Shadab Jawed - Academia.edu (original) (raw)
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Papers by Shadab Jawed
Zenodo (CERN European Organization for Nuclear Research), Jan 25, 2020
The Madagascar periwinkle plant has shown various promising anticancer properties. Various compou... more The Madagascar periwinkle plant has shown various promising anticancer properties. Various compounds such as alkaloids known to exhibit anti-cancer activity viz. Vinblastine, Vincristine, Vindesine and Vinorelbine, which has been extracted from the periwinkle plants. These drugs are studied for their inhibiting property that slows down microtubule formation in cancer cells therefore highly effective in slowing down the growth of tumors. Vinblastine is used experimentally for treatment of neoplasmas and is recommended for Hodgkins disease. Vincristine another form of alkaloids is used for treating leukemia in children. Therefore, the Madagascar periwinkle is also called a miracle plant in the prevention of childhood leukemia and cancer treatment. In this paper, a systematic study for detecting the alkaloids, isolating the alkaloids in higher yields and characterizing them by various physio-chemical methods have been presented. Emphasis have been given in estimating the concentration of alkaloids viz. Vinblastine and Vincristine in higher yields which are known for its medicinal value in the treatment of cancer.
Earth Science Research
Crystalline minerals in granite rocks has been quantatively analysed by powder X-ray diffraction ... more Crystalline minerals in granite rocks has been quantatively analysed by powder X-ray diffraction (XRD) and Scanning Electron Microscope supported with Energy Dispersed Spectroscopy (SEM-EDS). SEM microphotograph reveals that rock is dominated by brightly illuminated quartz imbedded in the matrix with mica and other minor minerals. The X-ray mineral composition data have been plotted with SEM-EDS mineral composition, data shows that the composition obtained by two technique are in consistent within the experimental limit and in good agreement. Further plot of chemical composition of constituent oxides of granite sample by XRD and SEM-EDS confirm the consistency of two technique and similarity with Jharkhand mean granite composition. Silica composition have been plotted with trace element Pb, Ba, Zr, Rb, and Alumina composition with Pb , Ba, Zr and Rb shows that these elements are randomly imbedded in the matrix with almost uniform composition. Al2O 3 composition have been plotted wit...
Zenodo (CERN European Organization for Nuclear Research), Jan 25, 2020
The Madagascar periwinkle plant has shown various promising anticancer properties. Various compou... more The Madagascar periwinkle plant has shown various promising anticancer properties. Various compounds such as alkaloids known to exhibit anti-cancer activity viz. Vinblastine, Vincristine, Vindesine and Vinorelbine, which has been extracted from the periwinkle plants. These drugs are studied for their inhibiting property that slows down microtubule formation in cancer cells therefore highly effective in slowing down the growth of tumors. Vinblastine is used experimentally for treatment of neoplasmas and is recommended for Hodgkins disease. Vincristine another form of alkaloids is used for treating leukemia in children. Therefore, the Madagascar periwinkle is also called a miracle plant in the prevention of childhood leukemia and cancer treatment. In this paper, a systematic study for detecting the alkaloids, isolating the alkaloids in higher yields and characterizing them by various physio-chemical methods have been presented. Emphasis have been given in estimating the concentration of alkaloids viz. Vinblastine and Vincristine in higher yields which are known for its medicinal value in the treatment of cancer.
Earth Science Research
Crystalline minerals in granite rocks has been quantatively analysed by powder X-ray diffraction ... more Crystalline minerals in granite rocks has been quantatively analysed by powder X-ray diffraction (XRD) and Scanning Electron Microscope supported with Energy Dispersed Spectroscopy (SEM-EDS). SEM microphotograph reveals that rock is dominated by brightly illuminated quartz imbedded in the matrix with mica and other minor minerals. The X-ray mineral composition data have been plotted with SEM-EDS mineral composition, data shows that the composition obtained by two technique are in consistent within the experimental limit and in good agreement. Further plot of chemical composition of constituent oxides of granite sample by XRD and SEM-EDS confirm the consistency of two technique and similarity with Jharkhand mean granite composition. Silica composition have been plotted with trace element Pb, Ba, Zr, Rb, and Alumina composition with Pb , Ba, Zr and Rb shows that these elements are randomly imbedded in the matrix with almost uniform composition. Al2O 3 composition have been plotted wit...