Selma Raymundo - Academia.edu (original) (raw)

Papers by Selma Raymundo

Supplemental_Material_Study_Sites for Efficacy and Safety of a Biosimilar Versus Branded Enoxapar... more Supplemental_Material_Study_Sites for Efficacy and Safety of a Biosimilar Versus Branded Enoxaparin in the Prevention of Venous Thromboembolism Following Major Abdominal Surgery: A Randomized, Prospective, Single-Blinded, Multicenter Clinical Trial by Eduardo Ramacciotti, Ubirajara Ferreira, Agenor José Vasconcelos Costa, Selma Regina O. Raymundo, João Antônio Correa, Salvador Gullo Neto, Alessandro Bersch Osvaldt, Leandro Agati, Valéria Cristina Resende Aguiar, Ronaldo Davila, Tania Benevenuto Caltabiano, Flávia Magalhães Magella, Giuliano Giova Volpiani, Valter Castelli, Roberto Augusto Caffaro, Lucas Zeponi DalAcqua, Wagner Eduardo Matheus, Debora Yuri Sato, Gleison Juliano da Silva Russeff, Daniela Garcia de Souza, Lucas Eduardo Pazetto, Tiago Aparecido Maschio de Lima, Eloá Maria da Silva Colnago, Eliane Yumii Fugii, Juliana Sekeres Mussalem, Vanessa Therumi Assao, Odaly Toffoletto, Debora Garcia Rodrigues, Jorge Barros Afiune, and Gilson Roberto Araujo in Clinical and Applied ...

Journal of Thrombosis and Thrombolysis, 2020

Annals of Vascular Surgery

Journal of Thrombosis and Haemostasis, 2019

Essentials  GARFIELD-VTE records routine venous thromboembolism (VTE) treatment practices worldw... more Essentials  GARFIELD-VTE records routine venous thromboembolism (VTE) treatment practices worldwide.  Direct oral anticoagulants (DOACs) are frequently used instead of conventional AC treatments.  The use of DOACs sometimes differs from the recommended indications and the labelling.  Conventional anticoagulants are not always provided according to guideline recommendations.

Jornal Vascular Brasileiro, Jun 26, 2019

Cateterização profilática de artérias uterinas com oclusão temporária do fluxo sanguíneo em pacie... more Cateterização profilática de artérias uterinas com oclusão temporária do fluxo sanguíneo em pacientes de alto risco para hemorragia puerperal: é uma técnica segura?

Jornal Vascular Brasileiro, Jan 30, 2019

What has changed in venous thromboembolism prophylaxis for hospitalized patients over recent deca... more What has changed in venous thromboembolism prophylaxis for hospitalized patients over recent decades: review article O que mudou nas últimas décadas na profilaxia do tromboembolismo venoso em pacientes internados: artigo de revisão

Jornal Vascular Brasileiro, 2021

Visceral artery aneurysms (VAAs) and visceral artery pseudoaneurysms (VAPAs) are rare conditions ... more Visceral artery aneurysms (VAAs) and visceral artery pseudoaneurysms (VAPAs) are rare conditions and are potentially lethal when they rupture. They are usually found as incidental findings on computed tomography (CT) scans of asymptomatic patients. Although conventional open surgery is currently considered the gold standard treatment, the endovascular approach has gained prominence as a minimally invasive procedure with lower surgical risk. In this approach, use of coil embolization in saccular VAAs and VAPAs and implantation of flow-modulating stents constitute alternative treatments for fusiform aneurysms. We present the case of a 51-year-old female patient complaining of acute abdominal pain, tachycardia, and hypotension, with evidence of abdominal bleeding on CT angiography, who was diagnosed with a ruptured ileocolic artery (ICA) pseudoaneurysm. She underwent early endovascular treatment for ICA embolization, which was successful and achieved clinical improvement.

Free-floating thrombus in the deep venous system has a high potential to cause pulmonary emboliza... more Free-floating thrombus in the deep venous system has a high potential to cause pulmonary embolization. It can also be found in patients with superficial venous thrombosis (SVT) that extends to a deep vein. There are still no defined criteria for treatments described in the literature, which range from anticoagulation and fibrinolytic treatments with vena cava filter implants, through open or endovascular thrombectomies, to more invasive procedures such as surgical interruption with ligation of the venous system. We present the case of a patient with extensive deep venous thrombosis affecting the iliofemoral-popliteal territory with a floating thrombus extending from the left common iliac vein to the inferior vena cava. Treatment was performed with fibrinolytic therapy delivered with a multiperforated catheter, supplemented with anticoagulation with heparin and daily control angiography. At the end of the treatment, a significant stenosis was identified in the left common iliac vein,...

Background Placenta accreta is an important factor in maternal morbidity and mortality and is res... more Background Placenta accreta is an important factor in maternal morbidity and mortality and is responsible for approximately 64% of emergency hysterectomy cases and about 2/3 of cases of puerperal bleeding. Objectives To describe a series of cases of prophylactic uterine catheterization performed to prevent significant postpartum bleeding or during caesarean delivery in pregnant women with a previous diagnosis of accretion. Methods A retrospective analysis was conducted of medical records of cases of uterine artery catheterization performed during elective or emergency caesarean sections of patients at high risk of postpartum bleeding. Results The catheterization of uterine arteries procedure was performed in fourteen patients. Mean duration of surgery and hospital stay were 214.64 minutes (± 42.16) and 7 days, respectively. All patients underwent obstetric hysterectomy. No patient required embolization. There was no bleeding or need to revisit any patient and there were no complicat...

Artificial Organs, 2000

Porous three-dimensional collagen/chitosan scaffolds combined with poly (ethylene glycol) (PEG) a... more Porous three-dimensional collagen/chitosan scaffolds combined with poly (ethylene glycol) (PEG) and hydroxyapatite were obtained through a freeze-drying method. Physical cross-linking was examined by dehydrothermal treatment. The prepared materials were characterized by different analyses, eg, scanning electron microscopy (SEM), measurements of porosity and swelling, mechanical properties, and resistance to enzymatic degradation. The porosity of scaffolds and their swelling ratio decreased with the addition of hydroxyapatite. Moreover, after exposure to collagenase, the collagen/chitosan matrices containing PEG showed much faster degradation rate than matrices with the addition of hydroxyapatite. The results indicated that the addition of hydroxyapatite led to improvement of stiffness. The highest degree of porosity and swelling were demonstrated by collagen/chitosan/PEG matrices without hydroxyapatite.

Journal of Critical Care, 2017

and to estimate the effect of the Nursing Activities Score on the response time of the users to t... more and to estimate the effect of the Nursing Activities Score on the response time of the users to the alarms of the multiparameter monitors. Methods: Cross-sectional, observational study with open cohort performed in a 10-bed intensive care unit, where the timing of alarms triggered by the multiparameter monitors that presented clinical alteration was timed. Patients who were receiving cardiopulmonary resuscitation maneuvers were excluded. The ethical premises were respected. The data were analyzed in statistical software R version x 64 3.1.1. Descriptive statistics, logistic regression analysis, and survival analysis were used. Results: 254 alarms were triggered, where 11% were attended and 89% presented alarm fatigue, totaling 168 hours of observation. The average number of alarms triggered was 4.5 alarms / day with average user time of 64 seconds. The Nursing Activities Score average was 59.2. An association was evidenced of the alarms attended with the complexity of the patient (P b .05), with an increase of almost 5% in the chance of attendance at each point increase in the value of Nursing Activities Score. It was also estimated that at each point of the Nursing Activities Score, the alarm has a 4% chance of being attended to every second (P b .05). Conclusion: The Nursing Activities Score is directly related to the response time to alarms triggered by multiparameter monitors.

Jornal Vascular Brasileiro, 2019

Resumo A trombose venosa superficial (TVS), também denominada de tromboflebite superficial, carac... more Resumo A trombose venosa superficial (TVS), também denominada de tromboflebite superficial, caracteriza-se pela formação de trombos dentro de veias superficiais, com suboclusão ou oclusão da luz e reação inflamatória no seu trajeto, sendo mais comum nos membros inferiores. Afeta de 3 a 11% da população geral. O diagnóstico costuma ser clinicamente fácil, mas sua extensão e possíveis complicações tromboembólicas precisam de exames subsidiários para confirmação. A TVS pode estar associada a trombose venosa profunda em 6 a 40% dos casos, a embolia pulmonar assintomática (EP) em 20 a 33%, e a EP sintomática em 2 a 13%. Apesar de sua morbidade e das suas complicações, ainda não existem diretrizes brasileiras para a TVS. Nesta diretriz, foram analisadas as principais dúvidas quanto à definição, terminologia e etiologia da TVS, com recomendações para seu diagnóstico e tratamento.

Anais Brasileiros De Dermatologia, Aug 1, 2002

O objetivo do presemte estudo foi avaliar a prevalencia e associacao entre a tromboflebite de rep... more O objetivo do presemte estudo foi avaliar a prevalencia e associacao entre a tromboflebite de repeticao e a deficiencia de antitrombina III. Foram avaliados 42 pacientes que apresentaram tromboflebite superficial de repeticao, sendo 34 do sexo feminino e oito do sexo masculino, com idades variando entre 17 e 60 anos (media de 39,5 anos). A prevalencia maxima de deficiencia de antitrombina III detectada na populacao geral e de um caso para 2.000 estudados. Neste estudo foi usado o metodo coagulometrico para determinar a atividade biologica da antitrombina III. Na analise estatistica empregou-se o metodo da odds ratio com intervalo de confianca 95 por cento p

Cir. vasc. …, 2001

Base de dados : LILACS. Pesquisa : 341940 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 341940 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 341940. ...

J. vasc. bras, 2003

Base de dados : LILACS. Pesquisa : 364746 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 364746 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. Texto completo. experimental, Documentos relacionados. Id: 364746 ...

Angiology, 2011

The occurrence of neoplasms in patients with idiopathic deep vein thrombosis (DVT) may result in ... more The occurrence of neoplasms in patients with idiopathic deep vein thrombosis (DVT) may result in a significant reduction in survival rates. The aim of our study was to assess the use of chest X-rays (CXRs) as a screening method of intrathoracic neoplasms in patients who with idiopathic DVT. In observational, cross-sectional study, the medical records of 99 patients with idiopathic DVT, who were submitted to CXR (during the hospital stay or within 30 days after discharge), were investigated. Of these patients, 15.1% had images suggestive of thoracic neoplasias (single or multiple pulmonary nodules and mediastinal widening). Neoplasms were diagnosed in 4 patients in the follow-up with CXR. The CXR is an option of early screening for thoracic neoplasms and other nonmalignant diseases in patients with idiopathic DVT.

Acta Biomaterialia, 2013

ABSTRACT The use of scaffolds composed of natural biodegradable matrices represents an attractive... more ABSTRACT The use of scaffolds composed of natural biodegradable matrices represents an attractive strategy to circumvent the lack of cell engraftment, a major limitation of stem cell therapy in cardiovascular diseases. Bovine derived non-porous collagen scaffolds with different degrees of cross-linking (C0, C2, C5 and C10) were produced and tested for their mechanical behavior, in vitro biocompatibility with adipose derived stem cells (ADSC) and tissue adhesion and inflammatory reaction. Uniaxial tensile tests revealed an anisotropic behavior of collagen scaffolds (2x0.5cm size) and statistically significant differences in the mechanical behavior between cross-linked and non-cross-linked scaffolds (n=5). In vitro, ADSCs adhered homogenously and showed a similar degree of proliferation on all four types of scaffolds (Cellsx10(3)/cm(2) at day 7: C0:94.7±37.1; C2:91.7±25.6; C5:88.2±6.8; C10:72.8±10.7; p=n.s.; n=3). In order to test the in vivo biocompatibility, a chronic myocardial infarction model was performed in rats and 1.2x1.2cm size collagen scaffolds implanted onto the heart 1month post-infarction. Six animals per group were sacrificed 2, 7 and 30 days after transplant. Complete and long-lasting adhesion to the heart was only observed with the non-cross-linked scaffolds with almost total degradation 1 month post-transplantation. After 7 and 30 days post-implantation, the degree of inflammation was significantly lower in the hearts treated with non-cross-linked scaffolds (Day 7: C0:10.2±2.1%; C2:16.3±2.9%; C5:15.9±4.8%; C10:17.4±4.1%; p<0.05 vs. C0; Day 30: C0:1.3±1.3%; C2:9.4±3.0%; C5:7.0±2.1%; C10:9.8±2.5%; p<0.01 vs. C0). In view of the results, the non-cross-linked scaffold (C0) was chosen as an ADSC-carrier sheet and tested in vivo. One week post-implantation, 25.3±7.0% of the cells transplanted were detected in those animals receiving the cell-carrier sheet whereas no cells were found in animals receiving cells alone (n=3 animals/group). We conclude that the biocompatibility and mechanical properties of the non-cross-linked collagen scaffolds makes them a useful cell carrier that greatly favors tissue cell engraftment and may be exploited for cell transplantation in models of cardiac disease.