Sabeela Noor - Academia.edu (original) (raw)

Papers by Sabeela Noor

Journal of Bahria University Medical and Dental College, 2021

Objective: To determine differences in eating practices, perceptions, and perceived barriers amon... more Objective: To determine differences in eating practices, perceptions, and perceived barriers among intermediate students of government and private sectors in Karachi. Study design and setting: A cross-sectional study was conducted in six intermediate colleges of Karachi from October to December 2018. Methodology: Total N=390 students aged 16-24 years were selected via non-probability convenience sampling. The study team developed a questionnaire to assess the dietary habits and barriers among the students. Results: Mean BMI of government college students was 20.41 ± 4.15 kg/m2 while that of private college students was 22.25 ± 5.43 kg/m2. The proportion of underweight participants was higher (36.8%) in government college students, and overweight students being higher in private (23.8%). Similar responses were recorded for daily meals and weekly fastfood and fruit consumption. Skipping meals was found out to be a common practice among students. Breakfast was most commonly skipped mea...

Background: Type 2 diabetes mellitus is becoming one of the major health problems worldwide. Espe... more Background: Type 2 diabetes mellitus is becoming one of the major health problems worldwide. Especially in South East Asia, type 2 diabetes has gained critical significance. As pre-diabetes prevalence is increasing worldwide, it has become an important concern to prevent diabetes at an early stage. Trace elements have been gaining attention in improving the glucometabolic conditions like pre-diabetes and diabetes. Zinc and copper are the major trace elements present in the human body and they play a significant role in the pathogenesis of diabetes mellitus and pre-diabetes. Objectives: The purpose of this study was to compare serum zinc and copper levels in type 2 diabetes and pre-diabetes. Methods: This study was conducted in department of Biochemistry BMSI, JPMC Karachi. Total 90 subjects were taken out of which 30 were type 2 diabetics, 30 were pre-diabetics and 30 were normal healthy individuals. Serum fasting glucose was measured by glucose oxidase method. Serum zinc and copper...

Objective: To estimate the levels of myeloperoxidase in various stages of chronic kidney disease,... more Objective: To estimate the levels of myeloperoxidase in various stages of chronic kidney disease, and to correlate them with an inflammatory marker and lipid profile.

JPMA. The Journal of the Pakistan Medical Association, 2017

OBJECTIVE To assess the ratio of soluble transferrin receptor to ferritin in different stages of ... more OBJECTIVE To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease. METHODS This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre, Karachi, from January to September 2014, and comprised chronic kidney disease patients and healthy controls. Group 1 comprised controls, whereas groups 2, 3 and 4 had patients based on their mean glomerular filtration rate. SPSS 19 was used for data analysis. RESULTS Of the 170 participants, 126(74.1%) were cases and 44(25.9%) were controls. The overall mean age was 55.87±3.48 years and the mean body mass index was 24.25±2.9 kg/m2. Decreased levels of iron and haemoglobin were observed in cases compared to controls (p<0.001), while high serum ferritin was seen in cases compared to the controls (p<0.001). Correspondingly, the soluble transferrin receptor-to-ferritin ratio was significantly decreased in groups 2, 3 and 4 (p<0.001). C...

Pakistan journal of pharmaceutical sciences, 2018

Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications an... more Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications and plasma leptin level is elevated in cardio renal syndrome. We wanted to explore leptin levels in patients with different stages of CKD and find its association with risk of cardiovascular disease. This cross-sectional study was conducted in Nephrology Department of Jinnah Post Graduate Medical Centre (JPMC) from January 2014 to September 2014. Group I comprised of controls (GFR=116±8.3, n = 44) acquired from general population, CKD patients were grouped as II, III and IV respectively with GFR; 85.77±9.9 (n = 42), 53.84±9.9 (n=42) and 20.22±8.4 (n = 42).CKD patients with any inflammatory disease, Diabetes Mellitus and on steroid therapy were excluded. Serum leptin, lipid profile and C reactive proteins (CRP) were measured. Leptin and CRP levels increased significantly with progression of CKD. High density lipoproteins (HDL) to low density lipoproteins (LDL) ratio was significantly high i...

Objective: To estimate and compare dyslipidemia in patients with different stages of chronic kidn... more Objective: To estimate and compare dyslipidemia in patients with different stages of chronic kidney disease as compared to healthy controls and to determine whether dyslipidemia is independently associated with rapid renal impairment. Methods: This study was conducted in department of Biochemistry Basic Medical Institute (BMSI), Jinnah Postgraduate Medical Centre (JPMC) Karachi. A total of 150 participants were recruited for the study from the Nephrology department of JPMC. These were grouped as 30 stage II CKD patient, 30 stage III CKD patient, 30 stage IV CKD patient, 30 stage V CKD patient and 30 normal healthy individuals. Cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, urea and creatinine were measured by commercially available kit method. Statistical analysis was done using SPSS version 11. Results: Serum Cholesterol, Triglyceride and LDL-C among all groups were significantly increased when compared with control p<0.05. Serum HDL-C among all st...

JPMA. The Journal of the Pakistan Medical Association, 2017

To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic ki... more To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease. This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre, Karachi, from January to September 2014, and comprised chronic kidney disease patients and healthy controls. Group 1 comprised controls, whereas groups 2, 3 and 4 had patients based on their mean glomerular filtration rate. SPSS 19 was used for data analysis. Of the 170 participants, 126(74.1%) were cases and 44(25.9%) were controls. The overall mean age was 55.87±3.48 years and the mean body mass index was 24.25±2.9 kg/m2. Decreased levels of iron and haemoglobin were observed in cases compared to controls (p<0.001), while high serum ferritin was seen in cases compared to the controls (p<0.001). Correspondingly, the soluble transferrin receptor-to-ferritin ratio was significantly decreased in groups 2, 3 and 4 (p<0.001). The ratio of soluble transf...

Journal of the Pakistan Medical Association

Objective: To estimate the levels of myeloperoxidase (MPO) in various stages of CKD and correlate... more Objective: To estimate the levels of myeloperoxidase (MPO) in various stages of CKD and correlate them with inflammatory marker (CRP) and lipid profile.Methods: This cross-sectional study was conducted in the Biochemistry Department, Basic Medical Sciences Institute, Jinnah Post Graduate Medical Centre (J.P.M.C.) with collaboration of the Nephrology Department of J.P.M.C from January 2013 to September 2014. 150 participant were allocated into Group A: healthy subjects (GFR >90 ml/min/1.73m2, n=66) and Group B: CKD patients (GFR<90 ml/min/1.73m2, n=84). Serum cholesterol, triglycerides, HDL-c, CRP and myeloperoxidase were estimated. Data was presented in Mean±SD. Comparison of means within groups was performed by Mann-Whitney U test, where p-values <0.05 were considered significant.Results: With mean age of 55.64 ± 5.63 years, weight and BMI, TG, VLDL C-reactive proteins and MPO was significantly higher in in group B (p<0.001), however cholesterol and LDL-C showed no sign...

Pakistan journal of pharmaceutical sciences, 2018

Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications an... more Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications and plasma leptin level is elevated in cardio renal syndrome. We wanted to explore leptin levels in patients with different stages of CKD and find its association with risk of cardiovascular disease. This cross-sectional study was conducted in Nephrology Department of Jinnah Post Graduate Medical Centre (JPMC) from January 2014 to September 2014. Group I comprised of controls (GFR=116±8.3, n = 44) acquired from general population, CKD patients were grouped as II, III and IV respectively with GFR; 85.77±9.9 (n = 42), 53.84±9.9 (n=42) and 20.22±8.4 (n = 42).CKD patients with any inflammatory disease, Diabetes Mellitus and on steroid therapy were excluded. Serum leptin, lipid profile and C reactive proteins (CRP) were measured. Leptin and CRP levels increased significantly with progression of CKD. High density lipoproteins (HDL) to low density lipoproteins (LDL) ratio was significantly high i...

Journal of Bahria University Medical and Dental College, 2021

Objective: To determine differences in eating practices, perceptions, and perceived barriers amon... more Objective: To determine differences in eating practices, perceptions, and perceived barriers among intermediate students of government and private sectors in Karachi. Study design and setting: A cross-sectional study was conducted in six intermediate colleges of Karachi from October to December 2018. Methodology: Total N=390 students aged 16-24 years were selected via non-probability convenience sampling. The study team developed a questionnaire to assess the dietary habits and barriers among the students. Results: Mean BMI of government college students was 20.41 ± 4.15 kg/m2 while that of private college students was 22.25 ± 5.43 kg/m2. The proportion of underweight participants was higher (36.8%) in government college students, and overweight students being higher in private (23.8%). Similar responses were recorded for daily meals and weekly fastfood and fruit consumption. Skipping meals was found out to be a common practice among students. Breakfast was most commonly skipped mea...

Background: Type 2 diabetes mellitus is becoming one of the major health problems worldwide. Espe... more Background: Type 2 diabetes mellitus is becoming one of the major health problems worldwide. Especially in South East Asia, type 2 diabetes has gained critical significance. As pre-diabetes prevalence is increasing worldwide, it has become an important concern to prevent diabetes at an early stage. Trace elements have been gaining attention in improving the glucometabolic conditions like pre-diabetes and diabetes. Zinc and copper are the major trace elements present in the human body and they play a significant role in the pathogenesis of diabetes mellitus and pre-diabetes. Objectives: The purpose of this study was to compare serum zinc and copper levels in type 2 diabetes and pre-diabetes. Methods: This study was conducted in department of Biochemistry BMSI, JPMC Karachi. Total 90 subjects were taken out of which 30 were type 2 diabetics, 30 were pre-diabetics and 30 were normal healthy individuals. Serum fasting glucose was measured by glucose oxidase method. Serum zinc and copper...

Objective: To estimate the levels of myeloperoxidase in various stages of chronic kidney disease,... more Objective: To estimate the levels of myeloperoxidase in various stages of chronic kidney disease, and to correlate them with an inflammatory marker and lipid profile.

JPMA. The Journal of the Pakistan Medical Association, 2017

OBJECTIVE To assess the ratio of soluble transferrin receptor to ferritin in different stages of ... more OBJECTIVE To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease. METHODS This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre, Karachi, from January to September 2014, and comprised chronic kidney disease patients and healthy controls. Group 1 comprised controls, whereas groups 2, 3 and 4 had patients based on their mean glomerular filtration rate. SPSS 19 was used for data analysis. RESULTS Of the 170 participants, 126(74.1%) were cases and 44(25.9%) were controls. The overall mean age was 55.87±3.48 years and the mean body mass index was 24.25±2.9 kg/m2. Decreased levels of iron and haemoglobin were observed in cases compared to controls (p<0.001), while high serum ferritin was seen in cases compared to the controls (p<0.001). Correspondingly, the soluble transferrin receptor-to-ferritin ratio was significantly decreased in groups 2, 3 and 4 (p<0.001). C...

Pakistan journal of pharmaceutical sciences, 2018

Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications an... more Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications and plasma leptin level is elevated in cardio renal syndrome. We wanted to explore leptin levels in patients with different stages of CKD and find its association with risk of cardiovascular disease. This cross-sectional study was conducted in Nephrology Department of Jinnah Post Graduate Medical Centre (JPMC) from January 2014 to September 2014. Group I comprised of controls (GFR=116±8.3, n = 44) acquired from general population, CKD patients were grouped as II, III and IV respectively with GFR; 85.77±9.9 (n = 42), 53.84±9.9 (n=42) and 20.22±8.4 (n = 42).CKD patients with any inflammatory disease, Diabetes Mellitus and on steroid therapy were excluded. Serum leptin, lipid profile and C reactive proteins (CRP) were measured. Leptin and CRP levels increased significantly with progression of CKD. High density lipoproteins (HDL) to low density lipoproteins (LDL) ratio was significantly high i...

Objective: To estimate and compare dyslipidemia in patients with different stages of chronic kidn... more Objective: To estimate and compare dyslipidemia in patients with different stages of chronic kidney disease as compared to healthy controls and to determine whether dyslipidemia is independently associated with rapid renal impairment. Methods: This study was conducted in department of Biochemistry Basic Medical Institute (BMSI), Jinnah Postgraduate Medical Centre (JPMC) Karachi. A total of 150 participants were recruited for the study from the Nephrology department of JPMC. These were grouped as 30 stage II CKD patient, 30 stage III CKD patient, 30 stage IV CKD patient, 30 stage V CKD patient and 30 normal healthy individuals. Cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, urea and creatinine were measured by commercially available kit method. Statistical analysis was done using SPSS version 11. Results: Serum Cholesterol, Triglyceride and LDL-C among all groups were significantly increased when compared with control p<0.05. Serum HDL-C among all st...

JPMA. The Journal of the Pakistan Medical Association, 2017

To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic ki... more To assess the ratio of soluble transferrin receptor to ferritin in different stages of chronic kidney disease. This case-control study was conducted at the Aga Khan University Hospital and the Jinnah Postgraduate Medical Centre, Karachi, from January to September 2014, and comprised chronic kidney disease patients and healthy controls. Group 1 comprised controls, whereas groups 2, 3 and 4 had patients based on their mean glomerular filtration rate. SPSS 19 was used for data analysis. Of the 170 participants, 126(74.1%) were cases and 44(25.9%) were controls. The overall mean age was 55.87±3.48 years and the mean body mass index was 24.25±2.9 kg/m2. Decreased levels of iron and haemoglobin were observed in cases compared to controls (p<0.001), while high serum ferritin was seen in cases compared to the controls (p<0.001). Correspondingly, the soluble transferrin receptor-to-ferritin ratio was significantly decreased in groups 2, 3 and 4 (p<0.001). The ratio of soluble transf...

Journal of the Pakistan Medical Association

Objective: To estimate the levels of myeloperoxidase (MPO) in various stages of CKD and correlate... more Objective: To estimate the levels of myeloperoxidase (MPO) in various stages of CKD and correlate them with inflammatory marker (CRP) and lipid profile.Methods: This cross-sectional study was conducted in the Biochemistry Department, Basic Medical Sciences Institute, Jinnah Post Graduate Medical Centre (J.P.M.C.) with collaboration of the Nephrology Department of J.P.M.C from January 2013 to September 2014. 150 participant were allocated into Group A: healthy subjects (GFR >90 ml/min/1.73m2, n=66) and Group B: CKD patients (GFR<90 ml/min/1.73m2, n=84). Serum cholesterol, triglycerides, HDL-c, CRP and myeloperoxidase were estimated. Data was presented in Mean±SD. Comparison of means within groups was performed by Mann-Whitney U test, where p-values <0.05 were considered significant.Results: With mean age of 55.64 ± 5.63 years, weight and BMI, TG, VLDL C-reactive proteins and MPO was significantly higher in in group B (p<0.001), however cholesterol and LDL-C showed no sign...

Pakistan journal of pharmaceutical sciences, 2018

Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications an... more Chronic kidney disease (CKD) patients are at an increased risk of cardiovascular complications and plasma leptin level is elevated in cardio renal syndrome. We wanted to explore leptin levels in patients with different stages of CKD and find its association with risk of cardiovascular disease. This cross-sectional study was conducted in Nephrology Department of Jinnah Post Graduate Medical Centre (JPMC) from January 2014 to September 2014. Group I comprised of controls (GFR=116±8.3, n = 44) acquired from general population, CKD patients were grouped as II, III and IV respectively with GFR; 85.77±9.9 (n = 42), 53.84±9.9 (n=42) and 20.22±8.4 (n = 42).CKD patients with any inflammatory disease, Diabetes Mellitus and on steroid therapy were excluded. Serum leptin, lipid profile and C reactive proteins (CRP) were measured. Leptin and CRP levels increased significantly with progression of CKD. High density lipoproteins (HDL) to low density lipoproteins (LDL) ratio was significantly high i...