Snjezana Vlah - Academia.edu (original) (raw)

Papers by Snjezana Vlah

Uvod: Cilj ovog is tra ži va nja bio je us po re di ti ana li za tor za pret ra ge uz bo lesni ka... more Uvod: Cilj ovog is tra ži va nja bio je us po re di ti ana li za tor za pret ra ge uz bo lesni ka (en gl. poi nt-o f-ca re tes ti ng, POCT) Gem® Pre mierTM 4000 s re fe ren tnim ana li za to ri ma. Po seb na je paž nja pos ve će na me to di mje re nja kon cen tra ci je tHb/HCT na ana li za to ri ma za POCT. Mate ri ja li i me to de: Us po re di li smo ana li tič ki uči nak ana li za to ra Gem® PremierTM 4000 s učin ci ma ana li za to ra Ci ba Cor ni ng 865, Gem® Pre mierTM 3000 i Di men sion RxL, kod od re đi va nja kon cen tra ci je pa ra me ta ra aci do-ba zič nog sta tu sa (pH, pCO2, pO2), elek tro li ta, me ta bo li ta, he mog lo bi na i he ma tok ri ta. Za ana li za tor Gem® Pre mierTM 4000 iz ra ču na te su nep re ciz nos ti unu tar se ri je i iz da na u dan. 200 uzo ra ka pu ne kr vi je ana li zi ra no u raz dob lju od 30 da na.

Clinical Laboratory, 2013

Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is u... more Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is used for risk assessment in patients with ACS as well as unstable angina pectoris, it is very important to measure its concentration accurately and precisely. Methods: Here we report a case in which there was a significant difference in the cTnI concentrations measured by three different methods, which was detected in one patient's sera during preoperative evaluation for cardiac surgery. Results: Due to variations in the results for the cTnI concentrations (0.62; 0.13; 0.89 microg/L), the question was raised about the possibility of an interference known to occur in especially rare situations. A 76-year-old male was operated, temporal elevation and subsequent decrease in the concentrations of cTnI were monitored. Conclusions: It was observed that results obtain with different assays are not comparable.

Objective: The aim of this study was to compare a new point-of-care testing (POCT) Gem® Premier™ ... more Objective: The aim of this study was to compare a new point-of-care testing (POCT) Gem® Premier™ 4000 analyzer with reference analyzers. Special attention was given to the technology of measuring the concentration of hemoglobin and hematocrit on POCT analyzers. Materials and methods: Analytical performance of the Gem® Premier™ 4000 was compared with Ciba Corning 865, Gem® Premier™ 3000 and Dimension RxL analyzers for pH, pCO2, pO2, electrolytes, metabolites and for hemoglobin/hematocrit. Within-run and between-run imprecisions have been determined for the Gem® Gem® Premier™ 4000 analyzer. In the period of 30 days, 200 whole blood samples were analyzed. Results: Satisfactory results were obtained for within-run imprecision for all study analytes (CV ≤ 4.89%), except for pO2 (CV = 14.66%) and for between-run imprecision for all parameters (CV ≤ 4.41%) except for lactate (Level I: CV = 8%, Level II: CV = 6.59%). The correlation with the comparative methods was satisfactory, correlation...

Biochemia Medica, 2009

Ana li tič ki uči nak analiza to ra Gem ® Pre mier TM 4000-us po re dno is tra ži va nje Ana lyti... more Ana li tič ki uči nak analiza to ra Gem ® Pre mier TM 4000-us po re dno is tra ži va nje Ana lyti cal per for man ce of the Gem ® Pre mier TM 4000-a com parison stu dy Snje ža na Hrabrić Vlah 1 , Šte fi ca Dvor nik, Dino Grdović Za vod za la bo ra to rij sku di jag nos ti ku, Kli nič ki bol nič ki cen tar Ri je ka, Rijeka De par tme nt of Cli ni cal La bo ra to ry Diag nos ti cs, Ri je ka Cli ni cal Hos pi tal Cen ter, Rijeka, Croatia

Background: HbA1c as valuable marker in management of diabetes is measured in the most of medical... more Background: HbA1c as valuable marker in management of diabetes is measured in the most of medical laboratories in Croatia. Aim of this study is to present the results of external quality control assessment (EQA) in Croatian medical laboratories for HbA1c. Material and methods: Results were obtained from 93 laboratories that participated in cycle of EQA scheme in 2013.The control sample was commercial, lyophilized human blood specimen with normal HbA1c value. The results were entered on-line, as a dual system of reporting: DCCT (%) and IFCC (mmol/mol), and DCCT results were analyzed. Outliers (N=14) were excluded according to Tukey´s model and mean (X), standard deviation (SD) and coefficient of variation (CV) were calculated. According to quality specifications established in CROQALM, the allowable deviation from the mean was ±5%. Results: The results were divided in two groups according to the method (immunoassay and colorimetric method). For immunoassay methods (82 participants, s...

Clinical Laboratory, 2013

Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is u... more Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is used for risk assessment in patients with ACS as well as unstable angina pectoris, it is very important to measure its concentration accurately and precisely. Methods: Here we report a case in which there was a significant difference in the cTnI concentrations measured by three different methods, which was detected in one patient's sera during preoperative evaluation for cardiac surgery. Results: Due to variations in the results for the cTnI concentrations (0,62; 0,13; 0,89 µg/L), the question was raised about the possibility of an interference known to occur in especially rare situations. A 76-year-old male was operated, temporal elevation and subsequent decrease in the concentrations of cTnI were monitored. Conclusions: It was observed that results obtain with different assays are not comparable.

Clinical Laboratory, 2013

Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is u... more Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is used for risk assessment in patients with ACS as well as unstable angina pectoris, it is very important to measure its concentration accurately and precisely. Methods: Here we report a case in which there was a significant difference in the cTnI concentrations measured by three different methods, which was detected in one patient's sera during preoperative evaluation for cardiac surgery. Results: Due to variations in the results for the cTnI concentrations (0,62; 0,13; 0,89 µg/L), the question was raised about the possibility of an interference known to occur in especially rare situations. A 76-year-old male was operated, temporal elevation and subsequent decrease in the concentrations of cTnI were monitored. Conclusions: It was observed that results obtain with different assays are not comparable.

Clinical Laboratory, 2013

Biochemia Medica, 2009

Clinical Laboratory, 2013

Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is u... more Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is used for risk assessment in patients with ACS as well as unstable angina pectoris, it is very important to measure its concentration accurately and precisely. Methods: Here we report a case in which there was a significant difference in the cTnI concentrations measured by three different methods, which was detected in one patient's sera during preoperative evaluation for cardiac surgery. Results: Due to variations in the results for the cTnI concentrations (0,62; 0,13; 0,89 µg/L), the question was raised about the possibility of an interference known to occur in especially rare situations. A 76-year-old male was operated, temporal elevation and subsequent decrease in the concentrations of cTnI were monitored. Conclusions: It was observed that results obtain with different assays are not comparable.

Clinical Laboratory, 2013

Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is u... more Background: Since cTnI assay is leading test in diagnostic of myocardial infarctions, and it is used for risk assessment in patients with ACS as well as unstable angina pectoris, it is very important to measure its concentration accurately and precisely. Methods: Here we report a case in which there was a significant difference in the cTnI concentrations measured by three different methods, which was detected in one patient's sera during preoperative evaluation for cardiac surgery. Results: Due to variations in the results for the cTnI concentrations (0,62; 0,13; 0,89 µg/L), the question was raised about the possibility of an interference known to occur in especially rare situations. A 76-year-old male was operated, temporal elevation and subsequent decrease in the concentrations of cTnI were monitored. Conclusions: It was observed that results obtain with different assays are not comparable.