Sergio Borin - Academia.edu (original) (raw)

Papers by Sergio Borin

Background: We considered both the indiscriminate use of steroids by top athletes and by physical... more Background: We considered both the indiscriminate use of steroids by top athletes and by physically active individuals. Objective: To evaluate the effects of nandrolone decanoate on the electrocardiographic profile, glycogen content and total-protein profile of skeletal and cardiac muscles, as well as the plasma albumin concentrations. Methods: The drug was administered subcutaneously, at a concentration of 5 mg/kg, twice a week for three weeks, to animals in the treated group. Once a week, the rats were anesthetized with sodium pentobarbital (50 mg/kg, ip) and they underwent an electrocardiogram (ECG). After the trial period, samples of the cardiac muscle (left ventricle- LV), soleus muscle (S), white gastrocnemius muscle (WG), red gastrocnemius muscle (RG), pectoral muscle (P), intercostal muscle (IC) and diaphragm muscle (D) were promptly collected and analyzed. An analysis of variance (ANOVA) and then a Tukey test (p>0.05) were carried out to assess the data (mean ± sem). Res...

1Methodist University of Piracicaba-Masters Course in Physical Education; 2Masters course in Phys... more 1Methodist University of Piracicaba-Masters Course in Physical Education; 2Masters course in Physiotherapy; 3Physioterapist of the Rehabilitation Center of the Municipal Prefecture of Rio das Pedras-SP, Brazil; 4Physiological Sciences Department, Exercise Physiology Laboratory, Federal University of Sao Carlos, Sao Paulo, Brazil; 5Integration Faculty of Tiete-SP, Brazil; 6University Center of UNIRG, Tocantis-TO, Brazil; 7Anhanguera University Center– UNIFIAN – Leme-SP, Brazil. E-mail: coassumpcao@yahoo.com.br

Effect of different dose of leucine on glycogen reserves from denervated skeletal muscle of rats

The aim of this study was to investigate the action of different doses of leucine on the dynamics... more The aim of this study was to investigate the action of different doses of leucine on the dynamics of glycogen reserves of denervated skeletal muscle of rats. Wistar rats aged 3 to 4 months, weighing between 200 and 300g being kept under controlled conditions Biotery. The animals were divided into experimental group called control (C), denervated (D) treated with amino acid leucine in three doses 5nm(CL5), 1.25 mM (CL1,25) and 0.30mM(CL0,30), denervated treated with 0.30mM(DL0,30). Supplementation was performed by gavage and denervation was performed by sectioning the sciatic nerve. The analysis of the content of glycogen was performed on samples of the soleus(S), gastrocnemius white(GW) and red(GR). The muscle was lower in S glycogen (-33% and -42,8%), both in CL1,25 and CL5 and increased in a dose CL0,30(+38%), possibly due to act upon this low dose of insulin secretagogue, promoting an increase in the rate of glucose uptake by peripheral tissues (11,2± 0,3%/min C x 14,16 ± 0,2%/mi...

Revista Brasileira de Nutrição Esportiva, 2011

The mannering standard of rats supplemented with amino acid leucine Supplementation with branched... more The mannering standard of rats supplemented with amino acid leucine Supplementation with branched chain amino acids has been disseminated widely among practitioners of physical activities. Studies suggest the development of central fatigue during activity, its correlation brain serotonin and leucine. Purpose of this study was to evaluate through tests of open field and elevated plus-maze, the behavior of rats supplemented with three different doses of leucine. Wistar rats were divided into groups: control (C), leucine 0.30mM/100g (L0,30), 1.25mM/100g (L1,25) and 5mM/100g (L5), supplemented via oral gavage. For statistical analysis, variance followed by Tukey test (p<0.05). The exploratory behavior was observed that rats L0,30 did not differ from C and the groups L1,25 and L5, showed a reduction. In the elevated plus-maze group C compared with L0,30 and L1,25 did not get the difference, the L5 group differed from the others. The results suggest the existence of physiological and behavioral changes related to supplementation with leucine.

Resumen en: The purpose of this study was analyze the effects of strength training on quadriceps ... more Resumen en: The purpose of this study was analyze the effects of strength training on quadriceps muscle electromyographic activity and lower limb power in elderly wo...

Revista Brasileira de Ciências do Esporte, 2016

Treinamento anaeróbio; Ratos idosos; Metabolismo; Glicogênio Resumo A proposta deste estudo foi a... more Treinamento anaeróbio; Ratos idosos; Metabolismo; Glicogênio Resumo A proposta deste estudo foi avaliar o comportamento das reservas glicogênicas de músculos do membro anterior e posterior, além de ajustes metabólicos em ratos envelhecidos submetidos a treinamento anaeróbio. Foram usados ratos Wistar com 18 meses divididos em dois grupos experimentais (n = 10), controle (C) e treinamento anaeróbio (Tana). Após o treinamento, os ratos foram anestesiados e amostras de sangue e músculos coletadas e enviadas para avaliação bioquímica. Os dados mostram maiores reservas glicogênicas no grupo Tana e indicam supercompensação com efeito predominante na musculatura dos membros posteriores; foram observados menor peso corporal e maior peso das adrenais acompanhado de maiores concentrações plasmáticas de proteínas totais. O conjunto de dados indicam que Tana propicia melhoria na homeostasia metabólica e na qualidade de vida.

Escolha De Enxerto Patelar X Semitendíneo/Grácil Na Reconstrução De Lesão De Ligamento Cruzado Anterior Em Atletas - Uma Revisão Bibliográfica

Revista Brasileira de Medicina do Esporte, 2014

INTRODUÇÃO: Entre os suplementos utilizados no meio esportivo, o mineral cromo tem se destacado, ... more INTRODUÇÃO: Entre os suplementos utilizados no meio esportivo, o mineral cromo tem se destacado, principalmente por potencializar a ação da via insulínica, ação extremamente importante na manutenção da homeostasia metabólica. A ação do cromo parece ter ação importante como coadjuvante nas dinâmicas da ação insulínica.OBJETIVO: Avaliar o perfil glicogênico, bem como a sensibilidade tecidual à insulina e a pancreática à glicose em ratos jovens e envelhecidos tratados com picolinato de cromo.MÉTODO: Foram utilizados ratos Wistar, com idade de 3 e 24 meses, distribuídos em quatro grupos experimentais (n = 6), assim denominados: jovens (J), jovens suplementados com picolinato de cromo (JP, 80 µg/Kg), envelhecidos (E) e envelhecidos suplementados com picolinato de cromo (EP, 80 µg/Kg). A sensibilidade à insulina foi avaliada através do teste de tolerância à insulina (ITT, 2 U/Kg) e a sensibilidade pancreática, através do teste de tolerância à glicose (GTT, 2 g/Kg). Na análise estatística ...

Medicina (Ribeirao Preto. Online), 2012

O objetivo do estudo foi investigar o efeito de diferentes doses de leucina sobre as reservas gli... more O objetivo do estudo foi investigar o efeito de diferentes doses de leucina sobre as reservas glicogênicasdo músculo esquelético de ratos desnervados. Foram utilizados 36 ratos Wistar com 3 a 4 meses,pesando entre 200 e 300g sendo mantidos em condições controladas de bioterismo. Os animais foramdistribuídos em grupo experimentais denominados controle(C); desnervados(D); tratados comaminoácido leucina em três doses 5mM(CL5); 1,25mM(CL1,25) e 0,30mM(CL0,30); desnervado tratadocom 0,30mM(DL0,30). A suplementação da leucina foi feita por gavagem e a desnervação foi realizadapela secção do nervo isquiático. As análises do conteúdo de glicogênio foram realizadas em amostrasdos músculos sóleo(S), gastrocnemio branco(GB) e vermelho(GV). O músculo S apresentou reduçãono glicogênio tanto em CL5(-42,8%) quanto em CL1,25(-33%) e aumento na dose CL0,30(+38%). Épossível que a baixas doses de leucina tenham estimulado a secreção de insulina, promovendo aumento na velocidade de captação de glicose ...

RBNE-Revista Brasileira de …, 2012

RBNE - Revista Brasileira de Nutrição Esportiva. ...

Análise da atividade eletromiográfica dos músculos do tornozelo em solo estável e instável; Electromyography activity analysis of the ankle muscles at the stable and …

Fisioter. mov, 2009

Base de dados : LILACS. Pesquisa : 543473 [Identificador único]. Referências encontradas : 1 [ref... more Base de dados : LILACS. Pesquisa : 543473 [Identificador único]. Referências encontradas : 1 [refinar]. Mostrando: 1 .. 1 no formato [Detalhado]. página 1 de 1, 1 / 1, LILACS, seleciona. para imprimir. Fotocópia. experimental, Documentos relacionados. Id: 543473. ...

Arquivos Brasileiros de Cardiologia, 2010

Objective: To evaluate the effects of nandrolone decanoate on the electrocardiographic profile, g... more Objective: To evaluate the effects of nandrolone decanoate on the electrocardiographic profile, glycogen content and total-protein profile of skeletal and cardiac muscles, as well as the plasma albumin concentrations. Methods: The drug was administered subcutaneously, at a concentration of 5 mg/kg, twice a week for three weeks, to animals in the treated group. Once a week, the rats were anesthetized with sodium pentobarbital (50 mg/kg, ip) and they underwent an electrocardiogram (ECG). After the trial period, samples of the cardiac muscle (left ventricle -LV), soleus muscle (S), white gastrocnemius muscle (WG), red gastrocnemius muscle (RG), pectoral muscle (P), intercostal muscle (IC) and diaphragm muscle (D) were promptly collected and analyzed. An analysis of variance (ANOVA) and then a Tukey test (p>0.05) were carried out to assess the data (mean ± sem). Results: There were changes in the following parameters of rats in the treated group: QRS interval, QTc interval and heart rate, characterized by an increase in these parameters, with the peak being reached in the period between the pre-treatment week and the first week. There was an increase of 127% in glycogen reserves in the LV. In relation to the total-protein amount, the significant difference was found in S, RG and D. As for the hematocrit and biochemical profile, it was possible to notice an increase in the percentage of erythrocytes. The study shows that major cardiac changes are triggered at an early stage, which indicates a hierarchy in the sequence of changes that compromise the homeostasis of the body. (Arq Bras Cardiol 2010;95(6):720-725

The purpose of this study was analyze the effects of strength training on quadriceps muscle elect... more The purpose of this study was analyze the effects of strength training on quadriceps muscle electromyographic activity and lower limb power in elderly women. 28 female volunteers aged 65.5 ± 3.6 years old were submitted to strength training for 12 weeks with a frequency of twice a week and were divided into: G1P (n=16, periodized group) and G2NP (n=12, non-periodized group). Electromyographic activity of vastus medialis oblique (VMO), vastus lateralis longus (VLL), oblique (VLO), rectus femoris (RF) muscles in knee extension movement, root mean square (RMS), median frequency (MF) were determined and lower limb power was analyzed by the jump test. There was an increase of RMS in the 30º knee flexion angle in

Revista Brasileira De Prescricao E Fisiologia Do Exercicio, 2011