and Molecular Plant Pathology

Research paper thumbnail of Polyphenols From Cutch Tree ( Acacia catechu Willd.): Normalize In Vitro Oxidative Stress and Exerts Antiproliferative Activity

Brazilian Archives of Biology and Technology

Oxidative stress, being the main cause of most of the human diseases, has always been the highlig... more Oxidative stress, being the main cause of most of the human diseases, has always been the highlight of research worldwide. This stress can be overcome by administration of natural polyphenols. The Acacia catechu Willd. has many refrences available in Ayurveda as important disease curative plant. Its leaves are investigated for ameliorating oxidative stress in present work. Leaves of A. catechu were extracted with 80% methanol to get methanol extract (AME). It was assessed for antioxidant activity using DPPH, ABTS, CUPRAC, ferric ion reducing, superoxide scavenging and peroxyl radical scavenging assays. DNA protective activity was also investigated using plasmid nicking assay. Further, antiproliferative activity was determined using MTT assay in various human cancer cell lines. The quantification of polyphenols was done by UHPLC analysis. Results confirmed that polyphenols of A. catechu were successful in normalizing oxidative stress. AME was found to be most effective in scavenging ABTS radicals while least effective in scavenging ferric ions. UHPLC analysis showed abundance of ellagic acid, rutin and quercetin in AME. Further, AME showed maximum antiproliferative activity against Hep G2 cancer cells. It is concluded that the polyphenols from A. catechu effectively remediates oxidative stress and hence can be used in curing numerous dreadful diseases.

Research paper thumbnail of Maleic acid and EDTA mediated extenuation of Co(II) stress in Hordeum vulgare seedlings

Biotechnology Research and Innovation

Research paper thumbnail of Insights into biological properties of less explored bark of industrially important Acacia catechu Willd

Industrial Crops and Products

Research paper thumbnail of Effect of cobalt(II) chloride hexahydrate on some human cancer cell lines

The d-block elements confined to 3-12 groups of periodic table represent transition metals. They ... more The d-block elements confined to 3-12 groups of periodic table represent transition metals. They along with their complexes have found use in drug development since last decade (Gianferrara et al. 2009; Li et al. 2015). Their ability to exist in a number of oxidation states and reacting with other oppositely charged species has been exploited in medicinal chemistry. Some of the transition metals have been reported to possess antimicrobial, antifungal, antidiabetic and anticancer properties (Singh 2014). Different metal complexes viz., Ru(III), Co(II), Cu(II) nitrate, Pd(II) chloride, and coordination complexes of Pt(II), As, Sb, Bi, V, Fe, Rh, Ti and Ga have been investigated for their anticancer activities by various workers (

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