Samuel Willson - Academia.edu (original) (raw)
Papers by Samuel Willson
Reading and Writing, 2006
This study explored third-graders’ oral reading fluency (ORF) in easy text in relation to their t... more This study explored third-graders’ oral reading fluency (ORF) in easy text in relation to their third- and fourth-grade reading comprehension. It also examined the children’s performance on two different measures of text exposure, a self-report questionnaire and a title-recognition test. Although third-graders’ ORF related significantly to their reading comprehension, oral language comprehension accounted for most of the variance in reading comprehension, whereas single word reading speed accounted for most of the variance in ORF. Third-grade reading comprehension and ORF each predicted unique variance in children’s scores on a fourth-grade state-mandated reading comprehension assessment. Scores on the self-report questionnaire correlated significantly with third-grade ORF and fourth-grade reading; the self-report accounted for reliable variance in ORF even with all of the other reading ability variables entered first. Results are consistent with the viewpoint that text exposure affects reading fluency. They also demonstrate that ORF is a valuable predictor of middle-elementary children’s reading comprehension, even when the ORF measure employs very easy text in which children achieve near-perfect word accuracy.
Multivariate Behavioral Research, 2007
This Monte Carlo study examined the impact of misspecifying the Σ matrix in longitudinal data ana... more This Monte Carlo study examined the impact of misspecifying the Σ matrix in longitudinal data analysis under both the multilevel model and mixed model frameworks. Under the multilevel model approach, under-specification and general-misspecification of the Σ matrix usually resulted in overestimation of the variances of the random effects (e.g., τ00, ττ11) and standard errors of the corresponding growth parameter estimates (e.g., SEβ 0, SEβ 1). Overestimates of the standard errors led to lower statistical power in tests of the growth parameters. An unstructured Σ matrix under the mixed model framework generally led to underestimates of standard errors of the growth parameter estimates. Underestimates of the standard errors led to inflation of the type I error rate in tests of the growth parameters. Implications of the compensatory relationship between the random effects of the growth parameters and the longitudinal error structure for model specification were discussed.
Journal of Marriage and The Family, 2005
Scientific Studies of Reading, 2006
Parasitology Research, 2005
Eleven controlled studies were conducted in the United States and Europe to evaluate the efficacy... more Eleven controlled studies were conducted in the United States and Europe to evaluate the efficacy of a topical solution of emodepside (3 mg/kg)+praziquantel (12 mg/kg) (Profender®, Bayer AG, Leverkusen, Germany) against infection with various stages of the ascarid nematodes Toxocara cati and Toxascaris leonina. Infections were induced by administration of larvated ascarid eggs, and stage–specific efficacy was evaluated by treating cats at scheduled intervals post–inoculation. All studies featured random allocation to treatment groups, placebo–treated control animals and assessment of outcome measures by masked personnel. The product (emodepside+praziquantel topical solution) was 100% effective against mature adults and immature adult T. cati. In addition, it was 96.8% effective against third stage larvae and at least 99.4% effective against fourth stage larvae of T. cati, respectively. Efficacy against mature, immature adult and L4 stages of T. leonina exceeded 93.4%, but regulatory “adequacy of infection” criteria were not met in sorne studies. No adverse reactions to treatment were noted in cats treated with the emodepside+praziquantel topical solution.
British Journal of Surgery, 1997
Journal of Laryngology and Otology, 1996
Pharyngolaryngoesophagectomy (PLO) for post-cricoid tumour offers opportunity for cure or reasona... more Pharyngolaryngoesophagectomy (PLO) for post-cricoid tumour offers opportunity for cure or reasonable paliation. However, it carries significant morbidity and mortality. We present two patients with post-cricoid carcinomas who underwent laparoscopically-assisted total PLO with gastric transposition without a laparotomy, thoracotomy or thoracoscopy. This technique appears promising for patients with post-cricoid or hypopharyngeal malignancy in reducing operative morbidity, and may represent improvement on conventional open and thoracoscopic techniques in selected patients.
Parasitology Research, 2005
This paper reports the efficacy of emodepside/praziquantel spot–on (Profender®, Bayer AG, Leverku... more This paper reports the efficacy of emodepside/praziquantel spot–on (Profender®, Bayer AG, Leverkusen, Germany), a novel broadspectrum anthelmintic for dermal application, against L4 larvae and immature adult and adult stages of Ancylostoma tubaeforme in cats. The formulation contains 2.14% (w/w) emodepside and 8.58% (w/v) praziquantel, with emodepside being active against gastrointestinal nematodes and praziquantel against cestodes. Five randomized, blinded and controlled laboratory studies demonstrated 100% efficacy of emodepside/praziquantel spot–on against mature A. tubaeforme and an efficacy of >95% and >97%, respectively, against L4 larvae and immature adults (based on worm counts after necropsy) at approximately the minimum proposed dose rate in cats of 3.0 mg emodepside and 12.0 mg praziquantel/kg body weight. No adverse reactions to the treatment were observed. It is concluded that emodepside/praziquantel spot–on is an effective and safe treatment against infections with mature and immature A. tubaeforme. Emodepside/praziquantel spot–on will considerably facilitate the treatment of cats against nematodes and cestodes compared with orally administered preparations.
Reading and Writing, 2006
This study explored third-graders’ oral reading fluency (ORF) in easy text in relation to their t... more This study explored third-graders’ oral reading fluency (ORF) in easy text in relation to their third- and fourth-grade reading comprehension. It also examined the children’s performance on two different measures of text exposure, a self-report questionnaire and a title-recognition test. Although third-graders’ ORF related significantly to their reading comprehension, oral language comprehension accounted for most of the variance in reading comprehension, whereas single word reading speed accounted for most of the variance in ORF. Third-grade reading comprehension and ORF each predicted unique variance in children’s scores on a fourth-grade state-mandated reading comprehension assessment. Scores on the self-report questionnaire correlated significantly with third-grade ORF and fourth-grade reading; the self-report accounted for reliable variance in ORF even with all of the other reading ability variables entered first. Results are consistent with the viewpoint that text exposure affects reading fluency. They also demonstrate that ORF is a valuable predictor of middle-elementary children’s reading comprehension, even when the ORF measure employs very easy text in which children achieve near-perfect word accuracy.
Multivariate Behavioral Research, 2007
This Monte Carlo study examined the impact of misspecifying the Σ matrix in longitudinal data ana... more This Monte Carlo study examined the impact of misspecifying the Σ matrix in longitudinal data analysis under both the multilevel model and mixed model frameworks. Under the multilevel model approach, under-specification and general-misspecification of the Σ matrix usually resulted in overestimation of the variances of the random effects (e.g., τ00, ττ11) and standard errors of the corresponding growth parameter estimates (e.g., SEβ 0, SEβ 1). Overestimates of the standard errors led to lower statistical power in tests of the growth parameters. An unstructured Σ matrix under the mixed model framework generally led to underestimates of standard errors of the growth parameter estimates. Underestimates of the standard errors led to inflation of the type I error rate in tests of the growth parameters. Implications of the compensatory relationship between the random effects of the growth parameters and the longitudinal error structure for model specification were discussed.
Journal of Marriage and The Family, 2005
Scientific Studies of Reading, 2006
Parasitology Research, 2005
Eleven controlled studies were conducted in the United States and Europe to evaluate the efficacy... more Eleven controlled studies were conducted in the United States and Europe to evaluate the efficacy of a topical solution of emodepside (3 mg/kg)+praziquantel (12 mg/kg) (Profender®, Bayer AG, Leverkusen, Germany) against infection with various stages of the ascarid nematodes Toxocara cati and Toxascaris leonina. Infections were induced by administration of larvated ascarid eggs, and stage–specific efficacy was evaluated by treating cats at scheduled intervals post–inoculation. All studies featured random allocation to treatment groups, placebo–treated control animals and assessment of outcome measures by masked personnel. The product (emodepside+praziquantel topical solution) was 100% effective against mature adults and immature adult T. cati. In addition, it was 96.8% effective against third stage larvae and at least 99.4% effective against fourth stage larvae of T. cati, respectively. Efficacy against mature, immature adult and L4 stages of T. leonina exceeded 93.4%, but regulatory “adequacy of infection” criteria were not met in sorne studies. No adverse reactions to treatment were noted in cats treated with the emodepside+praziquantel topical solution.
British Journal of Surgery, 1997
Journal of Laryngology and Otology, 1996
Pharyngolaryngoesophagectomy (PLO) for post-cricoid tumour offers opportunity for cure or reasona... more Pharyngolaryngoesophagectomy (PLO) for post-cricoid tumour offers opportunity for cure or reasonable paliation. However, it carries significant morbidity and mortality. We present two patients with post-cricoid carcinomas who underwent laparoscopically-assisted total PLO with gastric transposition without a laparotomy, thoracotomy or thoracoscopy. This technique appears promising for patients with post-cricoid or hypopharyngeal malignancy in reducing operative morbidity, and may represent improvement on conventional open and thoracoscopic techniques in selected patients.
Parasitology Research, 2005
This paper reports the efficacy of emodepside/praziquantel spot–on (Profender®, Bayer AG, Leverku... more This paper reports the efficacy of emodepside/praziquantel spot–on (Profender®, Bayer AG, Leverkusen, Germany), a novel broadspectrum anthelmintic for dermal application, against L4 larvae and immature adult and adult stages of Ancylostoma tubaeforme in cats. The formulation contains 2.14% (w/w) emodepside and 8.58% (w/v) praziquantel, with emodepside being active against gastrointestinal nematodes and praziquantel against cestodes. Five randomized, blinded and controlled laboratory studies demonstrated 100% efficacy of emodepside/praziquantel spot–on against mature A. tubaeforme and an efficacy of >95% and >97%, respectively, against L4 larvae and immature adults (based on worm counts after necropsy) at approximately the minimum proposed dose rate in cats of 3.0 mg emodepside and 12.0 mg praziquantel/kg body weight. No adverse reactions to the treatment were observed. It is concluded that emodepside/praziquantel spot–on is an effective and safe treatment against infections with mature and immature A. tubaeforme. Emodepside/praziquantel spot–on will considerably facilitate the treatment of cats against nematodes and cestodes compared with orally administered preparations.