Serhan Boduroglu - Academia.edu (original) (raw)
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Papers by Serhan Boduroglu
Immobilization of proteins on polymer surfaces is of great interest for applications in biosensin... more Immobilization of proteins on polymer surfaces is of great interest for applications in biosensing, cell and tissue culturing, and medical device coating. This research studied the functionalization of a fluorescent protein on a structured polymer surface. Copolymerization of 4-trifluoroacetyl-(2.2)paracyclophane and 4-amino-(2.2)paracyclophane by a vapor deposition technique result in the formation of slanted, columnar, porous structures of the copolymer poly(o-trifluoroacetyl- p- xylylene-co-o-amino-p-xylylene-co-p-xylylene), (PPX-COCF3-NH2). The coupling of green fluorescent protein (GFP) to the structured and planar (control) polymer surfaces was studied by chemisorption (i.e. using a linking reagent, hexamethylene diisocyanate (HMDI)) and physisorption (i.e. without any linker). The fluorescence intensity of GFP on the surfaces was measured by an optical microscope and the data was analyzed using imaging software. The fluorescence intensity on the structured surfaces was higher...
Polymer, 2007
Nanostructured thin films of poly(p-xylylene) derivatives are deposited by oblique angle vapor de... more Nanostructured thin films of poly(p-xylylene) derivatives are deposited by oblique angle vapor deposition method under low-vacuum conditions. We showed deposition of columnar nanostructured poly(o-chloro-p-xylylene) and poly(o-bromo-p-xylylene) thin films, and co-deposition of nanostructured poly(o-trifluoroacetyl-p-xylylene-cop -xylylene) thin film. Characterization of both the nanostructured and planar thin films of poly(p-xylylene) are performed with different experimental methods. We developed a generalized strategy towards depositing nanostructured poly(p-xylylene) derivatives and thus promise a new generation of thin films suitable for biomedical and antifouling applications.
Langmuir, 2007
Thin films of poly(chloro-p-xylylene) (PPXC) grown by the pyrolysis and evaporation of chloro-[2.... more Thin films of poly(chloro-p-xylylene) (PPXC) grown by the pyrolysis and evaporation of chloro-[2.2]paracyclophane in an evacuated chamber contain free-standing, slanted, parallel columns that are 50 µm long and are assemblies of 50-to 100-nm-diameter nanowires, which thus can have an unprecedented aspect ratio as high as 1000:1. The nanostructured thin films organize spatially with a chemical structure similar to that of planar PPXC thin films, but the former also possess nanostructured morphology. Nanostructured thin films of poly(p-xylylene) (PPX) and its derivatives shall be useful as functionalized interfaces for antifouling coatings and biomedical devices.
Langmuir, 2007
The hydrophobic surface properties of structured poly-(p-xylylene) (PPX) films, as measured by wa... more The hydrophobic surface properties of structured poly-(p-xylylene) (PPX) films, as measured by water wettability, are studied as functions of surface chemistry, film composition, and surface roughness. We demonstrate the fabrication of very hydrophobic surfaces and control over adhesion properties via nanoscale modulation of roughness, changes in composition, and alteration of the surface chemistry of PPX films. The formation of superhydrophobic surfaces through the chemisorption of fluoroalkylsiloxane coatings to hydroxyl sites created on the nanostructured PPX surface is also illustrated. The ability to control both hydrophobicity and adhesion using nanostructured PPX films is a promising development because it may lead to a new generation of coatings with applicability ranging from selfcleaning surfaces to robotics.
Immobilization of proteins on polymer surfaces is of great interest for applications in biosensin... more Immobilization of proteins on polymer surfaces is of great interest for applications in biosensing, cell and tissue culturing, and medical device coating. This research studied the functionalization of a fluorescent protein on a structured polymer surface. Copolymerization of 4-trifluoroacetyl-(2.2)paracyclophane and 4-amino-(2.2)paracyclophane by a vapor deposition technique result in the formation of slanted, columnar, porous structures of the copolymer poly(o-trifluoroacetyl- p- xylylene-co-o-amino-p-xylylene-co-p-xylylene), (PPX-COCF3-NH2). The coupling of green fluorescent protein (GFP) to the structured and planar (control) polymer surfaces was studied by chemisorption (i.e. using a linking reagent, hexamethylene diisocyanate (HMDI)) and physisorption (i.e. without any linker). The fluorescence intensity of GFP on the surfaces was measured by an optical microscope and the data was analyzed using imaging software. The fluorescence intensity on the structured surfaces was higher...
Polymer, 2007
Nanostructured thin films of poly(p-xylylene) derivatives are deposited by oblique angle vapor de... more Nanostructured thin films of poly(p-xylylene) derivatives are deposited by oblique angle vapor deposition method under low-vacuum conditions. We showed deposition of columnar nanostructured poly(o-chloro-p-xylylene) and poly(o-bromo-p-xylylene) thin films, and co-deposition of nanostructured poly(o-trifluoroacetyl-p-xylylene-cop -xylylene) thin film. Characterization of both the nanostructured and planar thin films of poly(p-xylylene) are performed with different experimental methods. We developed a generalized strategy towards depositing nanostructured poly(p-xylylene) derivatives and thus promise a new generation of thin films suitable for biomedical and antifouling applications.
Langmuir, 2007
Thin films of poly(chloro-p-xylylene) (PPXC) grown by the pyrolysis and evaporation of chloro-[2.... more Thin films of poly(chloro-p-xylylene) (PPXC) grown by the pyrolysis and evaporation of chloro-[2.2]paracyclophane in an evacuated chamber contain free-standing, slanted, parallel columns that are 50 µm long and are assemblies of 50-to 100-nm-diameter nanowires, which thus can have an unprecedented aspect ratio as high as 1000:1. The nanostructured thin films organize spatially with a chemical structure similar to that of planar PPXC thin films, but the former also possess nanostructured morphology. Nanostructured thin films of poly(p-xylylene) (PPX) and its derivatives shall be useful as functionalized interfaces for antifouling coatings and biomedical devices.
Langmuir, 2007
The hydrophobic surface properties of structured poly-(p-xylylene) (PPX) films, as measured by wa... more The hydrophobic surface properties of structured poly-(p-xylylene) (PPX) films, as measured by water wettability, are studied as functions of surface chemistry, film composition, and surface roughness. We demonstrate the fabrication of very hydrophobic surfaces and control over adhesion properties via nanoscale modulation of roughness, changes in composition, and alteration of the surface chemistry of PPX films. The formation of superhydrophobic surfaces through the chemisorption of fluoroalkylsiloxane coatings to hydroxyl sites created on the nanostructured PPX surface is also illustrated. The ability to control both hydrophobicity and adhesion using nanostructured PPX films is a promising development because it may lead to a new generation of coatings with applicability ranging from selfcleaning surfaces to robotics.