Sebnem sOYSAL - Academia.edu (original) (raw)
Papers by Sebnem sOYSAL
Journal of Child Neurology, 2003
Methylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate ... more Methylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate has not been clarified in patients with attention-deficit hyperactivity disorder (ADHD) and concomitant active seizure or electroencephalographic (EEG) abnormalities. Patients with ADHD and active seizures ( n = 57) and patients with ADHD and EEG abnormalities ( n = 62), 6 to 16 years of age, were included in the study. The safety and efficacy of treatment with antiepilepsy drugs combined with methylphenidate were determined by assessing seizure frequency, changes in ADHD symptoms, the Conners' Rating Scales, EEG differences, and side effects. The Conners' Rating Scales, performed by parents and teachers, and mean total ADHD symptom scores at the beginning of the study and at the end were significantly different ( P = .05 for the Conners' Rating Scales and P = .001 for ADHD symptom scores). Methylphenidate had a beneficial effect on EEG. Seizure frequency did not change from ...
Cumhuriyet Üniversitesi Edebiyat Fakültesi Sosyal Bilimler Dergisi, Dec 29, 2020
Çocukluk çağı korkuları, gelişimsel olarak normal kabul edilmektedir. Ancak patolojik noktaya gel... more Çocukluk çağı korkuları, gelişimsel olarak normal kabul edilmektedir. Ancak patolojik noktaya geldiğinde bu korkular çocuğun ve ailesinin hayat kalitesini olumsuz yönde etkilemektedir. Bu çalışmada çocukluk çağı korkularından biri olan gece korkusuna sanatla terapi ve yaratıcılık teknikleri kullanılarak müdahale edildiği bir olgu sunumu yapılmıştır. Tek başına uyumama yakınması bulunan olgu ile "Huzurlu Yastık Kılıfı" uygulaması çalışılmıştır. Bu uygulama gece uykuya dalma sorunu olan, uyuduktan bir süre sonrasında uyanarak anne-babanın yanına gitme ihtiyacı duyan çocuklara uygulanan bir yöntemdir. Yöntem çocukların kendi duygularının farkına varabilmeleri, yaşadıkları uyum güçlüklerinde bu duyguların ne derece etkili olduğunu fark etmelerinin sağlanmasını amaçlamaktadır. Çalışma içerisinde uygulama öncesi yapılan ısınma etkinlikleri, ana uygulama ve sonrasında ortaya çıkan temalar üzerinde yürütülen terapi süreci açıklanmıştır. Uygulama sonucunda olgunun gece korkusunun azalmış ve uyku hijyeninde iyileşme sağlanmıştır. Bu çalışma, çocukluk çağı korkularının normal kabul edilmelerinin sonucunda terapi ortamlarında ihmal edilmesinin önüne geçilmesi ile sanatla terapi ve yaratıcılık tekniklerinin bu alanda kullanılmasına dikkat çekmek için kaleme alınmıştır.
Objectives: We aimed to investigate depression, burnout, attitude, and burden of caregivers of ch... more Objectives: We aimed to investigate depression, burnout, attitude, and burden of caregivers of children with cystic fibrosis (CF), and especially caregivers of children with primary ciliary dyskinesia (PCD) due to limited number of studies on this topic, and to compare them according to their children’s clinical status. Methods: Clinical features and demographic data of children and their families were asked to caregivers in four pediatric pulmonology centers. Beck Depression Inventory (BDI), Maslach Burnout Inventory (MBI), Zarit Caregiver Burden Scale (ZCBS), and Parental Attitude Research Instrument (PARI) were administered to caregivers in both groups. Results were compared between the two groups. Results: In total, 131 children with CF and 39 with PCD and their caregivers were involved in study. All primary caregivers were mothers in both groups. Depression, burnout, and burden scores of mothers of children with CF were significantly higher than mothers of children with PCD (p=...
İDEALKENT, 2019
Tasarım egzersizleri, yaratıcı drama ve sanatla terapi teknikleri kullanarak, iklim değişikliği v... more Tasarım egzersizleri, yaratıcı drama ve sanatla terapi teknikleri kullanarak, iklim değişikliği ve buna bağlı olarak yaşanan ve yaşanacak olan değişiklikler üzerine çocuklara ve gençlere yönelik bilgilendirme ve farkındalık oluşturma; uyum ve işbirliği yetilerini güçlendirme; ve bu süreçlerin oluşturabileceği olumsuz duygudurumları ile baş edebilme becerisi kazandırma amaçları doğrultusunda ilki 2017 yılı ocak ayı, ikincisi ise 2018 yılı ocak ayında olmak üzere, farklı yaş gruplarına yönelik iki atölye çalışması yapılmıştır. Atölyeler, TOBB Ekonomi ve Teknoloji Üniversitesi Mimarlık Bölümü 1. Sınıf Temel Tasarım Stüdyosu öğrencileri ile Abdurrahim Karakoç İlkokulu öğrencilerinin katılımı ile TOBB Ekonomi ve Teknoloji Üniversitesi Teknoloji Merkezi Binası'nda yer alan Mimarlık Bölümü stüdyolarında gerçekleştirilmiştir. Bir yıl arayla yapılan bu iki çalışmanın farklı yaş, cinsiyet ve eğitim durumuna göre bireyler üzerinde farklılaşma yarattığı görüldü. Değerlendirmeler sonucunda, atölyelerin tüm katılımcı ve yürütücüler için önemli bir deneyim, farkındalık, bilgi ve beceri kazanımı sağladığından hareketle, etkinliğin diğer ilköğretim okullarına yaygınlaştırılması için çalışma yapılması kararı alınmıştır.
Pediatrics International, 2003
Background : Multiple gestations are known to bring some risks in the prenatal and natal period, ... more Background : Multiple gestations are known to bring some risks in the prenatal and natal period, but whether it is a risk for development in childhood is a matter of debate. The aim of the present study was to evaluate physical and mental development of Turkish twins and then to assess whether being a twin poses risks for their development. Methods : Fifty-two twin pairs (104 children) aged between 1 and 5 years were enroled in the study. The control group consisted of 91 singletons, who were matched according to age, sex, gestational week and maternal educational level. The Denver Developmental Screening Test (DDST) was administered to assess cognitive development. Student t-test and χ 2 test were used to compare the two groups. Results : The mean age of the mothers of twins did not differ from that of singleton mothers (P > 0.05). Twins were more frequently born in cases of assisted fertilization and were more often born via cesarean section. The birthweights of twins were lower and they were more frequently hospitalized after birth. The breast feeding period was shorter in twins and they had more chronic diseases than singletons (P < 0.05). Mothers of twins needed more help while caring for their infants. Physical development of twins and singletons did not differ statistically (P > 0.05). Twins had more suspect and delayed results in the DDST, especially in the language section of the test. Conclusion : Physical and mental development of twins does not differ significantly from singletons except that twins might have a tendency towards slow language acquisition.
Journal of Tropical Pediatrics, 2005
Introduction Grade retention during the early years of education may have detrimental results suc... more Introduction Grade retention during the early years of education may have detrimental results such as increased dropout rate and decreased self-esteem. 1 Retention also creates a burden on the community. It has been estimated that developing countries have to spend four times more to produce a graduate after retention. 2 Grade retention rates during primary school were reported to be 7.6 per cent in the USA. 3 In Turkey the grade retention rate among primary school students between 1994 and 1995 was 2.5 per cent (341 379 students). 4 As retention is costly and long-term consequences are detrimental, it has become a policy in many countries to make the student go through grades as much as possible during the primary school years. As a result there are many more students with low school performance than those repeating a grade. Decreased primary school performance is a risk factor for low high-school and university graduation, as well as an increased risk for poverty in later life. 5 In this study we aimed to define the relationship and interaction between several physical, environmental and sociodemographic factors, and primary school performance in a developing country using physical examination, laboratory tests, Child Behavior Checklist (CBCL), Wechsler Intellegence Scale for Children-Revised adopted for Turkish Children (WISC-R), as well as parent interviews.
Çocuk Sağlığı ve Hastalıkları Dergisi, 2001
Journal of Pediatric Endocrinology and Metabolism, 2002
Objective: To investigate the frequency, etiology and consequences of neonatal hypoglycemia. Stud... more Objective: To investigate the frequency, etiology and consequences of neonatal hypoglycemia. Study design: Ninety-four infants admitted to Gazi University Hospital neonatal intensive care unit for hypoglycemia (blood glucose <2.2 mmol/1 [40 mg/dl]) over the past 5 years were identified and investigated with regard to cause, duration of treatment and neurological outcome. Results: The frequency of neonatal hypoglycemia in our unit was 94/1,023 (9.18%). Twelve infants with hypoglycemia were small for gestational age (SGA), 55 were appropriate for gestational age (AGA), and 27 were large for gestational age (LGA). The cause of the hypoglycemia was not identified in 53 infants. SGA infants required the longest duration of i.v. glucose infusion. Forty-eight patients received psychometric evaluation, one patient showed a language deficit and two patients showed motor deficits. Conclusion: Neonatal hypoglycemia is a dangerous condition for its acute and chronic complications, and may be observed in infants with no clear risk factors. However, if acted upon early, these complications are preventable with mostly very simple measures.
Background: The rate of congenital heart disease is 0.8 % in all live births. The majority of thi... more Background: The rate of congenital heart disease is 0.8 % in all live births. The majority of this, however, is acyanotic congenital heart disease. The survival rate of children with cardiac disease has increased with the developments provided in recent years and their lifetime is extended. Objectives: This study aims to evaluate neurodevelopment of children with uncomplicated acyanotic congenital heart disease in preschool period and determine the factors affecting their neurodevelopmental process. Patients and Methods: 132 children with acyanotic congenital heart disease aged 6- 72 months were involved in the study. Mental development and intelligence levels of patients under 2 years old were assessed by using Bayley Development Scale-III, and Stanford Binet Intelligence test was employed for patients over 2 years old. Denver Developmental Screening Test II was applied to all patients for their personal-social, fine motor, gross motor and language development. Results: The average...
Effects of attention deficit and hyperacitivity disorder subtypes on family functions Objective: ... more Effects of attention deficit and hyperacitivity disorder subtypes on family functions Objective: Attention deficiency and hyperactivity disorder (ADHD) is a mental disorder that seriously affects both the individual and his/her family. The aim of this study is to evaluate family functions of individuals with different subtypes of ADHD who have no significant cognitive and social impairments. Methods: 27, 18, and 32 subjects with ADHD-inattentive (ADHD-I), ADHD-hyperactivity-impulsivity (ADHD-HI) and ADHD-combined (ADHD-C) subtypes, respectively, and 35 control subjects aged 6 to 10 years and their mothers were included in the study. Wechsler Intelligence Scale For Children, Conners Parent And Teacher Rating Scales and Family Assessment Scale (FAS) were used. Results: FAS subtests indicated that problem solving score of ADHD-HI subgroup, communication score of ADHD-I subgroup, roles score of ADHD-C subgroup, “showing necessary interest ” scores of ADHD-I and ADHD-HI subgroups, and ge...
Journal of Asthma
Introduction: Montelukast-induced neuropsychiatric adverse drug reactions (ADRs) have been report... more Introduction: Montelukast-induced neuropsychiatric adverse drug reactions (ADRs) have been reported in retrospective studies. This study aimed to reveal the neuropsychiatric ADRs triggered in patients taking montelukast due to asthma in real time, and to evaluate the effect of these ADRs on quality of life (QoL). Methods: Patients, ages 3-18 years, taking montelukast for the first time and their parents were included. Ages 3-7 years were defined as the preschool and ages 8 - 18 years as the school-age group. At the beginning of the study and at the end of the second week of treatment, the neuropsychiatric complaint assessment questionnaire and the KINDL QoL scale were administered to patients and their parents. The effect of ADRs on the decrease in QoL was evaluated by multivariable logistic regression. Results: Neuropsychiatric ADRs were reported in 78 (62.4%) of 125 patients, who recovered when the drug was discontinued. Temperamental behavior, nightmares and sleep disorders occurred significantly more often in both groups compared with pre-treatment (p < 0.001 for each). In both groups, except in the child-reported family relationships subscale in the school-age group, significant decreases were found in both child and parent proxy-reported QoL total/sub-scores compared with pre-treatment (p˂0.001 for each). It was found in the evaluation that the overall QoL of those experiencing ADRs in both age groups was more affected. (Child-reported QoL ORpre-school age=2.66, p = 0.048; ORschool-age=5.95, p = 0.027; parent-proxy QoL ORpre-school age =3.52, p = 0.010, ORschool-age=6.43, p = 0.027) Conclusions: Montelukast-induced neuropsychiatric ADRs are more frequent than reported in the literature and negatively impact children's QoL.
Journal of Paediatrics and Child Health
We aimed to investigate sleep disturbances in children with cystic fibrosis (CF) and primary cili... more We aimed to investigate sleep disturbances in children with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) and typically developing (TD) children during the COVID‐19 pandemic.
Pediatric Pulmonology
We aimed to evaluate anxiety among children with cystic fibrosis (CF) and their mothers related t... more We aimed to evaluate anxiety among children with cystic fibrosis (CF) and their mothers related to the COVID‐19 pandemic.
Journal of Paediatrics and Child Health
In this study, we aimed to determine the psychosocial status of primary care givers of children w... more In this study, we aimed to determine the psychosocial status of primary care givers of children with cystic fibrosis (CF) and its relationship with the clinical scores of children with CF.
METU JOURNAL OF THE FACULTY OF ARCHITECTURE
degrees in clinical psychology from Hacettepe University. Earned her PhD degree in experimental p... more degrees in clinical psychology from Hacettepe University. Earned her PhD degree in experimental psychology also from Hacettepe University. Currently takes part in international neuropsychological researches, Phase-1 clinical trials. Research interests include child development, child psychology, family guide, art therapy techniques in education.
METU Journal of the Faculty of Architecture, 2019
Spatial cognition and skills are of critical importance for architecture. During their education,... more Spatial cognition and skills are of critical importance for architecture. During their education, architecture students are expected to use and develop visuospatial skills to generate/construct, retain, rotate, and manipulate space mentally and physically through physical and digital representations. This study was designed and conducted to fill the gap in researches on the first-year architecture students’ spatial skill evaluated by means of neuropsychological tests. The goal of the study was to investigate the potential connections between the visuospatial skills, university entrance exam scores and cognitive development of the first architecture students. 128 students participated to the research voluntarily. For visuospatial skills Raven Standard Progressive Matrices (RSPM) test was administrated. Logical Thinking Test was used for the assessment of cognitive development level. Participants with art training prior to university performed better in RSPM total, and RSPM subtest E....
International Journal of Art & Design Education
Child's Nervous System
More information is needed on &amp;amp;amp;quot;low-risk&amp;amp;amp;quot; preter... more More information is needed on &amp;amp;amp;quot;low-risk&amp;amp;amp;quot; preterm infants&amp;amp;amp;#39; neurological outcome so that they can be included in follow-up programs. A prospective study was performed to examine the regional brain volume changes compared to term children and to assess the relationship between the regional brain volumes to cognitive outcome of the low-risk preterm children at 9 years of age. Subjects comprised 22 preterm children who were determined to be at low risk for neurodevelopmental deficits with a gestational age between 28 and 33 weeks without a major neonatal morbidity in the neonatal period and 24 age-matched term control children term and matched for age, sex, and parental educational and occupational status. Regional volumetric analysis was performed for cerebellum, hippocampus, and corpus callosum area. Cognitive outcomes of both preterm and control subjects were assessed by Weschler Intelligence Scale for Children Revised (Turkish version), and attention and executive functions were assessed by Wisconsin Card Sorting Test and Stroop Test TBAG version. Low-risk preterm children showed regional brain volume reduction in cerebellum, hippocampus, and corpus callosum area and achieved statistical significance when compared with term control. When the groups were compared for all WISC-R subscale scores, preterm children at low risk had significantly lower scores on information, vocabulary, similarities, arithmetics, picture completion, block design, object assembly, and coding compared to children born at term. Preterm and term groups were compared on the Stroop Test for mistakes and corrections made on each card, the time spent for completing each card, and total mistakes and corrections. In the preterm group, we found a positive correlation between regional volumes with IQ, attention, and executive function scores. Additionally, a significant correlation was found between cerebellar volume and attention and executive function scores in the preterm group. Low-risk preterm children achieve lower scores in neurophysiological tests than children born at term. Preterm birth itself has a significant impact on regional brain volumes and cognitive outcome of children at 9 years of age. It is a risk factor for regional brain volume reductions in preterm children with low risk for neurodevelopmental deficits. The significant interaction between cerebellar volume reduction and executive function and attention may suggest that even in preterm children at low risk can have different trajectories in the growth and development of overall brain structure.
Journal of Child Neurology, 2003
Methylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate ... more Methylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate has not been clarified in patients with attention-deficit hyperactivity disorder (ADHD) and concomitant active seizure or electroencephalographic (EEG) abnormalities. Patients with ADHD and active seizures ( n = 57) and patients with ADHD and EEG abnormalities ( n = 62), 6 to 16 years of age, were included in the study. The safety and efficacy of treatment with antiepilepsy drugs combined with methylphenidate were determined by assessing seizure frequency, changes in ADHD symptoms, the Conners' Rating Scales, EEG differences, and side effects. The Conners' Rating Scales, performed by parents and teachers, and mean total ADHD symptom scores at the beginning of the study and at the end were significantly different ( P = .05 for the Conners' Rating Scales and P = .001 for ADHD symptom scores). Methylphenidate had a beneficial effect on EEG. Seizure frequency did not change from ...
Cumhuriyet Üniversitesi Edebiyat Fakültesi Sosyal Bilimler Dergisi, Dec 29, 2020
Çocukluk çağı korkuları, gelişimsel olarak normal kabul edilmektedir. Ancak patolojik noktaya gel... more Çocukluk çağı korkuları, gelişimsel olarak normal kabul edilmektedir. Ancak patolojik noktaya geldiğinde bu korkular çocuğun ve ailesinin hayat kalitesini olumsuz yönde etkilemektedir. Bu çalışmada çocukluk çağı korkularından biri olan gece korkusuna sanatla terapi ve yaratıcılık teknikleri kullanılarak müdahale edildiği bir olgu sunumu yapılmıştır. Tek başına uyumama yakınması bulunan olgu ile "Huzurlu Yastık Kılıfı" uygulaması çalışılmıştır. Bu uygulama gece uykuya dalma sorunu olan, uyuduktan bir süre sonrasında uyanarak anne-babanın yanına gitme ihtiyacı duyan çocuklara uygulanan bir yöntemdir. Yöntem çocukların kendi duygularının farkına varabilmeleri, yaşadıkları uyum güçlüklerinde bu duyguların ne derece etkili olduğunu fark etmelerinin sağlanmasını amaçlamaktadır. Çalışma içerisinde uygulama öncesi yapılan ısınma etkinlikleri, ana uygulama ve sonrasında ortaya çıkan temalar üzerinde yürütülen terapi süreci açıklanmıştır. Uygulama sonucunda olgunun gece korkusunun azalmış ve uyku hijyeninde iyileşme sağlanmıştır. Bu çalışma, çocukluk çağı korkularının normal kabul edilmelerinin sonucunda terapi ortamlarında ihmal edilmesinin önüne geçilmesi ile sanatla terapi ve yaratıcılık tekniklerinin bu alanda kullanılmasına dikkat çekmek için kaleme alınmıştır.
Objectives: We aimed to investigate depression, burnout, attitude, and burden of caregivers of ch... more Objectives: We aimed to investigate depression, burnout, attitude, and burden of caregivers of children with cystic fibrosis (CF), and especially caregivers of children with primary ciliary dyskinesia (PCD) due to limited number of studies on this topic, and to compare them according to their children’s clinical status. Methods: Clinical features and demographic data of children and their families were asked to caregivers in four pediatric pulmonology centers. Beck Depression Inventory (BDI), Maslach Burnout Inventory (MBI), Zarit Caregiver Burden Scale (ZCBS), and Parental Attitude Research Instrument (PARI) were administered to caregivers in both groups. Results were compared between the two groups. Results: In total, 131 children with CF and 39 with PCD and their caregivers were involved in study. All primary caregivers were mothers in both groups. Depression, burnout, and burden scores of mothers of children with CF were significantly higher than mothers of children with PCD (p=...
İDEALKENT, 2019
Tasarım egzersizleri, yaratıcı drama ve sanatla terapi teknikleri kullanarak, iklim değişikliği v... more Tasarım egzersizleri, yaratıcı drama ve sanatla terapi teknikleri kullanarak, iklim değişikliği ve buna bağlı olarak yaşanan ve yaşanacak olan değişiklikler üzerine çocuklara ve gençlere yönelik bilgilendirme ve farkındalık oluşturma; uyum ve işbirliği yetilerini güçlendirme; ve bu süreçlerin oluşturabileceği olumsuz duygudurumları ile baş edebilme becerisi kazandırma amaçları doğrultusunda ilki 2017 yılı ocak ayı, ikincisi ise 2018 yılı ocak ayında olmak üzere, farklı yaş gruplarına yönelik iki atölye çalışması yapılmıştır. Atölyeler, TOBB Ekonomi ve Teknoloji Üniversitesi Mimarlık Bölümü 1. Sınıf Temel Tasarım Stüdyosu öğrencileri ile Abdurrahim Karakoç İlkokulu öğrencilerinin katılımı ile TOBB Ekonomi ve Teknoloji Üniversitesi Teknoloji Merkezi Binası'nda yer alan Mimarlık Bölümü stüdyolarında gerçekleştirilmiştir. Bir yıl arayla yapılan bu iki çalışmanın farklı yaş, cinsiyet ve eğitim durumuna göre bireyler üzerinde farklılaşma yarattığı görüldü. Değerlendirmeler sonucunda, atölyelerin tüm katılımcı ve yürütücüler için önemli bir deneyim, farkındalık, bilgi ve beceri kazanımı sağladığından hareketle, etkinliğin diğer ilköğretim okullarına yaygınlaştırılması için çalışma yapılması kararı alınmıştır.
Pediatrics International, 2003
Background : Multiple gestations are known to bring some risks in the prenatal and natal period, ... more Background : Multiple gestations are known to bring some risks in the prenatal and natal period, but whether it is a risk for development in childhood is a matter of debate. The aim of the present study was to evaluate physical and mental development of Turkish twins and then to assess whether being a twin poses risks for their development. Methods : Fifty-two twin pairs (104 children) aged between 1 and 5 years were enroled in the study. The control group consisted of 91 singletons, who were matched according to age, sex, gestational week and maternal educational level. The Denver Developmental Screening Test (DDST) was administered to assess cognitive development. Student t-test and χ 2 test were used to compare the two groups. Results : The mean age of the mothers of twins did not differ from that of singleton mothers (P > 0.05). Twins were more frequently born in cases of assisted fertilization and were more often born via cesarean section. The birthweights of twins were lower and they were more frequently hospitalized after birth. The breast feeding period was shorter in twins and they had more chronic diseases than singletons (P < 0.05). Mothers of twins needed more help while caring for their infants. Physical development of twins and singletons did not differ statistically (P > 0.05). Twins had more suspect and delayed results in the DDST, especially in the language section of the test. Conclusion : Physical and mental development of twins does not differ significantly from singletons except that twins might have a tendency towards slow language acquisition.
Journal of Tropical Pediatrics, 2005
Introduction Grade retention during the early years of education may have detrimental results suc... more Introduction Grade retention during the early years of education may have detrimental results such as increased dropout rate and decreased self-esteem. 1 Retention also creates a burden on the community. It has been estimated that developing countries have to spend four times more to produce a graduate after retention. 2 Grade retention rates during primary school were reported to be 7.6 per cent in the USA. 3 In Turkey the grade retention rate among primary school students between 1994 and 1995 was 2.5 per cent (341 379 students). 4 As retention is costly and long-term consequences are detrimental, it has become a policy in many countries to make the student go through grades as much as possible during the primary school years. As a result there are many more students with low school performance than those repeating a grade. Decreased primary school performance is a risk factor for low high-school and university graduation, as well as an increased risk for poverty in later life. 5 In this study we aimed to define the relationship and interaction between several physical, environmental and sociodemographic factors, and primary school performance in a developing country using physical examination, laboratory tests, Child Behavior Checklist (CBCL), Wechsler Intellegence Scale for Children-Revised adopted for Turkish Children (WISC-R), as well as parent interviews.
Çocuk Sağlığı ve Hastalıkları Dergisi, 2001
Journal of Pediatric Endocrinology and Metabolism, 2002
Objective: To investigate the frequency, etiology and consequences of neonatal hypoglycemia. Stud... more Objective: To investigate the frequency, etiology and consequences of neonatal hypoglycemia. Study design: Ninety-four infants admitted to Gazi University Hospital neonatal intensive care unit for hypoglycemia (blood glucose <2.2 mmol/1 [40 mg/dl]) over the past 5 years were identified and investigated with regard to cause, duration of treatment and neurological outcome. Results: The frequency of neonatal hypoglycemia in our unit was 94/1,023 (9.18%). Twelve infants with hypoglycemia were small for gestational age (SGA), 55 were appropriate for gestational age (AGA), and 27 were large for gestational age (LGA). The cause of the hypoglycemia was not identified in 53 infants. SGA infants required the longest duration of i.v. glucose infusion. Forty-eight patients received psychometric evaluation, one patient showed a language deficit and two patients showed motor deficits. Conclusion: Neonatal hypoglycemia is a dangerous condition for its acute and chronic complications, and may be observed in infants with no clear risk factors. However, if acted upon early, these complications are preventable with mostly very simple measures.
Background: The rate of congenital heart disease is 0.8 % in all live births. The majority of thi... more Background: The rate of congenital heart disease is 0.8 % in all live births. The majority of this, however, is acyanotic congenital heart disease. The survival rate of children with cardiac disease has increased with the developments provided in recent years and their lifetime is extended. Objectives: This study aims to evaluate neurodevelopment of children with uncomplicated acyanotic congenital heart disease in preschool period and determine the factors affecting their neurodevelopmental process. Patients and Methods: 132 children with acyanotic congenital heart disease aged 6- 72 months were involved in the study. Mental development and intelligence levels of patients under 2 years old were assessed by using Bayley Development Scale-III, and Stanford Binet Intelligence test was employed for patients over 2 years old. Denver Developmental Screening Test II was applied to all patients for their personal-social, fine motor, gross motor and language development. Results: The average...
Effects of attention deficit and hyperacitivity disorder subtypes on family functions Objective: ... more Effects of attention deficit and hyperacitivity disorder subtypes on family functions Objective: Attention deficiency and hyperactivity disorder (ADHD) is a mental disorder that seriously affects both the individual and his/her family. The aim of this study is to evaluate family functions of individuals with different subtypes of ADHD who have no significant cognitive and social impairments. Methods: 27, 18, and 32 subjects with ADHD-inattentive (ADHD-I), ADHD-hyperactivity-impulsivity (ADHD-HI) and ADHD-combined (ADHD-C) subtypes, respectively, and 35 control subjects aged 6 to 10 years and their mothers were included in the study. Wechsler Intelligence Scale For Children, Conners Parent And Teacher Rating Scales and Family Assessment Scale (FAS) were used. Results: FAS subtests indicated that problem solving score of ADHD-HI subgroup, communication score of ADHD-I subgroup, roles score of ADHD-C subgroup, “showing necessary interest ” scores of ADHD-I and ADHD-HI subgroups, and ge...
Journal of Asthma
Introduction: Montelukast-induced neuropsychiatric adverse drug reactions (ADRs) have been report... more Introduction: Montelukast-induced neuropsychiatric adverse drug reactions (ADRs) have been reported in retrospective studies. This study aimed to reveal the neuropsychiatric ADRs triggered in patients taking montelukast due to asthma in real time, and to evaluate the effect of these ADRs on quality of life (QoL). Methods: Patients, ages 3-18 years, taking montelukast for the first time and their parents were included. Ages 3-7 years were defined as the preschool and ages 8 - 18 years as the school-age group. At the beginning of the study and at the end of the second week of treatment, the neuropsychiatric complaint assessment questionnaire and the KINDL QoL scale were administered to patients and their parents. The effect of ADRs on the decrease in QoL was evaluated by multivariable logistic regression. Results: Neuropsychiatric ADRs were reported in 78 (62.4%) of 125 patients, who recovered when the drug was discontinued. Temperamental behavior, nightmares and sleep disorders occurred significantly more often in both groups compared with pre-treatment (p < 0.001 for each). In both groups, except in the child-reported family relationships subscale in the school-age group, significant decreases were found in both child and parent proxy-reported QoL total/sub-scores compared with pre-treatment (p˂0.001 for each). It was found in the evaluation that the overall QoL of those experiencing ADRs in both age groups was more affected. (Child-reported QoL ORpre-school age=2.66, p = 0.048; ORschool-age=5.95, p = 0.027; parent-proxy QoL ORpre-school age =3.52, p = 0.010, ORschool-age=6.43, p = 0.027) Conclusions: Montelukast-induced neuropsychiatric ADRs are more frequent than reported in the literature and negatively impact children's QoL.
Journal of Paediatrics and Child Health
We aimed to investigate sleep disturbances in children with cystic fibrosis (CF) and primary cili... more We aimed to investigate sleep disturbances in children with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) and typically developing (TD) children during the COVID‐19 pandemic.
Pediatric Pulmonology
We aimed to evaluate anxiety among children with cystic fibrosis (CF) and their mothers related t... more We aimed to evaluate anxiety among children with cystic fibrosis (CF) and their mothers related to the COVID‐19 pandemic.
Journal of Paediatrics and Child Health
In this study, we aimed to determine the psychosocial status of primary care givers of children w... more In this study, we aimed to determine the psychosocial status of primary care givers of children with cystic fibrosis (CF) and its relationship with the clinical scores of children with CF.
METU JOURNAL OF THE FACULTY OF ARCHITECTURE
degrees in clinical psychology from Hacettepe University. Earned her PhD degree in experimental p... more degrees in clinical psychology from Hacettepe University. Earned her PhD degree in experimental psychology also from Hacettepe University. Currently takes part in international neuropsychological researches, Phase-1 clinical trials. Research interests include child development, child psychology, family guide, art therapy techniques in education.
METU Journal of the Faculty of Architecture, 2019
Spatial cognition and skills are of critical importance for architecture. During their education,... more Spatial cognition and skills are of critical importance for architecture. During their education, architecture students are expected to use and develop visuospatial skills to generate/construct, retain, rotate, and manipulate space mentally and physically through physical and digital representations. This study was designed and conducted to fill the gap in researches on the first-year architecture students’ spatial skill evaluated by means of neuropsychological tests. The goal of the study was to investigate the potential connections between the visuospatial skills, university entrance exam scores and cognitive development of the first architecture students. 128 students participated to the research voluntarily. For visuospatial skills Raven Standard Progressive Matrices (RSPM) test was administrated. Logical Thinking Test was used for the assessment of cognitive development level. Participants with art training prior to university performed better in RSPM total, and RSPM subtest E....
International Journal of Art & Design Education
Child's Nervous System
More information is needed on &amp;amp;amp;quot;low-risk&amp;amp;amp;quot; preter... more More information is needed on &amp;amp;amp;quot;low-risk&amp;amp;amp;quot; preterm infants&amp;amp;amp;#39; neurological outcome so that they can be included in follow-up programs. A prospective study was performed to examine the regional brain volume changes compared to term children and to assess the relationship between the regional brain volumes to cognitive outcome of the low-risk preterm children at 9 years of age. Subjects comprised 22 preterm children who were determined to be at low risk for neurodevelopmental deficits with a gestational age between 28 and 33 weeks without a major neonatal morbidity in the neonatal period and 24 age-matched term control children term and matched for age, sex, and parental educational and occupational status. Regional volumetric analysis was performed for cerebellum, hippocampus, and corpus callosum area. Cognitive outcomes of both preterm and control subjects were assessed by Weschler Intelligence Scale for Children Revised (Turkish version), and attention and executive functions were assessed by Wisconsin Card Sorting Test and Stroop Test TBAG version. Low-risk preterm children showed regional brain volume reduction in cerebellum, hippocampus, and corpus callosum area and achieved statistical significance when compared with term control. When the groups were compared for all WISC-R subscale scores, preterm children at low risk had significantly lower scores on information, vocabulary, similarities, arithmetics, picture completion, block design, object assembly, and coding compared to children born at term. Preterm and term groups were compared on the Stroop Test for mistakes and corrections made on each card, the time spent for completing each card, and total mistakes and corrections. In the preterm group, we found a positive correlation between regional volumes with IQ, attention, and executive function scores. Additionally, a significant correlation was found between cerebellar volume and attention and executive function scores in the preterm group. Low-risk preterm children achieve lower scores in neurophysiological tests than children born at term. Preterm birth itself has a significant impact on regional brain volumes and cognitive outcome of children at 9 years of age. It is a risk factor for regional brain volume reductions in preterm children with low risk for neurodevelopmental deficits. The significant interaction between cerebellar volume reduction and executive function and attention may suggest that even in preterm children at low risk can have different trajectories in the growth and development of overall brain structure.