Sai Nayak - Academia.edu (original) (raw)
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Papers by Sai Nayak
Journal of The Electrochemical Society
Engineering nanomaterials for non-invasive electrochemical detection of dopamine (DA) in biologic... more Engineering nanomaterials for non-invasive electrochemical detection of dopamine (DA) in biological samples has been daunting. We report a novel gold-curcumin (Au-CM) nanocomposite as an electrochemical sensor for real-time ultra-selective detection of DA in urine samples. Gold nanoparticles (∼2–3 nm) encased in porous curcumin (CM) network on the surface of a glassy carbon electrode were synthesized via a galvanostatic method and used as the electrochemical sensor. The modified electrode exhibited excellent sensitivity and selectivity toward DA sensing with a record-low limit of detection (LOD) of 3 pM (signal-to-noise ratio of 3). Our DFT-D3 calculations revealed a higher (by 23.3 kJ mol−1) adsorption energy of DA on the Au-CM nanocomposite than on the bare Au nanocluster. Furthermore, a wide range of detection 1 pM − 400 μM (R 2 = 0.99) was achieved at pH 6. Real-time DA detection was successfully performed in pharmaceutical formulations and urine samples with a single step of di...
Materials Chemistry and Physics
ECS Meeting Abstracts, 2021
Physica E: Low-dimensional Systems and Nanostructures, 2021
Abstract Metal-dielectric hybrid nanostructures have recently drawn interest because of their dir... more Abstract Metal-dielectric hybrid nanostructures have recently drawn interest because of their direct coupling between metal surface plasmon resonance and dielectric electric dipoles leading to hybridized modes resulting in low losses and high field enhancements. Surface plasmon-coupled emission is a similar phenomenon that exploits the surface plasmon polaritons generated at the junction of dielectric and metal planar boundary. In this regard, we propose and demonstrate the use of dielectric nanotubes – Halloysite (HS) as spacer materials on metallic silver thin film. In this work, we selectively modified HS by acid or base treatment. Further they were loaded with silver nanoparticles (AgNPs) by solution deposition (in-situ method), thereby creating a metal-dielectric hybrid material. Selective acid and base treatment of HS nanotubes affected the surface charge distribution and aggregation of the nanotubes. Better dispersion ability and higher electronegativity behaviour was observed in base-treated HS that aided in higher loading of AgNPs. Enhanced interparticle plasmon coupling and better transmission of plasmon mediating energy was observed in base-treated HS-Ag that augmented dipole emission. The enhanced plasmon-coupled emission of HS-Ag nanostructures were also explored using a low-cost mobile phone as a detector to simplify the process of fluorescence detection.
General Hospital Psychiatry, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Journal of The Electrochemical Society
Engineering nanomaterials for non-invasive electrochemical detection of dopamine (DA) in biologic... more Engineering nanomaterials for non-invasive electrochemical detection of dopamine (DA) in biological samples has been daunting. We report a novel gold-curcumin (Au-CM) nanocomposite as an electrochemical sensor for real-time ultra-selective detection of DA in urine samples. Gold nanoparticles (∼2–3 nm) encased in porous curcumin (CM) network on the surface of a glassy carbon electrode were synthesized via a galvanostatic method and used as the electrochemical sensor. The modified electrode exhibited excellent sensitivity and selectivity toward DA sensing with a record-low limit of detection (LOD) of 3 pM (signal-to-noise ratio of 3). Our DFT-D3 calculations revealed a higher (by 23.3 kJ mol−1) adsorption energy of DA on the Au-CM nanocomposite than on the bare Au nanocluster. Furthermore, a wide range of detection 1 pM − 400 μM (R 2 = 0.99) was achieved at pH 6. Real-time DA detection was successfully performed in pharmaceutical formulations and urine samples with a single step of di...
Materials Chemistry and Physics
ECS Meeting Abstracts, 2021
Physica E: Low-dimensional Systems and Nanostructures, 2021
Abstract Metal-dielectric hybrid nanostructures have recently drawn interest because of their dir... more Abstract Metal-dielectric hybrid nanostructures have recently drawn interest because of their direct coupling between metal surface plasmon resonance and dielectric electric dipoles leading to hybridized modes resulting in low losses and high field enhancements. Surface plasmon-coupled emission is a similar phenomenon that exploits the surface plasmon polaritons generated at the junction of dielectric and metal planar boundary. In this regard, we propose and demonstrate the use of dielectric nanotubes – Halloysite (HS) as spacer materials on metallic silver thin film. In this work, we selectively modified HS by acid or base treatment. Further they were loaded with silver nanoparticles (AgNPs) by solution deposition (in-situ method), thereby creating a metal-dielectric hybrid material. Selective acid and base treatment of HS nanotubes affected the surface charge distribution and aggregation of the nanotubes. Better dispersion ability and higher electronegativity behaviour was observed in base-treated HS that aided in higher loading of AgNPs. Enhanced interparticle plasmon coupling and better transmission of plasmon mediating energy was observed in base-treated HS-Ag that augmented dipole emission. The enhanced plasmon-coupled emission of HS-Ag nanostructures were also explored using a low-cost mobile phone as a detector to simplify the process of fluorescence detection.
General Hospital Psychiatry, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.