Safak Karacay - Academia.edu (original) (raw)

Papers by Safak Karacay

Clinical medicine insights, 2023

Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduct... more Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We present a 13-year-old child who admitted with a dull right upper quadrant pain that started 3 weeks before her referral. Several medications were given but they did not change the intensity and the frequency of the pain. Her physical examination was nonspecific except for slight right upper quadrant tenderness. The imaging studies revealed a sewing pin perforating the stomach and gallbladder. The patient was treated with a successful operation, and no postoperative complications were observed. To our knowledge, this is the first case of a sharp foreign body gallbladder perforation in a child. 1.

Premature ejaculation (PE) is the most common male sexual dysfunction. The prevalence rates of PE... more Premature ejaculation (PE) is the most common male sexual dysfunction. The prevalence rates of PE range from 20 % to 40 % among sexually active men in Europe and Asia [1–5]. PE causes interper-

Case Reports in Clinical Pathology, 2016

Supportive Care Cancer

To determine the efficacy of a mouthwash in relieving mucositis-induced discomfort in patients re... more To determine the efficacy of a mouthwash in relieving mucositis-induced discomfort in patients receiving chemotherapy, 31 (16 male, 15 female) with a mean age of 45 (range 16-80) were given an in-house three-drug (lidocaine, diphenhydramine and sodium bicarbonate in normal saline) mouthwash when they developed mucositis of any severity. The complications were assessed on the CALGB (Cancer and Leukemia Group B) scale. The response to the mouthwash was reported on a self-assessment scale. Patients' response data were analyzed with reference to: (1) relief throughout the duration of mucositis and (2) relief during the worst stage (for each episode) of mucositis. Five patients with fungal, viral or bacterial oral infection were excluded from study. Overall, 4 patients had grade I, 16 patients had grade II, 10 patients had grade III and 1 patient had grade IV mucositis. The average duration of mucositis was 7.9 days (range 3-23 days), and the mean duration of the worst stage of mucos...

Central European journal of urology, 2014

Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (... more Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT. A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test. Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME. A strong correlation between IELT...

Çocuk Cerrahisi Dergisi, 2007

Most intraabdominal cysts seeni of infancy are, ovarian cysts in females which mostly regress bef... more Most intraabdominal cysts seeni of infancy are, ovarian cysts in females which mostly regress before the first year of life (1,2).However,Complicated or large intraabdominal cysts might necessitate surgical intervention. The high diagnostic frequency in this entity may be addressed to increased number of high quality ultrasound performed at the antenatal period. We report a female neanate with antenatally diagnosed huge intraabdominal cyst.

Özet Amaç: Travmalar›n % 90'› oluflturan künt travmalar ara-s›nda önemsiz gibi görünen; ancak küç... more Özet Amaç: Travmalar›n % 90'› oluflturan künt travmalar ara-s›nda önemsiz gibi görünen; ancak küçük perine kesikle-rinden solid organ hasar›na kadar de¤iflen yaralanmalar oluflturabilen bisiklet travmalar›n›n çocuklardaki klinik özelliklerinin vurgulanmas› amaçlanm›flt›r.

Central European journal of urology, 2014

Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (... more Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT. A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test. Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME. A strong correlation between IELT...

Journal of Laparoendoscopic & Advanced Surgical Techniques Part B, Videoscopy, 2016

Yeditepe Medical Journal, 2012

Yeditepe Medical Journal, 2012

Annals of Pediatric Surgery, 2012

Pyogenic granuloma (PG) is a non-neoplastic inflammatory hyperplasia that may be encountered in a... more Pyogenic granuloma (PG) is a non-neoplastic inflammatory hyperplasia that may be encountered in any part of the body including the oral mucosa. The onset of symptoms is mostly observed at adolescence in children. In this presentation, the second youngest case of gingival PG in the literature is reported to provide an insight into early neonatal gingival masses, which may be a stress factor for both the parents and the physician. A 4-month-old male baby was referred to our clinic with the complaint of erythema and swelling at the upper gingival floor, which was first observed 2 months ago by his mother before his admission. At physical examination, a soft, hyperemic mucosal lesion was observed that protruded from the upper gingival floor. After the excision, granulomatous-type PG was diagnosed. The excision site healed and the postoperative period was uneventful. The gingiva is the most common intraoral site of PG as in our case, but this localization is specific for the older age group rather than in infants. Intraoral lesions of neonatal period are unfamiliar to the parents resulting in their anxiety. The PG is a benign lesion that can be healed completely, with good cosmetic results. Ann Pediatr Surg 8:93-94 c 2012 Annals of Pediatric Surgery. Annals of Pediatric Surgery 2012, 8:93-94

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2003

Foreign bodies (FB) in the airway require prompt removal in children. We reviewed our experience ... more Foreign bodies (FB) in the airway require prompt removal in children. We reviewed our experience in patients with suspected airway FB. A retrospective study was conducted in 189 consecutive children who admitted to the Department of Pediatric Surgery, SSK Tepecik Training Hospital between 1997-2001. Patients data on presentation, bronchoscopy findings and results were obtained. Of the 189 bronchoscopies, 127 (67.2%) showed FB which are commonly located in the right mainstem bronchus. Most of FB were nonradiopaque. Pips and hazelnuts were the most common FB. Mean hospital stay was 2.5 days. Many patients (151 out of 189; 79.9%) had transient stridor or fever that ceased within 24 hours after bronchoscopy. No mortality was observed rin relation with bronchoscopy. Chest radiographs of the children with FB in the airways are inconclusive. Children with a history of small particles in their mouths and subsequently showing wheezing, or choking episode should undergo prompt bronchoscopy. C...

Journal of Perinatal Medicine, 2000

Cervical teratomas are rare tumors during the prenatal period. Cervical teratomas account for 1.5... more Cervical teratomas are rare tumors during the prenatal period. Cervical teratomas account for 1.5-5.5% of all pediatric teratomas. Both mortality and morbidity are significantly high because of airway obstruction due to a mass effect of the tumor although good results are achieved with total excision of the mass. Antenatal diagnosis by routine ultrasound (US) screening helps in preparing a team to provide airway support and surgery. We present two cases of cervical teratomas with total excision and cure and a postmortem study from our pathology laboratory. The third case, the female infant who died soon after birth, demonstrates the paramount importance of antenatal diagnosis.

The Journal of international medical research, 2014

To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam ... more To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam for the prevention of emergence agitation in children. Children undergoing urological surgery with sevoflurane anaesthesia received oral midazolam 40 min before induction and were then randomly assigned to receive 2 mg/kg ketamine, 10 µg/kg alfentanil or 1 ml isotonic saline intranasally. Parental separation status and mask acceptance were assessed preoperatively. Emergence agitation was evaluated using a paediatric anaesthesia emergence delirium (PAED) score. Data from 78 children were evaluated in the study. There were no significant differences between the groups in demographic characteristics, recovery times or parental separation scores. Mask acceptance was significantly better in the ketamine group than in the saline group. The mean PAED score in the ketamine group was significantly better than in the other two groups, but was similar in the saline and alfentanil groups. The incide...

Aim An obvious scar on the neck may appear following the open surgery for congenital muscular tor... more Aim An obvious scar on the neck may appear following the open surgery for congenital muscular torticollis (CMT). The cosmetic result may displease the patient and the family. In this study, we describe a minimally invasive technique, para-axillary subcutaneous endoscopic approach (PASEA) in CMT. Patients and Methods A total of 11 children (seven girls and four boys with the age range between 1 and 15 years) were operated for torticollis by PASEA. All patients had facial asymmetry and head and neck postural abnormality. Following an incision at the ipsilateral para-axillary region, a subcutaneous cavernous working space is formed toward sternocleidomastoid (SCM) muscle. The muscle and fascia are cut by cautery under endoscopic vision. The patients had postoperative 2nd-week and 3rd-month visits. The incision scar, inspection, and palpation findings of the region, head posture, and shoulder position of the affected side were considered in evaluation of the cosmetic outcome. Preoperative and postoperative range of motion of the head and neck were compared for functional outcome. Results We preferred single incision surgery in our last two patients; the rest had double para-axillary incision for port insertion. Incomplete transection of the muscle was not observed. There was no serious complication. Postoperatively, head posture and shoulder elevation were corrected significantly. Range of motion of the head was improved. Postoperatively, all the patients had rotation capacity with more than 30 degrees. The range of postoperative flexion and extension movements was between 45 and 60 degrees. Conclusions The open surgery techniques of CMT causes visible lifelong incision scar on the neck. PASEA leaves a cosmetically hidden scar in the axillary region. A single incision surgery is also possible. A well-formed cavernous working space is needed. External manual palpation, delicate dissection, and cutting of SCM muscle with cautery are the important components of the procedure. Surgeons having experience in pediatric minimal invasive surgery may consider PASEA as an alternative to the open approach in CMT. The surgeon should be familiar with surgical anatomy of the neck and must be highly competent in management of possible complications in the region.

Clinical medicine insights, 2023

Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduct... more Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We present a 13-year-old child who admitted with a dull right upper quadrant pain that started 3 weeks before her referral. Several medications were given but they did not change the intensity and the frequency of the pain. Her physical examination was nonspecific except for slight right upper quadrant tenderness. The imaging studies revealed a sewing pin perforating the stomach and gallbladder. The patient was treated with a successful operation, and no postoperative complications were observed. To our knowledge, this is the first case of a sharp foreign body gallbladder perforation in a child. 1.

Premature ejaculation (PE) is the most common male sexual dysfunction. The prevalence rates of PE... more Premature ejaculation (PE) is the most common male sexual dysfunction. The prevalence rates of PE range from 20 % to 40 % among sexually active men in Europe and Asia [1–5]. PE causes interper-

Case Reports in Clinical Pathology, 2016

Supportive Care Cancer

To determine the efficacy of a mouthwash in relieving mucositis-induced discomfort in patients re... more To determine the efficacy of a mouthwash in relieving mucositis-induced discomfort in patients receiving chemotherapy, 31 (16 male, 15 female) with a mean age of 45 (range 16-80) were given an in-house three-drug (lidocaine, diphenhydramine and sodium bicarbonate in normal saline) mouthwash when they developed mucositis of any severity. The complications were assessed on the CALGB (Cancer and Leukemia Group B) scale. The response to the mouthwash was reported on a self-assessment scale. Patients' response data were analyzed with reference to: (1) relief throughout the duration of mucositis and (2) relief during the worst stage (for each episode) of mucositis. Five patients with fungal, viral or bacterial oral infection were excluded from study. Overall, 4 patients had grade I, 16 patients had grade II, 10 patients had grade III and 1 patient had grade IV mucositis. The average duration of mucositis was 7.9 days (range 3-23 days), and the mean duration of the worst stage of mucos...

Central European journal of urology, 2014

Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (... more Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT. A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test. Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME. A strong correlation between IELT...

Çocuk Cerrahisi Dergisi, 2007

Most intraabdominal cysts seeni of infancy are, ovarian cysts in females which mostly regress bef... more Most intraabdominal cysts seeni of infancy are, ovarian cysts in females which mostly regress before the first year of life (1,2).However,Complicated or large intraabdominal cysts might necessitate surgical intervention. The high diagnostic frequency in this entity may be addressed to increased number of high quality ultrasound performed at the antenatal period. We report a female neanate with antenatally diagnosed huge intraabdominal cyst.

Özet Amaç: Travmalar›n % 90'› oluflturan künt travmalar ara-s›nda önemsiz gibi görünen; ancak küç... more Özet Amaç: Travmalar›n % 90'› oluflturan künt travmalar ara-s›nda önemsiz gibi görünen; ancak küçük perine kesikle-rinden solid organ hasar›na kadar de¤iflen yaralanmalar oluflturabilen bisiklet travmalar›n›n çocuklardaki klinik özelliklerinin vurgulanmas› amaçlanm›flt›r.

Central European journal of urology, 2014

Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (... more Premature ejaculation (PE) is the most common male sexual dysfunction. Monosymptomatic enuresis (ME) is nocturnal bed wetting, without any daytime symptoms. Recent clinical studies report an association between lifelong PE and ME. The purpose of this study was to compare the intravaginal ejaculatory time (IELT) between lifelong PE in men with and without ME. The goal was to determine if there is an association between the severity of ME and of IELT. A total of 137 men with lifelong PE were included in this study. Subjects were asked if they had childhood ME. The characteristics and mean IELTs of patients with and without ME were compared using the student's t-test, and the correlation between severity of ME and IELT was assessed with trend test. Of the 137 lifelong PE patients, 57 reported ME. There was a strong negative correlation in patients with ME between the severity of enuresis and IELT, with IELT being shorter in patients with severe ME. A strong correlation between IELT...

Journal of Laparoendoscopic & Advanced Surgical Techniques Part B, Videoscopy, 2016

Yeditepe Medical Journal, 2012

Yeditepe Medical Journal, 2012

Annals of Pediatric Surgery, 2012

Pyogenic granuloma (PG) is a non-neoplastic inflammatory hyperplasia that may be encountered in a... more Pyogenic granuloma (PG) is a non-neoplastic inflammatory hyperplasia that may be encountered in any part of the body including the oral mucosa. The onset of symptoms is mostly observed at adolescence in children. In this presentation, the second youngest case of gingival PG in the literature is reported to provide an insight into early neonatal gingival masses, which may be a stress factor for both the parents and the physician. A 4-month-old male baby was referred to our clinic with the complaint of erythema and swelling at the upper gingival floor, which was first observed 2 months ago by his mother before his admission. At physical examination, a soft, hyperemic mucosal lesion was observed that protruded from the upper gingival floor. After the excision, granulomatous-type PG was diagnosed. The excision site healed and the postoperative period was uneventful. The gingiva is the most common intraoral site of PG as in our case, but this localization is specific for the older age group rather than in infants. Intraoral lesions of neonatal period are unfamiliar to the parents resulting in their anxiety. The PG is a benign lesion that can be healed completely, with good cosmetic results. Ann Pediatr Surg 8:93-94 c 2012 Annals of Pediatric Surgery. Annals of Pediatric Surgery 2012, 8:93-94

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2003

Foreign bodies (FB) in the airway require prompt removal in children. We reviewed our experience ... more Foreign bodies (FB) in the airway require prompt removal in children. We reviewed our experience in patients with suspected airway FB. A retrospective study was conducted in 189 consecutive children who admitted to the Department of Pediatric Surgery, SSK Tepecik Training Hospital between 1997-2001. Patients data on presentation, bronchoscopy findings and results were obtained. Of the 189 bronchoscopies, 127 (67.2%) showed FB which are commonly located in the right mainstem bronchus. Most of FB were nonradiopaque. Pips and hazelnuts were the most common FB. Mean hospital stay was 2.5 days. Many patients (151 out of 189; 79.9%) had transient stridor or fever that ceased within 24 hours after bronchoscopy. No mortality was observed rin relation with bronchoscopy. Chest radiographs of the children with FB in the airways are inconclusive. Children with a history of small particles in their mouths and subsequently showing wheezing, or choking episode should undergo prompt bronchoscopy. C...

Journal of Perinatal Medicine, 2000

Cervical teratomas are rare tumors during the prenatal period. Cervical teratomas account for 1.5... more Cervical teratomas are rare tumors during the prenatal period. Cervical teratomas account for 1.5-5.5% of all pediatric teratomas. Both mortality and morbidity are significantly high because of airway obstruction due to a mass effect of the tumor although good results are achieved with total excision of the mass. Antenatal diagnosis by routine ultrasound (US) screening helps in preparing a team to provide airway support and surgery. We present two cases of cervical teratomas with total excision and cure and a postmortem study from our pathology laboratory. The third case, the female infant who died soon after birth, demonstrates the paramount importance of antenatal diagnosis.

The Journal of international medical research, 2014

To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam ... more To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam for the prevention of emergence agitation in children. Children undergoing urological surgery with sevoflurane anaesthesia received oral midazolam 40 min before induction and were then randomly assigned to receive 2 mg/kg ketamine, 10 µg/kg alfentanil or 1 ml isotonic saline intranasally. Parental separation status and mask acceptance were assessed preoperatively. Emergence agitation was evaluated using a paediatric anaesthesia emergence delirium (PAED) score. Data from 78 children were evaluated in the study. There were no significant differences between the groups in demographic characteristics, recovery times or parental separation scores. Mask acceptance was significantly better in the ketamine group than in the saline group. The mean PAED score in the ketamine group was significantly better than in the other two groups, but was similar in the saline and alfentanil groups. The incide...

Aim An obvious scar on the neck may appear following the open surgery for congenital muscular tor... more Aim An obvious scar on the neck may appear following the open surgery for congenital muscular torticollis (CMT). The cosmetic result may displease the patient and the family. In this study, we describe a minimally invasive technique, para-axillary subcutaneous endoscopic approach (PASEA) in CMT. Patients and Methods A total of 11 children (seven girls and four boys with the age range between 1 and 15 years) were operated for torticollis by PASEA. All patients had facial asymmetry and head and neck postural abnormality. Following an incision at the ipsilateral para-axillary region, a subcutaneous cavernous working space is formed toward sternocleidomastoid (SCM) muscle. The muscle and fascia are cut by cautery under endoscopic vision. The patients had postoperative 2nd-week and 3rd-month visits. The incision scar, inspection, and palpation findings of the region, head posture, and shoulder position of the affected side were considered in evaluation of the cosmetic outcome. Preoperative and postoperative range of motion of the head and neck were compared for functional outcome. Results We preferred single incision surgery in our last two patients; the rest had double para-axillary incision for port insertion. Incomplete transection of the muscle was not observed. There was no serious complication. Postoperatively, head posture and shoulder elevation were corrected significantly. Range of motion of the head was improved. Postoperatively, all the patients had rotation capacity with more than 30 degrees. The range of postoperative flexion and extension movements was between 45 and 60 degrees. Conclusions The open surgery techniques of CMT causes visible lifelong incision scar on the neck. PASEA leaves a cosmetically hidden scar in the axillary region. A single incision surgery is also possible. A well-formed cavernous working space is needed. External manual palpation, delicate dissection, and cutting of SCM muscle with cautery are the important components of the procedure. Surgeons having experience in pediatric minimal invasive surgery may consider PASEA as an alternative to the open approach in CMT. The surgeon should be familiar with surgical anatomy of the neck and must be highly competent in management of possible complications in the region.