Sarah Maling - Academia.edu (original) (raw)
Papers by Sarah Maling
The Lancet Child & Adolescent Health, 2021
Research Square (Research Square), Dec 5, 2023
Ophthalmology, 2008
To compare the binocular near vision performance in patients implanted with the 1CU accommodating... more To compare the binocular near vision performance in patients implanted with the 1CU accommodating intraocular lens (IOL) with a multifocal and monofocal IOL. Design: Prospective, randomized, double-masked clinical trial. Participants: Ninety patients presenting for cataract surgery to the Department of Ophthalmology, Hillingdon Hospital were randomized to receive the 1CU accommodative IOL, a multifocal IOL, or a monofocal IOL (control group). Methods: Patients underwent bilateral sequential phacoemulsification with implantation of 1 of the 3 IOL types and were assessed at 3 and 18 months after second-eye surgery. Main Outcome Measures: Logarithm of the minimum angle of resolution distance and near visual acuities (VAs) (unaided and distance corrected), contrast sensitivity, and accommodative amplitude (near point and defocusing) were measured at 3 and 18 months. Reading speed was assessed at 18 months, and glare symptoms and spectacle independence were compared using a standardized questionnaire. Results: Mean unaided and distance-corrected binocular near VAs were similar in the 1CU and multifocal and were significantly higher than the control group's (PϽ0.02). There was no significant difference in reading speed between any of the groups, but critical print sizes were similar in the 1CU and multifocal groups and significantly better than the control group's (P ϭ 0.02). The accommodative range was highest in the multifocal group and lowest in the control group, and there was no significant difference between the 1CU and control groups for defocus or near point at 18 months. Of the 1CU group and control group, 71.4% and 63.2%, respectively, experienced no glare at 18 months, compared with only 25% of the multifocal group (P ϭ 0.01). Of the 1CU group and multifocal group, 19% and 27.3%, respectively, were completely spectacle independent at 18 months; none of the control group was (P ϭ 0.05). Conclusions: The 1CU accommodating IOL provides improved near vision compared with a monofocal IOL. There is a discrepancy between the near function and accommodative amplitude measured in the 1CU. The multifocal provides excellent near acuity, but photopic phenomena remain a problem inherent in the lens design.
Investigative Ophthalmology & Visual Science, Apr 17, 2010
Sclerotherapy treatment of orbital lymphatic malformations: a large single-centre experience
Eye, 2022
Spontaneous, non-traumatic paediatric vitreous haemorrhage may occur secondary to a persistent hy... more Spontaneous, non-traumatic paediatric vitreous haemorrhage may occur secondary to a persistent hyaloid artery, which is easily diagnosed if visible on fundoscopy. We present two cases of unexplained paediatric vitreous haemorrhage, referred to our tertiary clinic, in which optical coherence tomography angiography (OCT-A) was used to demonstrate flow through otherwise clinically occult, hyaloid and peripapillary arterial remnants. OCT-A may prevent the need for extensive investigations in some cases paediatric vitreous haemorrhage, previously classified as idiopathic.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2011
Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggress... more Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggressive biological behaviour in the paediatric population. Complete surgical excision, where possible, is the ideal. This case report discusses the multidisciplinary, surgical management of two complex cases of large juvenile ossifying fibroma (JOF), involving the orbit. Both patients underwent resection of the orbital ossifying fibroma with no macroscopic evidence of recurrence at 4 years follow-up. Full functional outcome was achieved with preservation of vision and facial nerve function as well as good facial symmetry and aesthetics. The successful surgical outcome of these cases was due to a combination of a multidisciplinary team approach, rigorous pre-operative planning, maximal tumour resection, and the use of a novel surgical technique involving a medial zygomatic-orbito-maxillary rotational osteotomy.
The British journal of ophthalmology, Jan 17, 2015
Percutaneous sclerotherapy is an alternative to surgery for the treatment of orbital lymphatic ma... more Percutaneous sclerotherapy is an alternative to surgery for the treatment of orbital lymphatic malformations (LMs). We present a large series of patients undergoing sclerotherapy for macrocystic LMs with detailed visual acuity (VA) outcome data. Data were collected prospectively in all patients with macrocystic orbital LMs undergoing sclerotherapy. Sclerotherapy was performed under general anaesthesia, instilling sodium tetradecyl sulfate under imaging control. Procedures were repeated at 2-week to 6-week intervals, depending on clinical response. Patients underwent ophthalmological assessment, ultrasound and/or MRI before and after treatment. change in maximal radiological diameter of the LM. Secondary outcome measure: change in VA after treatment. 29 patients underwent 71 procedures (1-8 procedures per patient) over 6.7 years. Mean age=7.31 years. 11 patients (37.9%) had undergone previous treatment, including excision biopsy, drainage and decompression. All patients presented wit...
Medical teacher, Jan 10, 2015
Journal of Plastic, Reconstructive & Aesthetic Surgery, 2011
Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggress... more Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggressive biological behaviour in the paediatric population. Complete surgical excision, where possible, is the ideal. This case report discusses the multidisciplinary, surgical management of two complex cases of large juvenile ossifying fibroma (JOF), involving the orbit. Both patients underwent resection of the orbital ossifying fibroma with no macroscopic evidence of recurrence at 4 years follow-up. Full functional outcome was achieved with preservation of vision and facial nerve function as well as good facial symmetry and aesthetics. The successful surgical outcome of these cases was due to a combination of a multidisciplinary team approach, rigorous pre-operative planning, maximal tumour resection, and the use of a novel surgical technique involving a medial zygomatic-orbito-maxillary rotational osteotomy.
The Lancet Child & Adolescent Health, 2021
Research Square (Research Square), Dec 5, 2023
Ophthalmology, 2008
To compare the binocular near vision performance in patients implanted with the 1CU accommodating... more To compare the binocular near vision performance in patients implanted with the 1CU accommodating intraocular lens (IOL) with a multifocal and monofocal IOL. Design: Prospective, randomized, double-masked clinical trial. Participants: Ninety patients presenting for cataract surgery to the Department of Ophthalmology, Hillingdon Hospital were randomized to receive the 1CU accommodative IOL, a multifocal IOL, or a monofocal IOL (control group). Methods: Patients underwent bilateral sequential phacoemulsification with implantation of 1 of the 3 IOL types and were assessed at 3 and 18 months after second-eye surgery. Main Outcome Measures: Logarithm of the minimum angle of resolution distance and near visual acuities (VAs) (unaided and distance corrected), contrast sensitivity, and accommodative amplitude (near point and defocusing) were measured at 3 and 18 months. Reading speed was assessed at 18 months, and glare symptoms and spectacle independence were compared using a standardized questionnaire. Results: Mean unaided and distance-corrected binocular near VAs were similar in the 1CU and multifocal and were significantly higher than the control group's (PϽ0.02). There was no significant difference in reading speed between any of the groups, but critical print sizes were similar in the 1CU and multifocal groups and significantly better than the control group's (P ϭ 0.02). The accommodative range was highest in the multifocal group and lowest in the control group, and there was no significant difference between the 1CU and control groups for defocus or near point at 18 months. Of the 1CU group and control group, 71.4% and 63.2%, respectively, experienced no glare at 18 months, compared with only 25% of the multifocal group (P ϭ 0.01). Of the 1CU group and multifocal group, 19% and 27.3%, respectively, were completely spectacle independent at 18 months; none of the control group was (P ϭ 0.05). Conclusions: The 1CU accommodating IOL provides improved near vision compared with a monofocal IOL. There is a discrepancy between the near function and accommodative amplitude measured in the 1CU. The multifocal provides excellent near acuity, but photopic phenomena remain a problem inherent in the lens design.
Investigative Ophthalmology & Visual Science, Apr 17, 2010
Sclerotherapy treatment of orbital lymphatic malformations: a large single-centre experience
Eye, 2022
Spontaneous, non-traumatic paediatric vitreous haemorrhage may occur secondary to a persistent hy... more Spontaneous, non-traumatic paediatric vitreous haemorrhage may occur secondary to a persistent hyaloid artery, which is easily diagnosed if visible on fundoscopy. We present two cases of unexplained paediatric vitreous haemorrhage, referred to our tertiary clinic, in which optical coherence tomography angiography (OCT-A) was used to demonstrate flow through otherwise clinically occult, hyaloid and peripapillary arterial remnants. OCT-A may prevent the need for extensive investigations in some cases paediatric vitreous haemorrhage, previously classified as idiopathic.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2011
Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggress... more Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggressive biological behaviour in the paediatric population. Complete surgical excision, where possible, is the ideal. This case report discusses the multidisciplinary, surgical management of two complex cases of large juvenile ossifying fibroma (JOF), involving the orbit. Both patients underwent resection of the orbital ossifying fibroma with no macroscopic evidence of recurrence at 4 years follow-up. Full functional outcome was achieved with preservation of vision and facial nerve function as well as good facial symmetry and aesthetics. The successful surgical outcome of these cases was due to a combination of a multidisciplinary team approach, rigorous pre-operative planning, maximal tumour resection, and the use of a novel surgical technique involving a medial zygomatic-orbito-maxillary rotational osteotomy.
The British journal of ophthalmology, Jan 17, 2015
Percutaneous sclerotherapy is an alternative to surgery for the treatment of orbital lymphatic ma... more Percutaneous sclerotherapy is an alternative to surgery for the treatment of orbital lymphatic malformations (LMs). We present a large series of patients undergoing sclerotherapy for macrocystic LMs with detailed visual acuity (VA) outcome data. Data were collected prospectively in all patients with macrocystic orbital LMs undergoing sclerotherapy. Sclerotherapy was performed under general anaesthesia, instilling sodium tetradecyl sulfate under imaging control. Procedures were repeated at 2-week to 6-week intervals, depending on clinical response. Patients underwent ophthalmological assessment, ultrasound and/or MRI before and after treatment. change in maximal radiological diameter of the LM. Secondary outcome measure: change in VA after treatment. 29 patients underwent 71 procedures (1-8 procedures per patient) over 6.7 years. Mean age=7.31 years. 11 patients (37.9%) had undergone previous treatment, including excision biopsy, drainage and decompression. All patients presented wit...
Medical teacher, Jan 10, 2015
Journal of Plastic, Reconstructive & Aesthetic Surgery, 2011
Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggress... more Ossifying fibroma is a rare benign tumour of the craniofacial skeleton, which can have an aggressive biological behaviour in the paediatric population. Complete surgical excision, where possible, is the ideal. This case report discusses the multidisciplinary, surgical management of two complex cases of large juvenile ossifying fibroma (JOF), involving the orbit. Both patients underwent resection of the orbital ossifying fibroma with no macroscopic evidence of recurrence at 4 years follow-up. Full functional outcome was achieved with preservation of vision and facial nerve function as well as good facial symmetry and aesthetics. The successful surgical outcome of these cases was due to a combination of a multidisciplinary team approach, rigorous pre-operative planning, maximal tumour resection, and the use of a novel surgical technique involving a medial zygomatic-orbito-maxillary rotational osteotomy.