Sameer Ahmad - Academia.edu (original) (raw)
Papers by Sameer Ahmad
Acta Ophthalmologica, 2016
Investigative Ophthalmology & Visual Science, 2003
Saudi Journal of Ophthalmology, 2020
IntroductIon T he implantation of glaucoma drainage devices (GDD) has steadily increased over the... more IntroductIon T he implantation of glaucoma drainage devices (GDD) has steadily increased over the last several years especially in eyes with failed filtration surgery. [1-5] GDD implantation has also been performed as a primary intervention in cases with a high risk for failed trabeculectomy. [1-5] The tube versus trabeculectomy (TVT) study, has reported higher success rates with GDD than trabeculectomy. [1] A recent prospective comparison of the Ahmed valve to the Baerveldt implant reported good success with minor differences between the implants. [6] However, most studies of these GDD report a risk of corneal decompensation that ranges from 10-16%, which is much higher than that reported after conventional trabeculectomy. [1,7-9] The higher rate of corneal decompensation after GDD implantation has been attributed to a number of factors including, the decreased distance between the tube tip and endothelium and mechanical touch during eye rubbing or eye movement and blinking. [10,11] An increased risk of corneal decompensation has also been correlated to the length of the tube. However, a recent study used multivariate analysis to report that only the distance between the tube tip and endothelium was significantly associated with postoperative endothelial cell loss and tube length was not a factor. [2] Pars plana insertion of the tube has
Journal of American Association for Pediatric Ophthalmology and Strabismus, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Journal of Glaucoma, 2019
*Ahmad FP7 was taken as the reference category. †No patch graft used was used as the reference ca... more *Ahmad FP7 was taken as the reference category. †No patch graft used was used as the reference category. ‡Prolene was used as reference category. CAI indicates carbonic anhydrase inhibitor, CI, confidence interval; 5-FU, 5 fluorouracil; HR, hazard ratio; MMC, mtomycin C.
Clinical ophthalmology (Auckland, N.Z.), 2018
To evaluate the effectiveness of an educational video in increasing knowledge among glaucoma pati... more To evaluate the effectiveness of an educational video in increasing knowledge among glaucoma patients and to determine the factors that may influence a patient's level of knowledge. This was a pre-post intervention study on adult glaucoma patients attending the outpatient service at King Khaled Eye Specialist Hospital. The intervention tested was a short educational video that was edited specifically for this study. All patients completed a pre-video and post-video knowledge questionnaire; moreover, sociodemographic and clinical characteristics were obtained. The total number of patients included was 196. The mean age of patients was 55.7±15.5 years. Overall, 55.1% were males, 29.6% were illiterate, 85.2% resided in an urban area, 62.8% had a low income, and 41.8% were unemployed. The mean pre-intervention knowledge score was 6 out of 17, and the post-intervention score was 11.1 (≤0.001). Predictors of a poor knowledge score were old age (>60 years), female sex, illiteracy, r...
Investigative Ophthalmology Visual Science, 1995
Cornea, 1995
A number of studies, using either rat or rabbit models, have focused on delineating the role of c... more A number of studies, using either rat or rabbit models, have focused on delineating the role of cell surface glycoconjugates in corneal epithelial cell migration and wound healing. We have recently identified the cell surface sialoglycoproteins of rabbit corneal epithelium and have shown that the levels of at least three membrane glycoproteins are markedly altered during cell migration. Because species-related differences may be present, it is important to select an appropriate animal model for studies designed to contribute to the understanding of the mechanism of human corneal wound healing. The purpose of this study was to identify the cell surface sialoglycoproteins of human corneal epithelium. Plasma membrane sialoglycoproteins of primary cultures of human corneal epithelium were labeled with NaB3H4 after oxidation by mild NaIO4 treatment. The labeled glycoproteins were analyzed by SDS-polyacrylamide gel electrophoresis and fluorography. Four different preparations of human corneal epithelial cell cultures were analyzed, and results were compared with those of rabbit corneal epithelium. Of the 11 radiolabeled sialoglycoproteins we identified recently in rabbit corneal epithelium, eight were also present in human corneal epithelium. These similarities in the electrophoretic patterns of the plasma membrane glycoproteins of the two species suggest that rabbit is most likely an appropriate animal model for studies designed to contribute to the understanding of the structure and function of cell surface glycoproteins of human corneal epithelium.
Supplemental material, EJO-19-0385.R1_authorship_change_form for A preliminary comparison of the ... more Supplemental material, EJO-19-0385.R1_authorship_change_form for A preliminary comparison of the Aravind aurolab drainage implant with the Baerveldt glaucoma implant: A matched case-control study by Najla Hafeezullah, Sara AlHilali, Fahad Alghulaydhawi, Deepak P Edward, Sameer Ahmad and Rizwan Malik in European Journal of Ophthalmology
Current Eye …, 2011
Purpose: Long-term intraocular pressure reduction by glaucoma drainage devices (GDDs) is often li... more Purpose: Long-term intraocular pressure reduction by glaucoma drainage devices (GDDs) is often limited by the fibrotic capsule that forms around them. Prior work demonstrates that modifying a GDD with a porous membrane promotes a vascularized and more permeable capsule. ...
Ophthalmology, 2009
Objective: To describe the results of revision surgery for complications of trabeculectomy in a c... more Objective: To describe the results of revision surgery for complications of trabeculectomy in a case series from an academic glaucoma service.
American Journal of Surgery, 1995
BACKGROUND: Because the duration of postoperative ileus after uncomplicated colon surgery has inc... more BACKGROUND: Because the duration of postoperative ileus after uncomplicated colon surgery has increased at our institution in the past 4 years, thereby prolonging length of hospital stay for some patients, we assessed several clinical factors to determine which were responsible for the increase.
American Journal of Ophthalmology, 2004
In contrast, our patient developed choroidal detachments with the use of glaucoma therapy in a su... more In contrast, our patient developed choroidal detachments with the use of glaucoma therapy in a surgically untreated eye. The eye had not been "presensitized" by surgical intervention or underlying pathology. Nonetheless, the patient's long-term use of low-dose systemic hydrochlorothiazide, started 5 years previously, might have been a "sensitizing factor." This sulfa-containing drug was previously implicated in the development of choroidal effusions and angle-closure glaucoma. 5 Unlike in the described reports, however, our patient recovered by removal of the aqueous suppressants alone, and her hydrochlorothiazide was continued. Furthermore, there was no shallowing of the angles or change in refraction.
Current Eye Research, 2009
Acta Ophthalmologica, 2016
Investigative Ophthalmology & Visual Science, 2003
Saudi Journal of Ophthalmology, 2020
IntroductIon T he implantation of glaucoma drainage devices (GDD) has steadily increased over the... more IntroductIon T he implantation of glaucoma drainage devices (GDD) has steadily increased over the last several years especially in eyes with failed filtration surgery. [1-5] GDD implantation has also been performed as a primary intervention in cases with a high risk for failed trabeculectomy. [1-5] The tube versus trabeculectomy (TVT) study, has reported higher success rates with GDD than trabeculectomy. [1] A recent prospective comparison of the Ahmed valve to the Baerveldt implant reported good success with minor differences between the implants. [6] However, most studies of these GDD report a risk of corneal decompensation that ranges from 10-16%, which is much higher than that reported after conventional trabeculectomy. [1,7-9] The higher rate of corneal decompensation after GDD implantation has been attributed to a number of factors including, the decreased distance between the tube tip and endothelium and mechanical touch during eye rubbing or eye movement and blinking. [10,11] An increased risk of corneal decompensation has also been correlated to the length of the tube. However, a recent study used multivariate analysis to report that only the distance between the tube tip and endothelium was significantly associated with postoperative endothelial cell loss and tube length was not a factor. [2] Pars plana insertion of the tube has
Journal of American Association for Pediatric Ophthalmology and Strabismus, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Journal of Glaucoma, 2019
*Ahmad FP7 was taken as the reference category. †No patch graft used was used as the reference ca... more *Ahmad FP7 was taken as the reference category. †No patch graft used was used as the reference category. ‡Prolene was used as reference category. CAI indicates carbonic anhydrase inhibitor, CI, confidence interval; 5-FU, 5 fluorouracil; HR, hazard ratio; MMC, mtomycin C.
Clinical ophthalmology (Auckland, N.Z.), 2018
To evaluate the effectiveness of an educational video in increasing knowledge among glaucoma pati... more To evaluate the effectiveness of an educational video in increasing knowledge among glaucoma patients and to determine the factors that may influence a patient's level of knowledge. This was a pre-post intervention study on adult glaucoma patients attending the outpatient service at King Khaled Eye Specialist Hospital. The intervention tested was a short educational video that was edited specifically for this study. All patients completed a pre-video and post-video knowledge questionnaire; moreover, sociodemographic and clinical characteristics were obtained. The total number of patients included was 196. The mean age of patients was 55.7±15.5 years. Overall, 55.1% were males, 29.6% were illiterate, 85.2% resided in an urban area, 62.8% had a low income, and 41.8% were unemployed. The mean pre-intervention knowledge score was 6 out of 17, and the post-intervention score was 11.1 (≤0.001). Predictors of a poor knowledge score were old age (>60 years), female sex, illiteracy, r...
Investigative Ophthalmology Visual Science, 1995
Cornea, 1995
A number of studies, using either rat or rabbit models, have focused on delineating the role of c... more A number of studies, using either rat or rabbit models, have focused on delineating the role of cell surface glycoconjugates in corneal epithelial cell migration and wound healing. We have recently identified the cell surface sialoglycoproteins of rabbit corneal epithelium and have shown that the levels of at least three membrane glycoproteins are markedly altered during cell migration. Because species-related differences may be present, it is important to select an appropriate animal model for studies designed to contribute to the understanding of the mechanism of human corneal wound healing. The purpose of this study was to identify the cell surface sialoglycoproteins of human corneal epithelium. Plasma membrane sialoglycoproteins of primary cultures of human corneal epithelium were labeled with NaB3H4 after oxidation by mild NaIO4 treatment. The labeled glycoproteins were analyzed by SDS-polyacrylamide gel electrophoresis and fluorography. Four different preparations of human corneal epithelial cell cultures were analyzed, and results were compared with those of rabbit corneal epithelium. Of the 11 radiolabeled sialoglycoproteins we identified recently in rabbit corneal epithelium, eight were also present in human corneal epithelium. These similarities in the electrophoretic patterns of the plasma membrane glycoproteins of the two species suggest that rabbit is most likely an appropriate animal model for studies designed to contribute to the understanding of the structure and function of cell surface glycoproteins of human corneal epithelium.
Supplemental material, EJO-19-0385.R1_authorship_change_form for A preliminary comparison of the ... more Supplemental material, EJO-19-0385.R1_authorship_change_form for A preliminary comparison of the Aravind aurolab drainage implant with the Baerveldt glaucoma implant: A matched case-control study by Najla Hafeezullah, Sara AlHilali, Fahad Alghulaydhawi, Deepak P Edward, Sameer Ahmad and Rizwan Malik in European Journal of Ophthalmology
Current Eye …, 2011
Purpose: Long-term intraocular pressure reduction by glaucoma drainage devices (GDDs) is often li... more Purpose: Long-term intraocular pressure reduction by glaucoma drainage devices (GDDs) is often limited by the fibrotic capsule that forms around them. Prior work demonstrates that modifying a GDD with a porous membrane promotes a vascularized and more permeable capsule. ...
Ophthalmology, 2009
Objective: To describe the results of revision surgery for complications of trabeculectomy in a c... more Objective: To describe the results of revision surgery for complications of trabeculectomy in a case series from an academic glaucoma service.
American Journal of Surgery, 1995
BACKGROUND: Because the duration of postoperative ileus after uncomplicated colon surgery has inc... more BACKGROUND: Because the duration of postoperative ileus after uncomplicated colon surgery has increased at our institution in the past 4 years, thereby prolonging length of hospital stay for some patients, we assessed several clinical factors to determine which were responsible for the increase.
American Journal of Ophthalmology, 2004
In contrast, our patient developed choroidal detachments with the use of glaucoma therapy in a su... more In contrast, our patient developed choroidal detachments with the use of glaucoma therapy in a surgically untreated eye. The eye had not been "presensitized" by surgical intervention or underlying pathology. Nonetheless, the patient's long-term use of low-dose systemic hydrochlorothiazide, started 5 years previously, might have been a "sensitizing factor." This sulfa-containing drug was previously implicated in the development of choroidal effusions and angle-closure glaucoma. 5 Unlike in the described reports, however, our patient recovered by removal of the aqueous suppressants alone, and her hydrochlorothiazide was continued. Furthermore, there was no shallowing of the angles or change in refraction.
Current Eye Research, 2009