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Papers by Sara Garcia

Research paper thumbnail of Prevalence of urinary tract infection in infants with high fever in the emergency department

Anales de Pediatría (English Edition), 2019

Introduction: There is no current data on the prevalence of urinary tract infection (UTI) in infa... more Introduction: There is no current data on the prevalence of urinary tract infection (UTI) in infants and toddlers with high fever. We conducted this study to assess the point prevalence of UTI in children aged less than 2 years presenting with high fever to the emergency department. Methods: We conducted a prospective, multicentre, observational study including febrile children aged less than 2 years in whom urinalysis was performed to rule out UTI over a 1-year period in seven paediatric emergency departments in Spain. Boys younger than 1 year and girls younger than 2 years of age were eligible for the study if they had a rectal temperature greater than 39 • C, were not taking antibiotics, and there was no identifiable source of fever. The diagnosis of UTI was based on the presence of leukocyturia and positive urine culture results. Results: We included a total of 1675 patients. Tw o hundred sixty infants (15.5%; 95% CI, 13.8-17.3%) received a diagnosis of UTI. The point prevalence of UTI was 32.9% (95% CI, 26.6-39.9%) in febrile boys aged less than 6 months and 19.3% (95% CI, 16.1-22.9%) in febrile girls aged less than 12 months. The point prevalence of UTI was 13% (95%

Research paper thumbnail of The Validity of the Pediatric Assessment Triangle as the First Step in the Triage Process in a Pediatric Emergency Department

Pediatric emergency care, Jan 12, 2016

This study aimed to assess the association between pediatric assessment triangle (PAT) findings d... more This study aimed to assess the association between pediatric assessment triangle (PAT) findings during triage and markers of severity in a pediatric emergency department (PED). During the study period, patients arriving to the PED were classified by trained nurses with the Pediatric Canadian Triage and Acuity Scale using a computer system, from which data were obtained and analyzed retrospectively. The primary outcome measure was the percentage of children hospitalized related with PAT findings. The secondary outcome measures were the admission to the intensive care unit (%), PED length of stay, and performance of blood tests (%). Among the 302,103 episodes included, there were abnormal PAT findings in 24,120 cases (7.9%). Multivariate analysis adjusted for age confirmed that PAT findings and triage level were independent risk factors for admission (odds ratio [OR], 2.21; 95% confidence interval [CI], 2.13-2.29; OR, 6.01; 95% CI, 5.79-6.24, respectively). Abnormal findings in appear...

Research paper thumbnail of Intrazeolite Photochemistry. 14. Photochemistry of α,ω-Diphenyl Allyl Cations within Zeolites

The Journal of Physical Chemistry, 1996

1,3-Diphenylpropenylium (DP3 +) and 1,5-diphenylpentadienylium (DP5 +) ions have been generated w... more 1,3-Diphenylpropenylium (DP3 +) and 1,5-diphenylpentadienylium (DP5 +) ions have been generated within acid ZSM-5 and mordenite zeolites as persistent species by adsorption of R,ω-disubstituted R,ωdiphenylalkanes. It was found that besides R,ω-diacetates, R,ω-dichlorides and R,ω-diols are also convenient precursors. Irradiation of these allylic cations embedded within zeolites led to cis-trans isomerization as the only observable process. Molecular modeling suggests that there is enough space in the intersection of the channels in HZSM-5 to accommodate both the planar E,E-DP3 + and the nonplanar E,Z-DP3 + stereoisomers. Fluorescence emissions follow a near-first-order decay, with a dominant short and a minor long component; the latter having a lifetime close to that reported for DP5 + in solution at low temperatures. Z-E isomerization led to a blue-shift in the absorption spectra together with an increase in the apparent extinction coefficient, while emission maxima also appeared at longer wavelengths exhibiting distinctive decays. Evidence for the triplet excited states has been obtained by time-resolved diffuse reflectance spectroscopy. Estimated lifetimes obtained from the best first-order fit are in the tens of microseconds range. Weak delayed emission associated to the triplet excited state has also been observed.

Research paper thumbnail of Intrazeolite Photochemistry. 24. Enantioselective Discrimination in the Quenching of Chiral Mn(II)salen Complexes Encapsulated inside Y Zeolite by Chiral 2-Butanols

Journal of the American Chemical Society, 1998

Research paper thumbnail of Prevalence of urinary tract infection in infants with high fever in the emergency department

Anales de Pediatría (English Edition), 2019

Introduction: There is no current data on the prevalence of urinary tract infection (UTI) in infa... more Introduction: There is no current data on the prevalence of urinary tract infection (UTI) in infants and toddlers with high fever. We conducted this study to assess the point prevalence of UTI in children aged less than 2 years presenting with high fever to the emergency department. Methods: We conducted a prospective, multicentre, observational study including febrile children aged less than 2 years in whom urinalysis was performed to rule out UTI over a 1-year period in seven paediatric emergency departments in Spain. Boys younger than 1 year and girls younger than 2 years of age were eligible for the study if they had a rectal temperature greater than 39 • C, were not taking antibiotics, and there was no identifiable source of fever. The diagnosis of UTI was based on the presence of leukocyturia and positive urine culture results. Results: We included a total of 1675 patients. Tw o hundred sixty infants (15.5%; 95% CI, 13.8-17.3%) received a diagnosis of UTI. The point prevalence of UTI was 32.9% (95% CI, 26.6-39.9%) in febrile boys aged less than 6 months and 19.3% (95% CI, 16.1-22.9%) in febrile girls aged less than 12 months. The point prevalence of UTI was 13% (95%

Research paper thumbnail of The Validity of the Pediatric Assessment Triangle as the First Step in the Triage Process in a Pediatric Emergency Department

Pediatric emergency care, Jan 12, 2016

This study aimed to assess the association between pediatric assessment triangle (PAT) findings d... more This study aimed to assess the association between pediatric assessment triangle (PAT) findings during triage and markers of severity in a pediatric emergency department (PED). During the study period, patients arriving to the PED were classified by trained nurses with the Pediatric Canadian Triage and Acuity Scale using a computer system, from which data were obtained and analyzed retrospectively. The primary outcome measure was the percentage of children hospitalized related with PAT findings. The secondary outcome measures were the admission to the intensive care unit (%), PED length of stay, and performance of blood tests (%). Among the 302,103 episodes included, there were abnormal PAT findings in 24,120 cases (7.9%). Multivariate analysis adjusted for age confirmed that PAT findings and triage level were independent risk factors for admission (odds ratio [OR], 2.21; 95% confidence interval [CI], 2.13-2.29; OR, 6.01; 95% CI, 5.79-6.24, respectively). Abnormal findings in appear...

Research paper thumbnail of Intrazeolite Photochemistry. 14. Photochemistry of α,ω-Diphenyl Allyl Cations within Zeolites

The Journal of Physical Chemistry, 1996

1,3-Diphenylpropenylium (DP3 +) and 1,5-diphenylpentadienylium (DP5 +) ions have been generated w... more 1,3-Diphenylpropenylium (DP3 +) and 1,5-diphenylpentadienylium (DP5 +) ions have been generated within acid ZSM-5 and mordenite zeolites as persistent species by adsorption of R,ω-disubstituted R,ωdiphenylalkanes. It was found that besides R,ω-diacetates, R,ω-dichlorides and R,ω-diols are also convenient precursors. Irradiation of these allylic cations embedded within zeolites led to cis-trans isomerization as the only observable process. Molecular modeling suggests that there is enough space in the intersection of the channels in HZSM-5 to accommodate both the planar E,E-DP3 + and the nonplanar E,Z-DP3 + stereoisomers. Fluorescence emissions follow a near-first-order decay, with a dominant short and a minor long component; the latter having a lifetime close to that reported for DP5 + in solution at low temperatures. Z-E isomerization led to a blue-shift in the absorption spectra together with an increase in the apparent extinction coefficient, while emission maxima also appeared at longer wavelengths exhibiting distinctive decays. Evidence for the triplet excited states has been obtained by time-resolved diffuse reflectance spectroscopy. Estimated lifetimes obtained from the best first-order fit are in the tens of microseconds range. Weak delayed emission associated to the triplet excited state has also been observed.

Research paper thumbnail of Intrazeolite Photochemistry. 24. Enantioselective Discrimination in the Quenching of Chiral Mn(II)salen Complexes Encapsulated inside Y Zeolite by Chiral 2-Butanols

Journal of the American Chemical Society, 1998