Sara Khan - Academia.edu (original) (raw)
Papers by Sara Khan
Ceskoslovenske zdravotnictvi, 1966
Neuroepidemiology, 2020
Background: Hereditary neuromuscular disorders (NMDs) result in progressive disability with no de... more Background: Hereditary neuromuscular disorders (NMDs) result in progressive disability with no definitive disease modifying treatments. There is a delay in diagnosis, and lack of awareness among affected individuals about these disorders, which can affect quality of life of patients. Objective: The aim of this study is to identify gaps in patient knowledge, factors affecting attitudes toward the diagnoses, and specific practices to create better awareness among patients and healthcare providers to improve care and overall outcomes. Methods: This is a cross-sectional study of 130 patients diagnosed with an NMD, recruited from the outpatient neurology clinics at the Aga Khan University Hospital. After telephonic consent, a 28 item survey questionnaire was administered. Knowledge, attitude, and practice scores were measured. Results: One hundred and thirty of 198 study participants responded. The average age was 26.3 years; 75% were male. More than 38% (n = 50) had a middle grade or le...
Motifs : An International Journal of English Studies, 2016
In the recent times, literature has witnessed the rising of a very different and vague genre call... more In the recent times, literature has witnessed the rising of a very different and vague genre called Erotic Literature. Though there have been traces of such works since the emergence of novel, for example, John Cleland's Memoirs of a Woman of Pleasure (1748) or more popularly known as Fanny Hill, in 1791, Marquis de Sade (French) published Justine or Misfortunes of Virtue and in 1869 Leopold von Sacher-Masoch published his infamous novella Venus in Furs and so on . Later in the nineteenth century, psychology developed as a concrete science and the intricacies of the human mind were meticulously deciphered. The implications of this new science were largely visible in the world of literature and Psychoanalysis became one of the major sources of interpretation of text and striking connections were unveiled. One of the most recent pieces of work that certainly created a ripple in the contemporary literature of the world is the trilogy of Fifty Shades of Grey by E.L James which became an enduring structure in bondage, discipline, dominance, sadism, submission and masochism (BDSM) fiction and romance. In this intriguing novel, the protagonist Christian Grey is a young entrepreneur who is interviewed by Anastasia Steele, the female protagonist, as the novel proceeds a relationship blooms between the two which eventually lead to the unravelling of the 50 shades of Christian Grey. Grey turns out to be a sadist and Ana his new found girl. His peculiarities in performing the sexual activities and his perfection at BDSM compelled some of the critics and psychoanalysts to diagnose him with a mental disorder that is sexual sadism. Similarly, Karl Jabag claims to find symptoms of post-traumatic stress due to his disturbing past. His unnatural obsession with sadistic action convey the character's relation with terms like oedipal complex, denial, sublimation, internal conflicts, pleasure principal and so on, and thus making him a dear character to do a case study on for psychoanalysts by profession or by passion.
Southern African Linguistics and Applied Language Studies, 2009
Media theorists such as Barnett (2002), Buckingham (1997 & 2000) and Sampson (199... more Media theorists such as Barnett (2002), Buckingham (1997 & 2000) and Sampson (1999) describe a perceived crisis hindering the media's ability to inform citizens for participation in democracy. One of the symptoms and causes of this crisis, they argue, is that the media use language that many citizens cannot understand. This article draws on theories and methodologies from linguistics to
Benzene found all over our environment and are toxic to general population especially children. T... more Benzene found all over our environment and are toxic to general population especially children. This aromatic hydrocarbon being used in making of rubbers, lubricants, drugs, dyes and used as intermediate to make other chemicals and thus cause occupational hazard. Studies were carried out exposing the adult Wistar rats of 175-200gm to benzene (800mg/ kg body weight) via gavaging in corn oil for a period of 30 days and control rats received only vehicle for same period. The aim of the present work was to study the effect of benzene on the enzyme of carbohydrate metabolism, BBM and antioxidant defense parameters in different rat tissues. The nephrotoxic effect of benzene was manifested by increase blood urea nitrogen, serum creatinine and cholesterol levels. The activity of lactate dehydrogenase (LDH) increases whereas malate dehydrogenase (MDH) was decreased by benzene. The biomarker of brush border membrane alkaline phosphatase, gamma-glutamyl tranferase and leucine amino peptidase decreased in BBM of rat tissues. The activity of gluconeogenic enzymes G6Pase and FBPase declined by benzene exposure. In addition, the activities of superoxide dismutase and catalase significantly decrease with associated increase in lipid peroxidation. The results indicate that benzene induced nephrotoxicity and lowered the enzymes of carbohydrate metabolism and BBM most likely by inducing oxidative stress.
rapport nr.: Doctoral Dissertation 180, 2006
Ceskoslovenske zdravotnictvi, 1966
Neuroepidemiology, 2020
Background: Hereditary neuromuscular disorders (NMDs) result in progressive disability with no de... more Background: Hereditary neuromuscular disorders (NMDs) result in progressive disability with no definitive disease modifying treatments. There is a delay in diagnosis, and lack of awareness among affected individuals about these disorders, which can affect quality of life of patients. Objective: The aim of this study is to identify gaps in patient knowledge, factors affecting attitudes toward the diagnoses, and specific practices to create better awareness among patients and healthcare providers to improve care and overall outcomes. Methods: This is a cross-sectional study of 130 patients diagnosed with an NMD, recruited from the outpatient neurology clinics at the Aga Khan University Hospital. After telephonic consent, a 28 item survey questionnaire was administered. Knowledge, attitude, and practice scores were measured. Results: One hundred and thirty of 198 study participants responded. The average age was 26.3 years; 75% were male. More than 38% (n = 50) had a middle grade or le...
Motifs : An International Journal of English Studies, 2016
In the recent times, literature has witnessed the rising of a very different and vague genre call... more In the recent times, literature has witnessed the rising of a very different and vague genre called Erotic Literature. Though there have been traces of such works since the emergence of novel, for example, John Cleland's Memoirs of a Woman of Pleasure (1748) or more popularly known as Fanny Hill, in 1791, Marquis de Sade (French) published Justine or Misfortunes of Virtue and in 1869 Leopold von Sacher-Masoch published his infamous novella Venus in Furs and so on . Later in the nineteenth century, psychology developed as a concrete science and the intricacies of the human mind were meticulously deciphered. The implications of this new science were largely visible in the world of literature and Psychoanalysis became one of the major sources of interpretation of text and striking connections were unveiled. One of the most recent pieces of work that certainly created a ripple in the contemporary literature of the world is the trilogy of Fifty Shades of Grey by E.L James which became an enduring structure in bondage, discipline, dominance, sadism, submission and masochism (BDSM) fiction and romance. In this intriguing novel, the protagonist Christian Grey is a young entrepreneur who is interviewed by Anastasia Steele, the female protagonist, as the novel proceeds a relationship blooms between the two which eventually lead to the unravelling of the 50 shades of Christian Grey. Grey turns out to be a sadist and Ana his new found girl. His peculiarities in performing the sexual activities and his perfection at BDSM compelled some of the critics and psychoanalysts to diagnose him with a mental disorder that is sexual sadism. Similarly, Karl Jabag claims to find symptoms of post-traumatic stress due to his disturbing past. His unnatural obsession with sadistic action convey the character's relation with terms like oedipal complex, denial, sublimation, internal conflicts, pleasure principal and so on, and thus making him a dear character to do a case study on for psychoanalysts by profession or by passion.
Southern African Linguistics and Applied Language Studies, 2009
Media theorists such as Barnett (2002), Buckingham (1997 & 2000) and Sampson (199... more Media theorists such as Barnett (2002), Buckingham (1997 & 2000) and Sampson (1999) describe a perceived crisis hindering the media's ability to inform citizens for participation in democracy. One of the symptoms and causes of this crisis, they argue, is that the media use language that many citizens cannot understand. This article draws on theories and methodologies from linguistics to
Benzene found all over our environment and are toxic to general population especially children. T... more Benzene found all over our environment and are toxic to general population especially children. This aromatic hydrocarbon being used in making of rubbers, lubricants, drugs, dyes and used as intermediate to make other chemicals and thus cause occupational hazard. Studies were carried out exposing the adult Wistar rats of 175-200gm to benzene (800mg/ kg body weight) via gavaging in corn oil for a period of 30 days and control rats received only vehicle for same period. The aim of the present work was to study the effect of benzene on the enzyme of carbohydrate metabolism, BBM and antioxidant defense parameters in different rat tissues. The nephrotoxic effect of benzene was manifested by increase blood urea nitrogen, serum creatinine and cholesterol levels. The activity of lactate dehydrogenase (LDH) increases whereas malate dehydrogenase (MDH) was decreased by benzene. The biomarker of brush border membrane alkaline phosphatase, gamma-glutamyl tranferase and leucine amino peptidase decreased in BBM of rat tissues. The activity of gluconeogenic enzymes G6Pase and FBPase declined by benzene exposure. In addition, the activities of superoxide dismutase and catalase significantly decrease with associated increase in lipid peroxidation. The results indicate that benzene induced nephrotoxicity and lowered the enzymes of carbohydrate metabolism and BBM most likely by inducing oxidative stress.
rapport nr.: Doctoral Dissertation 180, 2006