Sohail Ahmad - Academia.edu (original) (raw)

Papers by Sohail Ahmad

The Journal of Infectious Diseases, Dec 1, 1989

European Journal of Clinical Investigation, Dec 1, 2010

Background Peritoneal fibrosis manifests clinically as membrane failure or encapsulating peritone... more Background Peritoneal fibrosis manifests clinically as membrane failure or encapsulating peritoneal sclerosis (EPS). There are no clinical or biochemical tests to determine the rate of progression of peritoneal fibrosis. CCL18 ⁄ pulmonary and activation-regulated chemokine (PARC) is profibrotic and stimulates collagen production independent of the effect of transforming growth factor beta. This has not been studied in peritoneal dialysis (PD) patients.

RSC Adv., 2016

Meso and β-substituted free base and zinc metallated thiazolidinone–porphyrin conjugates were syn... more Meso and β-substituted free base and zinc metallated thiazolidinone–porphyrin conjugates were synthesized by one pot four component Knoevenagel condensation by utilizing substituted amines, carbon disulfide, ethyl chloroacetate and porphyrin aldehydes.

Sarhad Journal of Agriculture, 2013

Pakistan Veterinary Journal, Jun 3, 2014

A breeding trial under controlled farm conditions was carried out to estimate serum estrogen and ... more A breeding trial under controlled farm conditions was carried out to estimate serum estrogen and progesterone spectrum over the entire gestation length in Kari ewes belonging to three subtypes. Kari is an exceptional breed within ovine species that gestates in variable length of period (85-154 days). Ewes were bred through hand mating, using rams from respective subtype based on the history of pregnancy duration (A:<110, B:111-130 and C:131-150 days). Upon lambing, the gestation length (GL) of ewes within each subtype was found at variance. Blood-serum sampling was carried out weekly, commencing after mating and continued until lambing. Samples collected from open ewes were discarded upon pregnancy confirmation examined through ultrasonography. The serum was analyzed for progesterone and estrogen profiles. The maximum progesterone concentration (24.2 ng/ml) observed in group C, during the 19 th week of its gestation. Advancement in gestation boosted the peripheral blood progesterone concentration but in an undulating pattern. Serum progesterone at the start of pregnancy was at lower (2.1 ng/ml), reached at its peak (24.2 ng/ml) towards the end of gestation and dropped to (12.2 ng/ml) right after lambing. Maximum estrogen level (43.86 ng/ml) was observed on in group C, followed by B. Group A had the lower estrogen level with a minimal undulation throughout the gestation length. Estrogen was found fluctuating across the entire gestation period in ewes irrespective of their gestation length, which surged up towards the pregnancy termination.

Indian journal of orthopaedics

Gap nonunion of long bones is a challenging problem, due to the limitation of conventional recons... more Gap nonunion of long bones is a challenging problem, due to the limitation of conventional reconstructive techniques more so if associated with infection and soft tissue defect. Treatment options such as autograft with non-vascularized fibula and cancellous bone graft, vascularized bone graft, and bone transportation are highly demanding on the part of surgeons and hospital setups and have many drawbacks. This study aims to analyze the outcome of patients with wide diaphyseal bone gap treated with induced-membrane technique (Masquelet technique). This study included 9 patients (7 males and 2 females), all with tibial bone-gap. Eight of the 9 patients were infected and in 3 patients there was associated large soft tissue defect requiring flap cover. This technique is two-stage procedure. Stage I surgery included debridement, fracture stabilization, application of spacer between bone ends, and soft tissue reconstruction. Stage II surgery included removal of spacer with preservation of...

Theoretical and Empirical Researches in Urban Management, 2010

Climate change has been emerged as a major challenge for the sustainable human settlement. The re... more Climate change has been emerged as a major challenge for the sustainable human settlement. The recent studies have established scientific evidences for climate change. This paper presents impacts of climate change in the urban India, which has about 30 percent of population and expected to grow over 800 million by next 50 years. Citizens are already facing adverse impact of climate change, which is evenly spread throughout the country and mostly to vulnerable citizens. India's expenditure on adaptation measures was exceeded 2.6 percent of the GDP in 2006-07 shows the magnitude of monetary loss by climate change. Due to complexity of issues, systematic strategies are needed for adaptation and mitigation. In the light of 'National Action Plan on Climate Change' two urban sectors viz. urban transportation and municipal solid waste management are assessed and suggestions have been made for mitigation strategies. This study is broadly based on published researches and documents. Findings reveal that yet the climate change is not taken seriously by policy makers, hence blue print for mitigation haven't placed. Findings suggest systematic mitigation measures for sustainable development which will lead to inclusive growth too. The need for collaborative planning among various stakeholders is emphasized.

Turkish Journal of Veterinary and Animal Sciences, Feb 14, 2011

Fertility and Sterility, Jan 8, 2010

Objective: To investigate the impact of Withania somnifera roots on semen profile, oxidative biom... more Objective: To investigate the impact of Withania somnifera roots on semen profile, oxidative biomarkers, and reproductive hormone levels of infertile men. Design: Prospective study. Setting: Patient(s): Seventy-five normal healthy fertile men (control subjects) and 75 men undergoing infertility screening. Intervention(s): High-performance liquid chromatography assay procedure for quantization of vitamin A and E in seminal plasma. Biochemical parameters in seminal plasma were estimated by standard spectrophotometric procedures. Estimation of T, LH, FSH, and PRL in blood serum by RIA methods. Main Outcome Measures(s): Before and after the treatment, seminal plasma biochemical parameters, antioxidant vitamins, and serum T, LH, FSH, and PRL levels were measured. Result(s): Withania somnifera inhibited lipid peroxidation and protein carbonyl content and improved sperm count and motility. Treatment of infertile men recovered the seminal plasma levels of antioxidant enzymes and vitamins A, C, and E and corrected fructose. Moreover, treatment also significantly increased serum T and LH and reduced the levels of FSH and PRL. Conclusion(s): The treatment with W. somnifera effectively reduced oxidative stress, as assessed by decreased levels of various oxidants and improved level of diverse antioxidants. Moreover, the levels of T, LH, FSH and PRL, good indicators of semen quality, were also reversed in infertile subjects after treatment with the herbal preparation. (Fertil Steril Ò 2010;94:989-96.

Sarhad Journal of Agriculture, 2009

Abstract This research paper attempts to determine effectiveness of different demonstration plots... more Abstract This research paper attempts to determine effectiveness of different demonstration plots adopted by Aga Khan Rural Support Programme (AKRSP) for agricultural technology transfer in district Chitral. The research was carried out in district Chitral during 2005 in ...

Journal of Molecular Catalysis A: Chemical, 2014

ABSTRACT

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2006

An analysis of clinicopathological features of 240 cases presenting as mass in nasal cavity, para... more An analysis of clinicopathological features of 240 cases presenting as mass in nasal cavity, paranasal sinuses and nasopharynx observed, both retrospectively and prospectively, over a period of 5 years in Jawaharlal Nehru Medical College. Aligarh. The incidence of masses in nasal cavity, paranasal sinuses and nasopharynx was 34.3 cases per year. Amongst the 240 cases studied, there were 144 cases (60%) of non-neoplastic lesions, 56 cases (23.33%) of benign lesions and 40 cases (16.67%) of malignant lesions. All age groups were involved and the mean age of presentation with the increasing age were: - non-neoplastic (22.5 years), benign tumors (26.8 years) and malignant tumors (35.3 years). The male to female ratio was 1.7:1 for non-neoplastic lesions; 3:1 for benign tumors: and 2.3:1 for malignant lesions. In this study maximum number of cases were present in nasal cavity (65%) followed by paranasal sinuses (20%) and least number of cases involved the nasopharynx (15%). The relative ...

Journal of radiological protection : official journal of the Society for Radiological Protection, 2007

Near-surface or shallow land disposal of radioactive waste has been the primary practice at the P... more Near-surface or shallow land disposal of radioactive waste has been the primary practice at the Pakistan Institute of Nuclear Science and Technology (PINSTECH). The adopted choice of this mode of disposal has been based on a study of the site and the quality and quantity of waste generated at the 5 MW reactor with HEU fuel. Specific measures regarding the radiation safety of the workers and environmental protection have been adopted. The waste disposal operations are conducted to meet local regulatory requirements, IAEA recommendations and internationally endorsed principles such as ALARA (as low as reasonably achievable - economic, social and other relevant factors being considered). The data obtained through the years of operational and management experience have manifested the robustness of the disposal system and reliability of the disposal criterion, and have also served to further refine the latter. Consequently, confidence in the current shallow-land-burial practices has incr...

The Journal of organic chemistry, Jan 24, 2015

The 3+1 condensation of symmetrical 16-selena/telluratripyrranes with symmetrical selenophene-2,5... more The 3+1 condensation of symmetrical 16-selena/telluratripyrranes with symmetrical selenophene-2,5-diols / tellurophene2,5-diols in presence of BF3-etheratre or BF3-methanol followed by oxidation with DDQ gave 5,10-porphodimethenes; whereas with unsymmetrical selenophene-2,5-diols / tellurophene-2,5-diols gave 5-porphomethenes. Further the reaction of unsymmetrical 16-selena/telluratripyrranes with symmetrical selenophene-2,5-diols / tellurophene-2,5-diols gave the corresponding porphotrimethenes; whereas with unsymmetrical selenophene-2,5-diols / tellurophene-2,5-diols gave the 5,15-porphodimethenes. The structures of different products were characterized by IR, 1H, 13C NMR, 1H-1H COSY, CHN analysis and mass spectrometry. The binding of mercury with above calix[4]phyrins had been observed in the decreasing order of porphodimethenes ˃ porphomethenes ˃ porphotrimethenes by UV-vis and 1H NMR spectroscopy.

$Research paper thumbnail of Fixation using cannulated screws and fibular strut grafts for fresh femoral neck fractures with posterior comminution$

Journal of orthopaedic surgery (Hong Kong), 2012

To evaluate the use of fibular grafting for fresh femoral neck fractures with posterior comminuti... more To evaluate the use of fibular grafting for fresh femoral neck fractures with posterior comminution. 18 women and 15 men aged 20 to 60 years underwent osteosynthesis and fibular strut grafting supplemented with 7.0-mm cannulated hip screws for Garden grades III (n=21) and IV (n=12) femoral neck fractures associated with posterior comminution. All fractures were reduced by closed methods, and no hip was aspirated. Clinical and radiological outcomes were evaluated. The mean delay in presentation after injury was 3.2 (range, 1-12) days. The mean delay in operation was 8.8 (range, 5-21) days. The mean follow-up period was 2 (range, 1-4) years. According to the Harris hip score, outcome was good to excellent in 20 patients, fair in 7, and poor in 6. 27 of the 33 patients achieved bone union after a mean of 4.7 (range, 4.2-7) months. In 5 patients, the bone was united with a mean of 10º of varus collapse and a mean of 1 cm of shortening. Six patients had non-union. Other complications inc...

African Journal of Biotechnology, 2010

Morphological and genetic diversity among the three neighboring sheep breeds native to Central va... more Morphological and genetic diversity among the three neighboring sheep breeds native to Central valley of Khyber Pukhtunkhwa (KP, Pakistan) was investigated. A total number of 138 non relative individuals of Balkhi (46), Hashtnagri (44) and Michni (48) was sampled for morphological as well as molecular characters using 31 ovine specific SSR markers. Morphological observations and morphometric traits varied significantly among different sheep breeds. Balkhi having usually brown or white colour, with a tucked up fat tail was the larger breed. Hashtnagri is a medium sized breed; body covered with white wool, having long white tail, with a tail switch. The body colour of Michni sheep was usually brown or some times white. This breed is comparatively small in size with longer fat tail, hanging near (33.3%) or below (66.7%) hock. Total number of 119 alleles was identified with mean number of 3.8 alleles per locus, ranging from 2 to 8. Twelve unique alleles were identified in Michni population at different loci. Average gene diversity was higher in Michni (0.561). Inbreeding estimate (F IT ) was significantly higher (27.1%) among three breeds and was highest between Balkhi and Hashtnagri (31%), similarly highest gene flow (Nm = 60.4) and lowest population differentiation (F ST = 4.3%) was estimated between these two breeds. Maximum genetic distance was observed between Balkhi and Michni; however, Balkhi was genetically closed to Hashtnagri population. Balkhi and Michni were assigned at high accuracy to their respective population; however, the identity of Hashtnagri is obscure.

International Journal of Immunopharmacology, 1984

Beta 1 -3 polyglucose or glucan, an extract of cell wall of Saccharomyces cerevisiae, has been su... more Beta 1 -3 polyglucose or glucan, an extract of cell wall of Saccharomyces cerevisiae, has been successfully employed in this laboratory as an effective immunopotentiator in experimental studies on amoebiasis. An antigen extract from Entamoeba histolytica was combined with/3, 1 -3 glucan for immunizing guinea pigs. In order to study the effectiveness of such vaccine preparations, several batches of guinea pigs were immunized with amoeba antigen alone, and in combination with various immunoadjuvants. Antigen inoculations were carried out via intraperitoneal route. Protective immune responses were obtained against amoeba antigen by using glucan as an adjuvant partner. The study showed that glucan can be safely used as an effective immune enhancer.

Next generation infrastructure systems for eco-cities, 2010

Abstract This paper uses 2001 census data from India to identify and measure the spatial structur... more Abstract This paper uses 2001 census data from India to identify and measure the spatial structure and intensity of urban deprivation in Delhi. We analyze fourteen indicators from the census using a factor analysis to identify the specific type of deprivation and consequently ...