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Research paper thumbnail of The Importance of Prolactin Levels in Patients Treated with Cabergoline for the Prevention of OHSS: Is Cabergoline Really Effective in Patients with High Risk of OHSS?

Background: OHSS is a dangerous and potentially life-threatening condition for which many researc... more Background: OHSS is a dangerous and potentially life-threatening condition for which many researchers look for new ways to treat. Aim: To determine the effectiveness of prophylactic cabergoline administration on prolactine levels in patients with high risk for ovarian hyperstimulation syndrome (OHSS). Material and Methods: 163 in vitro fertilisation (IVF) patients with high risk for OHSS were enrolled in the study. The criteria for inclusion were more than 15 oocytes retrieved at oocyte pick up. A standard antagonist protocol was used for ovulation induction. Cabergoline treatments (0.5 mg/day) were started on the day of oocyte retrieval and continued for eight days. Prolactine levels were measured at the day of oocyte retrieval and the 9th day after the oocyte retrieval. Results: Of the 163 patients, 26 (15.9%) had OHSS. Prolactine levels on the day of oocyte retrieval were 44.22 ± 24.78 ng/mL and 37.6 ± 22.5 ng/mL in patients with OHSS and without OHSS, respectively (P > 0.05). In contrary prolactine levels were significantly higher in patients with OHSS patients (3.9 ± 5.07 ng/mL) than in patients without OHSS (2.1 ± 2.92 ng/mL) at the 9th day after oocyte retrieval (P < 0.05). Conclusion: Prolactine levels were higher in patients with OHSS than without OHSS who were treated with cabergoline for the prevention of OHSS.

Papers by Serkan Oral

Research paper thumbnail of Sağlık Alanında Bilimsel Makale Nasıl Yazılır

Gunumuzde ortalama yasam suresinin, Orta Cag’da yasayanlarin iki katindan fazla olmasinin ana ned... more Gunumuzde ortalama yasam suresinin, Orta Cag’da yasayanlarin iki katindan fazla olmasinin ana nedeni bilimsel calismalarin insanliga yaptigi katkidir. Bu calismalar sayesinde bizden once yasayanlardan daha uzun bir hayat surmekteyiz. Bilimin gelisimi ve insan yararina kullanimi, yapilan calismalarin yaziya dokulmesi, baskalari tarafindan okunmasi, anlasilmasi, tartisilmasi ve uygulanmasiyla baslamistir. Gunluk pratigimizde kullandigimiz tani yontemleri, uygulamalar ve ilaclar, yillarca suren calismalarin sonuclarina gore sekillenmistir. Bunun devamliligini saglamak icin, saglik alaninda calisanlar sorgulamaci ve arastirmaci olmalidir.Yillardir kullanilan yontemler de dahil tum uygulamalara sorgulayan gozle bakmak, daha iyisi icin arastirma yapmak mesleki gelisime buyuk katki saglayacaktir. Şasirtici olarak, uzun zamandir klinik pratikte var olan bazi yaklasimlar bile cok az sayida dogru duzenlenmis calismaya dayalidir.

Research paper thumbnail of Diagnosis and management of iatrogenic ureteral injury in total laparoscopic hysterectomy

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Ureteral injury is common in gynecological surgeries due to the proximity to organs. The risk of ... more Ureteral injury is common in gynecological surgeries due to the proximity to organs. The risk of ureteral injury is higher in laparoscopic hysterectomy operations compared to abdominal or vaginal hysterectomies. Obesity, endometriosis, pelvic adhesions, history of previous surgery, enlarged uterus, and intraoperative hemorrhage are some of the risk factors identified for ureteral injury. Intraoperative cystoscopy and postoperative urinary ultrasonography can be used in the diagnosis of early ureteral injury. Management of ureteral injury differs according to the extent, type, and localization of the injury. In evaluating the ureteral injury, early diagnosis and early repair in appropriate patients are essential in morbidity and medicolegal.

Research paper thumbnail of Live birth rate with double ovarian stimulation is superior to follicular phase ovarian stimulation per started cycle in poor ovarian responders

Journal of Obstetrics and Gynaecology Research

Research paper thumbnail of Evaluation of obstructive sleep apnea prevalence in mothers of infants with low birth weight and its relationship with serum uric acid levels as a hypoxia marker

The Journal of Maternal-Fetal & Neonatal Medicine

Research paper thumbnail of Pregnancy results after fresh embryo transfer and selective frozen-thawed embryo transfer: Single-center experience

Journal of Gynecology Obstetrics and Human Reproduction

Research paper thumbnail of Effect of vaginal cleansing on postoperative factors in elective caesarean sections: a prospective, randomised controlled trial

The Journal of Maternal-Fetal & Neonatal Medicine, 2016

To assess the effect of povidone iodine versus benzalkonium chloride, which were applied preopera... more To assess the effect of povidone iodine versus benzalkonium chloride, which were applied preoperatively for vaginal disinfection in caesarean sections, on postoperative factors. One hundred and twenty patients underwent elective caesarean section were divided into three groups using the simple randomisation method: Group 1 (povidone iodine, n: 41); Group 2 (benzalkonium chloride, n: 39); Group 3 (control group, n: 40). Demographic data, duration of operation, amount of bleeding, postoperative pain, time to first flatulence and defaecation, haematological parameters on postoperative day 1 were compared between three groups. Pain evaluation was performed at 6th and 24th postoperative hour using Visual Analogue Scale. No statistically significant differences were detected between the groups in demographic characteristics. There were no significant differences between the groups with respect to the duration of operation and hospital stay. The patients in the group who underwent povidone iodine vaginal cleansing had statistically significantly less postoperative pain as compared to control group. No difference was observed between the groups in haematological parameters other than C-reactive protein (CRP); however, CRP levels at 24th post-operative hour were significantly lower in Group 1 compared to the other groups. The preoperative vaginal cleansing with povidone iodine could reduce the postoperative pain, analgesic need and infection parameter.

Research paper thumbnail of Development and management of ovarian hyperstimulation syndrome in spontaneous singleton pregnancy

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Ovarian hyperstimulation syndrome (OHSS) is one of the most life-threatening complications of ovu... more Ovarian hyperstimulation syndrome (OHSS) is one of the most life-threatening complications of ovulation induction. However, rarely, OHSS can develop spontaneously during pregnancy without induction of ovulation. It has been shown in the literature that some diseases such as polycystic ovary syndrome (PCOS), hypothyroidism, and pituitary adenoma may accompany spontaneous OHSS. Spontaneous OHSS should be included in the differential diagnosis in first-trimester pregnancies with nausea, vomiting, and acute abdomen. The focus should be on preventing possible complications and initiating early treatment immediately after diagnosis.

Research paper thumbnail of The Importance of Prolactin Levels in Patients Treated with Cabergoline for the Prevention of OHSS: Is Cabergoline Really Effective in Patients with High Risk of OHSS?

Background: OHSS is a dangerous and potentially life-threatening condition for which many researc... more Background: OHSS is a dangerous and potentially life-threatening condition for which many researchers look for new ways to treat. Aim: To determine the effectiveness of prophylactic cabergoline administration on prolactine levels in patients with high risk for ovarian hyperstimulation syndrome (OHSS). Material and Methods: 163 in vitro fertilisation (IVF) patients with high risk for OHSS were enrolled in the study. The criteria for inclusion were more than 15 oocytes retrieved at oocyte pick up. A standard antagonist protocol was used for ovulation induction. Cabergoline treatments (0.5 mg/day) were started on the day of oocyte retrieval and continued for eight days. Prolactine levels were measured at the day of oocyte retrieval and the 9th day after the oocyte retrieval. Results: Of the 163 patients, 26 (15.9%) had OHSS. Prolactine levels on the day of oocyte retrieval were 44.22 ± 24.78 ng/mL and 37.6 ± 22.5 ng/mL in patients with OHSS and without OHSS, respectively (P > 0.05). In contrary prolactine levels were significantly higher in patients with OHSS patients (3.9 ± 5.07 ng/mL) than in patients without OHSS (2.1 ± 2.92 ng/mL) at the 9th day after oocyte retrieval (P < 0.05). Conclusion: Prolactine levels were higher in patients with OHSS than without OHSS who were treated with cabergoline for the prevention of OHSS.

Research paper thumbnail of Sağlık Alanında Bilimsel Makale Nasıl Yazılır

Gunumuzde ortalama yasam suresinin, Orta Cag’da yasayanlarin iki katindan fazla olmasinin ana ned... more Gunumuzde ortalama yasam suresinin, Orta Cag’da yasayanlarin iki katindan fazla olmasinin ana nedeni bilimsel calismalarin insanliga yaptigi katkidir. Bu calismalar sayesinde bizden once yasayanlardan daha uzun bir hayat surmekteyiz. Bilimin gelisimi ve insan yararina kullanimi, yapilan calismalarin yaziya dokulmesi, baskalari tarafindan okunmasi, anlasilmasi, tartisilmasi ve uygulanmasiyla baslamistir. Gunluk pratigimizde kullandigimiz tani yontemleri, uygulamalar ve ilaclar, yillarca suren calismalarin sonuclarina gore sekillenmistir. Bunun devamliligini saglamak icin, saglik alaninda calisanlar sorgulamaci ve arastirmaci olmalidir.Yillardir kullanilan yontemler de dahil tum uygulamalara sorgulayan gozle bakmak, daha iyisi icin arastirma yapmak mesleki gelisime buyuk katki saglayacaktir. Şasirtici olarak, uzun zamandir klinik pratikte var olan bazi yaklasimlar bile cok az sayida dogru duzenlenmis calismaya dayalidir.

Research paper thumbnail of Diagnosis and management of iatrogenic ureteral injury in total laparoscopic hysterectomy

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Ureteral injury is common in gynecological surgeries due to the proximity to organs. The risk of ... more Ureteral injury is common in gynecological surgeries due to the proximity to organs. The risk of ureteral injury is higher in laparoscopic hysterectomy operations compared to abdominal or vaginal hysterectomies. Obesity, endometriosis, pelvic adhesions, history of previous surgery, enlarged uterus, and intraoperative hemorrhage are some of the risk factors identified for ureteral injury. Intraoperative cystoscopy and postoperative urinary ultrasonography can be used in the diagnosis of early ureteral injury. Management of ureteral injury differs according to the extent, type, and localization of the injury. In evaluating the ureteral injury, early diagnosis and early repair in appropriate patients are essential in morbidity and medicolegal.

Research paper thumbnail of Live birth rate with double ovarian stimulation is superior to follicular phase ovarian stimulation per started cycle in poor ovarian responders

Journal of Obstetrics and Gynaecology Research

Research paper thumbnail of Evaluation of obstructive sleep apnea prevalence in mothers of infants with low birth weight and its relationship with serum uric acid levels as a hypoxia marker

The Journal of Maternal-Fetal & Neonatal Medicine

Research paper thumbnail of Pregnancy results after fresh embryo transfer and selective frozen-thawed embryo transfer: Single-center experience

Journal of Gynecology Obstetrics and Human Reproduction

Research paper thumbnail of Effect of vaginal cleansing on postoperative factors in elective caesarean sections: a prospective, randomised controlled trial

The Journal of Maternal-Fetal & Neonatal Medicine, 2016

To assess the effect of povidone iodine versus benzalkonium chloride, which were applied preopera... more To assess the effect of povidone iodine versus benzalkonium chloride, which were applied preoperatively for vaginal disinfection in caesarean sections, on postoperative factors. One hundred and twenty patients underwent elective caesarean section were divided into three groups using the simple randomisation method: Group 1 (povidone iodine, n: 41); Group 2 (benzalkonium chloride, n: 39); Group 3 (control group, n: 40). Demographic data, duration of operation, amount of bleeding, postoperative pain, time to first flatulence and defaecation, haematological parameters on postoperative day 1 were compared between three groups. Pain evaluation was performed at 6th and 24th postoperative hour using Visual Analogue Scale. No statistically significant differences were detected between the groups in demographic characteristics. There were no significant differences between the groups with respect to the duration of operation and hospital stay. The patients in the group who underwent povidone iodine vaginal cleansing had statistically significantly less postoperative pain as compared to control group. No difference was observed between the groups in haematological parameters other than C-reactive protein (CRP); however, CRP levels at 24th post-operative hour were significantly lower in Group 1 compared to the other groups. The preoperative vaginal cleansing with povidone iodine could reduce the postoperative pain, analgesic need and infection parameter.

Research paper thumbnail of Development and management of ovarian hyperstimulation syndrome in spontaneous singleton pregnancy

International Journal of Reproduction, Contraception, Obstetrics and Gynecology

Ovarian hyperstimulation syndrome (OHSS) is one of the most life-threatening complications of ovu... more Ovarian hyperstimulation syndrome (OHSS) is one of the most life-threatening complications of ovulation induction. However, rarely, OHSS can develop spontaneously during pregnancy without induction of ovulation. It has been shown in the literature that some diseases such as polycystic ovary syndrome (PCOS), hypothyroidism, and pituitary adenoma may accompany spontaneous OHSS. Spontaneous OHSS should be included in the differential diagnosis in first-trimester pregnancies with nausea, vomiting, and acute abdomen. The focus should be on preventing possible complications and initiating early treatment immediately after diagnosis.