Shyam Sivasamy - Academia.edu (original) (raw)

Papers by Shyam Sivasamy

World Journal Of Advanced Research and Reviews, Jun 30, 2024

Journal of Indian Society of Pedodontics and Preventive Dentistry, Dec 31, 2022

Environmental Pollution, Jan 31, 2024

Journal of basic and clinical pharmacy, 2015

Environmental epidemiology, Oct 1, 2019

Journal of Oral Pathology & Medicine, Feb 22, 2022

IntroductionThis scoping review was done to study the immunohistochemical biomarkers involved in ... more IntroductionThis scoping review was done to study the immunohistochemical biomarkers involved in the pathogenesis and malignant transformation of oral submucous fibrosis (OSF), in literature published from 2010 to 2021.MethodThe protocol was adapted from the Joanna Briggs Institute Reviewer's Manual (2017), and reported according to the PRISMA guidelines for Scoping Reviews.ResultsEighty‐six studies included in this review reported 84 immunohistochemical (IHC) biomarkers in OSF: 10 epithelial markers, 28 connective tissue markers, 22 proliferative markers, and 24 other biomarkers that are transcription factors, cancer stem cell markers, cell signaling markers, proteins, and enzymes. The commonly reported IHC biomarkers were alpha‐smooth muscle actin (α‐SMA) and E‐cadherin (seven articles each) followed by vascular endothelial growth factor (VEGF) and CD34 (six articles each), p53, p63, and Ki67 (five articles each). α‐SMA, Ki67, CD105, and hTERT were significantly increased in oral squamous cell carcinoma arising in a background of OSF (OSCC‐OSF) compared with OSF and normal subjects.ConclusionThe identified surrogate IHC biomarkers reported in OSF in this scoping review require validation with long‐term prospective studies to facilitate early diagnosis, for use in risk assessment, and plan appropriate treatment for OSF in clinical practice.Open Science Framework ID: osf.io/epwra

International Journal of Research Publication and Reviews

$Research paper thumbnail of A Brief Review on Children\'s Oral Health Related Quality of Life Measures in Dentistry$

Journal of Scientific Dentistry

International Journal of Social Rehabilitation

Substance abuse is a serious public health problem across the world and is one of the biggest cur... more Substance abuse is a serious public health problem across the world and is one of the biggest curses that modernsociety is facing. The assessment of nicotine addiction has been considered as a key topic as research into tobaccoaddiction progresses. Improved measurement may be required to make progress in tobacco research. The way nicotineaddiction is defined and assessed can have an impact on the findings and interpretations of studies and clinical trials.The Fagerström Tolerance Questionnaire (FTQ) and its shorter counterpart, the Fagerström Test for NicotineDependence (FTND), are the most well-known measures in terms of history and have been utilised in clinical andresearch contexts. The Fagerström scales, on the other hand, were designed to assess physical tolerance and thus donot assess several important aspects of nicotine dependence, such as cravings, subjective compulsion to smoke,nicotine withdrawal, behavioural saliency, or behavioural automaticity, which are frequently reg...

Journal of Indian Society of Pedodontics and Preventive Dentistry, Apr 21, 2022

Purpose: The study was planned to develop and validate a novel middle childhood oral health impac... more Purpose: The study was planned to develop and validate a novel middle childhood oral health impact scale (MCOHIS) for 6- to 9-year-old children in India. Methodology: A cross-sectional study design was employed to develop and validate MCOHIS in the sequential phases. A panel of ten pediatric dentists evaluated a pool of 36 items corresponding to the oral health-related quality of life (OHRQoL) of children. MCOHIS with 20 items under five domains was formulated and content validation was done. Cohen's kappa statistics was employed to measure the concordance between the child's self-report and the caregiver's proxy report. Concurrent validation was done among 130 participants from 13 districts of Tamil Nadu state, India. Discriminant validity was checked among another sample of 60 participants. Internal consistency and test-retest reliability of MCOHIS were assessed using Cronbach's alpha and Kappa statistics respectively. Results: MCOHIS had adequate content validation with Scale Level Content Validity Index / Average score of 0.94 for relevance. There was a statistically significant inter-rater reliability observed between the child's self-report and caregivers' proxy report in all items with a moderate to substantial agreement. Concurrent validation showed a statistically significant positive correlation with a Rho value of 0.712. There was a statistically significant difference noted in overall discriminant validity (P < 0.001). Acceptable internal consistency reliability was observed with Cronbach's alpha value of 0.75. Test-retest reliability showed a high stability coefficient of 0.98. Conclusions: MCOHIS was found to be a valid and reliable age-specific tool for assessing the OHRQoL of Indian children aged 6–9 years.

Journal of Indian Association of Public Health Dentistry, Jul 1, 2012

European Journal of Dental Education, 2021

Dental profession is one of the most stressful healthcare occupations. Paediatric dental postgrad... more Dental profession is one of the most stressful healthcare occupations. Paediatric dental postgraduates face multifaceted challenges in their everyday practice. This study aimed to determine the sources of stress amongst paediatric dental postgraduate students in India using a mixed-method approach. A sequential mixed-methods approach was employed. In the quantitative phase, a cross-sectional web-based questionnaire survey was conducted amongst paediatric dental postgraduates in India using the "Google Forms application" link. Based on the Dental Environment Stress (DES) questionnaire, the stress PACT questionnaire which includes 35 items was framed and validated. This validated questionnaire was used in the survey. In the qualitative phase, one-on-one, semi-structured telephone interviews were conducted amongst 12 postgraduates. A total of 422 participants took part in the quantitative survey. Academic and specialty-related domains were found to be the significant causes of stress amongst the five domains (p < .001). The top three stressful factors were as follows: getting an ideal case for clinical exams (68.2%), financial resources for conferences, dissertation, short studies and publications (53.2%) and fear of unemployment after graduation (52.3%). Based on qualitative interviews, four themes were derived, namely choice of paediatric dentistry, postgraduate life experience, stress management and expected changes in postgraduate life. Psychological well-being of the student is an important factor that influences the overall performance of students. Identifying the stress factors and using appropriate coping strategies can help postgraduates achieve personal, academic and professional success.

Medico-Legal Update, 2020

Background: Mobile health (mhealth) intervention has been proved to be effective in weight loss, ... more Background: Mobile health (mhealth) intervention has been proved to be effective in weight loss, diabetes control and tobacco cessation Objective: To assess the effectiveness of mhealth intervention to reduce consumption of cariogenic diet. Design and setting: Randomized controlled trial in field setting Materials and method: Forty two adolescents who were in the "Watch-out" zone of sweet score were recruited for the study. The subjects were randomly allotted into the test group (n=21) and the control group (n=21). A three day diet diary was recorded from all study subjects and the average sweet score was assessed at baseline and at post intervention. The subjects in the control group received standard one to one dietary instructions tailored to the needs of the subjects only once at the start of the study. Subjects in the test group received tailored dietary instructions once daily through mobile application (Whatsapp). Intra-group comparison was made using Wilcoxon signed rank test and inter-group comparison was made using Mann Whitney U test. P value <0.05 was considered statistically significant. Results: The sweet score for the control group at baseline was 20.9±6.06 while the post test score was 13.16±4.37 and the difference was statistically significant (p=0.002). The sweet score for the test group at baseline was 18.02±4.03 while the post test score was 14.5±7.74 and the difference was statistically significant (p=0.03). However, there was no statistically significant difference in sweet score between the two groups at the end of the trail. Conclusion: mhealth intervention is effective in reducing sweet score among adolescents.

Tobacco Induced Diseases, 2021

Articles reporting research may be full length or brief reports. These should report original res... more Articles reporting research may be full length or brief reports. These should report original research findings within the journal's scope. Papers should generally be a maximum of 4000 words in length, excluding tables, references, abstract and key points of the article, whilst references should not exceed 36. Review Papers Comprehensive, authoritative, reviews within the journal's scope. Review articles provide a review of the literature. There are two types of review papers:-systematic review papers: respond to a specific research question, accrue from criterion-based selection of sources, include a quantitative synthesis that includes a statistical method (meta-analysis) and should adhere to PRISMA guidelines. Guidelines used for abstracting data and assessing data quality and validity should be noted in methods section.-narrative reviews: the research question may be broad, and the scope of this review is to discuss a specific topic and keep the readers up-to-date about it. This type of review does not necessarily include a methodological approach and its synthesis is usually qualitative. Narrative reviews should include a "developments" section, with details regarding data sources used, keywords applied, time restrictions and study types selected. All review papers should be generally less than 6000 words, excluding abstract, tables, figures and references. References should not exceed 50 unless on a topic that has an extensive evidence base. The conclusion of the reviews must be specific and stem from the findings. Short Reports Brief reports of data from original research. Short reports are shorter versions of original articles, may include one table or figure, should not exceed 1500 words and 15 references. Short reports are suitable for the presentation of research that extends previously published research, including the reporting of additional evidence and confirmatory results in other settings, as well as negative results. Authors must clearly acknowledge any work upon which they are building, both published and unpublished. Study Protocols Articles describing a research protocol of a study. This article type can be for proposed or for ongoing research and should contain the background, research hypothesis, rationale a detailed methodology of the study. The SPIRIT 2013 Checklist guidelines ideally should be applied. Study protocols submitted for publication must have received ethics approval. Protocols of randomized trials should follow the CONSORT guidelines and must have a trial registration number, while observational studies should follow STROBE guidelines. Methodology Papers Papers that present different methodological approaches that can be used to investigate problems in a relevant scientific field and to encourage innovation. It is suggested that case studies or practical examples, which can be existing ones, are included to demonstrate the consistency and applicability of the methodology. Methodology papers should be generally less than 6000 words, excluding abstract, tables, figures and references. References should not exceed 50. Letters to the Editor A letter to the Editor is a brief report that is within the journal's scope and of particular interest to the community, but not suitable as a standard research article or as a short report. Letters to the editor may also report original research data, if the sample size is small. A maximum of ten articles may be included in the references. Letters intended for publication should be a maximum of 500 words, contain 10 references, and up to one table or figure. These rules apply both for research letters, and letters that respond to articles published in the journal. Letters to the editor are subject to editorial editing so as to streamline with the journal's style. Editorials Editorials are written by members of the Editorial Board or by invited topic experts and may reflect current articles within TID

Journal of Education and Ethics in Dentistry, 2016

Background: With the advent of Consumer Protection Act in 1986, awareness among the public on the... more Background: With the advent of Consumer Protection Act in 1986, awareness among the public on their consumer rights has increased. Health professionals can be litigated for medical negligence under the Consumer Protection Act. This had led to an increase in medicolegal issues in the recent past. The advocates (Doctors of Law) play a vital role in solving these issues and delivering justice to the victims. Hence, a sound knowledge on medical and dental jurisprudence is mandatory for these legal professionals. Aim: The aim of this study is to assess the knowledge, attitude, and practice regarding dental jurisprudence among the advocates practising in Chennai, India. Materials and Methods: A cross-sectional study was conducted among 180 advocates belonging to three groups each with sixty advocates namely: Group I (advocates completed under graduation in law), Group II (advocates specialized in Criminology), and Group III (advocates specialized in other fields of law). A 26 item questio...

Objective – To assess the oral health status and treatment needs of 5 and 12 year old rural schoo... more Objective – To assess the oral health status and treatment needs of 5 and 12 year old rural school children with poor access to oral health care services. Materials and Methods – A cross sectional survey was conducted among 5 and 12 year old children in Kaveripakkam block of Vellore district (n=184). The oral health status was recorded using WHO proforma 1997. Results – The prevalence of dental caries was 68.5% among 5 year old children and 30.5% among 12 year old children. Gingival bleeding on probing was observed among 13.76% and 30.0% of 5 year and 12 year old children respectively, whereas calculus was observed among 2.73% and 18.75% respectively. About 7.5% of 12 year old children had either questionable or mild fluorosis. The greatest need of treatment among this population was one surface restoration in 64.3% and 61.3% of 5 year and 12 year old children respectively, followed by two surface restorations, pulpal restorations and extractions. Conclusion – Unmet treatment need w...

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2021

Objective: The objective of the study is to determine the association between nonsyndromic oral c... more Objective: The objective of the study is to determine the association between nonsyndromic oral clefts (OC) in children and ABO, Rh blood groups, lip, and dermatoglyphic patterns of their unaffected parents. Methods: This case–control study was conducted at a tertiary cleft center in Chennai, India, among 240 individuals comprising 80 units (40 cases and controls, respectively). Each unit (triad) was constituted by a child (0–12 years of age) either born with nonsyndromic OC (cases) or with no diagnosed congenital anomaly (control) and their unaffected parents (mother and father). ABO and Rh blood groups, specific lip print, fingerprint pattern, and palmar asymmetry were recorded for each individual. Strength of association of related factors was assessed by multivariable logistic regression reported as adjusted odds ratios and 95% confidence interval. Results: A1-positive blood group was found to be considerably higher among case mothers (14.39 [1.57–32.27]). A higher odds of OCs w...

Tobacco Induced Diseases, Mar 1, 2018

Journal of Oral Disease Marker, 2018

How to cite this article: Sivakumar S. The increasing prevalence of edentulous state among childr... more How to cite this article: Sivakumar S. The increasing prevalence of edentulous state among children in Malaysia.