Sachin Mane - Academia.edu (original) (raw)
Papers by Sachin Mane
Marine Pollution Bulletin, 2013
Sixty marine bacteria isolated from pelagic waters were screened for their ability to degrade low... more Sixty marine bacteria isolated from pelagic waters were screened for their ability to degrade low-density polyethylene; among them, three were positive and able to grow in a medium containing polythene as the sole carbon source. The positive isolates were identified as Kocuria palustris M16, Bacillus pumilus M27 and Bacillus subtilis H1584 based on the 16S rRNA gene sequence homology. The weight loss of polyethylene was 1%, 1.5% and 1.75% after 30 days of incubation with the M16, M27 and H1584 isolates, respectively. The maximum (32%) cell surface hydrophobicity was observed in M16, followed by the H1584 and M27 isolates. The viability of the isolates growing on the polyethylene surface was confirmed using a triphenyltetrazolium chloride reduction test. The viability was also correlated with a concomitant increase in the protein density of the biomass. Polyethylene biodegradation was further confirmed by an increase in the Keto Carbonyl Bond Index, the Ester Carbonyl Bond Index and the Vinyl Bond Index, which were calculated from FT-IR spectra.
Porous polymers were obtained and effect of cross-linkers (hydrophilic/hydrophobic), nonsolvating... more Porous polymers were obtained and effect of cross-linkers (hydrophilic/hydrophobic), nonsolvating porogens (n-butanol/n-hexanol) and their concentration on polymer properties were evaluated. Polymers revealed the increase in specific surface area (SSA) with increasing concentration of crosslinker (cross-link density) inversely SSA was decreased for greater concentration of non-solvating porogens. Importantly, MEH-100 [1:3 monomer:porogen (M:P) ratio] demonstrated the highest pore volume (PV) and pore size (PS) of 4.33 cc/g and 0.87 μm, respectively whereas MDH-100 (1:2 M:P) displayed the highest PV and PS of 3.56 cc/g and 0.68 μm, respectively.
Crosslinked polymer embedded Cu/Ag for comparative drug adsorption and kinetics evaluation
International Journal of Polymeric Materials and Polymeric Biomaterials, 2016
ABSTRACT Two-dimensional crosslinked polymer (2-DCP) was synthesized for evaluation of drug adsor... more ABSTRACT Two-dimensional crosslinked polymer (2-DCP) was synthesized for evaluation of drug adsorption and kinetics thereof. Further, polymer properties were evaluated and parameters such as contact time and adsorption isotherm were also studied. Herein, contact time demonstrated 83% and 85% of drug loading in an acidic medium for two-dimensional crosslinked polymer embedded copper and silver (2-DCP-Cu/Ag), respectively in 24 h. Initial 4 h is the exponential drug loading period whereas drug loading was increased gradually after 4 h. Salbutamol loading was well-fitted to Langmuir adsorption isotherm, which indicated a monolayer drug adsorption with respect to 2-DCP-Cu/Ag. Pseudo first- and pseudo second-order kinetics was evaluated to perceive the drug adsorption mechanism and equilibrium adsorption capacity. Monolayer drug adsorption with chemisorption mechanism was observed for 2-DCP-Cu/Ag. In addition to this, decomposition temperature of polymer was 440 and 325°C while glass transition temperature of polymer was 280 and 200°C before and after metal modification, respectively. (A = aqueous phase; B = organic phase; C = drug solution; D = drug loaded polymer; E = enlarged drug loaded polymer.) GRAPHICAL ABSTRACT
Interfacial tension approach toward drug loading with two-dimensional crosslinked polymer embedded gold: Adsorption kinetics evaluation
International Journal of Polymeric Materials and Polymeric Biomaterials, 2016
ABSTRACT Interfacial tension of drugs with hydrophilic polymer (A) embedded gold resulting into s... more ABSTRACT Interfacial tension of drugs with hydrophilic polymer (A) embedded gold resulting into selective drug adsorption, which also affected the drug adsorption kinetics. Two-dimensional crosslinked polymer embedded gold was synthesized for drug loading application in an acidic buffer. Lower interfacial tension of pantoprazole sodium (B) revealed the exponential loading inversely loading was gradual for chloroquine (C) having more interfacial tension with adsorbent. Initial 2 h was the exponential adsorption period for a pantoprazole sodium whereas exponential adsorption begins after 12 h for a chloroquine. Monolayer drug adsorption was obtained because Langmuir adsorption isotherm was obeyed by both drugs. Moreover, pseudo first- and pseudo second-order kinetics was also evaluated which demonstrated that reactive sites of the adsorbent are homogeneous and drug adsorption mechanism is chemisorption and not the physisorption. Thermal analysis was evaluated to confirm the polymer thermostability and glass transition temperature during catalytic applications in thermal reactions. GRAPHICAL ABSTRACT
Role of aliphatic hydrocarbon content in non-solvating porogens toward porosity of cross-linked microbeads
Polymer, 2016
Abstract Megaporous spherical acrylate copolymer beads were synthesized by suspension polymerizat... more Abstract Megaporous spherical acrylate copolymer beads were synthesized by suspension polymerization using non-solvating porogens. Non-solvating porogens with higher aliphatic hydrocarbon content generated megaporous morphology with lower surface area. Surface area increased and inversely megaporosity was decreased with decrease in the aliphatic hydrocarbon content of porogen. Megaporosity (5.47 μm) and pore volume of 5.52 cm 3 /g was obtained with n-decanol. Thermal property of copolymer is a function of type (rigidity/flexibility/elemental composition) and concentration (cross-link density) of monomer and cross-linker. Copolymer containing rigid cross-linker (divinylbenzene) had better thermal stability over copolymer with flexible cross-linker (ethylene dimethacrylate). Further, higher concentration of rigid cross-linker or lower concentration of flexible cross-linker enhanced the thermal stability. Porous polymers are potentially recognized as a solid support for solid-phase synthesis.
Journal of Applied Polymer Science, 2015
Metal-contaminated industrial effluent is a major concern for human health. Therefore, the remova... more Metal-contaminated industrial effluent is a major concern for human health. Therefore, the removal of metal is of primary importance. In this study, metals were selectively extracted from water. Selective metal recovery was studied with a crown-etherbased polymer, wherein the selectivity was observed for strontium over lead. Parameters influencing the metal recovery, such as the contact time, adsorbent dosage, and metal-ion concentration, were evaluated. Interestingly, the adsorption rate of strontium was exponentially increased for the initial 4 h, and lead was adsorbed exponentially after 6 h. Notably, 98% strontium adsorption and 64% lead adsorption were obtained in 24 h. The Langmuir adsorption isotherm was in good agreement and demonstrated that the reactive sites of the adsorbent were homogeneous with monolayer metal adsorption with an adsorbent. The Freundlich adsorption isotherm was not obeyed by both metals. The pseudo-first-order and pseudo-second-order kinetics indicated that strontium was adsorbed by chemisorption and lead was adsorbed by physisorption.
Design and synthesis of cauliflower-shaped hydroxyl functionalized core-shell polymer
Designed Monomers and Polymers, 2015
Conventional crosslinked polymers and homopolymers both have their own limitations. As a result, ... more Conventional crosslinked polymers and homopolymers both have their own limitations. As a result, core–shell polymer was synthesized to obtain cauliflower-shaped and highly hydroxyl functionalized polymer. For the core, acrylate-based copolymers were synthesized by varying crosslinkers and porogens at different crosslink density. Owing to high surface area (554 m2/g), poly(MMA-co-DVB) was used as a core and low-molecular weight (24,600 g/mol) poly(GMA) was used as a shell in core–shell approach. Average particle sizes of the core polymers were in the range of 15–75 μm. In order to evaluate reactivity efficiency of core–shell polymer, hydroxyl content was evaluated with a value of 3.97 mmol/g. Importantly, hydroxyl content demonstrated the successful increase in reactive sites of the core–shell polymer over conventional crosslinked hydroxyl polymer. Notably, synthesized core–shell polymer has more surface area and pore volume which substantially attributes for better polymer efficiency during application. Scanning electron microscopy images revealed the spherical, uniform, and slightly conglomerated properties of core–shell polymer. Due to higher reactivity, insolubility, and more surface area of hydroxyl functionalized core–shell polymer, its use become inevitably essential.
Role of Interfacial Tension of Solvating Diluents and Hydrophilic–Hydrophobic Cross-Linkers in Hyper-Cross-Linked Solid Supports
Industrial & Engineering Chemistry Research, 2015
The properties of a hyper-cross-linked solid support are the outcome of the interfacial tension c... more The properties of a hyper-cross-linked solid support are the outcome of the interfacial tension created by solvating/nonsolvating diluents, the hydrophilicity/hydrophobicity of the cross-linkers, and their concentrations. Interestingly, a more hydrophobic diluent and cross-linker as well as a higher concentration of cross-linker-containing copolymer revealed an increase in surface area. A high surface area and low cross-link density (CLD) polymer illustrated higher epoxy content. Importantly, maximum surface area (533 m2/g) was obtained at high CLD; inversely, epoxy content (1.83 mmol/g) was higher at low CLD polymer. Notably, greater rigidity of cross-linker and its higher concentration increased Tmax and Tg; contrarily, greater flexibility of cross-linker and its concentration attenuated Tmax and Tg. Thermal study demonstrated the thermostability (300 °C) and polymer safe temperature (220 °C). Indeed, a lower solubility parameter difference between polymer and swelling solvent produces a higher polymer–...
Hyperhydrophilic three-dimensional crosslinked beads as an effective drug carrier in acidic medium: adsorption isotherm and kinetics appraisal
New Journal of Chemistry, 2015
Langmuir adsorption isotherm demonstrates monolayer drug loading with hyperhydrophilic three-dime... more Langmuir adsorption isotherm demonstrates monolayer drug loading with hyperhydrophilic three-dimensional crosslinked polymers. Furthermore, the pseudo order kinetics were also evaluated.
Marine Pollution Bulletin, 2013
Sixty marine bacteria isolated from pelagic waters were screened for their ability to degrade low... more Sixty marine bacteria isolated from pelagic waters were screened for their ability to degrade low-density polyethylene; among them, three were positive and able to grow in a medium containing polythene as the sole carbon source. The positive isolates were identified as Kocuria palustris M16, Bacillus pumilus M27 and Bacillus subtilis H1584 based on the 16S rRNA gene sequence homology. The weight loss of polyethylene was 1%, 1.5% and 1.75% after 30 days of incubation with the M16, M27 and H1584 isolates, respectively. The maximum (32%) cell surface hydrophobicity was observed in M16, followed by the H1584 and M27 isolates. The viability of the isolates growing on the polyethylene surface was confirmed using a triphenyltetrazolium chloride reduction test. The viability was also correlated with a concomitant increase in the protein density of the biomass. Polyethylene biodegradation was further confirmed by an increase in the Keto Carbonyl Bond Index, the Ester Carbonyl Bond Index and the Vinyl Bond Index, which were calculated from FT-IR spectra.
Porous polymers were obtained and effect of cross-linkers (hydrophilic/hydrophobic), nonsolvating... more Porous polymers were obtained and effect of cross-linkers (hydrophilic/hydrophobic), nonsolvating porogens (n-butanol/n-hexanol) and their concentration on polymer properties were evaluated. Polymers revealed the increase in specific surface area (SSA) with increasing concentration of crosslinker (cross-link density) inversely SSA was decreased for greater concentration of non-solvating porogens. Importantly, MEH-100 [1:3 monomer:porogen (M:P) ratio] demonstrated the highest pore volume (PV) and pore size (PS) of 4.33 cc/g and 0.87 μm, respectively whereas MDH-100 (1:2 M:P) displayed the highest PV and PS of 3.56 cc/g and 0.68 μm, respectively.
Crosslinked polymer embedded Cu/Ag for comparative drug adsorption and kinetics evaluation
International Journal of Polymeric Materials and Polymeric Biomaterials, 2016
ABSTRACT Two-dimensional crosslinked polymer (2-DCP) was synthesized for evaluation of drug adsor... more ABSTRACT Two-dimensional crosslinked polymer (2-DCP) was synthesized for evaluation of drug adsorption and kinetics thereof. Further, polymer properties were evaluated and parameters such as contact time and adsorption isotherm were also studied. Herein, contact time demonstrated 83% and 85% of drug loading in an acidic medium for two-dimensional crosslinked polymer embedded copper and silver (2-DCP-Cu/Ag), respectively in 24 h. Initial 4 h is the exponential drug loading period whereas drug loading was increased gradually after 4 h. Salbutamol loading was well-fitted to Langmuir adsorption isotherm, which indicated a monolayer drug adsorption with respect to 2-DCP-Cu/Ag. Pseudo first- and pseudo second-order kinetics was evaluated to perceive the drug adsorption mechanism and equilibrium adsorption capacity. Monolayer drug adsorption with chemisorption mechanism was observed for 2-DCP-Cu/Ag. In addition to this, decomposition temperature of polymer was 440 and 325°C while glass transition temperature of polymer was 280 and 200°C before and after metal modification, respectively. (A = aqueous phase; B = organic phase; C = drug solution; D = drug loaded polymer; E = enlarged drug loaded polymer.) GRAPHICAL ABSTRACT
Interfacial tension approach toward drug loading with two-dimensional crosslinked polymer embedded gold: Adsorption kinetics evaluation
International Journal of Polymeric Materials and Polymeric Biomaterials, 2016
ABSTRACT Interfacial tension of drugs with hydrophilic polymer (A) embedded gold resulting into s... more ABSTRACT Interfacial tension of drugs with hydrophilic polymer (A) embedded gold resulting into selective drug adsorption, which also affected the drug adsorption kinetics. Two-dimensional crosslinked polymer embedded gold was synthesized for drug loading application in an acidic buffer. Lower interfacial tension of pantoprazole sodium (B) revealed the exponential loading inversely loading was gradual for chloroquine (C) having more interfacial tension with adsorbent. Initial 2 h was the exponential adsorption period for a pantoprazole sodium whereas exponential adsorption begins after 12 h for a chloroquine. Monolayer drug adsorption was obtained because Langmuir adsorption isotherm was obeyed by both drugs. Moreover, pseudo first- and pseudo second-order kinetics was also evaluated which demonstrated that reactive sites of the adsorbent are homogeneous and drug adsorption mechanism is chemisorption and not the physisorption. Thermal analysis was evaluated to confirm the polymer thermostability and glass transition temperature during catalytic applications in thermal reactions. GRAPHICAL ABSTRACT
Role of aliphatic hydrocarbon content in non-solvating porogens toward porosity of cross-linked microbeads
Polymer, 2016
Abstract Megaporous spherical acrylate copolymer beads were synthesized by suspension polymerizat... more Abstract Megaporous spherical acrylate copolymer beads were synthesized by suspension polymerization using non-solvating porogens. Non-solvating porogens with higher aliphatic hydrocarbon content generated megaporous morphology with lower surface area. Surface area increased and inversely megaporosity was decreased with decrease in the aliphatic hydrocarbon content of porogen. Megaporosity (5.47 μm) and pore volume of 5.52 cm 3 /g was obtained with n-decanol. Thermal property of copolymer is a function of type (rigidity/flexibility/elemental composition) and concentration (cross-link density) of monomer and cross-linker. Copolymer containing rigid cross-linker (divinylbenzene) had better thermal stability over copolymer with flexible cross-linker (ethylene dimethacrylate). Further, higher concentration of rigid cross-linker or lower concentration of flexible cross-linker enhanced the thermal stability. Porous polymers are potentially recognized as a solid support for solid-phase synthesis.
Journal of Applied Polymer Science, 2015
Metal-contaminated industrial effluent is a major concern for human health. Therefore, the remova... more Metal-contaminated industrial effluent is a major concern for human health. Therefore, the removal of metal is of primary importance. In this study, metals were selectively extracted from water. Selective metal recovery was studied with a crown-etherbased polymer, wherein the selectivity was observed for strontium over lead. Parameters influencing the metal recovery, such as the contact time, adsorbent dosage, and metal-ion concentration, were evaluated. Interestingly, the adsorption rate of strontium was exponentially increased for the initial 4 h, and lead was adsorbed exponentially after 6 h. Notably, 98% strontium adsorption and 64% lead adsorption were obtained in 24 h. The Langmuir adsorption isotherm was in good agreement and demonstrated that the reactive sites of the adsorbent were homogeneous with monolayer metal adsorption with an adsorbent. The Freundlich adsorption isotherm was not obeyed by both metals. The pseudo-first-order and pseudo-second-order kinetics indicated that strontium was adsorbed by chemisorption and lead was adsorbed by physisorption.
Design and synthesis of cauliflower-shaped hydroxyl functionalized core-shell polymer
Designed Monomers and Polymers, 2015
Conventional crosslinked polymers and homopolymers both have their own limitations. As a result, ... more Conventional crosslinked polymers and homopolymers both have their own limitations. As a result, core–shell polymer was synthesized to obtain cauliflower-shaped and highly hydroxyl functionalized polymer. For the core, acrylate-based copolymers were synthesized by varying crosslinkers and porogens at different crosslink density. Owing to high surface area (554 m2/g), poly(MMA-co-DVB) was used as a core and low-molecular weight (24,600 g/mol) poly(GMA) was used as a shell in core–shell approach. Average particle sizes of the core polymers were in the range of 15–75 μm. In order to evaluate reactivity efficiency of core–shell polymer, hydroxyl content was evaluated with a value of 3.97 mmol/g. Importantly, hydroxyl content demonstrated the successful increase in reactive sites of the core–shell polymer over conventional crosslinked hydroxyl polymer. Notably, synthesized core–shell polymer has more surface area and pore volume which substantially attributes for better polymer efficiency during application. Scanning electron microscopy images revealed the spherical, uniform, and slightly conglomerated properties of core–shell polymer. Due to higher reactivity, insolubility, and more surface area of hydroxyl functionalized core–shell polymer, its use become inevitably essential.
Role of Interfacial Tension of Solvating Diluents and Hydrophilic–Hydrophobic Cross-Linkers in Hyper-Cross-Linked Solid Supports
Industrial & Engineering Chemistry Research, 2015
The properties of a hyper-cross-linked solid support are the outcome of the interfacial tension c... more The properties of a hyper-cross-linked solid support are the outcome of the interfacial tension created by solvating/nonsolvating diluents, the hydrophilicity/hydrophobicity of the cross-linkers, and their concentrations. Interestingly, a more hydrophobic diluent and cross-linker as well as a higher concentration of cross-linker-containing copolymer revealed an increase in surface area. A high surface area and low cross-link density (CLD) polymer illustrated higher epoxy content. Importantly, maximum surface area (533 m2/g) was obtained at high CLD; inversely, epoxy content (1.83 mmol/g) was higher at low CLD polymer. Notably, greater rigidity of cross-linker and its higher concentration increased Tmax and Tg; contrarily, greater flexibility of cross-linker and its concentration attenuated Tmax and Tg. Thermal study demonstrated the thermostability (300 °C) and polymer safe temperature (220 °C). Indeed, a lower solubility parameter difference between polymer and swelling solvent produces a higher polymer–...
Hyperhydrophilic three-dimensional crosslinked beads as an effective drug carrier in acidic medium: adsorption isotherm and kinetics appraisal
New Journal of Chemistry, 2015
Langmuir adsorption isotherm demonstrates monolayer drug loading with hyperhydrophilic three-dime... more Langmuir adsorption isotherm demonstrates monolayer drug loading with hyperhydrophilic three-dimensional crosslinked polymers. Furthermore, the pseudo order kinetics were also evaluated.