Said BOUJRAF - Academia.edu (original) (raw)

Papers by Said BOUJRAF

Journal of neurosciences in rural practice, Feb 19, 2024

BMC public health, Jan 27, 2024

Background Self-medication during pregnancy is of great interest. The use of drugs during pregnan... more Background Self-medication during pregnancy is of great interest. The use of drugs during pregnancy requires a careful reflection on the benefits to the mother and the risks to the fetus. Selecting a drug or drugs for treating pregnant women can be difficult for clinicians owing to the various pharmacokinetic and physiological changes encountered during pregnancy. This systematic review and meta-analysis aimed to estimate the pooled prevalence of self-medication and associated factors among women during pregnancy. Methods Searches were carried out at PubMed, Science Direct, Web of Science, and Google Scholar. The quality of the studies and the risk of bias were analyzed using the Joanna Briggs Critical Appraisal Checklist for Analytical Cross-Sectional Studies instrument. The extracted data were tabulated and analyzed qualitatively and quantitatively through meta-analysis. Results The overall prevalence of self-medication among pregnant women was 44.50% (95% CI: 38.92-50.23). Subgroup analyses showed differences in self-medication prevalence influenced by region, county income, and study design. The Heterogeneity, assessed by the statistical test I2 varied from 96 to 99% and was statistically significant. The result of this funnel plot showed that the funnel plot was symmetry with p-value = 0.36, and there is no publication bias. Conclusion The results obtained from this study showed that the prevalence of self-medication among pregnant women is relatively high. This requires effective measures and interventions to reduce self-medication. Trial registration ID = CRD42 02231 2333.

Journal of medical signals and sensors, 2018

Background: A color mapping of fiber tract orientation using diffusion tensor imaging (DTI) can b... more Background: A color mapping of fiber tract orientation using diffusion tensor imaging (DTI) can be prominent in clinical practice. The goal of this paper is to perform a comparative study of visualized diffusion anisotropy in the human brain anatomical entities using three different color-mapping techniques based on diffusion-weighted imaging (DWI) and DTI. Methods: The first technique is based on calculating a color map from DWIs measured in three perpendicular directions. The second technique is based on eigenvalues derived from the diffusion tensor. The last technique is based on three eigenvectors corresponding to sorted eigenvalues derived from the diffusion tensor. All magnetic resonance imaging measurements were achieved using a 1.5 Tesla Siemens Vision whole body imaging system. A single-shot DW echoplanar imaging sequence used a Stejskal-Tanner approach. Trapezoidal diffusion gradients are used. The slice orientation was transverse. The basic measurement yielded a set of 13 images. Each series consists of a single image without diffusion weighting, besides two DWIs for each of the next six noncollinear magnetic field gradient directions. Results: The three types of color maps were calculated consequently using the DWI obtained and the DTI. Indeed, we established an excellent similarity between the image data in the color maps and the fiber directions of known anatomical structures (e.g., corpus callosum and gray matter). Conclusions: In the meantime, rotationally invariant quantities such as the eigenvectors of the diffusion tensor reflected better, the real orientation found in the studied tissue.

Sang Thrombose Vaisseaux, Jun 1, 2023

Medecine Nucleaire-imagerie Fonctionnelle Et Metabolique, Dec 1, 2014

ABSTRACT The multimodal magnetic resonance imaging (MMRI) has an important role in cancer care. T... more ABSTRACT The multimodal magnetic resonance imaging (MMRI) has an important role in cancer care. This non-invasive and non-ionizing technique provides vital information for the diagnosis and answers to various questions of clinicians before, during and after treatment. The MMRI can specify the localization expanding process; it allows establishing the differential diagnosis of a brain tumor and a circumscribed lesion of another type, to approach the diagnosis of the tumor lesion nature as well as establishing the histological grade of glial tumor in view of lesion monitoring after treatment. The multimodal magnetic resonance imaging has a major contribution to the management progress of the brain tumors. Thus, this paper reviews the value of these MRI modalities in the diagnosis, management and therapy of brain tumors.

PubMed, 2008

Tuberculosis is endemic in developing countries. However, skull tuberculosis is uncommon with few... more Tuberculosis is endemic in developing countries. However, skull tuberculosis is uncommon with few cases reported in the literature. We report a 10-year-old boy admitted for a left parietal painless swelling. A CT scan demonstrated a left parietal bony defect, destroying both inner and outer tables. This was associated with an enhanced epidural collection and scalp swelling. The patient was operated, and the microscopic examination revealed typical tuberculosis granuloma. The clinical presentation and management of this rare location of tuberculosis are discussed.

Frontiers in Neuroscience, 2010

The tuberculosis of the elbow is an exceptional localization of the mycobacterium tuberculosis. T... more The tuberculosis of the elbow is an exceptional localization of the mycobacterium tuberculosis. This raises a diagnostic problem which is often tardy. This could therefore, have important consequences. We report 2 cases of chronic arthritis of the elbow, where the diagnosis was built on the anatomic-pathology investigation. In addition to the surgical synovectomy, the antibacillar treatment had stopped the infection. This led to stiffness of the elbow in one of these two patients. Through these observations, we discuss the rarity of this tuberculosis localization which must be treated promptly to avoid heavy consequences.

DOAJ (DOAJ: Directory of Open Access Journals), Aug 9, 2022

Disability and Rehabilitation, Nov 18, 2021

PURPOSE To report on the methodology, participant characteristics, and associations of four most ... more PURPOSE To report on the methodology, participant characteristics, and associations of four most frequent environmental barriers with health conditions, general health and quality of life (QoL) in the very first systematic data collection in people with spinal cord injury (SCI) in Morocco. MATERIALS AND METHODS We obtained data from 385 participants of the cross-sectional Moroccan SCI community survey (MorSCI). We used descriptive statistics to describe participant characteristics and regression models to investigate associations of the five most frequently reported environmental barriers with health conditions (secondary conditions, pain intensity, mental health), general health and QoL. RESULTS The most frequently reported environmental barriers were "lack of public services" (92.5%), "financial strain" (93.0%), restricted access to "public transportation" (85.5%), "public places" (83.9%) and "private places" (84.7%). People who perceived those factors as barriers also reported more secondary conditions, higher pain intensity, lower mental health, lower general health, and lower QoL. CONCLUSIONS This study on Moroccans with SCI found that environmental barriers detract from health and QoL. Given that environmental barriers are potentially modifiable, policy interventions present powerful tools to reduce barriers and potentially increase health and QoL in this vulnerable population.IMPLICATIONS FOR REHABILITATIONPublic policy on the construction of transportation and public places is important to make the physical environment accessible for wheelchair users to support their participation in society.The provision of adequate rehabilitation services and specialized post-acute rehabilitation units for people with SCI in Morocco is urgently needed, not only to contribute to health and QoL but also to contribute to their abilities to overcome environmental barriers.Adequate state services including universal health coverage and access to rehabilitation services and assistive devices or adapted tools must be a priority on the policy level to facilitate activities of daily living and reduce barriers.Improving the skills and knowledge of health professionals in SCI rehabilitation and guide policy makers to promote patient education and self-advocacy in the meantime, may help reduce the gap between needs of people with SCI and available support.

PubMed, Apr 1, 2011

Objective: To estimate patient preoperative anxiety, and determine associated factors. Methods: F... more Objective: To estimate patient preoperative anxiety, and determine associated factors. Methods: Fifty surgical patients were investigated prospectively at the University Hospital, Rabat, Morocco between January and June 2008. Ethical Committee approval was obtained prior to conducting this study. A short version of the Hamilton scale was used. Descriptive statistics, student`s t-test, and ANOVA were performed to probe the sociodemographic impact factors on Hamilton scores. We investigated scores superior to 14 indicating a pathologic anxiety situation. A logistic regression was carried out by including all variables; the significant threshold was 0.15 in single variable analysis, and we retained a significant threshold of 0.05 in the final model. Results: A significant decrease in anxiety from the preoperative to the postoperative stage was observed in all patients of merged surgery groups. Females had higher preoperational anxiety compared with males. A longer hospitalization stay and lower knowledge of patients regarding their pathologies were the main factors that increased the anxiety scores towards a pathological anxiety state. This applied to all patients, including higher education and prosperous social classes. Conclusion: Patient sociodemographic, psychological history, and surgery type have to be considered for identifying patients at risk for developing anxiety before and after surgery. Psychological support has to be established to avoid additional suffering of the patient from anxiety.

African Journal of Neurological Sciences, Dec 8, 2017

Introduction: Les auteurs rapportent une cause exceptionnelle d’epilepsie a declaration tardive, ... more Introduction: Les auteurs rapportent une cause exceptionnelle d’epilepsie a declaration tardive, liee a un double osteolipome intracrânien cortical. L’aspect en imagerie ne souffre de difficultes diagnostiques, et la recherche des malformations associees est capitale en imagerie. La prise en charge est essentiellement medicale, le recours a la chirurgie est rarement indique. Observation: Il s’agit d’un jeune adulte de 19 ans sans antecedents medico-chirurgicaux particuliers, admis pour bilan de crises convulsives, chez qui l’imagerie en coupe a confirme le diagnostic d’un osteolipome cortical bifocal. La prise en charge s’est resumee a un traitement medical anticonvulsivant avec une evolution favorable. Conclusion: En conclusion, il s’agit de la premiere observation de la litterature medicale rapportant un osteolipome cortical bifocal associe a une dysplasie corticale. A travers ce cas les auteurs mettent l’accent sur les lipomes intra-craniens avec quelques elements de diagnostic positif et differentiel. Dans les formes epileptogenes, la gestion medicale des osteolipomes est associee a un bon controle de la maladie epileptique. La chirurgie est indiquee dans les formes associees a des compressions des nerfs crâniens ou associees a une hydrocephalie obstructive. Mots cles: dysplasie corticale, epilepsie, IRM, osteolipome English Title: Bifocal epileptogenic osteolipoma associated with cortical dysplasia: a case report

European Journal of Radiology, Apr 1, 2001

Diffusion and perfusion MR imaging are now being used increasingly in neuro-vascular clinical app... more Diffusion and perfusion MR imaging are now being used increasingly in neuro-vascular clinical applications. While diffusion weighted magnetic resonance imaging exploits the translational mobility of water molecules to obtain information on the microscopic behaviour of the tissues (presence of macromolecules, presence and permeability of membranes, equilibrium intracellular-extracellular water,…), perfusion weighted imaging makes use of endogenous and exogenous tracers for monitoring their hemodynamic status. The combination of both techniques is extremely promising for the early detection and assessment of stroke, for tumor characterisation and for the evaluation of neurodegenerative diseases. This article provides a brief review of the basic physics principles underlying the methodologies followed.

JMV-Journal de Médecine Vasculaire, Dec 1, 2019

B. Alami et al. Conclusion.-L'IRM cérébrale est actuellement le meilleur moyen d'imagerie dans le... more B. Alami et al. Conclusion.-L'IRM cérébrale est actuellement le meilleur moyen d'imagerie dans le diagnostic de la TVC, permettant d'apprécier avec précision sa localisation, son étendue et le retentissement sur le parenchyme cérébral. De multiples affections sont responsables des TVC. La prise en charge thérapeutique repose sur l'héparinothérapie et le traitement étiologique.

Annals of Saudi Medicine, Sep 1, 2007

Annals of Neurosciences, 2017

a motor paradigm in block design. Results: The blood ionogram revealed hypercalcemia and hyponatr... more a motor paradigm in block design. Results: The blood ionogram revealed hypercalcemia and hyponatremia in both patients. Both biological assessment and BOLD-fMRI study results revealed a high level of OS that induced activation of a significantly large brain volume area suggesting the occurrence of possible brain plasticity and functional control reorganization induced by free radicals and enhanced by AD. Conclusion: The occurrence of brain plasticity and functional control reorganization was demonstrated in both patients studied who were undergoing HD by BOLD-fMRI with a notable sensitivity; this plasticity is induced by elevated OS occasioned by HD technique itself and probably amplified by AD. Similar results were found in a previous study performed on the same patients undergoing HD by a polysulfone membrane.

Médecine des Maladies Métaboliques, Feb 1, 2016

L'hémodialyse est l'alternative la plus répandue pour surmonter l'insuffisance rénale chronique t... more L'hémodialyse est l'alternative la plus répandue pour surmonter l'insuffisance rénale chronique terminale. Cependant, cette technique présente plusieurs effets indésirables, telles la production excessive des radicaux libres induisant un stress oxydant, et la production de facteurs inflammatoires impliqués dans la physiopathologie de certaines des complications à long terme. La maitrise du stress oxydant et de l'inflammation par l'utilisation de membranes davantage biocompatibles et par des stratégies de supplémentation nutritionnelle pourraient réduire le stress oxydatif et l'inflammation et, partant, améliorer le pronostic à long terme des patients hémodialysés.

Journal of Neurosciences in Rural Practice, Apr 26, 2023

Rabies is a viral infection with a high mortality rate. Typical symptoms of rabies include hydrop... more Rabies is a viral infection with a high mortality rate. Typical symptoms of rabies include hydrophobia, aerophobia, pharyngeal muscle spasms, and progressive paralysis. Psychiatric symptoms induced by rabies are not common. We report the case of a 26-year-old man in whom a quite typical clinical presentation of a brief psychotic disorder revealed rabies encephalitis.

International Journal of Molecular Sciences, Mar 28, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY