Septiani Mangiwa - Academia.edu (original) (raw)

Papers by Septiani Mangiwa

JURNAL BIOLOGI PAPUA

Coffee bean are rich of secondary metabolits that able to inhibit free radical compounds. This an... more Coffee bean are rich of secondary metabolits that able to inhibit free radical compounds. This antioxidant activity may reduce many diseases correlated with it. The aims of this study were to determined the phytochemical content and antioxidant activity of roasted coffee bean from Wamena and Moenemani regency, Papua. Roasted coffee beans were extracted by maceration for 24 hr with methanol. Harborne standard method was used for the phytochemical analysis and DPPH assay was used to determine the antioxidant activity. IC50 was measured by spectrophotometric assay using spectrophotometer Uv-Vis at 517 nm wavelenghth. Result showed that both Arabica roasted coffee beans from Wamena and Moanemany had the capacity to inhibit free radical at 61,71% and 69,7% with IC50 at 107,97 and 100,91 ppm, respectively . Phytochemical investigation revealed that the bioactive compounds from Moanemani and Wamena coffee beans were similar, which composed of alkaloids, flavonoids, terpenoids, saponins...

Rumput laut dapat dimanfaatkan oleh masyarakat sebagai bahan baku dalam industri pangan, farmasi,... more Rumput laut dapat dimanfaatkan oleh masyarakat sebagai bahan baku dalam industri pangan, farmasi, kosmetik dan bioteknologi. Rumput laut juga merupakan bahan baku utama dalam pembuatan agar – agar, alginat dan karaginan. Karaginan merupakan salah satu jenis hidrokoloid yang dapat digunakan untuk memproduksi bioplastik. Pada penelitian ini karaginan digunakan sebagai bahan baku pembuatan bioplastik dengan sorbitol sebagai bahan pemlastis. Penelitian ini bertujuan mengkarakterisasi bioplastik yang dihasilkan dari karaginan rumput laut merah asal Biak dengan sorbitol sebagai pemlastis. Karaginan dicampurkan sorbitol dengan metode blending. Variasi konsentrasi karaginan berturut turut adalah 0,6; 0,8; 1; 1,2 dan 2 %. Variabel yang dianalisis meliputi kuat tarik, perpanjangan, laju transmisi uap air, dan scanning electron microscopy (SEM). Hasil penelitian menunjukkan bahwa ketebalan bioplastik yang dihasilkan berkisar antara 0,025-0,053 mm. Uji SEM memperlihatkan bahwa bioplastik yang d...

Research and Advances in Pharmacy and Life Sciences, 2021

The Itchy leaf [Laportea decumana (Roxb.) Wedd] is a plant that is widely used as traditional med... more The Itchy leaf [Laportea decumana (Roxb.) Wedd] is a plant that is widely used as traditional medicine by Papuans as a pain reliever. The purpose of this study was to determine the total level of alkaloids in itchy leaf extract and to test the cytotoxic activity using the BSLT method. The research series began with the extraction stage with the maceration method using 96% ethanol, which tested the alkaloid level. The test was carried out using the gravimetric method and the cytotoxic test using the alkaloid level test results using the BSLT method on shrimp larvae (Artemia salina L). The results showed that itchy leaf extract contained a total alkaloid level of 6.46%. Cytotoxic testing using the BSLT method showed an LC50 of 54.33 ppm and was found to be toxic.

Free radicals are charged atom or molecules which have an unpaired electron, which causes them to... more Free radicals are charged atom or molecules which have an unpaired electron, which causes them to seek out and capture electrons from other substances in order to neutralize themselves. Ultra violet radiation and heat from sunlight can activate oxygen to produce free radicals which may damage healthy cells of the body, causing them to lose their structure and. Antioxidants are chemical compound that can inhibit free radicals. Mangosteen rind (Gracinia mangostana) have many chemical compounds that have high antioxidative activity from xantone class such as 8-hidroksikudraxanton, gartanin, alpha-mangostin, gamma-mangostin, and smeathxanton A. Likewise with the antioxidant activity of the ethyl acetate extract of noni fruit (Morinda citrifolia) which is comparable to both a- tocopherol and BHT. This study was conducted to measure the antioxidant activity of the combination of extract noni fruit and mangosteen peels. The extract obtained by maceration method , then the combination of ex...

The need for fuel continues to increase along with population growth and development of the times... more The need for fuel continues to increase along with population growth and development of the times. But what happens when this is fossil fuel supplies continue to decline. Therefore, it is necessary to find an alternative that can provide renewable fuels and environmentally friendly. One form of alternative energy that has the prospective to be developed is biogas. Biogas can be obtained by making use of livestock manure. Moreover, in the manufacture of biogas, also produced fertilizer which can be used for plant fertility. Do counseling / guidance and knowledge transfer to the public to utilize the manure waste as biogas instead of wood fuel / kerosene and manure that are environmentally friendly and provide an example to the community about how to make a tool of sewage treatment of livestock manure into biogas as appropriate technology affordable by the public as a form of community service. This event was held for groups of pig farmers in Konya, Village Hedam, Heram District Jayap...

Trigonelline is a one of chemical compound that have activity as antioxidant, anti cancer, anti d... more Trigonelline is a one of chemical compound that have activity as antioxidant, anti cancer, anti diabetes, and estrogenic. The study of determination trigonelline in Arabica coffee beans from Wamena, Jayawijaya regency, Papua have been performed by HPLC method using C-18 column (150 mm length; 4,6 mm in diameter) as the stationary phase while mobile phase consist of metanol : buffer fosfat 10 mM pH 2,6 (30 : 70, v/v) and detector waveleght was set at 265 nm. Trigonelline content was determined in unroasted and roasted (75, 150, 225 0 C) coffee beans. Extraction was performed by soxhletation method using metanol as solvent during five hours. The linearity for concentrations between 100 – 200 ppm trigonelline with correlation coefisien (R 2 = 0,9761). The results showed that trigonelline content of Arabica coffee beans was different for each of temperature roasting, that is 4,70 % for unroasted; 3,76 ; 4, 90 ; dan 3,86 %, for roasted at 75, 150 dan 225 0 C, respectively. The highes...

Kopi merupakan salah satu komoditas unggulan di Papua. Papua memiliki berbagai jenis kopi berkua... more Kopi merupakan salah satu komoditas unggulan di Papua. Papua memiliki berbagai jenis kopi berkualitas yang memiliki cita rasa dan aroma yang khas. Kopi- kopi tersebut tersebar di beberapa wilayah di Papua. Kopi yang berkualitas akan menghasilkan cita rasa, aroma dan khasiat yang berkualitas. Kualitas biji kopi dipengaruhi oleh beberapa faktor, antara lain : jenis, letak geografis, cara pengolahan dan cara penyajian. Umumnya kopi disajikan dalam bentuk minuman yang diolah dari biji kopi sangrai dengan teknik penyeduhan menggunakan metoda ekstraksi menggunakan pelarut air. Pemilihan metoda ekstraksi akan mempengaruhi kualitas ekstrak yang dihasilkan. Penelitian ini bertujuan untuk mengetahui pengaruh metode ekstraksi terhadap sifat fisik dan kimia kopi Papua. Sampel kopi yang digunakan dalam penelitian ini adalah biji kopi Arabika asal Wamena dan Lanny Jaya. Biji kopi diekstraksi dengan metode maserasi dan soxhletasi. Hasil penelitian menunjukkan bahwa semua esktrak biji kopi berwar...

Kopi merupakan minuman yang berasal dari pengolahan biji tanaman kopi dan diyakini berkhasiat bag... more Kopi merupakan minuman yang berasal dari pengolahan biji tanaman kopi dan diyakini berkhasiat bagi tubuh manusia karena mengandung berbagai komponen kimia. Secara umum kopi mengandung senyawa kimia aktif berupa alkaloid, saponin, flavonoid dan polifenol. Kafein adalah salah satu senyawa kimia aktif golongan alkaloid yang terdapat di dalam biji kopi. Biji kopi juga mengandung asam klorogenat yang merupakan salah satu senyawa golongan polifenol yang berperan sebagai antioksidan. Kafein dan asam klorogenat terdapat dalam biji kopi dalam biji kopi dalam jumlah yang cukup banyak terutama dalam biji kopi hjiau. Dewasa ini, kajian mengenai biji kopi hijau dan kandungan senyawa kimia yang terdapat di dalamnya banyak menjadi perhatian para peneliti, khususnya bagi keperluan analisis kontrol kualitas. Untuk analisis kontrol kualitas, diperlukan suatu standar reference material yang sesuai. Namun standar reference material cenderung mahal dan sulit diperoleh. Oleh karena itu, pada penelitian i...

International Journal of Research in Engineering and Technology, 2018

The teaching and learning process in junior high schools in Papua, still conventional, is that te... more The teaching and learning process in junior high schools in Papua, still conventional, is that teachers deliver subject matter, assignments, quizzes, gathering assignments and other things related to the teaching and learning process are only carried out in the classroom so that learning activities are limited by time according to hours lesson. This resulted in the achievement of competence, completeness of the subject matter, and students' learning motivation was not achieved. Smart solutions to deal with problems in junior high schools in Papua is to make smart school applications. Smart school applications become blended learning that combines advance learning methods with online learning systems .Increasing student learning motivation by implementing a smart school application can form interactions between teachers and students, students and students, and communication between the school and parents. This can create an effective, efficient and paperless learning environment.

The aim of this research was to determine biodegradability of bioplastic making of Caraageenan. T... more The aim of this research was to determine biodegradability of bioplastic making of Caraageenan. The carrageenan extracted from red seaweed from Biak island. Variables analyzed in this research were the water content, the weight decreasing, solubility in water and colour. Research showed that caragenaan bioplastic was soluble in water. It is very degradable in soil. In room temperature, bioplastic was relatively slow in degradation process. Keywords : carrageenan, bioplastic, degradability

Hydrogen: Jurnal Kependidikan Kimia

Chlorogenic acid (CGA) is one of chemical compound in coffee and class of polyphenolic compounds ... more Chlorogenic acid (CGA) is one of chemical compound in coffee and class of polyphenolic compounds that have activity as antioxidant. This study aims to determine the CGA contain in Arabica coffee beans from Wamena regency of Jayawijaya, Papua. Coffee beans were roasted by three roasting temperature i.e. 75, 150 and 2250 C while unroasted one was used as controls. Extraction was performed by soxhletation using metanol as a solvent for 5 hours. Separation and CGAcontent were determined using HPLC uses C-18 column, 150 mm length, 4,6 mm in diameter, with metanol-fosfat buffer 10 mM pH 2,6(30:70) as eluent, flow rate of 1 mL/minutes, injection volume of 20 µL and measured by spectrophotometer UV-Vis in 329 nm. The result of the study shows the CGAcontent in treated beans with temperature roasting of 75, 150 and 2250C respectively were 6,93 ; 9,33 and 7,12 % while the unroasted one was 7,73 %. The lowest CGA content was found in coffee beans roasted in 750C while the highest in 15...

JURNAL BIOLOGI PAPUA

Research and Advances in Pharmacy and Life Sciences, 2021

International Journal of Research in Engineering and Technology, 2018

Hydrogen: Jurnal Kependidikan Kimia