Chiara Spanu - Academia.edu (original) (raw)
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Papers by Chiara Spanu
ACS applied polymer materials, Feb 13, 2024
Progress in additive manufacturing, Apr 6, 2024
Nowadays, most of the commercial resins for VP are composed of (meth)acrylated urethanes, as they... more Nowadays, most of the commercial resins for VP are composed of (meth)acrylated urethanes, as they are cheap and provide good mechanical properties to the thermosets produced by their photocuring. However, such urethanes are still produced using toxic and polluting isocyanates, though alternative pathways exploiting cyclic carbonates and biobased amines are arising. Unfortunately, the use of biobased amines and carbonates to produce (meth)acrylate urethanes often leads to the formation of solid products that display poor solubility in the liquid components of photocurable resins. In this work, we describe the synthesis of fully biobased diurethanediols using a biobased diamine and bioderived carbonates functionalized with itaconic acid moieties that are liquid at room temperature and that can be efficiently formulated with (meth)acrylic and itaconic acid-based formulations for VP leading to 3D printed materials with good mechanical properties, comparable to those of commercially available non-biobased alternatives. In fact, depending on the resin formulations, the addition of diurethanediols diitaconates led to the obtainment of 3D printed materials with elastic moduli as high as 1 GPa, and tensile strengths over 30 MPa, and biobased contents as high as 90 wt.%. These products may serve as candidates for the replacement of isocyanate-based components with the aim of increasing the sustainability of resins' manufacturing for VP.
Pharmaceutics, Oct 18, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
New Journal of Chemistry
This work shows the synthesis of a drug delivery system made of casein nanoparticles able to host... more This work shows the synthesis of a drug delivery system made of casein nanoparticles able to host hydrophobic molecule and to be functionalized with an aptamer targeting the epidermal growth...
Biomolecules
Microcrystalline cellulose (MCC) is an emerging material with outstanding properties in many scie... more Microcrystalline cellulose (MCC) is an emerging material with outstanding properties in many scientific and industrial fields, in particular as an additive in composite materials. Its surface modification allows for the fine-tuning of its properties and the exploitation of these materials in a plethora of applications. In this paper, we present the covalent linkage of a luminescent Ir-complex onto the surface of MCC, representing the first incorporation of an organometallic luminescent probe in this biomaterial. This goal has been achieved with an easy and sustainable procedure, which employs a Bronsted-acid ionic liquid as a catalyst for the esterification reaction of -OH cellulose surface groups. The obtained luminescent cellulose microcrystals display high and stable emissions with the incorporation of only a small amount of iridium (III). Incorporation of MCC-Ir in dry and wet matrices, such as films and gels, has been also demonstrated, showing the maintenance of the luminescen...
ACS applied polymer materials, Feb 13, 2024
Progress in additive manufacturing, Apr 6, 2024
Nowadays, most of the commercial resins for VP are composed of (meth)acrylated urethanes, as they... more Nowadays, most of the commercial resins for VP are composed of (meth)acrylated urethanes, as they are cheap and provide good mechanical properties to the thermosets produced by their photocuring. However, such urethanes are still produced using toxic and polluting isocyanates, though alternative pathways exploiting cyclic carbonates and biobased amines are arising. Unfortunately, the use of biobased amines and carbonates to produce (meth)acrylate urethanes often leads to the formation of solid products that display poor solubility in the liquid components of photocurable resins. In this work, we describe the synthesis of fully biobased diurethanediols using a biobased diamine and bioderived carbonates functionalized with itaconic acid moieties that are liquid at room temperature and that can be efficiently formulated with (meth)acrylic and itaconic acid-based formulations for VP leading to 3D printed materials with good mechanical properties, comparable to those of commercially available non-biobased alternatives. In fact, depending on the resin formulations, the addition of diurethanediols diitaconates led to the obtainment of 3D printed materials with elastic moduli as high as 1 GPa, and tensile strengths over 30 MPa, and biobased contents as high as 90 wt.%. These products may serve as candidates for the replacement of isocyanate-based components with the aim of increasing the sustainability of resins' manufacturing for VP.
Pharmaceutics, Oct 18, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
New Journal of Chemistry
This work shows the synthesis of a drug delivery system made of casein nanoparticles able to host... more This work shows the synthesis of a drug delivery system made of casein nanoparticles able to host hydrophobic molecule and to be functionalized with an aptamer targeting the epidermal growth...
Biomolecules
Microcrystalline cellulose (MCC) is an emerging material with outstanding properties in many scie... more Microcrystalline cellulose (MCC) is an emerging material with outstanding properties in many scientific and industrial fields, in particular as an additive in composite materials. Its surface modification allows for the fine-tuning of its properties and the exploitation of these materials in a plethora of applications. In this paper, we present the covalent linkage of a luminescent Ir-complex onto the surface of MCC, representing the first incorporation of an organometallic luminescent probe in this biomaterial. This goal has been achieved with an easy and sustainable procedure, which employs a Bronsted-acid ionic liquid as a catalyst for the esterification reaction of -OH cellulose surface groups. The obtained luminescent cellulose microcrystals display high and stable emissions with the incorporation of only a small amount of iridium (III). Incorporation of MCC-Ir in dry and wet matrices, such as films and gels, has been also demonstrated, showing the maintenance of the luminescen...