Shamindra Sengupta - Academia.edu (original) (raw)

Papers by Shamindra Sengupta

Journal of Oral Sign, 2013

Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by... more Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian subcontinent and areca nut chewing has been strongly associated with the onset and progression of the disease. Various other etiologic factors like genetic, immunologic, nutritional, autoimmune have been also implicated in the pathogenesis of the disease. With the easily availability and effective economic pricing of commercial available areca nut the frequency of the disease has increased by many folds in the developing nations. Various treatment modalities are now available but the cessation of the habit should be prime importance during the treatment planning. The treatment of patient of OSMF depends on the degree of involvement. The aim of this paper is to discuss about the various factors involved in the etiopathogenesis of the disease along with the medical management for the patients of OSMF. Furthermore, since the aetiology is mostly linked to a habit, healthcare professionals have a very important role to play in terms of lifestyle modification advice, which may significantly decrease the disease incidence, progression and morbidity, if not mortality.

Journal of Orofacial & Health Sciences, 2013

Oral submucous fibrosis (OSMF), a precancerous condition of the oral cavity, characterized by pro... more Oral submucous fibrosis (OSMF), a precancerous condition of the oral cavity, characterized by progressive and excessive accumulation of extracellular matrix collagen. The condition is characterized by mucosal rigidity of varied intensity caused by fibrosis of the superficial connective tissue and leading to secondary atrophic or hypoplastic changes in the epithelium. It has been discovered that exposure of buccal mucosal fibroblasts to alkaloids may cause aggregation of collagen. The present study was undertaken to know the effect of H&E, Van Gieson and Masson trichome stain on the collagen fibers of OSMF. The staining reactions of the above three stains will be evaluated to know which stains collagen fibers best in light microscopy. Histological confirmed cases of OSMF would be selected from the archives of department of oral pathology of our college from last five years and will be analyzed. Three sections will be prepared for each case and will be stained by H&E, van Gieson and M...

ABSTRACT Psoriasis is a common skin disorder characterized by focal formation of raised plaques t... more ABSTRACT Psoriasis is a common skin disorder characterized by focal formation of raised plaques that constantly shed scales derived from excessive growth of skin epithelial cells. The disease is characterized by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils, and other types of leukocyte in the affected skin. Psoriasis is now considered as a T cell-mediated inflammation of the skin. Types of psoriasis that may be clinically encountered include plaque psoriasis, guttate psoriasis, erythrodermic psoriasis, pustular psoriasis, nail psoriasis, psoriatic arthritis, and scalp psoriasis. Psoriasis is believed to be genetically linked but can also be triggered by mechanical, ultraviolet, and chemical injury; various infections; prescription drug use; psychological stress; smoking; and other factors.

1 Professor, Department of Oral Pathology and Microbiology, D.J.College of Dental Sciences and Re... more 1 Professor, Department of Oral Pathology and Microbiology, D.J.College of Dental Sciences and Research, Ajit Mahal, Niwari Road, Modinagar 201204, Ghaziabad, Uttar Pradesh, India. 2 Senior Lecturer, Department of Oral Pathology and Microbiology, 4 Reader, Department of Prosthodontics, Genesis Institute of Dental Sciences and Research, Ferozepur, India. 3 Reader, Department of Oral Pathology and Microbiology, ITS Dental College, Greater Noida, India.

Nigerian Journal of Clinical Practice, 2011

Odontogenic keratocyst, which is developmental in nature, is an intraosseous lesion though on rar... more Odontogenic keratocyst, which is developmental in nature, is an intraosseous lesion though on rare occasions it may occur in an extraosseous location. The extraosseous variant is referred to as peripheral odontogenic keratocyst. Though, clinically, peripheral odontogenic keratocyst resembles the gingival cyst of adults, it has histologic features that are pathognomonic of odontogenic keratocyst. This article presents a case of this uncommon entity.

Journal of Forensic Dental Sciences, 2014

Aim: The aim of this study was to evaluate the awareness of practicing dentists about the subject... more Aim: The aim of this study was to evaluate the awareness of practicing dentists about the subject of forensic odontology and to assess their willingness to maintain and share patient records. Materials and Methods: A blind questionnaire survey was carried out among 100 randomly selected practicing dentists in district Ghaziabad, Uttar Pradesh. Results: Most of the dentists interviewed were familiar with the subject of forensic odontology and its relation to dentistry, despite forensic dentistry having been newly introduced since 2007 into the undergraduate dental curriculum in India. However, dental records are maintained by only a few dentists, and only a very small percentage of them reported to have shared records, which may have helped in the identification of victims in a mass disaster. Conclusion: The result of our survey concluded that more awareness needs to be developed among practicing dentists regarding maintaining and sharing patient records for forensic odontology to succeed as a victim identification tool.

Journal of Maxillofacial and Oral Surgery, 2013

Your article is protected by copyright and all rights are held exclusively by Association of Oral... more Your article is protected by copyright and all rights are held exclusively by Association of Oral and Maxillofacial Surgeons of India. This e-offprint is for personal use only and shall not be self-archived in electronic repositories. If you wish to self-archive your work, please use the accepted author's version for posting to your own website or your institution's repository. You may further deposit the accepted author's version on a funder's repository at a funder's request, provided it is not made publicly available until 12 months after publication.

Forensic Odontology has been defined by the Federation Dentaire Internationale (FDI) as that “ br... more Forensic Odontology has been defined by the Federation Dentaire Internationale (FDI) as that “ branch of dentistry which, in the interest of justice, deals with proper handling and examination of dental evidence, and with the proper evaluation and presentation of dental findings”. Different evidences used for identification of victims and culprits are teeth, jaw bone, saliva, radiographs, bite marks, palatal rugae, dental records, dental casts, DNA, blood, lip prints, denture and microscopic slides. As evidence is the backbone of all investigations, strict procedure and techniques must accompany the collection and preservation of evidence. The central goal is to maintain evidence in a state as close to that it was in when the incidence in question occurred. Since the evidence can come in so many different forms, the packaging and storage of evidence must be equally diverse. Failure to follow proper procedure and techniques in collecting and storing evidence can significantly impact ...

Journal of Oral Sign, 2013

Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by... more Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian subcontinent and areca nut chewing has been strongly associated with the onset and progression of the disease. Various other etiologic factors like genetic, immunologic, nutritional, autoimmune have been also implicated in the pathogenesis of the disease. With the easily availability and effective economic pricing of commercial available areca nut the frequency of the disease has increased by many folds in the developing nations. Various treatment modalities are now available but the cessation of the habit should be prime importance during the treatment planning. The treatment of patient of OSMF depends on the degree of involvement. The aim of this paper is to discuss about the various factors involved in the etiopathogenesis of the dis...

Psoriasis is a common skin disorder characterized by focal formation of raised plaques that const... more Psoriasis is a common skin disorder characterized by focal formation of raised plaques that constantly shed scales derived from excessive growth of skin epithelial cells. The disease is characterized by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils, and other types of leukocyte in the affected skin. Psoriasis is now considered as a T cell-mediated inflammation of the skin. Types of psoriasis that may be clinically encountered include plaque psoriasis, guttate psoriasis, erythrodermic psoriasis, pustular psoriasis, nail psoriasis, psoriatic arthritis, and scalp psoriasis. Psoriasis is believed to be genetically linked but can also be triggered by mechanical, ultraviolet, and chemical injury; various infections; prescription drug use; psychological stress; smoking; and other factors.

Journal of Cranio Maxillary Diseases, Jul 1, 2013

The Langerhans cells (LC) are the bone marrow-derived dendritic, antigen-presenting cells of the ... more The Langerhans cells (LC) are the bone marrow-derived dendritic, antigen-presenting cells of the skin and oral mucosa. These are characterized by a unique intra cytoplasmic organelle - the Birbeck granule and constitutively expresses class II major histocompatibility complex (MHC) molecules and the Cluster differentiation Ia (CD1a) glycoprotein. The LC represents one of the most potent APC of the body and fulfills an important role in detecting foreign antigen entering the body through the skin and in immune surveillance. The distribution of LC is restricted to the skin, lymph nodes, bronchial mucosa, and thymus. This paper reviews the classification, origin, and the role of the LC in various pathological conditions.

... Oral Submucous Fibrosis: Review on Etiopathogenesis Sunita N Dyavanagoudar* Department of Ora... more ... Oral Submucous Fibrosis: Review on Etiopathogenesis Sunita N Dyavanagoudar* Department of Oral Pathology, Sri Hassanamba Dental College and Hospital, Vidyanagar, Hassan, Karnataka, India Journal of Cancer Science & Therapy - Open Access ...

Journal of Oral and Maxillofacial Pathology, 2013

The study evaluated pathognomic histopathological features with the help of light microscopy for ... more The study evaluated pathognomic histopathological features with the help of light microscopy for detecting the integration of human papillomavirus (HPV) (type 16 and 18) in oral squamous cell carcinoma (OSCC). Materials and Methods: Forty-five histopathologically diagnosed cases of OSCC were evaluated for the presence of E6/E7 protein of HPV (16 + 18) with the help of nested multiplex polymerase chain reaction. Both HPV-positive and-negative cases were evaluated for four histological features: Koilocytes, dyskeratosis, invasion, and alteration of collagen. Results: Fischer's exact test showed significant difference (P < 0.01%) for the presence of koilocytes and dyskeratosis, whereas no difference was observed for invasion and alteration in collagen between HPV-positive and-negative OSCC. Conclusion: The presence of koilocytes and dyskeratosis at light microscopic level can be used as a marker for the presence of HPV (type 16 and 18) in OSCC.

European Journal of General Dentistry, 2013

Clinical Cancer Investigation Journal, Apr 1, 2013

Genetic predisposition The relative risk for the development of HL increases approximately 100-fo... more Genetic predisposition The relative risk for the development of HL increases approximately 100-fold in monozygous twins and 7-fold in siblings of patients less than 45 years of age. Human Update on Hodgkin's lymphoma leukocyte antigen (HLA) associations have been described in familial HL including HLA A1, B5, B18, DPB1, DRB1, DQA1, and DQB1. [3] Epstein-Barr virus and classical Hodgkin's lymphoma A total of 20-100% of HL appears to be associated with Epstein-Barr virus (EBV) infection, the association varying with age (more frequent in children and older adults), gender (more frequent in males), geography (higher in Asia than in the US), and histology. [3] Sjogren syndrome and Hodgkin's lymphoma Sjogren syndrome (SS) is commonly associated with non-HLs but rarely with HLs. [4] SS is an autoimmune disease characterized by a lymphocytic infi ltration of salivary and lacrimal glands leading to a progressive destruction of these glands and by production of autoantibodies. This disorder is either isolated (primary SS) or associated with other systemic diseases (secondary SS). SS is characterized histologically by mononuclear cellular infi ltration of the salivary and lacrimal glands and serologically by the presence of many tissue component antibodies. The most serious complication of SS is the appearance of parotid gland lymphomas. The warning signs are the presence of persistent parotid gland swelling, regional or generalized lymphadenopathies, hepatosplenomegaly,

Journal of Oral and Maxillofacial Pathology, 2010

Primary intraosseous carcinoma arising as a de novo lesion is a unique and rare carcinoma affecti... more Primary intraosseous carcinoma arising as a de novo lesion is a unique and rare carcinoma affecting the jaws, especially at younger ages. Two case reports, a 26-year-old Indian female with primary intraosseous squamous cell carcinoma and a 16-year-old Indian male with intraosseous carcinoma arising in an odontogenic cyst, both within the body of the mandible, are presented here.

Benin Journal of Postgraduate Medicine, 2009

Journal of Oral Sign, 2013

Journal of oral and maxillofacial pathology : JOMFP

The aim of this study was to analyze and compare the effects of tobacco on salivary pH between to... more The aim of this study was to analyze and compare the effects of tobacco on salivary pH between tobacco chewers, smokers and controls. A total of 60 subjects (males and females) aged 25-40 years, were divided equally into three groups: Tobacco smokers (Group A), chewers (Group B) and controls (Group C). Saliva of each subject was collected under resting condition. Salivary pH was determined using the specific salivary pH meter. The mean (±standard deviation) pH for Group A was 6.75 (±0.11), Group B was 6.5 (±0.29) and Group C was 7.00 (±0.28) after comparison. The significant results showed lower salivary pH in Groups A and B as compared to controls. Salivary pH was lowest in Group B compared to Group A and Group C. This study indicates that a lower (acidic) salivary pH was observed in tobacco users as compared with control. These alterations in pH due to the long-term effect of tobacco use can render oral mucosa vulnerable to various oral and dental diseases.

Primary Intraosseous Carcinoma (PIOC) is regarded as a rare malignant neoplasm of the jaws which ... more Primary Intraosseous Carcinoma (PIOC) is regarded as a rare malignant neoplasm of the jaws which shows locally aggressive behavior with poor prognosis. Through knowledge of the various features of PIOC such as clinical, radiographic and histopathologic, not only allows for accurate and early diagnosis of the lesion but also helps in an early and appropriate treatment with better prognosis. This article reports a case presenting with typical features of PIOC due to suspected use of cold cure acrylic resin which was allowed to polymerize inside the oral cavity in contact with soft and hard tissues. Lack of awareness about the cytotoxic and genotoxic potential of MMA needs to be highlighted so that intra-oral curing of MMA should be avoided.

Journal of Oral Sign, 2013

Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by... more Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian subcontinent and areca nut chewing has been strongly associated with the onset and progression of the disease. Various other etiologic factors like genetic, immunologic, nutritional, autoimmune have been also implicated in the pathogenesis of the disease. With the easily availability and effective economic pricing of commercial available areca nut the frequency of the disease has increased by many folds in the developing nations. Various treatment modalities are now available but the cessation of the habit should be prime importance during the treatment planning. The treatment of patient of OSMF depends on the degree of involvement. The aim of this paper is to discuss about the various factors involved in the etiopathogenesis of the disease along with the medical management for the patients of OSMF. Furthermore, since the aetiology is mostly linked to a habit, healthcare professionals have a very important role to play in terms of lifestyle modification advice, which may significantly decrease the disease incidence, progression and morbidity, if not mortality.

Journal of Orofacial & Health Sciences, 2013

Oral submucous fibrosis (OSMF), a precancerous condition of the oral cavity, characterized by pro... more Oral submucous fibrosis (OSMF), a precancerous condition of the oral cavity, characterized by progressive and excessive accumulation of extracellular matrix collagen. The condition is characterized by mucosal rigidity of varied intensity caused by fibrosis of the superficial connective tissue and leading to secondary atrophic or hypoplastic changes in the epithelium. It has been discovered that exposure of buccal mucosal fibroblasts to alkaloids may cause aggregation of collagen. The present study was undertaken to know the effect of H&E, Van Gieson and Masson trichome stain on the collagen fibers of OSMF. The staining reactions of the above three stains will be evaluated to know which stains collagen fibers best in light microscopy. Histological confirmed cases of OSMF would be selected from the archives of department of oral pathology of our college from last five years and will be analyzed. Three sections will be prepared for each case and will be stained by H&E, van Gieson and M...

ABSTRACT Psoriasis is a common skin disorder characterized by focal formation of raised plaques t... more ABSTRACT Psoriasis is a common skin disorder characterized by focal formation of raised plaques that constantly shed scales derived from excessive growth of skin epithelial cells. The disease is characterized by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils, and other types of leukocyte in the affected skin. Psoriasis is now considered as a T cell-mediated inflammation of the skin. Types of psoriasis that may be clinically encountered include plaque psoriasis, guttate psoriasis, erythrodermic psoriasis, pustular psoriasis, nail psoriasis, psoriatic arthritis, and scalp psoriasis. Psoriasis is believed to be genetically linked but can also be triggered by mechanical, ultraviolet, and chemical injury; various infections; prescription drug use; psychological stress; smoking; and other factors.

1 Professor, Department of Oral Pathology and Microbiology, D.J.College of Dental Sciences and Re... more 1 Professor, Department of Oral Pathology and Microbiology, D.J.College of Dental Sciences and Research, Ajit Mahal, Niwari Road, Modinagar 201204, Ghaziabad, Uttar Pradesh, India. 2 Senior Lecturer, Department of Oral Pathology and Microbiology, 4 Reader, Department of Prosthodontics, Genesis Institute of Dental Sciences and Research, Ferozepur, India. 3 Reader, Department of Oral Pathology and Microbiology, ITS Dental College, Greater Noida, India.

Nigerian Journal of Clinical Practice, 2011

Odontogenic keratocyst, which is developmental in nature, is an intraosseous lesion though on rar... more Odontogenic keratocyst, which is developmental in nature, is an intraosseous lesion though on rare occasions it may occur in an extraosseous location. The extraosseous variant is referred to as peripheral odontogenic keratocyst. Though, clinically, peripheral odontogenic keratocyst resembles the gingival cyst of adults, it has histologic features that are pathognomonic of odontogenic keratocyst. This article presents a case of this uncommon entity.

Journal of Forensic Dental Sciences, 2014

Aim: The aim of this study was to evaluate the awareness of practicing dentists about the subject... more Aim: The aim of this study was to evaluate the awareness of practicing dentists about the subject of forensic odontology and to assess their willingness to maintain and share patient records. Materials and Methods: A blind questionnaire survey was carried out among 100 randomly selected practicing dentists in district Ghaziabad, Uttar Pradesh. Results: Most of the dentists interviewed were familiar with the subject of forensic odontology and its relation to dentistry, despite forensic dentistry having been newly introduced since 2007 into the undergraduate dental curriculum in India. However, dental records are maintained by only a few dentists, and only a very small percentage of them reported to have shared records, which may have helped in the identification of victims in a mass disaster. Conclusion: The result of our survey concluded that more awareness needs to be developed among practicing dentists regarding maintaining and sharing patient records for forensic odontology to succeed as a victim identification tool.

Journal of Maxillofacial and Oral Surgery, 2013

Your article is protected by copyright and all rights are held exclusively by Association of Oral... more Your article is protected by copyright and all rights are held exclusively by Association of Oral and Maxillofacial Surgeons of India. This e-offprint is for personal use only and shall not be self-archived in electronic repositories. If you wish to self-archive your work, please use the accepted author's version for posting to your own website or your institution's repository. You may further deposit the accepted author's version on a funder's repository at a funder's request, provided it is not made publicly available until 12 months after publication.

Forensic Odontology has been defined by the Federation Dentaire Internationale (FDI) as that “ br... more Forensic Odontology has been defined by the Federation Dentaire Internationale (FDI) as that “ branch of dentistry which, in the interest of justice, deals with proper handling and examination of dental evidence, and with the proper evaluation and presentation of dental findings”. Different evidences used for identification of victims and culprits are teeth, jaw bone, saliva, radiographs, bite marks, palatal rugae, dental records, dental casts, DNA, blood, lip prints, denture and microscopic slides. As evidence is the backbone of all investigations, strict procedure and techniques must accompany the collection and preservation of evidence. The central goal is to maintain evidence in a state as close to that it was in when the incidence in question occurred. Since the evidence can come in so many different forms, the packaging and storage of evidence must be equally diverse. Failure to follow proper procedure and techniques in collecting and storing evidence can significantly impact ...

Journal of Oral Sign, 2013

Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by... more Oral submucous fibrosis (OSMF) is a chronic incidious disease of the oral mucosa characterized by inflammation and a progressive fibrosis of the lamina propria and deeper connective tissues. It is a condition predominantly seen among people of Indian subcontinent and areca nut chewing has been strongly associated with the onset and progression of the disease. Various other etiologic factors like genetic, immunologic, nutritional, autoimmune have been also implicated in the pathogenesis of the disease. With the easily availability and effective economic pricing of commercial available areca nut the frequency of the disease has increased by many folds in the developing nations. Various treatment modalities are now available but the cessation of the habit should be prime importance during the treatment planning. The treatment of patient of OSMF depends on the degree of involvement. The aim of this paper is to discuss about the various factors involved in the etiopathogenesis of the dis...

Psoriasis is a common skin disorder characterized by focal formation of raised plaques that const... more Psoriasis is a common skin disorder characterized by focal formation of raised plaques that constantly shed scales derived from excessive growth of skin epithelial cells. The disease is characterized by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils, and other types of leukocyte in the affected skin. Psoriasis is now considered as a T cell-mediated inflammation of the skin. Types of psoriasis that may be clinically encountered include plaque psoriasis, guttate psoriasis, erythrodermic psoriasis, pustular psoriasis, nail psoriasis, psoriatic arthritis, and scalp psoriasis. Psoriasis is believed to be genetically linked but can also be triggered by mechanical, ultraviolet, and chemical injury; various infections; prescription drug use; psychological stress; smoking; and other factors.

Journal of Cranio Maxillary Diseases, Jul 1, 2013

The Langerhans cells (LC) are the bone marrow-derived dendritic, antigen-presenting cells of the ... more The Langerhans cells (LC) are the bone marrow-derived dendritic, antigen-presenting cells of the skin and oral mucosa. These are characterized by a unique intra cytoplasmic organelle - the Birbeck granule and constitutively expresses class II major histocompatibility complex (MHC) molecules and the Cluster differentiation Ia (CD1a) glycoprotein. The LC represents one of the most potent APC of the body and fulfills an important role in detecting foreign antigen entering the body through the skin and in immune surveillance. The distribution of LC is restricted to the skin, lymph nodes, bronchial mucosa, and thymus. This paper reviews the classification, origin, and the role of the LC in various pathological conditions.

... Oral Submucous Fibrosis: Review on Etiopathogenesis Sunita N Dyavanagoudar* Department of Ora... more ... Oral Submucous Fibrosis: Review on Etiopathogenesis Sunita N Dyavanagoudar* Department of Oral Pathology, Sri Hassanamba Dental College and Hospital, Vidyanagar, Hassan, Karnataka, India Journal of Cancer Science & Therapy - Open Access ...

Journal of Oral and Maxillofacial Pathology, 2013

The study evaluated pathognomic histopathological features with the help of light microscopy for ... more The study evaluated pathognomic histopathological features with the help of light microscopy for detecting the integration of human papillomavirus (HPV) (type 16 and 18) in oral squamous cell carcinoma (OSCC). Materials and Methods: Forty-five histopathologically diagnosed cases of OSCC were evaluated for the presence of E6/E7 protein of HPV (16 + 18) with the help of nested multiplex polymerase chain reaction. Both HPV-positive and-negative cases were evaluated for four histological features: Koilocytes, dyskeratosis, invasion, and alteration of collagen. Results: Fischer's exact test showed significant difference (P < 0.01%) for the presence of koilocytes and dyskeratosis, whereas no difference was observed for invasion and alteration in collagen between HPV-positive and-negative OSCC. Conclusion: The presence of koilocytes and dyskeratosis at light microscopic level can be used as a marker for the presence of HPV (type 16 and 18) in OSCC.

European Journal of General Dentistry, 2013

Clinical Cancer Investigation Journal, Apr 1, 2013

Genetic predisposition The relative risk for the development of HL increases approximately 100-fo... more Genetic predisposition The relative risk for the development of HL increases approximately 100-fold in monozygous twins and 7-fold in siblings of patients less than 45 years of age. Human Update on Hodgkin's lymphoma leukocyte antigen (HLA) associations have been described in familial HL including HLA A1, B5, B18, DPB1, DRB1, DQA1, and DQB1. [3] Epstein-Barr virus and classical Hodgkin's lymphoma A total of 20-100% of HL appears to be associated with Epstein-Barr virus (EBV) infection, the association varying with age (more frequent in children and older adults), gender (more frequent in males), geography (higher in Asia than in the US), and histology. [3] Sjogren syndrome and Hodgkin's lymphoma Sjogren syndrome (SS) is commonly associated with non-HLs but rarely with HLs. [4] SS is an autoimmune disease characterized by a lymphocytic infi ltration of salivary and lacrimal glands leading to a progressive destruction of these glands and by production of autoantibodies. This disorder is either isolated (primary SS) or associated with other systemic diseases (secondary SS). SS is characterized histologically by mononuclear cellular infi ltration of the salivary and lacrimal glands and serologically by the presence of many tissue component antibodies. The most serious complication of SS is the appearance of parotid gland lymphomas. The warning signs are the presence of persistent parotid gland swelling, regional or generalized lymphadenopathies, hepatosplenomegaly,

Journal of Oral and Maxillofacial Pathology, 2010

Primary intraosseous carcinoma arising as a de novo lesion is a unique and rare carcinoma affecti... more Primary intraosseous carcinoma arising as a de novo lesion is a unique and rare carcinoma affecting the jaws, especially at younger ages. Two case reports, a 26-year-old Indian female with primary intraosseous squamous cell carcinoma and a 16-year-old Indian male with intraosseous carcinoma arising in an odontogenic cyst, both within the body of the mandible, are presented here.

Benin Journal of Postgraduate Medicine, 2009

Journal of Oral Sign, 2013

Journal of oral and maxillofacial pathology : JOMFP

The aim of this study was to analyze and compare the effects of tobacco on salivary pH between to... more The aim of this study was to analyze and compare the effects of tobacco on salivary pH between tobacco chewers, smokers and controls. A total of 60 subjects (males and females) aged 25-40 years, were divided equally into three groups: Tobacco smokers (Group A), chewers (Group B) and controls (Group C). Saliva of each subject was collected under resting condition. Salivary pH was determined using the specific salivary pH meter. The mean (±standard deviation) pH for Group A was 6.75 (±0.11), Group B was 6.5 (±0.29) and Group C was 7.00 (±0.28) after comparison. The significant results showed lower salivary pH in Groups A and B as compared to controls. Salivary pH was lowest in Group B compared to Group A and Group C. This study indicates that a lower (acidic) salivary pH was observed in tobacco users as compared with control. These alterations in pH due to the long-term effect of tobacco use can render oral mucosa vulnerable to various oral and dental diseases.

Primary Intraosseous Carcinoma (PIOC) is regarded as a rare malignant neoplasm of the jaws which ... more Primary Intraosseous Carcinoma (PIOC) is regarded as a rare malignant neoplasm of the jaws which shows locally aggressive behavior with poor prognosis. Through knowledge of the various features of PIOC such as clinical, radiographic and histopathologic, not only allows for accurate and early diagnosis of the lesion but also helps in an early and appropriate treatment with better prognosis. This article reports a case presenting with typical features of PIOC due to suspected use of cold cure acrylic resin which was allowed to polymerize inside the oral cavity in contact with soft and hard tissues. Lack of awareness about the cytotoxic and genotoxic potential of MMA needs to be highlighted so that intra-oral curing of MMA should be avoided.